- 2022
- Published
SignalP 6.0 predicts all five types of signal peptides using protein language models
Teufel, Felix Georg, Almagro Armenteros, J. J., Johansen, A. R., Gíslason, M. H., Pihl, S. I., Tsirigos, Konstantinos, Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 2022, In: Nature Biotechnology. 40, p. 1023-1025Research output: Contribution to journal › Comment/debate › Research
- Published
PAMP-triggered genetic reprogramming involves widespread alternative transcription initiation and an immediate transcription factor wave
Thieffry, A., López Márquez, Diego, Lange, Jette Bornholdt, Gholami Malekroudi, M., Bressendorff, Simon, Barghetti, A., Sandelin, Albin Gustav & Brodersen, Peter, 2022, In: The Plant Cell. 34, 7, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepLoc 2.0: multi-label subcellular localization prediction using protein language models
Thumuluri, V., Almagro Armenteros, J. J., Johansen, A. R., Nielsen, H. & Winther, Ole, 2022, In: Nucleic Acids Research. 50, W1, p. W228-W234Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis
Vigh, Maria Louisa, Bressendorff, Simon, Thieffry, A., Arribas Hernandez, Laura & Brodersen, Peter, 2022, In: Nucleic Acids Research. 50, 3, p. 1396-1415 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms Underlying siRNA Amplification in Arabidopsis thaliana
Vigh, Maria Louisa, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 201 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes
Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, , 2022, In: BMC Medical Genomics. 15, 16 p., 124.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudoreplication in genomics-scale data sets
Waples, R. S., Waples, R. K. & Ward, E. J., 2022, In: Molecular Ecology Resources. 22, 2, p. 503-518 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological responses of narwhals to anthropogenic noise: A case study with seismic airguns and vessel traffic in the Arctic
Williams, T. M., Blackwell, S. B., Tervo, O., Garde, E., Sinding, Mikkel Holger Strander, Richter, B. & Heide-Jørgensen, M. P., 2022, In: Functional Ecology. 36, 9, p. 2251-2266 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational identification of signals predictive for nuclear RNA exosome degradation pathway targeting
Wu, M., Schmid, M., Jensen, T. H. & Sandelin, Albin Gustav, 2022, In: NAR Genomics and Bioinformatics. 4, 3, 18 p., lqac071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two novel truncating variants of the ASPM gene identified in a nonconsanguineous Chinese family associated with primary microcephaly
Xu, S., Zhang, W., Zhou, R., Huang, H., Chen, W., Xiang, W., Liu, L. & Song, J., 2022, In: Clinical Dysmorphology. 31, 1, p. 1-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contrastive learning enables rapid mapping to multimodal single-cell atlas of multimillion scale
YANG, Meng, Yang, Y., Xie, C., Ni, M., Liu, J., Yang, H., Mu, F. & Wang, J., 2022, In: Nature Machine Intelligence. 4, 8, p. 696-709 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating convolution and self-attention improves language model of human genome for interpreting non-coding regions at base-resolution
YANG, Meng, Huang, L., Huang, H., Tang, H., Zhang, N., Yang, H., Wu, J. & Mu, F., 2022, In: Nucleic Acids Research. 50, 14, 19 p., e81.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TrustGWAS: A full-process workflow for encrypted GWAS using multi-key homomorphic encryption and pseudorandom number perturbation
YANG, Meng, Zhang, C., Wang, X., Liu, X., Li, S., Huang, J., Feng, Z., Sun, X., Chen, F., Yang, S., Ni, M., Li, L., Cao, Y. & Mu, F., 2022, In: Cell Systems. 13, 9, p. 752-767.e6 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptomic landscape of the sheep rumen provides insights into physiological programming development and adaptation of digestive strategies
