DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2
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Originalsprog | Engelsk |
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Artikelnummer | 1445 |
Tidsskrift | Nature Communications |
Vol/bind | 15 |
Udgave nummer | 1 |
Antal sider | 16 |
ISSN | 2041-1723 |
DOI | |
Status | Udgivet - 2024 |
Bibliografisk note
Funding Information:
We thank Benjamin Schuler and Daniel Nettels for support using the data analysis toolbox Fretica. We thank Beat Fierz for technical assistance with nucleosome preparation. We thank Magnús Kristjánsson, Erna Magnúsdóttir, and Erik Holmstrom for stimulating discussions, and Matthías Valdimarsson, Sarah Ruidiaz, and Mahtab Hafizi for technical assistance. This work was supported by funding from the European Research Council (ERC StG, 101040601-PIONEER, to P.O.H.), the Icelandic Research Fund (grant nr. 2659105, to P.O.H.), the University of Iceland Doctoral Fund (to S.B.), the Max Planck Society (to J.T.B.), the University of Auckland (to J.A.P.M.), the Novo Nordisk Foundation to the Challenge centre REPIN (#NNF18OC0033926 to B.B.K.), and by cOpenNMR, an infrastructure granted from the Novo Nordisk Foundation (#NNF18OC0032996).
Publisher Copyright:
© The Author(s) 2024.
ID: 384025450