Computational and RNA Biology

  1. Published

    "Out of the Can": A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus

    Machado, A. M., Tørresen, O. K., Kabeya, N., Couto, A., Petersen, Bent, Felicio, M., Campos, P. F., Fonseca, E., Bandarra, N., Lopes-Marques, M., Ferraz, R., Ruivo, R., Fonseca, M. M., Jentoft, S., Monroig, Ó., Rodrigues da Fonseca, Rute Andreia & Castro, L. F. C., 2018, In: Genes. 9, 10, p. 1-13 485.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published
  3. Published

    3-methylcholanthrene induces differential recruitment of aryl hydrocarbon receptor to human promoters

    Pansoy, A., Ahmed, S., Valen, E., Sandelin, Albin Gustav & Matthews, J., 2010, In: Toxicological Sciences. 117, 1, p. 90-100 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    57miRNA regulation during oncogene-induced senescence


    Christoffersen, N. R., Frankel, Lisa, Klausen, M., Jacobsen, A., Krogh, Anders & Lund, Anders H., May 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  5. Published

    Chlorobium Tepidum: Insights into the Structure, Physiology, and Metabolism of a Green Sulfur Bacterium Derived from the Complete Genome Sequence

    Frigaard, Niels-Ulrik, Chew, A. G. M., Li, H., Maresca, J. A. & Bryant, D. A., 2003, In: Photosynthesis Research. 78, 2, p. 93-117 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Chlorobium tepidum mutant lacking bacteriochlorophyll c made by inactivation of the bchK gene, encoding bacteriochlorophyll c synthase

    Frigaard, Niels-Ulrik, Voigt, G. D. & Bryant, D. A., 2002, In: Journal of Bacteriology. 184, 12, p. 3368-3376 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    E. coli dihydroorotate dehydrogenase reveals structural and functional distinctions between different classes of dihydroorotate dehydrogenases.

    Nørager, S., Jensen, K. F., Björnberg, O. & Larsen, Sine, 2002, In: Structure. 10, p. 1211-1223

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    De novo pathway-based biomarker identification

    Alcaraz, N., List, M., Batra, R., Vandin, F., Ditzel, H. J. & Baumbach, J., 19 Sep 2017, In: Nucleic Acids Research. 45, 16, 11 p., e151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    De novo assembly of a haplotype-resolved human genome

    Cao, H., Wu, H., Luo, R., Huang, S., Sun, Y., Tong, X., Xie, Y., Liu, B., Yang, H., Zheng, H., Li, J., Li, B., Wang, Y., Yang, F., Sun, P., Liu, S., Gao, P., Huang, H., Sun, J., Chen, D. & 21 others, He, G., Huang, W., Huang, Z., Li, Y., Tellier, L. C. A. M., Liu, X., Feng, Q., Xu, X., Zhang, X., Bolund, L., Krogh, Anders, Kristiansen, Karsten, Drmanac, R., Drmanac, S., Nielsen, R., Li, S., Wang, J., Yang, H., Li, Y., Wong, G. K. & Wang, J., 2015, In: Nature Biotechnology. 33, 6, p. 617-626 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    De novo whole-genome assembly and resequencing resources for the roan (Hippotragus equinus), an iconic African antelope

    Gonçalves, M., Siegismund, Hans Redlef, Van Vuuren, B. J., Koepfli, K., Ferrand, N. & Godinho, R., 2021, In: G3: Genes, Genomes, Genetics. 11, 2, 9 p., jkab002.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation

    Hansen, H. T., Rasmussen, S. H., Adolph, S. K., Plass, M., Krogh, Anders, Sanford, J., Nielsen, Finn Cilius & Christiansen, Jan, 2015, In: Genome Biology (Online Edition). 16, 16 p., 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Giraffa camelopardalis

    Liu, C., Gao, J., Huang, J., Wang, W., Heller, Rasmus & Qiu, Q., 2021, In: Trends in Genetics. 37, 9, p. 860-861 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  14. Published

    In vivo, genome-wide profiling of endogenously tagged chromatin-binding proteins with spatial and temporal resolution using NanoDam in Drosophila

