- 2011
- Published
maxAlike: maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences
Menzel, K. P., Stadler, P. F. & Gorodkin, Jan, 2011, In: Bioinformatics. 27, 3, p. 317-325 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miR-449 inhibits cell proliferation and is down-regulated in gastric cancer
Bou Kheir, T., Futoma-Kazmierczak, E., Jacobsen, A., Krogh, Anders, Bardram, L., Hother, C., Grønbæk, Kirsten, Federspiel, B., Lund, Anders H. & Friis-Hansen, Lennart Jan, 2011, In: Molecular Cancer. 10, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
microRNA-101 is a potent inhibitor of autophagy
Frankel, Lisa, Wen, J., Lees, M., Høyer-Hansen, M., Farkas, T., Krogh, Anders, Jäättelä, M. & Lund, Anders H., 2011, In: E M B O Journal. 30, p. 4628-4641 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Differential expression of cellular microRNAs in HPV-11 transfected cells. An analysis by three different array platforms and qRT-PCR
Dreher, A., Rossing, M., Kaczkowski, B., Nielsen, Finn Cilius & Norrild, B., 17 Dec 2010, In: Biochemical and Biophysical Research Communications. 403, 3-4, p. 357-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary analysis of foot-and-mouth disease virus serotype SAT 1 isolates from East Africa suggests two independent introductions from southern Africa
Sangula, A. K., Belsham, G., Muwanika, V. B., Heller, Rasmus, Balinda, S. N., Masembe, C. & Siegismund, Hans Redlef, 30 Nov 2010, In: BMC Evolutionary Biology. 10, 1, p. 371Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diversity and transboundary mobility of serotype O foot-and-mouth disease virus in East Africa: implications for vaccination policies
Balinda, S., Sangula, A. K., Heller, Rasmus, Muwanika, V. B., Belsham, G., Masembe, C. & Siegismund, Hans Redlef, 1 Oct 2010, In: Infection, Genetics and Evolution. 10, 7, p. 1058-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long- and short-term selective forces on malaria parasite genomes
Nygaard, S., Braunstein, A., Malsen, G., Van Dongen, S., Gardner, P. P., Krogh, Anders, Otto, T. D., Pain, A., Berriman, M., McAuliffe, J., Dermitzakis, E. T. & Jeffares, D. C., 1 Sep 2010, In: P L o S Genetics. 6, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda
Balinda, S., Belsham, G., Masembe, C., Sangula, A. K., Siegismund, Hans Redlef & Muwanika, V. B., 1 Aug 2010, In: Epidemiology and Infection. 138, 8, p. 1204-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signatures of RNA binding proteins globally coupled to effective microRNA target sites
Jacobsen, A., Wen, J., Marks, D. S. & Krogh, Anders, 1 Aug 2010, In: Genome Research. 20, 8, p. 1010-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequencing of 50 human exomes reveals adaptation to high altitude
Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, , 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia
Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, , 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Harder, T., Boomsma, Wouter, Paluszewski, M., Frellsen, J., Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 306Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models
Stovgaard, K., Andreetta, C., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 429Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-methylcholanthrene induces differential recruitment of aryl hydrocarbon receptor to human promoters
Pansoy, A., Ahmed, S., Valen, E., Sandelin, Albin Gustav & Matthews, J., 2010, In: Toxicological Sciences. 117, 1, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A long-standing Pleistocene refugium in southern Africa and a mosaic of refugia in East Africa: insights from mtDNA and the common eland antelope
Lorenzen, Eline, Masembe, C., Arctander, P. & Siegismund, Hans Redlef, 2010, In: Journal of Biogeography. 37, 3, p. 571-581 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A simple procedure for routine RNA extraction and miRNA array analyses from a single thyroid in vivo fine needle aspirate
Rossing, M., Kaczkowski, B., Futoma-Kazmierczak, E., Glud, M., Klausen, M., Faber, Jens, Nygaard, Birte, Kiss, K., Sørensen, C. H., Nielsen, Finn Cilius, Bennedbæk, F. N. & Friis-Hansen, Lennart Jan, 2010, In: Scandinavian Journal of Clinical & Laboratory Investigation. 70, 8, p. 529-534 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli
