Computational and RNA Biology

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  1. 2010
  2. Published

    Can small wildlife conservancies maintain genetically stable populations of large mammals? Evidence for increased genetic drift in geographically restricted populations of Cape buffalo in East Africa

    Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2010, In: Molecular Ecology. 19, 7, p. 1324-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control

    Sangula, A. K., Belsham, G. J., Muwanika, V. B., Heller, Rasmus, Balinda, S. N. & Siegismund, Hans Redlef, 2010, In: Archives of Virology. 155, 10, p. 1625-1630

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system

    Rapin, N. P. J., Lund, O., Bernaschi, M. & Castiglione, F., 2010, In: PloS one. 5, 4, p. e9862

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Deciphering Transcriptional Regulation: Computational Approaches

    Valen, E., 2010, Museum Tusculanum. 97 p.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Design of association studies with pooled or un-pooled next-generation sequencing data

    Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus

    Motti, D., Le Duigou, C., Eugène, E., Chemaly, N., Wittner, L., Lazarevic, D., Krmac, H., Marstrand, T., Valen, E., Sanges, R., Stupka, E., Sandelin, Albin Gustav, Cherubini, E., Gustincich, S. & Miles, R., 2010, In: European Journal of Neuroscience. 32, 8, p. 1364-79 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Genetic diversity among ancient Nordic populations

    Melchior, L. C., Lynnerup, Niels, Siegismund, Hans Redlef, Kivisild, T. & Dissing, J., 2010, In: PLOS ONE. 5, 7, 9 p., e11898.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Genetic variation of inbreeding depression among floral and fitness traits in Silene nutans

    Thiele, J., Hansen, T. M., Siegismund, Hans Redlef & Hauser, T. P., 2010, In: Heredity. 104, 1, p. 52-60 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Identification of a novel locus for a USH3 like syndrome combined with congenital cataract

    Dad, S., Østergaard, Elsebet, Thykjær, T., Albrechtsen, Anders, Ravn, K. J. T., Rosenberg, T. & Møller, L. B., 2010, In: Clinical Genetics. 78, 4, p. 388-397 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    MicroRNA-145 targets YES and STAT1 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    MicroRNAs and potential target interactions in psoriasis

    Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Mocapy++ - a toolkit for inference and learning in dynamic Bayesian networks

    Paluszewski, M. & Hamelryck, Thomas Wim, 2010, In: BMC Bioinformatics. 11, Suppl 1, 6 p., 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Molecular signatures of thyroid follicular neoplasia

    Helweg-Larsen, R. B., Rossing, M., Henao Giraldo, R., Yamamoto, Y., Krogdahl, A., Godballe, C., Winther, Ole, Kiss, K., Christensen, L. H., Høgdall, Estrid Vilma Solyom, Bennedbæk, F. N. & Nielsen, Finn Cilius, 2010, In: Endocrine - Related Cancer. 17, 3, p. 691-708 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Multivariate Hawkes process models of the occurrence of regulatory elements

    Carstensen, L., Sandelin, Albin Gustav, Winther, Ole & Hansen, Niels Richard, 2010, In: BMC Bioinformatics. 11, p. 456

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Natural selection and the distribution of identity-by-descent in the human genome

    Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Patterns, risk factors and characteristics of reported and perceived foot-and-mouth disease (FMD) in Uganda

    Ayebazibwe, C., Tjørnehøj, K., Mwiine, F. N., Muwanika, V. B., Ademun Okurut, A. R., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: Tropical Animal Health and Production. 42, 7, p. 1547-59 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Phylogenetic analyses of the polyprotein coding sequences of serotype O foot-and-mouth disease viruses in East Africa: evidence for interserotypic recombination

    Balinda, S. N., Siegismund, Hans Redlef, Muwanika, V. B., Sangula, A. K., Masembe, C., Ayebazibwe, C., Normann, P. & Belsham, G. J., 2010, In: Virology Journal. 7, p. 199

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Positive selection on apoptosis related genes