    Tang, J. L. Y., Krautz, Robert, Llorà-Batlle, O., Hakes, A. E., Fox, P. M. & Brand, A. H., 2022, In: STAR Protocols. 3, 4, 30 p., 101788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Lactobacillus rhamnosus GG Genomic and Phenotypic Stability in an Industrial Production Process

    Strickertsson, Marianne Stage, Wichmann, A., Jørgensen, M., Vera-Jimenéz, N. I., Wielje, M., Nielsen, Dennis Sandris, Sandelin, Albin Gustav, Chen, Y. & Baker, A., 2020, In: Applied and Environmental Microbiology. 86, 6, 15 p., e02780-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mammuthus sp. (Early and Middle Pleistocene Mammoths)

    Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D., van der Valk, T., Dehasque, M., Götherström, A. & Dalén, L., 2021, In: Trends in Genetics. 37, 7, p. 682-683 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  17. Published

    SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

    Damas, N. D., Marcatti, M., Côme, Christophe Roger Michel, Christensen, L., Nielsen, M. M., Baumgartner, R., Gylling, H. M., Maglieri, G., Friis, Carsten, Seemann, Ernst Stefan, Rapin, N., Thézenas, S., Vang, S., Ørntoft, T., Andersen, C. L., Pedersen, J. S. & Lund, Anders H., 22 Dec 2016, In: Nature Communications. 7, 14 p., 13875.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    SigniSite: identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments

    Jessen, L. E., Hoof, I., Lund, O. & Nielsen, M., 2013, In: Nucleic Acids Research. 41, W1, p. W286-W291 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    ngsTools : methods for population genetics analyses from next-generation sequencing data

    Fumagalli, M., Vieira, Filipe Garrett, Linderoth, T. & Nielsen, Rasmus, 2014, In: Bioinformatics. 30, 10, p. 1486-1487 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Alle bakterier deler gener ved horisontal overførsel

    Frigaard, Niels-Ulrik, 2007, In: Dansk Kemi. 88, 5, p. 28-31 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A Chinese indicine pangenome reveals a wealth of novel structural variants introgressed from other Bos species

    Dai, X., Bian, P., Hu, D., Luo, F., Huang, Y., Jiao, S., Wang, X., Gong, M., Li, R., Cai, Y., Wen, J., Yang, Q., Deng, W., Nanaei, H. A., Wang, Y., Wang, F., Zhang, Z., Rosen, B. D., Heller, Rasmus & Jiang, Y., Aug 2023, In: Genome Research. 33, 8, p. 1284-1298 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A Combined Transmembrane Topology and Signal Peptide Prediction Method

    Kall, L., Krogh, Anders & Sonnhammer, E. L., 2004, In: Journal of Molecular Biology. Vol. 338 (5), p. 1027-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

    Garland, W., Comet, I., Wu, M., Radzisheuskaya, A., Rib, Leonor, Vitting-Seerup, K., Lloret-Llinares, M., Sandelin, Albin Gustav, Helin, K. & Jensen, T. H., 2019, In: Cell Reports. 29, 7, p. 1800-1811 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A Generative Angular Model of Protein Structure Evolution

    Golden, M., Garcia-Portugues, E., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., Aug 2017, In: Molecular Biology and Evolution. 34, 8, p. 2085-2100

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A New Paradigm for General Architecture Routing

    Paluszewski, M., Winter, Pawel & Zachariasen, M., 2004, Proceedings of the 14th ACM Great Lakes Symposium on VLSI. New York, NY, USA: Association for Computing Machinery, p. 202-207

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  26. Published

    A Probabilistic Programming Approach to Protein Structure Superposition

    Sanz Moreta, Lys, Al-Sibahi, A. S., Theobald, D., Bullock, W., Rommes, B. N., Manoukian, Andreas & Hamelryck, Thomas Wim, 2019, 2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2019. Baruzzo, G., Daberdaku, S., Di Camillo, B., Furini, S., Giordano, E. D. & Nicosia, G. (eds.). IEEE, 5 p. 8791469

