Sinonasal cancer
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Sinonasal cancer. / Husgafvel-Pursiainen, Kirsti; Carton, Matthieu; Luce, Danièle; Wolff, Henrik; Holmila, Reetta; Schlünssen, Vivi; Bornholdt, Jette; Hansen, Johnni.
Occupational Cancers. ed. / Sisko Anttila; Paolo Boffetta. 2. ed. ed. Springer, 2020. p. 147-178.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - Sinonasal cancer
AU - Husgafvel-Pursiainen, Kirsti
AU - Carton, Matthieu
AU - Luce, Danièle
AU - Wolff, Henrik
AU - Holmila, Reetta
AU - Schlünssen, Vivi
AU - Bornholdt, Jette
AU - Hansen, Johnni
PY - 2020
Y1 - 2020
N2 - Sinonasal cancer, the cancer of the nose and paranasal cavities, is rare with an incidence below 2/100,000 person-year; the incidence is lowest among women and with distinct differences between countries. These variations in incidence are mostly explained by differences in occupational exposure, in particular exposure to wood dust, which is by far the major risk factor. This chapter gives an overview of epidemiological studies on sinonasal cancer dealing with epidemiological evidence for various occupational risk factors, exposure characteristics, tumor pathology, findings from experimental and human studies contributing to understanding of cancer mechanisms, and, finally, with molecular alterations observed in sinonasal cancer tissue available as potential molecular markers. The main studies and their findings as well as the principal pathological features of sinonasal tumors are summarized in tables and exemplified in illustrations.
AB - Sinonasal cancer, the cancer of the nose and paranasal cavities, is rare with an incidence below 2/100,000 person-year; the incidence is lowest among women and with distinct differences between countries. These variations in incidence are mostly explained by differences in occupational exposure, in particular exposure to wood dust, which is by far the major risk factor. This chapter gives an overview of epidemiological studies on sinonasal cancer dealing with epidemiological evidence for various occupational risk factors, exposure characteristics, tumor pathology, findings from experimental and human studies contributing to understanding of cancer mechanisms, and, finally, with molecular alterations observed in sinonasal cancer tissue available as potential molecular markers. The main studies and their findings as well as the principal pathological features of sinonasal tumors are summarized in tables and exemplified in illustrations.
KW - Epidemiology
KW - Genotoxicity
KW - Mechanisms of carcinogenesis
KW - Molecular markers
KW - Occupational factors
KW - Pathology
KW - Sinonasal cancer
KW - Wood dust exposure
U2 - 10.1007/978-3-030-30766-0_7
DO - 10.1007/978-3-030-30766-0_7
M3 - Book chapter
AN - SCOPUS:85088477864
SN - 978-3-030-30765-3
SP - 147
EP - 178
BT - Occupational Cancers
A2 - Anttila, Sisko
A2 - Boffetta, Paolo
PB - Springer
ER -
ID: 247388440