- 2020
- Published
Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
Terkelsen, T., Russo, F., Gromov, P., Haakensen, V. D., Brunak, Søren, Gromova, I., Krogh, Anders & Papaleo, E., 2020, In: Breast Cancer Research. 22, 1, 36 p., 73.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Arabidopsis thaliana Promoter Bidirectionality and Antisense RNAs by Inactivation of Nuclear RNA Decay Pathways
Thieffry, A., Vigh, Maria Louisa, Lange, Jette Bornholdt, Ivanov, M., Brodersen, Peter & Sandelin, Albin Gustav, 2020, In: The Plant Cell. 32, 6, p. 1845-1867 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of transcriptional output and regulation in plants using Cap Analysis of Gene Expression (CAGE)
Thieffry, A., 2020, Department of Biology, Faculty of Science, University of Copenhagen. 128 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Deep Learning for Diagnostic Binary Classification of Multiple-Lesion Skin Diseases
Thomsen, K., Christensen, A. L., Iversen, L., Lomholt, H. B. & Winther, Ole, 2020, In: Frontiers in Medicine. 7, 7 p., 574329.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic review of machine learning for diagnosis and prognosis in dermatology
Thomsen, K., Iversen, L., Titlestad, T. L. & Winther, Ole, 2020, In: Journal of Dermatological Treatment. 31, 5, p. 496-510Research output: Contribution to journal › Review › Research › peer-review
- Published
No Evidence for N7-Methylation of Guanosine (m7G) in Human let-7e
Vinther, Jeppe, 2020, In: Molecular Cell. 79, 2, p. 199-200 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The Draft Genome of Red Lechwe, Kobus leche leche
Wang, B., Wang, Z., Zhou, J., Liu, W., Lin, Z., Zhang, C., Liu, G., Zhou, B., Wan, W., Zhao, R., Wang, W., Heller, Rasmus & Chen, L., 2020, In: Frontiers in Genetics. 11, 7 p., 582638.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena
Westbury, Michael Vincent, Hartmann, S., Barlow, A., Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalen, L., Bibi, F., Werdelin, L., Heller, Rasmus & Hofreiter, M., 2020, In: Science Advances. 6, 11, 11 p., eaay0456.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome
Wu, G., Schmid, M., Rib, Leonor, Polak, P., Meola, N., Sandelin, Albin Gustav & Jensen, T. H., 2020, In: Cell Reports. 30, 7, p. 2387-2401, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The RNA exosome shapes the expression of key protein-coding genes
Wu, M., Karadoulama, Evdoxia, Lloret-llinares, M., Rouviere, J. O., Vaagensø, C. S., Moravec, M., Li, B., Wang, J., Wu, G., Gockert, M. A. M., Pelechano, V., Jensen, T. H. & Sandelin, Albin Gustav, 2020, In: Nucleic Acids Research. 48, 15, p. 8509-8528Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo
Yang, M., Woolfenden, H. C., Zhang, Y., Fang, X., Liu, Q., Vigh, Maria Louisa, Cheema, J., Yang, X., Norris, M., Yu, S., Carbonell, A., Brodersen, Peter, Wang, J. & Ding, Y., 2020, In: Nucleic Acids Research. 48, 15, p. 8767-8781 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival
Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The origin of domestication genes in goats
Zheng, Z., Wang, X., Li, M., Li, Y., Yang, Z., Wang, X., Pan, X., Gong, M., Zhang, Y., Guo, Y., Wang, Y., Liu, J., Cai, Y., Chen, Q., Okpeku, M., Colli, L., Cai, D., Wang, K., Huang, S., Sonstegard, T. S. & 16 others, , 2020, In: Science Advances. 6, 21, eaaz5216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A draft genome sequence of the elusive giant squid, Architeuthis dux
da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, , 2020, In: GigaScience. 9, 1, 12 p., giz152.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
Abildgaard, A. B., Stein, Amelie, Nielsen, S. V., Schultz-Knudsen, Katrine, Papaleo, E., Shrikhande, A., Hoffmann, Eva, Bernstein, I., Gerdes, Anne-Marie Axø, Takahashi, M., Ishioka, C., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: eLife. 8, 28 p., e49138 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Agrawal-Singh, S., Lerdrup, Mads, Gomes, A. R., van de Werken, H. J. G., Johansen, Jens Vilstrup, Andersson, Robin, Sandelin, Albin Gustav, Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms
Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting sequence signals in targeting peptides using deep learning
Almagro Armenteros, J. J., Salvatore, Marco, Emanuelsson, O., Winther, Ole, von Heijne, G., Elofsson, A. & Nielsen, H., 2019, In: Life Science Alliance. 2, 5, 14 p., 201900429.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SignalP 5.0 improves signal peptide predictions using deep neural networks