    Rodrigues da Fonseca, Rute Andreia, Kosiol, C., Vinař, T., Siepel, A. & Nielsen, Rasmus, 2010, In: FEBS Letters. 584, 3, p. 469-476 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Potentials of mean force for protein structure prediction vindicated, formalized and generalized

    Hamelryck, Thomas Wim, Borg, M., Paluszewski, M., Paulsen, J., Frellsen, J., Andreetta, C., Boomsma, Wouter, Bottaro, S. & Ferkinghoff-Borg, J., 2010, In: PLoS ONE. 5, 11, 11 p., e13714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Protein structure prediction using bee colony optimization metaheuristic

    Fonseca, R., Paluszewski, M. & Winter, Pawel, 2010, In: Journal of Mathematical Modelling and Algorithms. 9, 2, p. 181-194 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

    Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Sequence reconstruction and improved non-coding RNA homology search

    Menzel, K. P., 2010, Department of Basic Animal and Veterinary Sciences, University of Copenhagen. 172 p.

    Research output: Book/Report › Ph.D. thesis › Research

  24. Published

    The role of African buffalos (syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda

    Ayebazibwe, C., Mwiine, F. N., Tjørnehøj, K., Balinda, S. N., Muwanika, V. B., Okurut, A. R. A., Belsham, G. J., Normann, P., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: BMC Veterinary Research. 6, 13 p., 54.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The sequence and de novo assembly of the giant panda genome

    Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., Zhang, Z., Zhang, Y., Wang, W., Li, J., Wei, F., Li, H., Jian, M., Li, J., Zhang, Z., Nielsen, R. & 103 others, Li, D., Gu, W., Yang, Z., Xuan, Z., Ryder, O. A., Leung, F. C., Zhou, Y., Cao, J., Sun, X., Fu, Y., Fang, X., Guo, X., Wang, B., Hou, R., Shen, F., Mu, B., Ni, P., Lin, R., Qian, W., Wang, G., Yu, C., Nie, W., Wang, J., Wu, Z., Liang, H., Min, J., Wu, Q., Cheng, S., Ruan, J., Wang, M., Shi, Z., Wen, M., Liu, B., Ren, X., Zheng, H., Dong, D., Cook, K., Shan, G., Zhang, H., Kosiol, C., Xie, X., Lu, Z., Zheng, H., Li, Y., Steiner, C. C., Lam, T. T., Lin, S., Zhang, Q., Li, G., Tian, J., Gong, T., Liu, H., Zhang, D., Fang, L., Ye, C., Zhang, J., Hu, W., Xu, A., Ren, Y., Zhang, G., Bruford, M. W., Li, Q., Ma, L., Guo, Y., An, N., Hu, Y., Zheng, Y., Shi, Y., Li, Z., Liu, Q., Chen, Y., Zhao, J., Qu, N., Zhao, S., Tian, F., Wang, X., Wang, H., Xu, L., Liu, X., Vinar, T., Wang, Y., Lam, T., Yiu, S., Liu, S., Zhang, H., Li, D., Huang, Y., Wang, X., Yang, G., Jiang, Z., Wang, J., Qin, N., Li, L., Li, J., Bolund, L., Kristiansen, Karsten, Wong, G. K., Olson, M., Zhang, X., Li, S., Yang, H., Wang, J. & Wang, J., 2010, In: Nature. 463, 7279, p. 311-317 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury

    Ryge, J., Winther, Ole, Wienecke, Jacob, Sandelin, Albin Gustav, Westerdahl, A., Hultborn, Hans & Kiehn, O., 2010, In: BMC Genomics. 11, 1, p. 365 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    miRMaid: a unified programming interface for microRNA data resources

    Jacobsen, A., Krogh, Anders, Kauppinen, S. & Lindow, M., 2010, In: BMC Bioinformatics. 11, Suppl 1, p. 29

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Beyond rotamers: a generative, probabilistic model of side chains in proteins

