Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development
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Leng et al. performed a comprehensive survey of transcriptional activities between biparental and uniparental embryos by single-cell RNA sequencing. They provide insights into the critical features of parental genome activation before implantation and help elucidate parent-of-origin effects in early human development.
Originalsprog | Engelsk |
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Tidsskrift | Cell Stem Cell |
Vol/bind | 25 |
Udgave nummer | 5 |
Sider (fra-til) | 697-712, e1-e6 |
ISSN | 1934-5909 |
DOI | |
Status | Udgivet - 2019 |
ID: 230095323