A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene
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A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene. / Gramlich, Susanne; Liu, Xiaodong; Favre, Adrien; Buerkle, C. Alex; Karrenberg, Sophie.
I: New Phytologist, Bind 235, Nr. 4, 2022, s. 1641-1652.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene
AU - Gramlich, Susanne
AU - Liu, Xiaodong
AU - Favre, Adrien
AU - Buerkle, C. Alex
AU - Karrenberg, Sophie
PY - 2022
Y1 - 2022
N2 - Ecological differentiation can drive speciation but it is unclear how the genetic architecture of habitat-dependent fitness contributes to lineage divergence. We investigated the genetic architecture of cumulative flowering, a fitness component, in second-generation hybrids between Silene dioica and Silene latifolia transplanted into the natural habitat of each species. We used reduced-representation sequencing and Bayesian sparse linear mixed models (BSLMMs) to analyze the genetic control of cumulative flowering in each habitat. Our results point to a polygenic architecture of cumulative flowering. Allelic effects were mostly beneficial or deleterious in one habitat and neutral in the other. Positive-effect alleles often were derived from the native species, whereas negative-effect alleles, at other loci, tended to originate from the non-native species. We conclude that ecological differentiation is governed and maintained by many loci with small, habitat-dependent effects consistent with conditional neutrality. This pattern may result from differences in selection targets in the two habitats and from environmentally dependent deleterious load. Our results further suggest that selection for native alleles and against non-native alleles acts as a barrier to gene flow between species.
AB - Ecological differentiation can drive speciation but it is unclear how the genetic architecture of habitat-dependent fitness contributes to lineage divergence. We investigated the genetic architecture of cumulative flowering, a fitness component, in second-generation hybrids between Silene dioica and Silene latifolia transplanted into the natural habitat of each species. We used reduced-representation sequencing and Bayesian sparse linear mixed models (BSLMMs) to analyze the genetic control of cumulative flowering in each habitat. Our results point to a polygenic architecture of cumulative flowering. Allelic effects were mostly beneficial or deleterious in one habitat and neutral in the other. Positive-effect alleles often were derived from the native species, whereas negative-effect alleles, at other loci, tended to originate from the non-native species. We conclude that ecological differentiation is governed and maintained by many loci with small, habitat-dependent effects consistent with conditional neutrality. This pattern may result from differences in selection targets in the two habitats and from environmentally dependent deleterious load. Our results further suggest that selection for native alleles and against non-native alleles acts as a barrier to gene flow between species.
KW - adaptation
KW - Bayesian sparse linear mixed models (BSLMM)
KW - conditional neutrality
KW - ddRAD-Seq
KW - reproductive isolation
KW - speciation
KW - Silene
KW - LOCAL ADAPTATION
KW - TRADE-OFFS
KW - POPULATION-GENETICS
KW - FLOWERING TIME
KW - TOOL SET
KW - SELECTION
KW - DIVERGENCE
KW - EVOLUTION
KW - DIOICA
KW - RANGE
U2 - 10.1111/nph.18260
DO - 10.1111/nph.18260
M3 - Journal article
C2 - 35586969
VL - 235
SP - 1641
EP - 1652
JO - New Phytologist
JF - New Phytologist
SN - 0028-646X
IS - 4
ER -
ID: 312374867