Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.
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Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells. / Ballard, S A; Williamson, M; Adler, B; Vinh, T; Faine, S.
I: Journal of Medical Microbiology, Bind 21, Nr. 1, 1986, s. 59-67.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.
AU - Ballard, S A
AU - Williamson, M
AU - Adler, B
AU - Vinh, T
AU - Faine, S
N1 - Keywords: Adhesiveness; Animals; Antibodies, Bacterial; Antigen-Antibody Reactions; Cells, Cultured; Epithelium; Fluorescent Antibody Technique; Kidney Tubules; Leptospira; Mice; Microscopy, Electron, Scanning
PY - 1986
Y1 - 1986
N2 - A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. Udgivelsesdato: 1986-Feb
AB - A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. Udgivelsesdato: 1986-Feb
M3 - Journal article
C2 - 3512834
VL - 21
SP - 59
EP - 67
JO - Journal of Medical Microbiology
JF - Journal of Medical Microbiology
SN - 0022-2615
IS - 1
ER -
ID: 3046356