Vertical and horizontal gene transfer shaped plant colonization and biomass degradation in the fungal genus Armillaria

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

  • Neha Sahu
  • Boris Indic
  • Johanna Wong-Bajracharya
  • Zsolt Merényi
  • Huei Mien Ke
  • Steven Ahrendt
  • Tori Lee Monk
  • Sándor Kocsubé
  • Elodie Drula
  • Anna Lipzen
  • Balázs Bálint
  • Bernard Henrissat
  • Bill Andreopoulos
  • Francis M. Martin
  • Daniel Rigling
  • Kathryn L. Ford
  • Gary D. Foster
  • Jasmyn Pangilinan
  • Alexie Papanicolaou
  • Kerrie Barry
  • Kurt LaButti
  • Máté Virágh
  • Maxim Koriabine
  • Mi Yan
  • Robert Riley
  • Simang Champramary
  • Krista L. Plett
  • Igor V. Grigoriev
  • Isheng Jason Tsai
  • Jason Slot
  • György Sipos
  • Jonathan Plett
  • László G. Nagy
The fungal genus Armillaria contains necrotrophic pathogens and some of the largest terrestrial organisms that cause tremendous losses in diverse ecosystems, yet how they evolved pathogenicity in a clade of dominantly non-pathogenic wood degraders remains elusive. Here we show that Armillaria species, in addition to gene duplications and de novo gene origins, acquired at least 1,025 genes via 124 horizontal gene transfer events, primarily from Ascomycota. Horizontal gene transfer might have affected plant biomass degrading and virulence abilities of Armillaria, and provides an explanation for their unusual, soft rot-like wood decay strategy. Combined multi-species expression data revealed extensive regulation of horizontally acquired and wood-decay related genes, putative virulence factors and two novel conserved pathogenicity-induced small secreted proteins, which induced necrosis in planta. Overall, this study details how evolution knitted together horizontally and vertically inherited genes in complex adaptive traits of plant biomass degradation and pathogenicity in important fungal pathogens.
OriginalsprogEngelsk
TidsskriftNature Microbiology
Vol/bind8
Antal sider27
ISSN2058-5276
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
We acknowledge support by the ‘Momentum’ programme of the Hungarian Academy of Sciences (contract no. LP2019-13/2019 to L.G.N.) the European Research Council (grant no. 758161 to L.G.N.) as well as the Eotvos Lorand Research Network (SA-109/2021). G.S. acknowledges support by the Hungarian National Research, Development, and Innovation Office (GINOP-2.3.2-15-2016-00052). The work (proposals: https://doi.org/10.46936/10.25585/60001060 and https://doi.org/10.46936/10.25585/60001019 ) conducted by the US Department of Energy (DOE) Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE Office of Science User Facility, is supported by the Office of Science of the US DOE operated under contract no. DE-AC02-05CH11231. The research was performed in collaboration with the Genomics and Bioinformatics Core Facility at the Szentágothai Research Centre of the University of Pécs. Ian Hood and Pam Taylor (Scion Research, New Zealand Forest Research Institute Ltd.) kindly provided the A. nova-zealandiae 2840 strain. D. Lindner (Forest Products Laboratory, USA) kindly shared strains of A. borealis and A. ectypa for sequencing. We appreciate the permission of G. Bonito for using the genome of Flagelloscypha sp.

Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Nature Limited.

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