Yuan, Y., Sun, D., Qin, T., Mao, S., Zhu, W., Yin, Y., Huang, J., Heller, Rasmus, Li, Z., Liu, J. & Qiu, Q., 2022, In: Zoological research. 43, 4, p. 634-647 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical application of high-throughput sequencing technology in prenatal screening and diagnosis of birth defects
ZENG, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance characterization of PCR-free whole genome sequencing for clinical diagnosis
Zhou, G., Zhou, M., Zeng, F., Zhang, N., Sun, Y., Qiao, Z., Guo, X., Zhou, S., Yun, G., Xie, J., Wang, X., Liu, F., Fan, C., Wang, Y., Fang, Z., Tian, Z., Dai, W., Sun, J., Peng, Z. & Song, L., 2022, In: Medicine. 101, 10, 8 p., e28972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of the covariance structure from SNP allele frequencies
van Waaij, J., Li, Z. & Wiuf, Carsten, 2022, In: Statistical Applications in Genetics and Molecular Biology. 21, 1, 20 p., 20220005.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced chromatin accessibility correlates with resistance to Notch activation
van den Ameele, J., Krautz, Robert, Cheetham, S. W., Donovan, A. P. A., Llorà-Batlle, O., Yakob, R. & Brand, A. H., 2022, In: Nature Communications. 13, 1, 10 p., 2210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome
van der Valk, T., Dehasque, M., Chacón-Duque, J. C., Oskolkov, N., Vartanyan, S., Heintzman, P. D., Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D. & Dalén, L., 2022, In: iScience. 25, 8, 11 p., 104826.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Circulating Free Fatty Acid and Phospholipid Signature Predicts Early Rapid Kidney Function Decline in Patients With Type 1 Diabetes
Afshinnia, F., Rajendiran, T. M., He, C., Byun, J., Montemayor, D., Darshi, M., Tumova, J., Kim, J., Limonte, C. P., Miller, R. G., Costacou, T., Orchard, T. J., Ahluwalia, Tarun Veer Singh, Rossing, Peter, Snell-Bergeon, J. K., de Boer, I. H., Natarajan, L., Michailidis, G., Sharma, K. & Pennathur, S., 2021, In: Diabetes Care. 44, 9, p. 2098-2106 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2
Arribas Hernandez, Laura, Rennie, Sarah, Köster, T., Porcelli, C., Lewinski, M., Staiger, D., Andersson, Robin & Brodersen, Peter, 2021, In: eLife. 10, 33 p., e72375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation
Arribas Hernandez, Laura, Rennie, Sarah, Schon, M., Porcelli, C., Enugutti, B., Andersson, Robin, Nodine, M. D. & Brodersen, Peter, 2021, In: eLife. 10, 27 p., e72377.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bending during seedling emergence: Mechanochemical insight
Bai, B., 2021, In: Trends in Plant Science. 26, 9, p. 879-881 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Cardiovascular autonomic neuropathy and the impact on progression of diabetic kidney disease in type 1 diabetes
Bjerre-Christensen, T., Winther, S. A., Tofte, N., Theilade, S., Ahluwalia, Tarun Veer Singh, Lajer, M., Hansen, T. W., Rossing, Peter & Hansen, C. S., 2021, In: B M J Open Diabetes Research & Care. 9, 1, 9 p., e002289.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The endangered White Sands pupfish (Cyprinodon tularosa) genome reveals low diversity and heterogenous patterns of differentiation
Black, A. N., Willoughby, J. R., Brüniche-Olsen, Anna, Pierce, B. L. & DeWoody, J. A., 2021, In: Molecular Ecology Resources. 21, 7, p. 2520-2532 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Life-history traits and habitat availability shape genomic diversity in birds: implications for conservation
Brüniche-Olsen, Anna, Kellner, K. F., Belant, J. L. & DeWoody, J. A., 2021, In: Proceedings of the Royal Society B: Biological Sciences. 288, 1961, 9 p., 21001441.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome Analysis Identifies GATA3-AS1 as a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients
