Computational and RNA Biology

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  1. 2023
  2. Published

    Convergent molecular evolution of thermogenesis and circadian rhythm in Arctic ruminants

    Li, M., Li, X., Wu, Z., Zhang, G., Wang, N., Dou, M., Liu, S., Yang, C., Meng, G., Sun, H., Hvilsom, C., Xie, G., Li, Y., Li, Z. H., Wang, W., Jiang, Y., Heller, Rasmus & Wang, Y., 2023, In: Proceedings of the Royal Society B: Biological Sciences. 290, 1999, 10 p., 20230538.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness

    Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    DNA metabarcoding illuminates the contribution of small and very small prey taxa to the diet of lions

    Groen, K., Beekenkamp, S., de Iongh, H. H., Lesilau, F., Chege, M., Narisha, L., Veldhuis, M., Bertola, Laura, van Bodegom, P. M. & Trimbos, K. B., 2023, In: Environmental DNA. 5, 6, p. 1321-1331 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Deciphering regulatory mechanisms underlying gene co-activity

    van Duin, Lucas, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 131 p.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Deep integrative models for large-scale human genomics

    Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load

    INSIGHT START Study Group, I. S. S. G., 2023, In: PLOS Computational Biology. 19, 1, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    DeepPeptide predicts cleaved peptides in proteins using conditional random fields

    Teufel, Felix Georg, Refsgaard, J. C., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Bioinformatics (Oxford, England). 39, 10, 6 p., btad616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Deorphanizing Peptides Using Structure Prediction

    Teufel, Felix Georg, Refsgaard, J. C., Kasimova, M. A., Deibler, K., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Journal of Chemical Information and Modeling. 63, 9, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    DermX: An end-to-end framework for explainable automated dermatological diagnosis

    Jalaboi, R., Faye, F., Orbes-Arteaga, M., Jørgensen, D., Winther, Ole & Galimzianova, A., 2023, In: Medical Image Analysis. 83, 12 p., 102647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Detecting host responses to microbial stimulation using primary epithelial organoids

    Lange, Jette Bornholdt, Müller, C. V., Nielsen, M. J., Strickertsson, J., Rago, D., Chen, Y., Maciag, Grzegorz Jerzy, Skov, Jonathan, Wellejus, A., Schweiger, P. J., Hansen, Stine Lind, Broholm, C., Gögenur, Ismail, Maimets, Martti, Sloth, S., Hendel, J., Baker, A., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Gut Microbes. 15, 2, 16 p., 2281012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DoxoDB: A Database for the Expression Analysis of Doxorubicin-Induced lncRNA Genes

    Distefano, R., Ilieva, M., Madsen, J. H., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 4, 24 p., 39.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Editorial: Long-read sequencing—Pitfalls, benefits and success stories

    Wohlers, I., Garg, S. & Hehir-Kwa, J. Y., 2023, In: Frontiers in Genetics. 13, 3 p., 1114542.

    Research output: Contribution to journal › Editorial › Research › peer-review

  14. Published

    Estimating admixture pedigrees of recent hybrids without a contiguous reference genome

    Garcia Erill, Genís, Hanghøj, Kristian Ebbesen, Heller, Rasmus, Wiuf, Carsten & Albrechtsen, Anders, 2023, In: Molecular Ecology Resources. 23, 7, p. 1604-1619 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Evaluation of population structure inferred by principal component analysis or the admixture model

    Van Waaij, J., Li, Song, Garcia Erill, Genís, Albrechtsen, Anders & Wiuf, Carsten, 2023, In: Genetics. 225, 2, 14 p., iyad157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Evidence for early domestic yak, taurine cattle, and their hybrids on the Tibetan Plateau

    Chen, N., Zhang, Z., Hou, J., Chen, J., Gao, X., Tang, L., Wangdue, S., Zhang, X., Sinding, Mikkel Holger Strander, Liu, X., Han, J., Lü, H., Lei, C., Marshall, F. & Liu, X., 2023, In: Science Advances. 9, 50, 13 p., eadi6857.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Explainable Image Quality Assessments in Teledermatological Photography

    Jalaboi, R., Winther, Ole & Galimzianova, A., 2023, In: Telemedicine and e-Health. 29, 9, p. 1342-1348 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exploring antidepressant treatment response using biological and clinical measurements

    Nøhr, A. K., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 125 p.

