Lake morphometric features like surface area, volume, mean, and maximum depth are important predictors of many physical, biological, and ecological processes. Lake bathymetric maps that present the lake basin contours are thus an integral part of limnological investigations. Accurate but cumbersome traditional bathymetric surveys measure the depth using a lead line or echosounder. Recently, airborne bathymetric mapping using imagery or laser scanning has been attempted in shallow freshwater and coastal habitats. However, these methods depend on the ability of light to penetrate the water column, which can be problematic in eutrophic lakes and shallow lakes. To alleviate these issues, we developed and tested a deep learning model (based on the U-net) using data from 153 lakes in Denmark to predict bathymetry using the topography of the surrounding terrain. The deep learning model performed much better (pixel-wise mean absolute error: validation set = 1.75 and test set = 2.15 m) than baseline interpolation approaches (validation set = 3.12 m). In addition, the deep learning model generated more realistic bathymetry maps that did not suffer from interpolation artifacts. We find that the model performance improves slightly with increasing model size (number of trainable parameters) and the extent of the surrounding terrain. In addition, our pretraining procedure improved performance and reduced the time for model convergence. Because the model only relies on digital elevation data which are widely available, it can be fine-tuned and used to predict lake bathymetry in other geographical regions.