- 2018
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCM2 promotes symmetric inheritance of modified histones during DNA replication
Petryk, N., Dalby, M., Wenger, Alice, Stromme, C. B., Strandsby, A., Andersson, Robin & Groth, Anja, 2018, In: Science. 361, 6409, p. 1389-1392 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MyPMFs: a simple tool for creating statistical potentials to assess protein structural models
Postic, G., Hamelryck, Thomas Wim, Chomilier, J. & Stratmann, D., 2018, In: Biochimie. 151, p. 37-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral health status in historic population: Macroscopic and metagenomic evidence
Willmann, C., Mata, X., Hanghøj, Kristian Ebbesen, Tonasso, L., Tisseyre, L., Jeziorski, C., Cabot, E., Chevet, P., Crubézy, E., Orlando, L., Esclassan, R., Thèves, C. & Caramelli, D., 2018, In: PLOS ONE. 13, 5, 18 p., e0196482.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organism- and disease-specific atlases of transcription start sites using Cap Analysis of Gene Expression (CAGE)
Thodberg, Malte, 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes
Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, Finn Thorup, Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F. J., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, In: PLOS ONE. 13, 8, p. 1-26 e0202530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological and Genetic Adaptations to Diving in Sea Nomads
Ilardo, M. A., Moltke, Ida, Korneliussen, Thorfinn Sand, Cheng, J., Stern, A. J., Racimo, Fernando, Damgaard, P. D. B., Sikora, Martin, Seguin-Orlando, A., Rasmussen, Simon, van den Munckhof, I. C. L., ter Horst, R., Joosten, L. A. B., Netea, M. G., Salingkat, S., Nielsen, Rasmus & Willerslev, Eske, 2018, In: Cell. 173, 3, p. 569-580 12 p., e15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Powerful Inference With the D-Statistic on Low-Coverage Whole-Genome Data
Soraggi, S., Wiuf, Carsten & Albrechtsen, Anders, 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 551-566Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic Programming for Voucher Information Extraction: Preliminary Practical Experiences
Al-Sibahi, A. S., Hamelryck, Thomas Wim & Henglein, Fritz, 2018.Research output: Contribution to conference › Poster › Research
- Published
RNA-Seq for Bacterial Gene Expression
Poulsen, L. D. & Vinther, Jeppe, 2018, In: Current Protocols in Nucleic Acid Chemistry. 73, 1, p. 1-12 e55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation and Maintenance of Transcriptional Specificity
Dalby, M., 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease
Baillie, J. K., Bretherick, A., Haley, C. S., Clohisey, S., Gray, A., Neyton, L. P. A., Barrett, J., Stahl, E. A., Tenesa, A., Andersson, R., Brown, J. B., Faulkner, G. J., Lizio, M., Schaefer, U., Daub, C., Itoh, M., Kondo, N., Lassmann, T., Kawai, J., Mole, D. & 14 others, , 2018, In: PLoS Computational Biology. 14, 3, 24 p., e1005934.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes
Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skind og Ben - Forskning med fokus på dyr fra middelalderens Odense
Brandt, Luise Ørsted, Amsgaard Ebsen, J. & Haase, K., 2018Research output: Non-textual form › Interactive production › Communication
- Published
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno Mayar, J. Víctor, Potter, B. A., Vinner, Lasse, Steinrucken, M., Rasmussen, Simon, Terhorst, J., Kamm, J. A., Albrechtsen, Anders, Malaspinas, A., Sikora, Martin, Reuther, J. D., Irish, J. D., Malhi, R. S., Orlando, L. A. A., Song, Y. S., Nielsen, Rasmus, Meltzer, D. J. & Willerslev, Eske, 2018, In: Nature Genetics. 553, 7687, p. 203-207 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The GBAF chromatin remodeling complex binds H3K27ac and mediates enhancer transcription
Jefimov, K., Alcaraz, N., Kloet, S. L., Värv, S., Sakya, S. A., Vaagenso, C., Vermeulen, M., Aasland, R. & Andersson, Robin, 2018, 31 p.Research output: Working paper › Preprint › Research
- Published
The Muskox Lost a Substantial Part of Its Genetic Diversity on Its Long Road to Greenland
Hansen, C. C. R., Hvilsom, C., Schmidt, N. M., Aastrup, P., de Groot, P. J. V. C., Siegismund, Hans Redlef & Heller, Rasmus, 2018, In: Current Biology. 28, 24, p. 4022-4028, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
Pastuzyn, E. D., Day, C. E., Kearns, R. B., Kyrke-Smith, M., Taibi, A. V., McCormick, J., Yoder, N., Belnap, D. M., qrc243, qrc243, Morado, D. R., Briggs, J. A. G., Feschotte, C. & Shepherd, J. D., 2018, In: Cell. 172, 1-2, p. 275-288, E18 33 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The RNA exosome contributes to gene expression regulation during stem cell differentiation
Llinares, M. L., Karadoulama, Evdoxia, Chen, Y., Wojenski, L. A., Villafano, G. J., Lange, Jette Bornholdt, Andersson, Robin, Core, L., Sandelin, Albin Gustav & Jensen, T. H., 2018, In: Nucleic Acids Research. 46, 21, p. 11502-11513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic history of whaling in the Cantabrian Sea during the 13th-18th centuries: Were North Atlantic right whales (Eubalaena glacialis) the main target species?
