Chromosome-scale haplotype-resolved pangenomics
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Complete pangenomics is crucial for understanding genetic diversity and evolution across the tree of life. Chromosome-scale, haplotype-resolved pangenomics allows complex structural variations, long-range interactions, and associated functions to be discerned in species populations. We explore the need for high-resolution pangenomes, discuss computational strategies for their development, and describe applications in biodiversity and human health.
Originalsprog | Engelsk |
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Tidsskrift | Trends in Genetics |
Vol/bind | 38 |
Udgave nummer | 11 |
Sider (fra-til) | 1103-1107 |
Antal sider | 5 |
ISSN | 0168-9525 |
DOI | |
Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:
S.G. acknowledges the support from the Novo Nordisk Foundation ( NNF21OC0069089 ). The authors acknowledge the valuable comments of anonymous reviewers.
Publisher Copyright:
© 2022 Elsevier Ltd
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