Contreras-Espinosa, L., Alcaraz, N., De La Rosa-Velázquez, I. A., Díaz-Chávez, J., Cabrera-Galeana, P., Rebollar-Vega, R., Reynoso-Noverón, N., Maldonado-Martínez, H. A., González-Barrios, R., Montiel-Manríquez, R., Bautista-Sánchez, D., Castro-Hernández, C., Alvarez-Gomez, R. M., Jiménez-Trejo, F., Tapia-Rodríguez, M., García-Gordillo, J. A., Pérez-Rosas, A., Bargallo-Rocha, E., Arriaga-Canon, C. & Herrera, L. A., 2021, In: Journal of Molecular Diagnostics. 23, 10, p. 1306-1323 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes
Dahlström, E. H., Saksi, J., Forsblom, C., Uglebjerg, N., Mars, N., Thorn, L. M., Harjutsalo, V., Rossing, Peter, Ahluwalia, Tarun Veer Singh, Lindsberg, P. J., Sandholm, N., Groop, P. H. & FinnDiane Study Group, F. S. G., 2021, In: Diabetes. 70, 10, p. 2391-2401 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining Bayesian age models and genetics to investigate population dynamics and extinction of the last mammoths in northern Siberia
Dehasque, M., Chrzanová Pecnerová, Patrícia, Muller, H., Tikhonov, A., Nikolskiy, P., Tsigankova, V. I., Danilov, G. K., Díez-del-Molino, D., Vartanyan, S., Dalén, L. & Lister, A. M., 2021, In: Quaternary Science Reviews. 259, 10 p., 106913.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AutoCNV: a semiautomatic CNV interpretation system based on the 2019 ACMG/ClinGen Technical Standards for CNVs
Fan, C., Wang, Z., Sun, Y., Sun, J., Liu, X., Kang, L., Xu, Y., Yang, M., Dai, W., Song, L., Wei, X., Xiang, J., Huang, H., Zhou, M., Zeng, F., Huang, L., Xu, Z. & Peng, Z., 2021, In: BMC Genomics. 22, 12 p., 721.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reducing the rate of psychiatric re-admissions in bipolar disorder using smartphones - The RADMIS trial
Faurholt-Jepsen, M., Lindbjerg Tønning, M., Fros, M., Martiny, Klaus, Tuxen, N., Rosenberg, N., Busk, J., Winther, Ole, Thaysen-Petersen, D., Aamund, K. A., Tolderlund, L., Bardram, J. E. & Kessing, Lars Vedel, 2021, In: Acta Psychiatrica Scandinavica. 143, 5, p. 453-465 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional Profiles Reveal Deregulation of Lipid Metabolism and Inflammatory Pathways in Neurons Exposed to Palmitic Acid
Flores-León, M., Alcaraz, N., Pérez-Domínguez, M., Torres-Arciga, K., Rebollar-Vega, R., De la Rosa-Velázquez, I. A., Arriaga-Canon, C., Herrera, L. A., Arias, C. & González-Barrios, R., 2021, In: Molecular Neurobiology. 58, 9, p. 4639-4651 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic impact of an Ebola outbreak on a wild gorilla population
Fontsere, C., Frandsen, P., Hernandez-Rodriguez, J., Niemann, Jonas, Scharff-Olsen, Camilla Hjorth, Vallet, D., Le Gouar, P., Ménard, N., Navarro, A., Siegismund, Hans Redlef, Hvilsom, C., Gilbert, M Thomas P, Kuhlwilm, M., Hughes, D. & Marques-Bonet, T., 2021, In: BMC Genomics. 22, 12 p., 735.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M., Rasmussen, M., Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C., Kinalis, S., Madsen, M., Yde, C., Rønn, O. L., Marvig, R., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, bioRxiv, 29 p.Research output: Working paper › Preprint › Research
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vicariance followed by secondary gene flow in a young gazelle species complex
Garcia Erill, Genís, Kjær, M. M., Albrechtsen, Anders, Siegismund, Hans Redlef & Heller, Rasmus, 2021, In: Molecular Ecology. 30, 2, p. 528-544Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational methods for chromosome-scale haplotype reconstruction
Garg, S., 2021, In: Genome Biology. 22, 24 p., 101.Research output: Contribution to journal › Review › Research › peer-review
- Published