    Harder, T., Boomsma, Wouter, Paluszewski, M., Frellsen, J., Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 306

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models

    Stovgaard, K., Andreetta, C., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 429

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Ancient human genome sequence of an extinct Palaeo-Eskimo

    Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, Bunce, M., Lorenzen, Eline, Binladen, J. K. M. A., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L. A. A., Kristiansen, Karsten, Bak, M., Tommerup, Niels, Bendixen, C., Pierre, T. L., Grønnow, B., Meldgaard, Morten, Andreasen, C., Fedorova, S. A., Osipova, L. P., Higham, T. F. G., Ramsey, C. B., Hansen, Thomas van Overeem, Nielsen, Finn Cilius, Crawford, M. H., Brunak, Søren, Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Krogh, Anders, Wang, J. & Willerslev, Eske, 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Sequencing of 50 human exomes reveals adaptation to high altitude

    Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, Shan, Y., Li, S., Yang, Q., Asan, G., Ni, P., Tian, G., Xu, J., Liu, X., Jiang, T., Wu, R., Zhou, G., Tang, M., Qin, J., Wang, T., Feng, S., Li, G., Huasang, G., Luosang, J., Wang, W., Chen, F., Wang, Y., Zheng, X., Li, Z., Bianba, Z., Yang, G., Wang, X., Tang, S., Gao, G., Yong, C., Luo, Z., Gusang, L., Cao, Z., Zhang, Q., Ouyang, W., Ren, X., Liang, H., Zheng, H., Huang, Y., Li, J., Bolund, L., Kristiansen, Karsten, Li, Y., Zhang, Y., Zhang, X., Li, R., Li, S., Yang, H., Nielsen, Rasmus, Wang, J. & Wang, J., 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda

    Balinda, S., Belsham, G., Masembe, C., Sangula, A. K., Siegismund, Hans Redlef & Muwanika, V. B., 1 Aug 2010, In: Epidemiology and Infection. 138, 8, p. 1204-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Signatures of RNA binding proteins globally coupled to effective microRNA target sites

    Jacobsen, A., Wen, J., Marks, D. S. & Krogh, Anders, 1 Aug 2010, In: Genome Research. 20, 8, p. 1010-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Long- and short-term selective forces on malaria parasite genomes

    Nygaard, S., Braunstein, A., Malsen, G., Van Dongen, S., Gardner, P. P., Krogh, Anders, Otto, T. D., Pain, A., Berriman, M., McAuliffe, J., Dermitzakis, E. T. & Jeffares, D. C., 1 Sep 2010, In: P L o S Genetics. 6, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Diversity and transboundary mobility of serotype O foot-and-mouth disease virus in East Africa: implications for vaccination policies

    Balinda, S., Sangula, A. K., Heller, Rasmus, Muwanika, V. B., Belsham, G., Masembe, C. & Siegismund, Hans Redlef, 1 Oct 2010, In: Infection, Genetics and Evolution. 10, 7, p. 1058-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Evolutionary analysis of foot-and-mouth disease virus serotype SAT 1 isolates from East Africa suggests two independent introductions from southern Africa

    Sangula, A. K., Belsham, G., Muwanika, V. B., Heller, Rasmus, Balinda, S. N., Masembe, C. & Siegismund, Hans Redlef, 30 Nov 2010, In: BMC Evolutionary Biology. 10, 1, p. 371

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Differential expression of cellular microRNAs in HPV-11 transfected cells. An analysis by three different array platforms and qRT-PCR

    Dreher, A., Rossing, M., Kaczkowski, B., Nielsen, Finn Cilius & Norrild, B., 17 Dec 2010, In: Biochemical and Biophysical Research Communications. 403, 3-4, p. 357-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2011
  40. Published

    A genome-wide scan in affected sib-pairs with idiopathic recurrent miscarriage suggests genetic linkage

    Kolte, A. M., Nielsen, Henriette Svarre, Moltke, Ida, Degn, B., Pedersen, B., Sunde, L., Nielsen, Finn Cilius & Christiansen, O. B., 2011, In: Molecular Human Reproduction. 17, 6, p. 379-385 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics

    Moltke, Ida, Albrechtsen, Anders, Hansen, Thomas van Overeem, Nielsen, Finn Cilius & Nielsen, Rasmus, 2011, In: Genome Research. 21, 7, p. 1168-80 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    A statistical view on the reference ratio method

    Mardia, K., Frellsen, J., Borg, M., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2011. 6 p.