Armenteros, J. J. A., Tsirigos, Konstantinos, Sønderby, C. K., Petersen, T. N., Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 18 Feb 2019, In: Nature Biotechnology. 37, 4, p. 420-423Research output: Contribution to journal › Journal article › Communication
- Published
Detection of slicer activity by immunopurified plant ARGONAUTE1
Arribas Hernandez, Laura, Vigh, Maria Louisa & Brodersen, Peter, 2019, Plant MicroRNAs: Methods and Protocols. Folter, S. D. (ed.). Humana Press, p. 295-316 22 p. (Methods in Molecular Biology, Vol. 1932).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Multiplex Genome Engineering for Optimizing Bioproduction in Saccharomyces cerevisiae
Auxillos, Jamie Yam, Garcia-Ruiz, E., Jones, S., Li, T., Jiang, S., Dai, J. & Cai, Y., 19 Mar 2019, In: Biochemistry. 58, 11, p. 1492-1500 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A perspective on inverse design of battery interphases using multi-scale modelling, experiments and generative deep learning
Bhowmik, A., Castelli, I. E., Garcia-Lastra, J. M., Bjørn-Jørgensen, P., Winther, Ole & Vegge, T., 2019, In: Energy Storage Materials. 21, p. 446-456Research output: Contribution to journal › Review › Research › peer-review
- Published
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Brown, P., Tan, A-C., El-Esawi, M. A., Liehr, T., Blanck, O., Gladue, D. P., Almeida, G. M. F., Cernava, T., Sorzano, C. O., Yeung, A. W. K., Engel, M. S., Chandrasekaran, A. R., Muth, T., Staege, M. S., Daulatabad, S. V., Widera, D., Zhang, J., Meule, A., Honjo, K., Pourret, O. & 1,560 others, , 2019, In: Database: The Journal of Biological Databases and Curation. 2019, 66 p., baz085.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits
Chen, L., Qin, Q., Jiang, Y., Wang, K., Lin, Z., Li, Z., Bibi, F., Yang, Y., Wang, J., Nie, W., Su, W., Liu, G., Li, Q., Fu, W., Pan, X., Liu, C., Yang, J., Zhang, C., Yin, Y., Wang, Y. & 32 others, , 2019, In: Science. 364, 6446, p. 1152-Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic diversity and novel genome-wide association with fruit morphology in Capsicum, from 746k polymorphic sites
Colonna, V., D’Agostino, N., Garrison, E., Albrechtsen, Anders, Meisner, Jonas, Facchiano, A., Cardi, T. & Tripodi, P., 2019, In: Scientific Reports. 9, 14 p., 10067.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage
Edwards, R. A., Vega, A. A., Norman, H. M., Ohaeri, M., Levi, K., Dinsdale, E. A., Cinek, O., Aziz, R. K., McNair, K., Barr, J. J., Bibby, K., Brouns, S. J. J., Cazares, A., de Jonge, P. A., Desnues, C., Díaz Muñoz, S. L., Fineran, P. C., Kurilshikov, A., Lavigne, R., Mazankova, K. & 97 others, , 2019, In: Nature Microbiology. 4, p. 1727-1736Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing
Enroth, Christel Hougård, Poulsen, L. D., Iversen, S., Kirpekar, F., Albrechtsen, Anders & Vinther, Jeppe, 2019, In: Nucleic Acids Research. 47, 20, 13 p., e126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excess primer degradation by Exo I improves the preparation of 3' cDNA ligation-based sequencing libraries
Enroth, Christel Hougård, Fehler, A. O., Poulsen, L. D. & Vinther, Jeppe, 2019, In: BioTechniques. 67, 3, p. 110-116Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Langevin diffusions on the torus: estimation and applications
García-Portugués, E., Sørensen, Michael, Mardia, K. V. & Hamelryck, Thomas Wim, 2019, In: Statistics and Computing. 29, 1, p. 1-22 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
Garland, W., Comet, I., Wu, M., Radzisheuskaya, A., Rib, Leonor, Vitting-Seerup, K., Lloret-Llinares, M., Sandelin, Albin Gustav, Helin, K. & Jensen, T. H., 2019, In: Cell Reports. 29, 7, p. 1800-1811 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia
Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the possible function of DCL2 as a viral RNA sensor in Arabidopsis
Han, L., 2019, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage
Hanghøj, Kristian Ebbesen, Renaud, Gabriel, Albrechtsen, Anders & Orlando, L., 2019, In: GigaScience. 8, 4, 6 p., giz025.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding
Hanghøj, Kristian Ebbesen, Moltke, Ida, Andersen, P. A., Manica, A. & Korneliussen, Thorfinn Sand, May 2019, In: GigaScience. 8, 5, 9 p., giz034.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Catchment properties and the photosynthetic trait composition of freshwater plant communities