Light-Dependent Translation Change of Arabidopsis psbA Correlates with RNA Structure Alterations at the Translation Initiation Region
Gawroński, P., Enroth, Christel Hougård, Kindgren, P., Marquardt, Sebastian, Karpiński, S., Leister, D., Jensen, Poul Erik, Vinther, Jeppe & Scharff, L. B., 2021, In: Cells. 10, 2, 22 p., 322.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bsgatlas: A unified bacillus subtilis genome and transcriptome annotation atlas with enhanced information access
Geissler, Adrian Sven, Anthon, Christian, Alkan, F., González-Tortuero, E., Poulsen, L. D., Kallehauge, T. B., Breüner, A., Seemann, Ernst Stefan, Vinther, Jeppe & Gorodkin, Jan, 2021, In: Microbial Genomics. 7, 2, 17 p., 000524.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the degradation pathway of a disease-linked aspartoacylase variant
Andersen, Sarah Gersing, Wang, Y., Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Bjørnkjær, Lene, Willemoës, Martin, Andréasson, C., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De novo whole-genome assembly and resequencing resources for the roan (Hippotragus equinus), an iconic African antelope
Gonçalves, M., Siegismund, Hans Redlef, Van Vuuren, B. J., Koepfli, K., Ferrand, N. & Godinho, R., 2021, In: G3: Genes, Genomes, Genetics. 11, 2, 9 p., jkab002.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary history of the roan antelope across its African range
Gonçalves, M., Siegismund, Hans Redlef, van Vuuren, B. J., Ferrand, N. & Godinho, R., 2021, In: Journal of Biogeography. 48, 11, p. 2812-2827 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Grapotte, M., Saraswat, M., Bessière, C., Menichelli, C., Ramilowski, J. A., Severin, J., Hayashizaki, Y., Itoh, M., Tagami, M., Murata, M., Kojima-Ishiyama, M., Noma, S., Noguchi, S., Kasukawa, T., Hasegawa, A., Suzuki, H., Nishiyori-Sueki, H., Frith, M. C., Abugessaisa, I., Aitken, S. & 31 others, , 2021, In: Nature Communications. 12, 18 p., 3297.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A reference-free approach to analyse RADseq data using standard next generation sequencing toolkits
Heller, Rasmus, Nursyifa, Casia, Garcia Erill, Genís, Salmona, J., Chikhi, L., Meisner, Jonas, Korneliussen, Thorfinn Sand & Albrechtsen, Anders, 2021, In: Molecular Ecology Resources. 21, 4, p. 1085-1097 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma
Holst, Camilla Bjørnbak, Christensen, I. J., Vitting-Seerup, K., Skjøth-Rasmussen, J., Hamerlik, P., Poulsen, H. S. & Johansen, Julia Sidenius, 1 Jan 2021, In: Neuro-Oncology Advances. 3, 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TrancriptomeReconstructoR: data-driven annotation of complex transcriptomes
Ivanov, M., Sandelin, Albin Gustav & Marquardt, Sebastian, 2021, In: BMC Bioinformatics. 22, 15 p., 290.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P. & 2,908 others, , 2021, In: Autophagy. 17, p. 1-382 382 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Benchmarking blockchain-based gene-drug interaction data sharing methods: A case study from the iDASH 2019 secure genome analysis competition blockchain track
Kuo, T., Bath, T., Ma, S., Pattengale, N., YANG, Meng, Cao, Y., Hudson, C. M., Kim, J., Post, K., Xiong, L. & Ohno-Machado, L., 2021, In: International Journal of Medical Informatics. 154, 8 p., 104559.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The LEAFY floral regulator displays pioneer transcription factor properties
Lai, X., Blanc-Mathieu, R., GrandVuillemin, L., Huang, Y., Stigliani, Arnaud, Lucas, J., Thévenon, E., Loue-Manifel, J., Turchi, L., Daher, H., Brun-Hernandez, E., Vachon, G., Latrasse, D., Benhamed, M., Dumas, R., Zubieta, C. & Parcy, F., 2021, In: Molecular Plant. 14, 5, p. 829-837 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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