- Published
Integrating convolution and self-attention improves language model of human genome for interpreting non-coding regions at base-resolution
YANG, Meng, Huang, L., Huang, H., Tang, H., Zhang, N., Yang, H., Wu, J. & Mu, F., 2022, In: Nucleic Acids Research. 50, 14, 19 p., e81.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TrustGWAS: A full-process workflow for encrypted GWAS using multi-key homomorphic encryption and pseudorandom number perturbation
YANG, Meng, Zhang, C., Wang, X., Liu, X., Li, S., Huang, J., Feng, Z., Sun, X., Chen, F., Yang, S., Ni, M., Li, L., Cao, Y. & Mu, F., 2022, In: Cell Systems. 13, 9, p. 752-767.e6 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contrastive learning enables rapid mapping to multimodal single-cell atlas of multimillion scale
YANG, Meng, Yang, Y., Xie, C., Ni, M., Liu, J., Yang, H., Mu, F. & Wang, J., 2022, In: Nature Machine Intelligence. 4, 8, p. 696-709 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo
Yang, M., Woolfenden, H. C., Zhang, Y., Fang, X., Liu, Q., Vigh, Maria Louisa, Cheema, J., Yang, X., Norris, M., Yu, S., Carbonell, A., Brodersen, Peter, Wang, J. & Ding, Y., 2020, In: Nucleic Acids Research. 48, 15, p. 8767-8781 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In defense of statistical methods for detecting positive selection
Yang, Z., Nielsen, Rasmus & Goldman, N., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 36, p. E95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival
Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequencing of 50 human exomes reveals adaptation to high altitude
Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, , 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The frequent evolutionary birth and death of functional promoters in mouse and human
Young, R. S., Hayashizaki, Y., Andersson, Robin, Sandelin, Albin Gustav, Kawaji, H., Itoh, M., Lassmann, T., Carninci, P., Bickmore, W. A., Forrest, A. R. & Taylor, M. S., 2015, In: Genome Research. 25, p. 1546-1557 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, , 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptomic landscape of the sheep rumen provides insights into physiological programming development and adaptation of digestive strategies
Yuan, Y., Sun, D., Qin, T., Mao, S., Zhu, W., Yin, Y., Huang, J., Heller, Rasmus, Li, Z., Liu, J. & Qiu, Q., 2022, In: Zoological research. 43, 4, p. 634-647 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical application of high-throughput sequencing technology in prenatal screening and diagnosis of birth defects
ZENG, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Unraveling the genetic basis of neurological diseases and thalassemia: the clinical utility of high throughput sequencing
ZHANG, W., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 117 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DivA: detection of non-homologous and very divergent regions in protein sequence alignments
Zepeda Mendoza, M. L., Nygaard, S. & Rodrigues da Fonseca, Rute Andreia, 2014, In: BMC Research Notes. 7, 806, 6 p., 806.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of the statistical power of neutrality tests based on comparative and population genetic data
Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two Novel α-Thalassemia Mutations CD 39 -C [Thr > Pro] and CD 109 ACC > CCC [Thr > Pro] Identified in Two Chinese Families: A Case Report
Zhang, W., Han, X., Deng, J., Zhou, R., Du, X., Wu, C. & Li, M., 2023, In: Hemoglobin. 47, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GMD: measuring the distance between histograms with applications on high-throughput sequencing reads
Zhao, X. & Sandelin, Albin Gustav, 2012, In: Bioinformatics. 28, 8, p. 1164-1165 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On gene regulation in eukaryotes: computational approaches to decipher transcriptional regulation at genetic and epigenetic level
Zhao, X., 2012, Department of Biology, Faculty of Science, University of Copenhagen. 170 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Systematic clustering of transcription start site landscapes
Zhao, X., Valen, E., Parker, B. J. & Sandelin, Albin Gustav, 2011, In: P L o S One. 6, 8, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations
Zhao, X., Qu, Kunli, Curci, B., Yang, H., Bolund, L., Lin, L. & Luo, Y., 2023, In: Biomolecules. 13, 5, 15 p., 870.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The origin of domestication genes in goats
Zheng, Z., Wang, X., Li, M., Li, Y., Yang, Z., Wang, X., Pan, X., Gong, M., Zhang, Y., Guo, Y., Wang, Y., Liu, J., Cai, Y., Chen, Q., Okpeku, M., Colli, L., Cai, D., Wang, K., Huang, S., Sonstegard, T. S. & 16 others, , 2020, In: Science Advances. 6, 21, eaaz5216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance characterization of PCR-free whole genome sequencing for clinical diagnosis
Zhou, G., Zhou, M., Zeng, F., Zhang, N., Sun, Y., Qiao, Z., Guo, X., Zhou, S., Yun, G., Xie, J., Wang, X., Liu, F., Fan, C., Wang, Y., Fang, Z., Tian, Z., Dai, W., Sun, J., Peng, Z. & Song, L., 2022, In: Medicine. 101, 10, 8 p., e28972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole Genome Sequencing in the Evaluation of Fetal Structural Anomalies: A Parallel Test with Chromosomal Microarray Plus Whole Exome Sequencing