    Research output: Book/Report › Ph.D. thesis › Research

  19. Published

    Fast and accurate out-of-core PCA framework for large scale biobank data

    Li, Z., Meisner, Jonas & Albrechtsen, Anders, 2023, In: Genome Research. 33, 9, p. 1599-1608 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Functions of m6A-YTH modules in plants: Lessons from high-throughput sequencing analyses

    Porcelli, C., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 178 p.

    Research output: Book/Report › Ph.D. thesis › Research

  21. Published

    Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives

    Senftleber, N. K., Ramne, Stina, Moltke, Ida, Jørgensen, M. E., Albrechtsen, Anders, Hansen, Torben & Lepola, Mette Andersen, 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Genetics as a novel tool in mining impact assessment and biomonitoring of critically endangered western chimpanzees in the Nimba Mountains, Guinea

    Koops, K., Humle, T., Frandsen, P., Fitzgerald, M., D'Auvergne, L., Jackson, H. A., Børsting, Claus, Siegismund, Hans Redlef, Soumah, A. G. & Hvilsom, C., 2023, In: Conservation Science and Practice. 5, 4, 17 p., e12898.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Genomic diversity and differentiation between island and mainland populations of white-tailed eagles (Haliaeetus albicilla)

    Hansen, C. C. R., Láruson, Á. J., Rasmussen, Jacob Agerbo, Ballesteros, J. A. C., Sinding, Mikkel Holger Strander, Hallgrimsson, G. T., von Schmalensee, M., Stefansson, R. A., Skarphédinsson, K. H., Labansen, A. L., Leivits, M., Sonne, C., Dietz, R., Skelmose, K., Boertmann, D., Eulaers, I., Martin, M. D., Helgason, A. S., Gilbert, M Thomas P & Pálsson, S., 2023, In: Molecular Ecology. 32, 8, p. 1925-1942 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genomics of adaptive evolution in the woolly mammoth

    Díez-del-Molino, D., Dehasque, M., Chacón-Duque, J. C., Chrzanová Pecnerová, Patrícia, Tikhonov, A., Protopopov, A., Plotnikov, V., Kanellidou, F., Nikolskiy, P., Mortensen, P., Danilov, G. K., Vartanyan, S., Gilbert, M Thomas P, Lister, A. M., Heintzman, P. D., van der Valk, T. & Dalén, L., 2023, In: Current Biology. 33, 9, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Global determinants of insect mitochondrial genetic diversity

    French, C. M., Bertola, Laura, Carnaval, A. C., Economo, E. P., Kass, J. M., Lohman, D. J., Marske, K. A., Meier, R., Overcast, I., Rominger, A. J., Staniczenko, P. P. A. & Hickerson, M. J., 2023, In: Nature Communications. 14, 1, 15 p., 5276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Global dispersal and adaptive evolution of domestic cattle: a genomic perspective

    Xia, X., Qu, K., Wang, Y., Sinding, Mikkel Holger Strander, Wang, F., Hanif, Q., Ahmed, Z., Lenstra, J. A., Han, J., Lei, C. & Chen, N., 2023, In: Stress Biology. 3, 1, 13 p., 8.

