The cell biology of mitotic recombination in saccharomyces cerevisiae
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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The cell biology of mitotic recombination in saccharomyces cerevisiae. / Lisby, Michael; Rothstein, Rodney.
Molecular Genetics of Recombination. red. / Andres Aquilera; Rodney Rothstein. 2007. s. 335-362 (Topics in Current Genetics, Bind 17).Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - The cell biology of mitotic recombination in saccharomyces cerevisiae
AU - Lisby, Michael
AU - Rothstein, Rodney
PY - 2007/5/2
Y1 - 2007/5/2
N2 - Genetic recombination relies on a number of biochemical activities that must be present at the right time and place in order for two DNA molecules to be recombined properly. Recent advances in real-time fluorescence microscopy provide us with a glimpse of homologous recombination taking place in living cells. These approaches reveal that homologous recombination is highly choreographed in vivo with its spatio-temporal organization being dependent on both cell cycle phase and the nature of the initiating DNA lesion. In this chapter, we review the cell biology of homologous recombination in mitotic cells with the main focus on the yeast Saccharomyces cerevisiae but also drawing parallels to other eukaryotic organisms.
AB - Genetic recombination relies on a number of biochemical activities that must be present at the right time and place in order for two DNA molecules to be recombined properly. Recent advances in real-time fluorescence microscopy provide us with a glimpse of homologous recombination taking place in living cells. These approaches reveal that homologous recombination is highly choreographed in vivo with its spatio-temporal organization being dependent on both cell cycle phase and the nature of the initiating DNA lesion. In this chapter, we review the cell biology of homologous recombination in mitotic cells with the main focus on the yeast Saccharomyces cerevisiae but also drawing parallels to other eukaryotic organisms.
UR - http://www.scopus.com/inward/record.url?scp=34247501228&partnerID=8YFLogxK
U2 - 10.1007/4735_2006_0212
DO - 10.1007/4735_2006_0212
M3 - Book chapter
AN - SCOPUS:34247501228
SN - 3540710205
SN - 9783540710202
T3 - Topics in Current Genetics
SP - 335
EP - 362
BT - Molecular Genetics of Recombination
A2 - Aquilera, Andres
A2 - Rothstein, Rodney
ER -
ID: 241305824