IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

IsoformSwitchAnalyzeR : analysis of changes in genome-wide patterns of alternative splicing and its functional consequences. / Vitting-Seerup, Kristoffer; Sandelin, Albin.

I: Bioinformatics, Bind 35, Nr. 21, 2019, s. 4469-4471.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Vitting-Seerup, K & Sandelin, A 2019, 'IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences', Bioinformatics, bind 35, nr. 21, s. 4469-4471. https://doi.org/10.1093/bioinformatics/btz247

APA

Vitting-Seerup, K., & Sandelin, A. (2019). IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences. Bioinformatics, 35(21), 4469-4471. https://doi.org/10.1093/bioinformatics/btz247

Vancouver

Vitting-Seerup K, Sandelin A. IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences. Bioinformatics. 2019;35(21):4469-4471. https://doi.org/10.1093/bioinformatics/btz247

Author

Vitting-Seerup, Kristoffer ; Sandelin, Albin. / IsoformSwitchAnalyzeR : analysis of changes in genome-wide patterns of alternative splicing and its functional consequences. I: Bioinformatics. 2019 ; Bind 35, Nr. 21. s. 4469-4471.

Bibtex

@article{252d1c66a38b4057ba5c410d4e2a4183,
title = "IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences",
abstract = "SUMMARY: Alternative splicing is an important mechanism involved in both health and disease. Recent work highlights the importance of investigating genome-wide changes in patters of splicing and the subsequent functional consequences. Current computational methods only support such analysis on a gene-by-gene basis. Therefore, we extended IsoformSwitchAnalyzeR R library to enable analysis of genome-wide changes in specific types of alternative splicing and predicted functional consequences of the resulting isoform switches. As a case study, we analyzed RNA-seq data from The Cancer Genome Atlas and found systematic changes in alternative splicing and the consequences of the associated isoform switches.AVAILABILITY: Windows, Linux and Mac OS: http://bioconductor.org/packages/IsoformSwitchAnalyzeR.SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.",
author = "Kristoffer Vitting-Seerup and Albin Sandelin",
note = "{\textcopyright} The Author(s) (2019). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.",
year = "2019",
doi = "10.1093/bioinformatics/btz247",
language = "English",
volume = "35",
pages = "4469--4471",
journal = "Computer Applications in the Biosciences",
issn = "1471-2105",
publisher = "Oxford University Press",
number = "21",

}

RIS

TY - JOUR

T1 - IsoformSwitchAnalyzeR

T2 - analysis of changes in genome-wide patterns of alternative splicing and its functional consequences

AU - Vitting-Seerup, Kristoffer

AU - Sandelin, Albin

N1 - © The Author(s) (2019). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

PY - 2019

Y1 - 2019

N2 - SUMMARY: Alternative splicing is an important mechanism involved in both health and disease. Recent work highlights the importance of investigating genome-wide changes in patters of splicing and the subsequent functional consequences. Current computational methods only support such analysis on a gene-by-gene basis. Therefore, we extended IsoformSwitchAnalyzeR R library to enable analysis of genome-wide changes in specific types of alternative splicing and predicted functional consequences of the resulting isoform switches. As a case study, we analyzed RNA-seq data from The Cancer Genome Atlas and found systematic changes in alternative splicing and the consequences of the associated isoform switches.AVAILABILITY: Windows, Linux and Mac OS: http://bioconductor.org/packages/IsoformSwitchAnalyzeR.SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

AB - SUMMARY: Alternative splicing is an important mechanism involved in both health and disease. Recent work highlights the importance of investigating genome-wide changes in patters of splicing and the subsequent functional consequences. Current computational methods only support such analysis on a gene-by-gene basis. Therefore, we extended IsoformSwitchAnalyzeR R library to enable analysis of genome-wide changes in specific types of alternative splicing and predicted functional consequences of the resulting isoform switches. As a case study, we analyzed RNA-seq data from The Cancer Genome Atlas and found systematic changes in alternative splicing and the consequences of the associated isoform switches.AVAILABILITY: Windows, Linux and Mac OS: http://bioconductor.org/packages/IsoformSwitchAnalyzeR.SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

U2 - 10.1093/bioinformatics/btz247

DO - 10.1093/bioinformatics/btz247

M3 - Journal article

C2 - 30989184

VL - 35

SP - 4469

EP - 4471

JO - Computer Applications in the Biosciences

JF - Computer Applications in the Biosciences

SN - 1471-2105

IS - 21

ER -

ID: 223452659