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing

    Chen, N., Xia, X., Hanif, Q., Zhang, F., Dang, R., Huang, B., Lyu, Y., Luo, X., Zhang, H., Yan, H., Wang, S., Wang, F., Chen, J., Guan, X., Liu, Y., Li, S., Jin, L., Wang, P., Sun, L., Zhang, J. & 37 others, Liu, J., Qu, K., Cao, Y., Sun, J., Liao, Y., Xiao, Z., Cai, M., Mu, L., Siddiki, A. Z., Asif, M., Mansoor, S., Babar, M. E., Hussain, T., Silva, G. L. L. P., Gorkhali, N. A., Terefe, E., Belay, G., Tijjani, A., Zegeye, T., Gebre, M. G., Ma, Y., Wang, Y., Huang, Y., Lan, X., Chen, H., Migliore, N. R., Colombo, G., Semino, O., Achilli, A., Sinding, Mikkel Holger Strander, Lenstra, J. A., Cheng, H., Lu, W., Hanotte, O., Han, J., Jiang, Y. & Lei, C., 2023, In: Nature Communications. 14, 1, 13 p., 7803.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Graph neural network interatomic potential ensembles with calibrated aleatoric and epistemic uncertainty on energy and forces

    Busk, J., Schmidt, M. N., Winther, Ole, Vegge, T. & Jørgensen, P. B., 2023, In: Physical Chemistry Chemical Physics. 25, p. 25828-25837 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    GraphPart: homology partitioning for biological sequence analysis

    Teufel, Felix Georg, Gíslason, M. H., Almagro Armenteros, J. J., Johansen, A. R., Winther, Ole & Nielsen, H., 2023, In: NAR Genomics and Bioinformatics. 5, 4, 9 p., lqad088.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

    Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing

    Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña, E., Thuesen, Anne Cathrine Baun, Hussain, M., Stæger, Frederik Filip Vinggaard, Gjesing, A. P., Albrechtsen, Anders & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 13 p., 1128850.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Interpreting the molecular mechanisms of disease variants in human transmembrane proteins

    Tiemann, Johanna Katarina Sofie, Zschach, Henrike, Lindorff-Larsen, Kresten & Stein, Amelie, 2023, In: Biophysical Journal. 122, 11, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Limited historical admixture between European wildcats and domestic cats

    Jamieson, A., Carmagnini, A., Howard-McCombe, J., Doherty, S., Hirons, A., Dimopoulos, E., Lin, A. T., Allen, R., Anderson-Whymark, H., Barnett, R., Batey, C., Beglane, F., Bowden, W., Bratten, J., De Cupere, B., Drew, E., Foley, N. M., Fowler, T., Fox, A., Geigl, E-M. & 35 others, Gotfredsen, Anne Birgitte, Grange, T., Griffiths, D., Groß, D., Haruda, A., Hjermind, J., Knapp, Z., Lebrasseur, O., Librado, P., Lyons, L. A., Mainland, I., McDonnell, C., Muñoz-Fuentes, V., Nowak, C., O'Connor, T., Peters, J., Russo, I. M., Ryan, H., Sheridan, A., Sinding, Mikkel Holger Strander, Skoglund, P., Swali, P., Symmons, R., Thomas, G., Jensen, Theis Zetner Trolle, Kitchener, A. C., Senn, H., Lawson, D., Driscoll, C., Murphy, W. J., Beaumont, M., Ottoni, C., Sykes, N., Larson, G. & Frantz, L., 2023, In: Current Biology. 33, 21, p. 4751-4760.e14

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Long divergent haplotypes introgressed from wild sheep are associated with distinct morphological and adaptive characteristics in domestic sheep

    Cheng, H., Zhang, Z., Wen, J., Lenstra, J. A., Heller, Rasmus, Cai, Y., Guo, Y., Li, M., Li, R., Li, W., He, S., Wang, J., Shao, J., Song, Y., Zhang, L., Billah, M., Wang, X., Liu, M. & Jiang, Y., 2023, In: PLOS Genetics. 19, 2, 27 p., e1010615.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Mind the gap

    Larsen-Ledet, Sven & Stein, Amelie, 2023, In: Structure. 31, 6, p. 641-643 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  37. Published

    Molecular Representations in Machine-Learning-Based Prediction of PK Parameters for Insulin Analogs

