Anders Albrechtsen
Professor
- 2012
- Published
SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Nielsen, Rasmus, Korneliussen, Thorfinn Sand, Albrechtsen, Anders, Li, Y. & Wang, J., 2012, In: PLoS ONE. 7, 7, 11 p., e37558.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics
Moltke, Ida, Albrechtsen, Anders, Hansen, Thomas van Overeem, Nielsen, Finn Cilius & Nielsen, Rasmus, 2011, In: Genome Research. 21, 7, p. 1168-80 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, , 2011, In: Science. 334, 6052, p. 94-98 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of allele frequency and association mapping using next-generation sequencing data
Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genotype and SNP calling from next-generation sequencing data
Nielsen, Rasmus, Paul, J. S., Albrechtsen, Anders & Song, Y. S., 2011, In: Nature Reviews. Genetics. 12, 6, p. 443-451 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, Niels, Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Ascertainment biases in SNP chips affect measures of population divergence
Albrechtsen, Anders, Nielsen, Finn Cilius & Nielsen, R., 1 Nov 2010, In: Molecular Biology and Evolution. 27, 11, p. 2534-47 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes
Fosgerau, K., Galle, P., Hansen, T., Albrechtsen, A., Rieper, C. D. L., Pedersen, B. K., Larsen, L. K., Thomsen, A. R., Pedersen, O., Hansen, M. B., Steensberg, A., Fosgerau, K., Galle, P. S., Hansen, T., Albrechtsen, A., Rieper, C. D. L., Pedersen, B. K., Larsen, L. K., Thomsen, A. R., Pedersen, O. & 2 others, , 1 Mar 2010, In: Journal of Endocrinology. 204, 3, p. 265-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, , 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Analyses of 20 Common Obesity Susceptibility Variants
Sandholt, C. H., Sparsø, T., Grarup, Niels, Albrechtsen, Anders, Almind, K., Hansen, L., Toft, U., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2010, In: Diabetes. 59, 7, p. 1667-1673 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, , 2010, In: P L o S One. 5, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer
Hansen, Thomas van Overeem, Jønson, L., Albrechtsen, Anders, Steffensen, A. Y., Bergsten, E. B., Myrhøj, T., Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, 2010, In: Breast Cancer Research and Treatment. 124, 1, p. 259-264 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a novel locus for a USH3 like syndrome combined with congenital cataract
Dad, S., Østergaard, Elsebet, Thykjær, T., Albrechtsen, Anders, Ravn, K. J. T., Rosenberg, T. & Møller, L. B., 2010, In: Clinical Genetics. 78, 4, p. 388-397 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, , 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Segregation distortion in chicken and the evolutionary consequences of female meiotic drive in birds
Axelsson, E. G., Albrechtsen, Anders, Van, A. P., Li, L., Megens, H. J., Vereijken, A. L. J., Crooijmans, R. P. M. A., Groenen, M. A. M., Ellegren, H., Willerslev, Eske & Nielsen, R., 2010, In: Heredity. 105, 3, p. 290-298 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families
Hansen, Thomas van Overeem, Jønson, L., Albrechtsen, Anders, Andersen, M. K., Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, May 2009, In: Breast Cancer Research and Treatment. 115, 2, p. 315-323 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common Greenlandic Inuit BRCA1 RING domain founder mutation
Hansen, T. V. O., Ejlertsen, Bent Laursen, Albrechtsen, Anders, Bergsten, E., Bjerregaard, P., Hansen, T., Myrhoj, T., Nielsen, P. B., Timmermans-Wielenga, V., Andersen, M. K., Jonson, L. & Nielsen, F. C., 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 69-76 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, , 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Darwinian and demographic forces affecting human protein coding genes.
Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Rung, J., Cauchi, S., Albrechtsen, A., Shen, L., Rocheleau, G., Cavalcanti-Proença, C., Bacot, F., Balkau, B., Belisle, A., Borch-Johnsen, K., Charpentier, G., Dina, C., Durand, E., Elliott, P., Hadjadj, S., Järvelin, M-R., Laitinen, J., Lauritzen, T., Marre, M., Mazur, A. & 20 others, , 2009, In: Nature Genetics. 41, 10, p. 1110-1115 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New methods for modeling large scale human genetic variation data
Albrechtsen, Anders, 2009, Museum Tusculanum.Research output: Book/Report › Ph.D. thesis › Research
- Published
Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moltke, Ida, van Overseem Hansen, T., Nielsen, Finn Cilius & Nielsen, Rasmus, 2009, In: Genetic Epidemiology. 33, 3, p. 266-274Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The validation and assessment of machine learning: a game of prediction from high-dimensional data
Pers, Tune H, Albrechtsen, Anders, Holst, C., Sørensen, Thorkild I.A. & Gerds, Thomas Alexander, 2009, In: PLoS ONE. 4, 8, p. e6287Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Grarup, Niels, Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel de novo BRCA2 mutation in a patient with a family history of breast cancer.
Hansen, T. V. O., Bisgaard, M. L., Jønson, L., Albrechtsen, Anders, Filtenborg-Barnkob, B., Eiberg, Hans Rudolf Lytchoff, Ejlertsen, B. & Nielsen, Finn Cilius, 2008, In: BMC Medical Genetics. 9, p. 58Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects
Gjesing, A. P., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2007, In: Diabetic Medicine. 24, 4, p. 392-397 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Bayesian multilocus association method: allowing for higher-order interaction in association studies
Albrechtsen, Anders, Castella, S., Andersen, G., Hansen, T., Pedersen, O. & Nielsen, Rasmus, 2007, In: Genetics. 176, 2, p. 1197-208 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects
Boesgaard, T. W., Castella, S. I., Andersen, G., Albrechtsen, Anders, Sparsø, T. H., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2007, In: Diabetic Medicine. 24, 7, p. 702-706 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes
Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, Niels, Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies
Grarup, Niels, Rose, C. S., Andersson, E. A., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Clausen, J. O., Rasmussen, S. S., Jørgensen, T., Sandbæk, A., Lauritzen, T., Schmitz, O., Hansen, T. & Pedersen, O., 2007, In: Diabetes. 56, 12, p. 3105-3111 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Studies of associations between the Arg389Gly polymorphism of the β1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects
Gjesing, A. P., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2007, In: Diabetic Medicine. 24, 4, p. 392-397 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the peroxisome proliferator-activated receptor δ gene in relation to common metabolic traits in 7,495 middle-aged white people
Grarup, Niels, Albrechtsen, Anders, Ek, J., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, O., 2007, In: Diabetologia. 50, 6, p. 1201-1208 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
A novel -192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-onset Diabetes
Ek, J., Hansen, S. P., Lajer, M., Nicot, C., Boesgaard, T. W., Pruhova, S., Johansen, A., Albrechtsen, Anders, Yderstraede, K., Lauenborg, J., Parrizas, M., Boj, S. F., Jørgensen, T., Borch-Johnsen, K., Damm, Peter, Ferrer, J., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 2006, In: Diabetes. 55, 6, p. 1869-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale study of the -232C> G polymorphism of PCK1 in Type 2 diabetes
Wegner, L., Andersen, G., Albrechtsen, Anders, Sparsø, T., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2006, In: Diabetic Medicine. 23, p. 1140-1144Research output: Contribution to journal › Journal article › Research › peer-review
Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes
Andersen, G., Overgaard, J., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2006, In: Diabetologia. 49, 1, p. 75-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects
Grarup, N., Urhammer, S. A., Ek, J., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, O., 2006, In: Diabetologia. 49, p. 2097-2104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects
Torekov, Signe Sørensen, Larsen, L. H., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2006, In: Diabetologia. 49, 11, p. 2653-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35318880
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published