Hove-Jensen, B., Rosenkrantz, T. J., Zechel, D. L. & Willemoës, Martin, 2010, In: Journal of Bacteriology. 192, 1, p. 370-374Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003)
Ayebazibwe, C., Mwiine, F. N., Balinda, S. N., Tjørnehøj, K., Masembe, C., Muwanika, V. B., Okurut, A. R. A., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: Transboundary and Emerging Diseases. 57, 4, p. 286-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioinformatical approaches to RNA structure prediction & Sequencing of an ancient human genome
Lindgreen, S., 2010, Biologisk Institut: Museum Tusculanum. 111 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Can small wildlife conservancies maintain genetically stable populations of large mammals? Evidence for increased genetic drift in geographically restricted populations of Cape buffalo in East Africa
Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2010, In: Molecular Ecology. 19, 7, p. 1324-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control
Sangula, A. K., Belsham, G. J., Muwanika, V. B., Heller, Rasmus, Balinda, S. N. & Siegismund, Hans Redlef, 2010, In: Archives of Virology. 155, 10, p. 1625-1630Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system
Rapin, N. P. J., Lund, O., Bernaschi, M. & Castiglione, F., 2010, In: PloS one. 5, 4, p. e9862Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deciphering Transcriptional Regulation: Computational Approaches
Valen, E., 2010, Museum Tusculanum. 97 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Design of association studies with pooled or un-pooled next-generation sequencing data
Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus
Motti, D., Le Duigou, C., Eugène, E., Chemaly, N., Wittner, L., Lazarevic, D., Krmac, H., Marstrand, T., Valen, E., Sanges, R., Stupka, E., Sandelin, Albin Gustav, Cherubini, E., Gustincich, S. & Miles, R., 2010, In: European Journal of Neuroscience. 32, 8, p. 1364-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic diversity among ancient Nordic populations
Melchior, L. C., Lynnerup, Niels, Siegismund, Hans Redlef, Kivisild, T. & Dissing, J., 2010, In: PLOS ONE. 5, 7, 9 p., e11898.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation of inbreeding depression among floral and fitness traits in Silene nutans
Thiele, J., Hansen, T. M., Siegismund, Hans Redlef & Hauser, T. P., 2010, In: Heredity. 104, 1, p. 52-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a novel locus for a USH3 like syndrome combined with congenital cataract
Dad, S., Østergaard, Elsebet, Thykjær, T., Albrechtsen, Anders, Ravn, K. J. T., Rosenberg, T. & Møller, L. B., 2010, In: Clinical Genetics. 78, 4, p. 388-397 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA-145 targets YES and STAT1 in colon cancer cells
Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs and potential target interactions in psoriasis
Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mocapy++ - a toolkit for inference and learning in dynamic Bayesian networks
Paluszewski, M. & Hamelryck, Thomas Wim, 2010, In: BMC Bioinformatics. 11, Suppl 1, 6 p., 126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular signatures of thyroid follicular neoplasia
Helweg-Larsen, R. B., Rossing, M., Henao Giraldo, R., Yamamoto, Y., Krogdahl, A., Godballe, C., Winther, Ole, Kiss, K., Christensen, L. H., Høgdall, Estrid Vilma Solyom, Bennedbæk, F. N. & Nielsen, Finn Cilius, 2010, In: Endocrine - Related Cancer. 17, 3, p. 691-708 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multivariate Hawkes process models of the occurrence of regulatory elements
Carstensen, L., Sandelin, Albin Gustav, Winther, Ole & Hansen, Niels Richard, 2010, In: BMC Bioinformatics. 11, p. 456Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patterns, risk factors and characteristics of reported and perceived foot-and-mouth disease (FMD) in Uganda