Rey-Iglesia, A., Martinez-Cedeira, J., Lopez, A., Fernandez, R. & Campos, P., 2018, In: Journal of Archaeological Science: Reports. 18, p. 393-398 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toroidal Diffusions and Protein Structure Evolution
Garcia Portugues, E., Golden, M., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., 2018, Applied Directional Statistics: Modern Methods and Case Studies. Ley, C. & Verdebout, H. (eds.). CRC Press, 34 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities
Rennie, Sarah, Dalby, M., Lloret-Llinares, M., Bakoulis, Stylianos, Dalager Vaagensø, C., Jensen, T. H. & Andersson, Robin, 2018, In: Nucleic Acids Research. 46, 11, p. 5455-5469 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
Rennie, Sarah, Dalby, M., van Duin, Lucas & Andersson, Robin, 2018, In: Nature Communications. 9, 16 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer RNA instability as a stress response in Escherichia coli: rapid dynamics of the tRNA pool as a function of demand
Sørensen, Michael Askvad, Fehler, A. O. & Svenningsen, Sine Lo, 2018, In: RNA Biology. 15, 4/5, p. 586-593 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vejledning i forskning
Brandt, Luise Ørsted, 2018Research output: Other contribution › Net publication - Internet publication › Education
- 2017
- Published
RNase H sequence preferences influence antisense oligonucleotide efficiency
Kiełpiński, Ł. J., Hagedorn, P. H., Lindow, M. & Vinther, Jeppe, 15 Dec 2017, In: Nucleic Acids Research. 45, 22, p. 12932-12944 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Founder effect of the RETC611Y mutation in multiple endocrine neoplasia 2A in Denmark: a nationwide Study
Sloth Mathiesen, J., Kroustrup, J. P., Vestergaard, P., Krag, K. S., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Gaustadnes, M., Ørntoft, T. F., Rossing, M., Nielsen, Finn Cilius, Albrechtsen, Anders, Brixen, K., Godballe, C. & Frederiksen, A. L., Dec 2017, In: Thyroid. 27, 12, p. 1505-1510 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An introduction to deep learning on biological sequence data: examples and solutions
Jurtz, V. I., Johansen, A. R., Nielsen, M., Almagro Armenteros, J. J., Nielsen, H., Sønderby, C. K., Winther, Ole & Sønderby, S. K., 15 Nov 2017, In: Bioinformatics. 33, 22, p. 3685-3690 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Heat-shock protein 40 is the key farnesylation target in meristem size control, abscisic acid signaling, and drought resistance
Barghetti, A., Sjögren, L. L. E., Floris, M. H. J., Botterweg Paredes, E., Wenkel, Stephan & Brodersen, Peter, 15 Nov 2017, In: Genes & Development. 31, 22, p. 2282-2295 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers
Sikora, M., Seguin-Orlando, A., Sousa, V. C., Albrechtsen, A., Korneliussen, T. S., Ko, A., Rasmussen, S., Dupanloup, I., Nigst, P. R., Bosch, M. D., Renaud, G., Allentoft, M. E., Margaryan, A., Vasilyev, S. V., Veselovskaya, E. V., Borutskaya, S. B., Deviese, T., Comeskey, D., Higham, T., Manica, A. & 7 others, , 3 Nov 2017, In: Science. 358, 6363, p. 659-662 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sugar metabolism of the first thermophilic Planctomycete Thermogutta terrifontis: comparative genomic and transcriptomic approaches
Elcheninov, A. G., Menzel, P., Gudbergsdottir, S. R., Slesarev, A. I., Kadnikov, V. V., Krogh, Anders, Bonch-Osmolovskaya, E. A., Peng, Xu & Kublanov, I. V., 2 Nov 2017, In: Frontiers in Microbiology. 8, 11 p., 2140.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepLoc: prediction of protein subcellular localization using deep learning
Almagro Armenteros, J. J., Sønderby, C. K., Sønderby, S. K., Nielsen, H. & Winther, Ole, 1 Nov 2017, In: Bioinformatics. 33, 21, p. 3387-3395 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample
Jørsboe, E., Hanghøj, Kristian Ebbesen & Albrechtsen, Anders, 1 Oct 2017, In: Bioinformatics. 33, 19, p. 3148-3150 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Climate change and human colonization triggered habitat loss and fragmentation in Madagascar
Salmona, J., Heller, Rasmus, Quéméré, E. & Chikhi, L., Oct 2017, In: Molecular Ecology. 26, 19, p. 5203-5222 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De novo pathway-based biomarker identification