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  27. Published

    A Targeted Multiomics Approach to Identify Biomarkers Associated with Rapid eGFR Decline in Type 1 Diabetes

    Limonte, C. P., Valo, E., Montemayor, D., Afshinnia, F., Ahluwalia, T. S., Costacou, T., Darshi, M., Forsblom, C., Hoofnagle, A. N., Groop, P-H., Miller, R. G., Orchard, T. J., Pennathur, S., Rossing, P., Sandholm, N., Snell-Bergeon, J. K., Ye, H., Zhang, J., Natarajan, L., De Boer, I. H. & 1 others, Sharma, K., 2020, In: American Journal of Nephrology. 51, 10, p. 839-848 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome

    Wu, G., Schmid, M., Rib, Leonor, Polak, P., Meola, N., Sandelin, Albin Gustav & Jensen, T. H., 2020, In: Cell Reports. 30, 7, p. 2387-2401, e1-e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A YTHDF–PABP interaction is required for m6A-mediated organogenesis in plants

    Tankmar, Mathias Due, Reichel, M., Arribas Hernandez, Laura & Brodersen, Peter, 2023, In: EMBO Reports. 24, 12, 19 p., e57741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A code for transcription initiation in mammalian genomes

    Frith, M. C., Valen, E. D., Krogh, Anders, Hayashizaki, Y., Carninci, P. & Sandelin, Albin Gustav, 2007, In: Genome Research. 18, 1, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

    Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, Nielsen, R., Albrechtsen, Anders & Hansen, Torben, 2014, In: Nature. 512, 7513, p. 190-193 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  32. Published

    A common Greenlandic Inuit BRCA1 RING domain founder mutation

    Hansen, T. V. O., Ejlertsen, Bent Laursen, Albrechtsen, Anders, Bergsten, E., Bjerregaard, P., Hansen, T., Myrhoj, T., Nielsen, P. B., Timmermans-Wielenga, V., Andersen, M. K., Jonson, L. & Nielsen, F. C., 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 69-76 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]

    Orengo, C., Velankar, S., Wodak, S., Zoete, V., Bonvin, A. M. J. J., Elofsson, A., Feenstra, K. A., Gerloff, D. L., Hamelryck, T., Hancock, J. M., Helmer-Citterich, M., Hospital, A., Orozco, M., Perrakis, A., Rarey, M., Soares, C., Sussman, J. L., Thornton, J. M., Tuffery, P., Tusnady, G. & 3 others, Wierenga, R., Salminen, T. & Schneider, B., 2020, In: F1000Research. 9, 27 p., 278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

    Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

    Gabrielaite, M., Torp, M., Rasmussen, M., Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C., Kinalis, S., Madsen, M., Yde, C., Rønn, O. L., Marvig, R., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, bioRxiv, 29 p.

    Research output: Working paperPreprintResearch

  36. Published

    A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

    Olsen, L. R., Simon, C., Kudahl, U. J., Bagger, F. O., Winther, Ole, Reinherz, E. L., Zhang, G. L. & Brusic, V., 2015, In: B M C Medical Genomics. 8, Suppl 4, 6 p., 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A draft genome sequence of the elusive giant squid, Architeuthis dux

    da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, Osório, H., Winkelmann, I., Simakov, O., Rasmussen, Simon, Rahman, M. Z., Pisani, D., Vinther, J., Jarvis, E., KU, thw266, Strugnell, J. M., Castro, L. F. C., Fedrigo, O., Patricio, M., Li, Q., Rocha, S., Antunes, A., Wu, Y., Ma, B., Sanges, R., Vinar, T., Blagoev, B., Sicheritz-Pontén, Thomas, Nielsen, Rasmus & Gilbert, M Thomas P, 2020, In: GigaScience. 9, 1, 12 p., giz152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

    Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A fluorescent substrate for carbon-phosphorus lyase: towards the pathway for organophosphonate metabolism in bacteria

    He, S., Lou, Y., Hove-Jensen, B. & Zechel, D. L., 2009, In: Bioorganic & Medicinal Chemistry Letters. 19, 20, p. 5954-5957

