Microbiomics

Welcome to the Microbiomics Lab at the Section of Microbiology

Søren Sørensen’s research group – the Microbiomics Lab – is dedicated to exploring the fascinating and complex world of microbial interactions. We aim at unraveling the mechanisms driving microbial community dynamics and their implications for health, agriculture, and biotechnology.

Social Evolution and Microbial Ecology

In the Microbiomics Lab, we investigate the fundamental principles governing microbial evolution and ecology. A particular focus is on horizontal gene transfer (HGT) and the production of “common goods,” such as signaling molecules and enzymes, which are essential for microbial interactions. These processes are critical for understanding microbial behavior and have transformative potential for applications like antibiotic development and sustainable agriculture.

Microbiome Assembly and Function

The team uses advanced molecular techniques to study microbiome assembly and functionality across diverse ecosystems. From longitudinal studies on human gut microbiomes and their links to health outcomes like asthma to investigating root-associated microbial communities in plants, we strive to understand the interplay between microorganisms and their environments. We are also pioneering efforts to design “collaboromes”, synthetic microbial consortia tailored for specific functions.

Antibiotic Resistance and Genetic Adaptation

A cornerstone of our research explores the role of mobile genetic elements, such as plasmids, in facilitating HGT and antibiotic resistance. By decoding genetic exchange networks within microbial communities, we aim to uncover how these mechanisms sustain cooperation and drive bacterial adaptability. This work is crucial for tackling antibiotic resistance and understanding the stability of beneficial microbiomes.

At the Microbiomics Lab, our interdisciplinary and innovative approach pushes the boundaries of microbiological research, offering insights that pave the way for scientific breakthroughs and practical solutions to global challenges. Join us in exploring the hidden world of microbes and their extraordinary potential.