A Critical Review of Concepts and Methods Used in Classical Genome Analysis

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A Critical Review of Concepts and Methods Used in Classical Genome Analysis. / Seberg, Ole; Petersen, Gitte.

In: Botanical Review, Vol. 64, No. 4, 1998, p. 372-417.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Seberg, O & Petersen, G 1998, 'A Critical Review of Concepts and Methods Used in Classical Genome Analysis', Botanical Review, vol. 64, no. 4, pp. 372-417. https://doi.org/10.1007/BF02857624

APA

Seberg, O., & Petersen, G. (1998). A Critical Review of Concepts and Methods Used in Classical Genome Analysis. Botanical Review, 64(4), 372-417. https://doi.org/10.1007/BF02857624

Vancouver

Seberg O, Petersen G. A Critical Review of Concepts and Methods Used in Classical Genome Analysis. Botanical Review. 1998;64(4):372-417. https://doi.org/10.1007/BF02857624

Author

Seberg, Ole ; Petersen, Gitte. / A Critical Review of Concepts and Methods Used in Classical Genome Analysis. In: Botanical Review. 1998 ; Vol. 64, No. 4. pp. 372-417.

Bibtex

@article{e4d1e11074c911dbbee902004c4f4f50,
title = "A Critical Review of Concepts and Methods Used in Classical Genome Analysis",
abstract = "A short account of the development of classical genome analysis, the analysis of chromosome behaviour in metaphase I of meiosis, primarily in interspecific hybrids, is given. The application of the concept of homology to describe chromosome pairing between the respective chromosomes of a pair during meiosis is traced, and the relationship between this use of homology and the concept of homology as common ancestry is discussed at length. To equate the two concepts has led to the erroneous assumption that levels of chromosome pairing is an indication of phylogenetic relationship. Even accepting the fundamental premises, genome analysis is burdened by observational difficulties. Hence, chromosome pairing has been shown to be under genetic control and is also influenced by environmental conditions. Additionally, basic biological observations such as the distribution of meiotic configurations or the identity of the individual chromosomes are frequently neglected. Data from chromosome pairing are captured as pair-wise comparisons and are amenable only to phenetic analysis, and hence are not suited for phylogenetic inferences. As currently perceived, genome analysis may have a role to play in plant breeding but it has no place in systematics. With an increased knowledge and understanding of the mechanism behind meiosis, data useful in a systematic context may eventually be produced.",
author = "Ole Seberg and Gitte Petersen",
year = "1998",
doi = "10.1007/BF02857624",
language = "English",
volume = "64",
pages = "372--417",
journal = "The Botanical Review",
issn = "0006-8101",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - A Critical Review of Concepts and Methods Used in Classical Genome Analysis

AU - Seberg, Ole

AU - Petersen, Gitte

PY - 1998

Y1 - 1998

N2 - A short account of the development of classical genome analysis, the analysis of chromosome behaviour in metaphase I of meiosis, primarily in interspecific hybrids, is given. The application of the concept of homology to describe chromosome pairing between the respective chromosomes of a pair during meiosis is traced, and the relationship between this use of homology and the concept of homology as common ancestry is discussed at length. To equate the two concepts has led to the erroneous assumption that levels of chromosome pairing is an indication of phylogenetic relationship. Even accepting the fundamental premises, genome analysis is burdened by observational difficulties. Hence, chromosome pairing has been shown to be under genetic control and is also influenced by environmental conditions. Additionally, basic biological observations such as the distribution of meiotic configurations or the identity of the individual chromosomes are frequently neglected. Data from chromosome pairing are captured as pair-wise comparisons and are amenable only to phenetic analysis, and hence are not suited for phylogenetic inferences. As currently perceived, genome analysis may have a role to play in plant breeding but it has no place in systematics. With an increased knowledge and understanding of the mechanism behind meiosis, data useful in a systematic context may eventually be produced.

AB - A short account of the development of classical genome analysis, the analysis of chromosome behaviour in metaphase I of meiosis, primarily in interspecific hybrids, is given. The application of the concept of homology to describe chromosome pairing between the respective chromosomes of a pair during meiosis is traced, and the relationship between this use of homology and the concept of homology as common ancestry is discussed at length. To equate the two concepts has led to the erroneous assumption that levels of chromosome pairing is an indication of phylogenetic relationship. Even accepting the fundamental premises, genome analysis is burdened by observational difficulties. Hence, chromosome pairing has been shown to be under genetic control and is also influenced by environmental conditions. Additionally, basic biological observations such as the distribution of meiotic configurations or the identity of the individual chromosomes are frequently neglected. Data from chromosome pairing are captured as pair-wise comparisons and are amenable only to phenetic analysis, and hence are not suited for phylogenetic inferences. As currently perceived, genome analysis may have a role to play in plant breeding but it has no place in systematics. With an increased knowledge and understanding of the mechanism behind meiosis, data useful in a systematic context may eventually be produced.

U2 - 10.1007/BF02857624

DO - 10.1007/BF02857624

M3 - Journal article

VL - 64

SP - 372

EP - 417

JO - The Botanical Review

JF - The Botanical Review

SN - 0006-8101

IS - 4

ER -

ID: 207432