Vinther Lab

The aim of our research is to understand RNA based mechanisms involved in the control of cellular processes, in particular those that are related to disease and affects the efficiency of cell based production systems. Moreover, we want to contribute to the further development of RNA based therapies that utilize our knowledge of RNA based mechanisms.

 

 

 

 

 

I teach a yearly course in Fundamental Bioinformatics (Blok 3). The course is taught in english and is open to students with a background in molecular and cellular biology.

The description of the last version of the course can be found at https://kurser.ku.dk/course/nbib15021u/2021-2022

 

Our group studies RNA based mechanisms involved in the control of cellular processes. Currently, we have a particular interest in answering the following questions:

  • How prevalent are noncanonical 5’ RNA capping in different species?
  • What are the functional consequences of noncanonical RNA capping?
  • How does RNA oxidation influence the regulation of mRNAs in bacterial, yeast and human cells?
  • Can we improve methods for detection of noncanonical RNA capping and RNA oxidation?

We answer these questions using molecular and biochemical methods as well as high throughput methods based on sequencing. We have the computational tools and know-how required to analyse the sequencing data and if the project involves sequencing, the student can choose whether they want to be involved in the computational analysis of the data. Master and bachelor projects are available within the topics listed above. The specific projects depend on the status of the research projects. Thus, if you are interested in doing a project in our group, you should contact Associate Professor Jeppe Vinther to hear more about the current project possibilities. Please attach CV and course/grade transcript with your email.

Working in the Vinther Lab

The reason we work here is to do excellent science and this is our main focus. At the same time the lab should be a good and inspiring place to work.
We will therefore always treat each other with respect and try to help each other whenever possible, both with practical issues and by discussing the science and relevance of our projects.

 

Gabriele Indrisiunaite (Postdoc)
Klara Marie Andersen (MSc)
Sesilie Weiss (MSc)
Line Dahl Poulsen (PhD, Postdoc)
Agnieszka Podolska-Charlery (Postdoc)
Lasse Votborg Novél (MSc)
Lisa Marie Simon (MSc)
Thorsten Brodersen (MSc)
Søren Iversen (MSc)
Lukasz Jan Kielpinski (PhD, Postdoc)
Jakob Lewin Rukov (PhD, Postdoc)
Signe Olivarius (MSc, PhD)
Isabel Bro Høy (MSc)
Mads Marquardt Hedegaard
Ditte Lindschouw (MSc)
Kirsten Reichwald (MSc)
Christian Weile (MSc)

 

 

 

Members

Name Title Phone E-mail
Amal Al-Chaer Laboratory Technician +4535330238 E-mail
Anna Sherwood Postdoc +4535331490 E-mail
Jeppe Vinther Associate Professor +4522840780 E-mail

Contact

Associate Professor Jeppe Vinther
Computational and RNA Biology
Ole Maaløes Vej 5, 3.1.11
2200 Copenhagen N

jvinther@bio.ku.dk
Phone: +45 22 84 07 80

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