Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Big Impact of the Tiny : Bacteriophage–Bacteria Interactions in Biofilms. / Hansen, Mads Frederik; Svenningsen, Sine Lo; Røder, Henriette Lyng; Middelboe, Mathias; Burmølle, Mette.

I: Trends in Microbiology, Bind 27, Nr. 9, 2019, s. 739-752.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Hansen, MF, Svenningsen, SL, Røder, HL, Middelboe, M & Burmølle, M 2019, 'Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms', Trends in Microbiology, bind 27, nr. 9, s. 739-752. https://doi.org/10.1016/j.tim.2019.04.006

APA

Hansen, M. F., Svenningsen, S. L., Røder, H. L., Middelboe, M., & Burmølle, M. (2019). Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms. Trends in Microbiology, 27(9), 739-752. https://doi.org/10.1016/j.tim.2019.04.006

Vancouver

Hansen MF, Svenningsen SL, Røder HL, Middelboe M, Burmølle M. Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms. Trends in Microbiology. 2019;27(9):739-752. https://doi.org/10.1016/j.tim.2019.04.006

Author

Hansen, Mads Frederik ; Svenningsen, Sine Lo ; Røder, Henriette Lyng ; Middelboe, Mathias ; Burmølle, Mette. / Big Impact of the Tiny : Bacteriophage–Bacteria Interactions in Biofilms. I: Trends in Microbiology. 2019 ; Bind 27, Nr. 9. s. 739-752.

Bibtex

@article{a088420126b641d08113cd3924238cfb,
title = "Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms",
abstract = "Bacteriophages (phages) have been shaping bacterial ecology and evolution for millions of years, for example, by selecting for defence strategies. Evidence supports that bacterial biofilm formation is one such strategy and that biofilm-mediated protection against phage infection depends on maturation and composition of the extracellular matrix. Interestingly, studies have revealed that phages can induce and strengthen biofilms. Here we review interactions between bacteria and phages in biofilms, discuss the underlying mechanisms, the potential of phage therapy for biofilm control, and emphasize the importance of considering biofilms in future phage research. This is especially relevant as biofilms are associated with increased tolerance towards antibiotics and are implicated in the majority of chronic infections.",
keywords = "bacteriophage–bacteria interactions, biofilms, evolution, extracellular matrix, phage therapy, quorum sensing",
author = "Hansen, {Mads Frederik} and Svenningsen, {Sine Lo} and R{\o}der, {Henriette Lyng} and Mathias Middelboe and Mette Burm{\o}lle",
year = "2019",
doi = "10.1016/j.tim.2019.04.006",
language = "English",
volume = "27",
pages = "739--752",
journal = "Trends in Microbiology",
issn = "0966-842X",
publisher = "Elsevier Ltd. * Trends Journals",
number = "9",

}

RIS

TY - JOUR

T1 - Big Impact of the Tiny

T2 - Bacteriophage–Bacteria Interactions in Biofilms

AU - Hansen, Mads Frederik

AU - Svenningsen, Sine Lo

AU - Røder, Henriette Lyng

AU - Middelboe, Mathias

AU - Burmølle, Mette

PY - 2019

Y1 - 2019

N2 - Bacteriophages (phages) have been shaping bacterial ecology and evolution for millions of years, for example, by selecting for defence strategies. Evidence supports that bacterial biofilm formation is one such strategy and that biofilm-mediated protection against phage infection depends on maturation and composition of the extracellular matrix. Interestingly, studies have revealed that phages can induce and strengthen biofilms. Here we review interactions between bacteria and phages in biofilms, discuss the underlying mechanisms, the potential of phage therapy for biofilm control, and emphasize the importance of considering biofilms in future phage research. This is especially relevant as biofilms are associated with increased tolerance towards antibiotics and are implicated in the majority of chronic infections.

AB - Bacteriophages (phages) have been shaping bacterial ecology and evolution for millions of years, for example, by selecting for defence strategies. Evidence supports that bacterial biofilm formation is one such strategy and that biofilm-mediated protection against phage infection depends on maturation and composition of the extracellular matrix. Interestingly, studies have revealed that phages can induce and strengthen biofilms. Here we review interactions between bacteria and phages in biofilms, discuss the underlying mechanisms, the potential of phage therapy for biofilm control, and emphasize the importance of considering biofilms in future phage research. This is especially relevant as biofilms are associated with increased tolerance towards antibiotics and are implicated in the majority of chronic infections.

KW - bacteriophage–bacteria interactions

KW - biofilms

KW - evolution

KW - extracellular matrix

KW - phage therapy

KW - quorum sensing

U2 - 10.1016/j.tim.2019.04.006

DO - 10.1016/j.tim.2019.04.006

M3 - Review

C2 - 31128928

AN - SCOPUS:85065885980

VL - 27

SP - 739

EP - 752

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

IS - 9

ER -

ID: 224024255