Iversen, L. L., Winkel, A., Baastrup-Spohr, L., Hinke, A. B., Alahuhta, J., Baattrup-Pedersen, A., Birk, S., Brodersen, P., Chambers, P. A., Ecke, F., Feldmann, T., Gebler, D., Heino, J., Jespersen, T. S., Moe, S. J., Riis, T., Sass, L., Vestergaard, O., Maberly, S. C., Sand-jensen, K. & 1 others, , 2019, In: Science. 366, 6467, p. 878-881 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic methods for the analysis of genome-wide data for admixed populations including association studies in Greenlandic Inuit
Jørsboe, E., 2019, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Deconvolution of autoencoders to learn biological regulatory modules from single cell mRNA sequencing data
Kinalis, S., Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2019, In: BMC Bioinformatics. 20, 9 p., 379.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NetSurfP-2.0: improved prediction of protein structural features by integrated deep learning
Klausen, M. S., Jespersen, M. C., Nielsen, H., Jensen, K. K., Jurtz, V. I., Sønderby, C. K., Sommer, M. O. A., Winther, Ole, Nielsen, M., Petersen, Bent & Marcatili, P., 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 6, p. 520-527Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological adaptations in the Arctic cervid, the reindeer (Rangifer tarandus)
Lin, Z., Chen, L., Chen, X., Zhong, Y., Yang, Y., Xia, W., Liu, C., Zhu, W., Wang, H., Yan, B., Yang, Y., Liu, X., Kvie, K. S., Røed, K. H., Wang, K., Xiao, W., Wei, H., Li, G., Heller, R., Gilbert, M. T. P. & 3 others, , 2019, In: Science. 364, 6446, p. 1154-+ 7 p., eaav6312.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete Inactivation of Sebum-Producing Genes Parallels the Loss of Sebaceous Glands in Cetacea
Lopes-Marques, M., Machado, A. M., Alves, L. Q., Fonseca, M. M., Barbosa, S., Sinding, M. S., Rasmussen, M. H., Iversen, M. R., Bertelsen, Mads Frost, Campos, P. F., Rodrigues da Fonseca, Rute Andreia, Ruivo, R. & Castro, L. F. C., 2019, In: MOLECULAR BIOLOGY AND EVOLUTION . 36, 6, p. 1270-1280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicted highly derived class 1 CRISPR-Cas system in Haloarchaea containing diverged Cas5 and Cas7 homologs but no CRISPR array
Makarova, K. S., Karamycheva, S., Shah, S. A., Vestergaard, G. A., Garrett, Roger Antony & Koonin, E. V., 2019, In: FEMS Microbiology Letters. 366, 7, 5 p., fnz079.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, Finn Cilius, 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testing for Hardy-Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data
Meisner, Jonas & Albrechtsen, Anders, 2019, In: Molecular Ecology Resources. 19, 5, p. 1144-1152 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Probabilistic Programming Approach to Protein Structure Superposition
Sanz Moreta, Lys, Al-Sibahi, A. S., Theobald, D., Bullock, W., Rommes, B. N., Manoukian, Andreas & Hamelryck, Thomas Wim, 2019, 2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2019. Baruzzo, G., Daberdaku, S., Di Camillo, B., Furini, S., Giordano, E. D. & Nicosia, G. (eds.). IEEE, 5 p. 8791469Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Fast Translation within the First 45 Codons Decreases mRNA Stability and Increases Premature Transcription Termination in E. coli
Pedersen, Steen, Terkelsen, Thilde Bagger, Eriksen, M., Hauge, M. K., Lund, C. C., Sneppen, Kim & Mitarai, Namiko, 2019, In: Journal of Molecular Biology. 431, 6, p. 1088-1097 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads
Prada Luengo, Inigo, Krogh, Anders, Sørensen, L. M. & Regenberg, Birgitte, 2019, In: BMC Bioinformatics. 20, 9 p., 663.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples
Renaud, Gabriel, Hanghøj, Kristian Ebbesen, Korneliussen, Thorfinn Sand, Willerslev, Eske & Orlando, L., 2019, In: Genetics (Print). 212, 3, p. 587-614 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer
Salgado-Albarrán, M., González-Barrios, R., Guerra-Calderas, L., Alcaraz, N., Sánchez-Correa, T. E., Castro-Hernández, C., Sánchez-Pérez, Y., Aréchaga-Ocampo, E., García-Carrancá, A., de León, D. C., Herrera, L. A., Baumbach, J. & Soto-Reyes, E., 2019, In: Oncogenesis. 8, 12 p., 41.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families
Shah, S. A., Alkhnbashi, O. S., Behler, J., Han, W., She, Q., Hess, W. R., Garrett, Roger Antony & Backofen, R., 2019, In: RNA Biology. 16, 4, p. 530-542 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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