Zhou, J., Yang, Z., Sun, J., Liu, L., Zhou, X., Liu, F., Xing, Y., Cui, S., Xiong, S., Liu, X., Yang, Y., Wei, X., Zou, G., Wang, Z., Wei, X., Wang, Y., Zhang, Y., Yan, S., Wu, F., Zeng, F. & 4 others, , 2021, In: Genes. 12, 3, 14 p., 376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs and potential target interactions in psoriasis
Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A draft genome sequence of the elusive giant squid, Architeuthis dux
da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, , 2020, In: GigaScience. 9, 1, 12 p., giz152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consequences of breed formation on patterns of genomic diversity and differentiation: the case of highly diverse peripheral Iberian cattle
Rodrigues da Fonseca, Rute Andreia, Urena, I., Afonso, S., Pires, A. E., Jørsboe, E., Chikhi, L. & Ginja, C., 2019, In: BMC Genomics. 20, p. 1-13 334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining methods for non-invasive fecal DNA enables whole genome and metagenomic analyses in wildlife biology
de Flamingh, A., Ishida, Y., Chrzanová Pecnerová, Patrícia, Vilchis, S., Siegismund, Hans Redlef, van Aarde, R. J., Malhi, R. S. & Roca, A. L., 2023, In: Frontiers in Genetics. 13, 14 p., 1021004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chimpanzee genomic diversity reveals ancient admixture with bonobos
de Manuel, M., Kuhlwilm, M., Frandsen, P., Sousa, V. C., Desai, T., Prado-Martinez, J., Hernandez-Rodriguez, J., Dupanloup, I., Lao, O., Hallast, P., Schmidt, J. M., Heredia-Genestar, J. M., Benazzo, A., Barbujani, G., Peter, B. M., Kuderna, L. F. K., Casals, F., Angedakin, S., Arandjelovic, M., Boesch, C. & 17 others, , 2016, In: Science. 354, 6311, p. 477-481 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated expression atlas of miRNAs and their promoters in human and mouse
de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J. & 31 others, , 21 Aug 2017, In: Nature Biotechnology. 35, 9, p. 872-878 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic insights into early maritime adaptations in Western Patagonia
jxb425, jxb425, Moreno Mayar, J. Víctor, Alfonso-Durruty, M., Morello, F., Vilar, M., Wells, S., Campos, P. & Willerslev, Eske, 2018, p. 64. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Transcription factor expression is the main determinant of variability in gene co-activity
van Duin, Lucas, Krautz, Robert, Rennie, Sarah & Andersson, Robin, 2023, In: Molecular Systems Biology. 19, 7, 17 p., e11392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deciphering regulatory mechanisms underlying gene co-activity
van Duin, Lucas, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 131 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Estimation of the covariance structure from SNP allele frequencies
van Waaij, J., Li, Z. & Wiuf, Carsten, 2022, In: Statistical Applications in Genetics and Molecular Biology. 21, 1, 20 p., 20220005.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of alkaline treatment on bacteriochlorophyll a, quinones, and energy transfer in chlorosomes from Chlorobium tepidum and Chlorobium phaeobacteroides
van Walree, C. A., Sakuragi, Y., Steensgaard, D. B., Bösinger, C. S., Frigaard, Niels-Ulrik, Cox, R. P., Holzwarth, A. R. & Miller, M., 1999, In: Photochemistry and Photobiology. 69, p. 322-328 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new class of genic nuclear RNA species in Arabidopsis
van Wonterghem, M., Thieffry, A., Boyd, M., Lange, Jette Bornholdt & Brodersen, Peter, 2018, In: FEBS Letters. 592, 4, p. 631-643 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-Coding RNAs in Arabidopsis: Discovery of Nuclear ncRNAs from Body Methylated Genes and of miRNA Pathway Inhibition by Conserved, Bacterial Virulence Factor
van Wonterghem, M., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 109 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Reduced chromatin accessibility correlates with resistance to Notch activation
van den Ameele, J., Krautz, Robert, Cheetham, S. W., Donovan, A. P. A., Llorà-Batlle, O., Yakob, R. & Brand, A. H., 2022, In: Nature Communications. 13, 1, 10 p., 2210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, T., Pečnerová, P., Díez-del-Molino, D., Bergström, A., Oppenheimer, J., Hartmann, S., Xenikoudakis, G., Thomas, J. A., Dehasque, M., Sağlıcan, E., Fidan, F. R., Barnes, I., Liu, S., Somel, M., Heintzman, P. D., Nikolskiy, P., Shapiro, B., Skoglund, P., Hofreiter, M., Lister, A. M. & 2 others, , 2021, In: Nature. 591, 7849, p. 265-269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome
van der Valk, T., Dehasque, M., Chacón-Duque, J. C., Oskolkov, N., Vartanyan, S., Heintzman, P. D., Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D. & Dalén, L., 2022, In: iScience. 25, 8, 11 p., 104826.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic insights into the conservation status of the world's last remaining Sumatran rhinoceros populations
von Seth, J., Dussex, N., Diez-del-Molino, D., van der Valk, T., Kutschera, V. E., Kierczak, M., Steiner, C. C., Liu, S., Gilbert, M. T. P., Sinding, M-H. S., Prost, S., Guschanski, K., Nathan, S. K. S. S., Brace, S., Chan, Y. L., Wheat, C. W., Skoglund, P., Ryder, O. A., Goossens, B., Gotherstrom, A. & 1 others, , 2021, In: Nature Communications. 12, 1, 11 p., 2393.Research output: Contribution to journal › Journal article › Research › peer-review
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