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A generative, probabilistic model of local protein structure

    Boomsma, Wouter, Mardia, K. V., Taylor, C. C., Ferkinghoff-Borg, J., Krogh, Anders & Hamelryck, Thomas Wim, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 26, p. 8932-8937 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A genetic analysis of carbon-nanotube-binding proteins

    Brown, Stanley, Jespersen, T. S. & Nygård, Jesper, 2008, In: Small. 4, 4, p. 416-420

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A genome-wide scan in affected sib-pairs with idiopathic recurrent miscarriage suggests genetic linkage

    Kolte, A. M., Nielsen, Henriette Svarre, Moltke, Ida, Degn, B., Pedersen, B., Sunde, L., Nielsen, Finn Cilius & Christiansen, O. B., 2011, In: Molecular Human Reproduction. 17, 6, p. 379-385 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A genomic history of aboriginal Australia

    Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, A., Barbieri, C., Dupanloup, I. & 55 others, Eriksson, A., Margaryan, Ashot, Moltke, Ida, Pugach, I., Korneliussen, Thorfinn Sand, Levkivskyi, I. P., Moreno Mayar, J. Víctor, Ni, S., Racimo, F., Sikora, Martin, Xue, Y., Aghakhanian, F. A., Brucato, N., Brunak, Søren, Campos, P., Clark, W., Ellingvåg, S., Fourmile, G., Gerbault, P., Injie, D., Koki, G., Leavesley, M., Logan, B., Lynch, A., Matisoo-Smith, E. A., McAllister, P. J., Mentzer, A. J., Metspalu, M., Migliano, A. B., Murgha, L., Phipps, M. E., Pomat, W., Reynolds, D., Ricaut, F., Siba, P., Thomas, M. G., Wales, T., Wall, C. M., Oppenheimer, S. J., Tyler-Smith, C., Durbin, R., Dortch, J., Manica, A., Schierup, M. H., Foley, R. A., Lahr, M. M., Bowern, C., Wall, J. D., Mailund, T., Stoneking, M., Nielsen, Rasmus, Sandhu, M. S., Excoffier, L., Lambert, D. M. & Willerslev, Eske, 2016, In: Nature. 538, 7624, p. 207-214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A hidden Markov model approach for determining expression from genomic tiling micro arrays

    Terkelsen, K. M., Gardner, P. P., Arctander, P. & Krogh, Anders, 2006, In: BMC Bioinformatics. 7, 239

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    A high-resolution map of human evolutionary constraint using 29 mammals

    Lindblad-Toh, K., Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Jordan, G., Mauceli, E., Ward, L. D., Lowe, C. B., Holloway, A. K., Clamp, M., Gnerre, S., Moltke, Ida, Wen, J. & Pedersen, J. S., 27 Oct 2011, In: Nature. 478, 7370, p. 476-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A kinetic model explains why shorter and less affine enzyme-recruiting oligonucleotides can be more potent

    Pedersen, L., Hagedorn, P. H., Lindholm, M. W. & Lindow, M., 2014, In: Molecular Therapy - Nucleic Acids. 3, 8 p., e149.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder

    Nøhr, A. K., Lindow, M., Forsingdal, A., Demharter, S., Nielsen, T., Buller, R., Moltke, Ida, Vitezic, M. & Albrechtsen, Anders, 2021, In: Neuropsychopharmacology. 46, 7, p. 1324-1332 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data

    Moreno-Mayar, J. V., Korneliussen, Thorfinn Sand, Dalal, J., Renaud, Gabriel, Albrechtsen, Anders, Nielsen, Rasmus & Malaspinas, A., 2020, In: Bioinformatics. 36, 3, p. 828-841 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    A long-standing Pleistocene refugium in southern Africa and a mosaic of refugia in East Africa: insights from mtDNA and the common eland antelope

    Lorenzen, Eline, Masembe, C., Arctander, P. & Siegismund, Hans Redlef, 2010, In: Journal of Biogeography. 37, 3, p. 571-581 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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