    Einarson, K. A., Bendtsen, K. M., Li, K., Thomsen, M., Kristensen, N. R., Winther, Ole, Fulle, S., Clemmensen, L. & Refsgaard, H. H. F., 2023, In: ACS Omega. 8, 26, p. 23566-23578 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Multiple paths toward repeated phenotypic evolution in the spiny-leg adaptive radiation (Tetragnatha; Hawai'i)

    Cerca, J., Cotoras, D. D., Santander, Cindy, Bieker, V. C., Hutchins, L., Morin-Lagos, J., Prada, C. F., Kennedy, S., Krehenwinkel, H., Rominger, A. J., Meier, J., Dimitrov, D., Struck, T. H. & Gillespie, R. G., 2023, In: Molecular Ecology. 32, 18, p. 4971-4985 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    On the origin of regulatory elements: Computational analyses of transposable elements in pluripotency and development

    Bakoulis, Stylianos, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 135 p.

    Research output: Book/Report › Ph.D. thesis › Research

  40. Published

    Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus

    Martínez-Pérez, M., Aparicio, F., Arribas Hernandez, Laura, Tankmar, Mathias Due, Rennie, Sarah, von Bülow, Sören, Lindorff-Larsen, Kresten, Brodersen, Peter & Pallas, V., 2023, In: EMBO Journal. 42, 18, 17 p., e113378.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain

    Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Possible signs of recovery of the nearly extirpated Spitsbergen bowhead whales: calves observed in east Greenland

    Tervo, O. M., Louis, Marie Georgette Yolande J, Sinding, Mikkel Holger Strander, Heide-Jørgensen, M. P. & Hansen, R. G., 2023, In: Polar Research. 42, 4 p., 8809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Potential usages of A-to-I RNA editing patterns as diagnostic biomarkers

    Rodriguez Morales, D., Ilieva, M., Rennie, Sarah & Uchida, S., 2023, In: American journal of physiology. Cell physiology. 324, 4, p. C837-C842 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Probabilistic modelling in genomics

    Rasmussen, Malthe Sebro, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 158 p.

    Research output: Book/Report › Ph.D. thesis › Research

  45. Published

    Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia

    Bech, J. M., Terkelsen, Thilde Bagger, Bartels, Annette Snejbjerg, Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G. I., Fang, X., Mann, Matthias & Moreira, José, 2023, In: Gastroenterology. 165, 1, p. 121-132.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets

    He, Yue, Døssing, Kristina Benedikte V, Sloth, Ane Beth, He, Xuening, Rossing, M. & Kjær, Andreas, 2023, In: Cancers. 15, 5, 16 p., 1557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    RNA trafficking and subcellular localization—a review of mechanisms, experimental and predictive methodologies

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2023, In: Briefings in Bioinformatics. 24, 5, 14 p., bbad249.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Rapid protein stability prediction using deep learning representations

    Blaabjerg, Lasse Møller, Kassem, M. M., Good, L. L., Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer Enøe, Boomsma, Wouter, Stein, Amelie & Lindorff-Larsen, Kresten, 2023, In: eLife. 12, 19 p., e82593.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Redefining the Evolutionary History of the Rock Dove, Columba livia, Using Whole Genome Sequences

    Hernández Alonso, Germán, Ramos Madrigal, Jazmin, van Grouw, H., Ciucani, Marta Maria, Cavill, Emily Louisa, Sinding, Mikkel Holger Strander, Gopalakrishnan, Shyam, Antunes Pacheco, George & Gilbert, M Thomas P, 2023, In: Molecular Biology and Evolution. 40, 11, 17 p., msad243.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Regulation of plant immunity via small RNA-mediated control of NLR expression

    López Márquez, Diego, Del-Espino, Á., Ruiz-Albert, J., Bejarano, E. R., Brodersen, Peter & Beuzón, C. R., 2023, In: Journal of Experimental Botany. 74, 19, p. 6052-6068 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity

    Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Riveiro, Alba, Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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