    Research output: Contribution to conference › Paper › Research

  43. Published

    An Aboriginal Australian genome reveals separate human dispersals into Asia

    Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, Moreno Mayar, J. Víctor, Muller, C., Dortch, J., Gilbert, M Thomas P, Lund, O., Wesolowska, A., Karmin, M., Weinert, L. A., Wang, B., Li, J., Tai, S., Xiao, F., Hanihara, T., van Driem, G., Jha, A. R., Ricaut, F., de Knijff, P., Migliano, A. B., Gallego Romero, I., Kristiansen, Karsten, Lambert, D. M., Brunak, Søren, Forster, P., Brinkmann, B., Nehlich, O., Bunce, M., Richards, M., Gupta, R., Bustamante, C. D., Krogh, Anders, Foley, R. A., Lahr, M. M., Balloux, F., Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Wang, J. & Willerslev, Eske, 2011, In: Science. 334, 6052, p. 94-98 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Are East African conservancies too small and isolated to maintain migratory bovid populations?

    Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2011, In: Gnusletter. 29, 2, p. 20-21

    Research output: Contribution to journal › Journal article › Research

  45. Published

    Aspects of RNA Regulation: Non-canonical microRNAs Biogenesis, microRNAs in Pharmacogenomics, and the Evolvability of Alternative Splicing

    Rukov, J. L., 2011, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  46. Published

    Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes

    Valen, E., Preker, P., Andersen, P. R., Zhao, X., Chen, Y., Ender, C., Dueck, A., Meister, G., Sandelin, Albin Gustav & Jensen, T. H., 2011, In: Nature Structural and Molecular Biology. 18, 9, p. 1075–1082 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Bistability in autoimmune diseases

    Rapin, N. P. J., Mosekilde, E. & Lund, O., 2011, In: Autoimmunity. 44, 4, p. 256-260 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    CTLs' repertoire shaping in the thymus: a Monte Carlo simulation

    Castiglione, F., Santoni, D. & Rapin, N. P. J., 2011, In: Autoimmunity. 44, 4, p. 261-270 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

    Enroth, S., Rada-Iglesisas, A., Andersson, Robin, Wallerman, O., Wanders, A., Påhlman, L., Komorowski, J. & Wadelius, C., 2011, In: B M C Cancer. 11, 13 p., 450.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Cross species comparison of C/EBPa and PPAR¿ profiles in mouse and human adipocytes reveals interdependent retention of binding sites

    Schmidt, S. F., Jørgensen, M., Chen, Y., Nielsen, R., Sandelin, Albin Gustav & Mandrup, S., 2011, In: BMC Genomics. 12, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Differential expression of cellular microRNAs in HPV 11, -16, and -45 transfected cells

    Dreher, A., Rossing, M., Kaczkowski, B., Andersen, D. K., Larsen, T. J., Christophersen, M. K., Nielsen, Finn Cilius & Norrild, B., 2011, In: Biochemical and Biophysical Research Communications. 412, 1, p. 20-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Efficient, non-disruptive local moves for Monte Carlo sampling of proteins

    Bottaro, S., Boomsma, Wouter, Johansson, Kristoffer Enøe, Andreetta, C., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2011, Next Generation Statistics in Biosciences: Proceedings of the 30th Leeds Annual Statistical Research (LASR) Workshop. Mardia, K. V., Gusnanto, A., Riley, A. D. & Voss, J. (eds.). University of Leeds, p. 127 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

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