Ayebazibwe, C., Tjørnehøj, K., Mwiine, F. N., Muwanika, V. B., Ademun Okurut, A. R., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: Tropical Animal Health and Production. 42, 7, p. 1547-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phylogenetic analyses of the polyprotein coding sequences of serotype O foot-and-mouth disease viruses in East Africa: evidence for interserotypic recombination
Balinda, S. N., Siegismund, Hans Redlef, Muwanika, V. B., Sangula, A. K., Masembe, C., Ayebazibwe, C., Normann, P. & Belsham, G. J., 2010, In: Virology Journal. 7, p. 199Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive selection on apoptosis related genes
Rodrigues da Fonseca, Rute Andreia, Kosiol, C., Vinař, T., Siepel, A. & Nielsen, Rasmus, 2010, In: FEBS Letters. 584, 3, p. 469-476 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Potentials of mean force for protein structure prediction vindicated, formalized and generalized
Hamelryck, Thomas Wim, Borg, M., Paluszewski, M., Paulsen, J., Frellsen, J., Andreetta, C., Boomsma, Wouter, Bottaro, S. & Ferkinghoff-Borg, J., 2010, In: PLoS ONE. 5, 11, 11 p., e13714.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein structure prediction using bee colony optimization metaheuristic
Fonseca, R., Paluszewski, M. & Winter, Pawel, 2010, In: Journal of Mathematical Modelling and Algorithms. 9, 2, p. 181-194 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, , 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence reconstruction and improved non-coding RNA homology search
Menzel, K. P., 2010, Department of Basic Animal and Veterinary Sciences, University of Copenhagen. 172 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
The role of African buffalos (syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda
Ayebazibwe, C., Mwiine, F. N., Tjørnehøj, K., Balinda, S. N., Muwanika, V. B., Okurut, A. R. A., Belsham, G. J., Normann, P., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: BMC Veterinary Research. 6, 13 p., 54.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sequence and de novo assembly of the giant panda genome
Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., Zhang, Z., Zhang, Y., Wang, W., Li, J., Wei, F., Li, H., Jian, M., Li, J., Zhang, Z., Nielsen, R. & 103 others, , 2010, In: Nature. 463, 7279, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury
Ryge, J., Winther, Ole, Wienecke, Jacob, Sandelin, Albin Gustav, Westerdahl, A., Hultborn, Hans & Kiehn, O., 2010, In: BMC Genomics. 11, 1, p. 365 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRMaid: a unified programming interface for microRNA data resources
Jacobsen, A., Krogh, Anders, Kauppinen, S. & Lindow, M., 2010, In: BMC Bioinformatics. 11, Suppl 1, p. 29Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
MicroRNA expression analysis by LNA enhanced microarrays
Søkilde, R., Kaczkowski, B., Barken, K. B., Mouritzen, P., Møller, Søren & Litman, Thomas, 1 Oct 2009, MicroRNA Profiling in Cancer: A Bioinformatics Perspective. Pan Stanford Publishing Pte. Ltd., p. 23-46 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families
Hansen, Thomas van Overeem, Jønson, L., Albrechtsen, Anders, Andersen, M. K., Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, May 2009, In: Breast Cancer Research and Treatment. 115, 2, p. 315-323 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common Greenlandic Inuit BRCA1 RING domain founder mutation
Hansen, T. V. O., Ejlertsen, Bent Laursen, Albrechtsen, Anders, Bergsten, E., Bjerregaard, P., Hansen, T., Myrhoj, T., Nielsen, P. B., Timmermans-Wielenga, V., Andersen, M. K., Jonson, L. & Nielsen, F. C., 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 69-76 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A fluorescent substrate for carbon-phosphorus lyase: towards the pathway for organophosphonate metabolism in bacteria
He, S., Lou, Y., Hove-Jensen, B. & Zechel, D. L., 2009, In: Bioorganic & Medicinal Chemistry Letters. 19, 20, p. 5954-5957Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch
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Genetic diversity of lion populations in Kenya: Evaluating past management practices and recommendations for future conservation actions
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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
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