Alcaraz, N., List, M., Batra, R., Vandin, F., Ditzel, H. J. & Baumbach, J., 19 Sep 2017, In: Nucleic Acids Research. 45, 16, 11 p., e151.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assembly and analysis of 100 full MHC haplotypes from the Danish population
Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R. & 39 others, , Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The landscape of isoform switches in human cancers
Vitting-Seerup, K. & Sandelin, Albin Gustav, Sep 2017, In: Molecular Cancer Research. 15, 9, p. 1206-1220 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted next-generation sequencing analysis identifies novel mutations in families with severe familial exudative vitreoretinopathy
Huang, X., Zhuang, H., Wu, J., Li, J., Hu, F., Zheng, Y., Tellier, L. C. A. M., Zhang, S., Gao, F., Zhang, J. & Xu, G., 23 Aug 2017, In: Molecular Vision. 23, p. 605-613 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated expression atlas of miRNAs and their promoters in human and mouse
de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J. & 31 others, , 21 Aug 2017, In: Nature Biotechnology. 35, 9, p. 872-878 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Generative Angular Model of Protein Structure Evolution
Golden, M., Garcia-Portugues, E., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., Aug 2017, In: Molecular Biology and Evolution. 34, 8, p. 2085-2100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Applying targeted next generation sequencing to dried blood spot specimens from suspicious cases identified by tandem mass spectrometry-based newborn screening
Qian, J., Wang, X., Liu, J., Zhong, J., Le, Y., Tellier, L. C. A. M., Liu, C., Jiang, P., Gao, R. & Wang, Y., Aug 2017, In: Journal of Pediatric Endocrinology and Metabolism. 30, 9, p. 979-988 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The whole-genome landscape of medulloblastoma subtypes
Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M. & 67 others, , 19 Jul 2017, In: Nature. 547, 7663, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eight millennia of matrilineal genetic continuity in the South Caucasus
Margaryan, Ashot, Derenko, M., Hovhannisyan, H., Malyarchuk, B., Heller, Rasmus, Khachatryan, Z., Avetisyan, P., Badalyan, R., Bobokhyan, A., Melikyan, V., Sargsyan, G., Piliposyan, A., Simonyan, H., Mkrtchyan, R., Denisova, G., Yepiskoposyan, L., Willerslev, Eske & Allentoft, Morten Erik, 10 Jul 2017, In: Current Biology. 27, 13, p. 2023-2028 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomic changes associated with domestication of the horse
Sanz, P. L., Gamba, C., Gaunitz, C., Der Sarkissian, C., Pruvost, M., Albrechtsen, A., Fages, A. A., Khan, N., Schubert, M., Jagannathan, V., Serres-Armero, A., Kuderna, L. F. K., Povolotskaya, I. S., Seguin-Orlando, A., Lepetz, S., Neuditschko, M., Thèves, C., Alquraishi, S., Alfarhan, A. H., AL-Rasheid, K. & 13 others, , 28 Apr 2017, In: Science. 356, 6336, p. 442-445 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Urup, T., Staunstrup, L. M., Michaelsen, Signe Regner, Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, Shohreh, Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 18 Apr 2017, In: BMC Cancer. 17, 10 p., 278.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chirality in microbial biofilms is mediated by close interactions between the cell surface and the substratum
Jauffred, Liselotte, Vejborg, R. M., Korolev, K. S., Brown, Stanley & Oddershede, L. B., 14 Apr 2017, In: I S M E Journal. 11, 7, p. 1688-1701Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors
Plass, M., Rasmussen, S. H. & Krogh, Anders, 14 Apr 2017, In: PLoS Computational Biology. 13, 4, 26 p., e1005460.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingosine-1-phosphate signaling in inflammatory bowel disease
Nielsen, Ole Haagen, Li, Yuan, Lindbom, B. J. & Coskun, M., Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Molecular clocks indicate turnover and diversification of modern coleoid cephalopods during the Mesozoic Marine Revolution
Tanner, A. R., Fuchs, D., Winkelmann, I. E. H., Gilbert, M Thomas P, Pankey, M. S., Oliveira Ribeiro, Â. M., Kocot, K. M., Halanych, K. M., Oakley, T. H., Rodrigues da Fonseca, Rute Andreia, Pisani, D. & Vinther, J., 15 Mar 2017, In: Proceedings of the Royal Society B: Biological Sciences. 284, 1850, 7 p., 20162818.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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