Analysis of morphogenetic mutants of hydra - I. The Aberrant

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Analysis of morphogenetic mutants of hydra - I. The Aberrant. / Schaller, H. C.; Schmidt, T.; Flick, K.; Grimmelikhuijzen, C. J.P.

In: Wilhelm Roux's Archives of Developmental Biology, Vol. 183, No. 3, 09.1977, p. 193-206.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Schaller, HC, Schmidt, T, Flick, K & Grimmelikhuijzen, CJP 1977, 'Analysis of morphogenetic mutants of hydra - I. The Aberrant', Wilhelm Roux's Archives of Developmental Biology, vol. 183, no. 3, pp. 193-206. https://doi.org/10.1007/BF00867320

APA

Schaller, H. C., Schmidt, T., Flick, K., & Grimmelikhuijzen, C. J. P. (1977). Analysis of morphogenetic mutants of hydra - I. The Aberrant. Wilhelm Roux's Archives of Developmental Biology, 183(3), 193-206. https://doi.org/10.1007/BF00867320

Vancouver

Schaller HC, Schmidt T, Flick K, Grimmelikhuijzen CJP. Analysis of morphogenetic mutants of hydra - I. The Aberrant. Wilhelm Roux's Archives of Developmental Biology. 1977 Sep;183(3):193-206. https://doi.org/10.1007/BF00867320

Author

Schaller, H. C. ; Schmidt, T. ; Flick, K. ; Grimmelikhuijzen, C. J.P. / Analysis of morphogenetic mutants of hydra - I. The Aberrant. In: Wilhelm Roux's Archives of Developmental Biology. 1977 ; Vol. 183, No. 3. pp. 193-206.

Bibtex

@article{0c7af07995064b7792f6415943abcdae,
title = "Analysis of morphogenetic mutants of hydra - I. The Aberrant",
abstract = "A mutant of Hydra attenuata is analysed, the aberrant, which is distinct from the wild type in having a smaller head with fewer tentacles and only half the number of head-specific cells. The rate of head and foot regeneration and the doubling time are slower in aberrants than in normal hydra. The lower head-forming potential is paralleled by a reduced concentration of head-specific morphogens: compared to the wild type, in the aberrant the concentration of head activator is reduced to 70% in the head and to 50% in the body, the concentration of head inhibitor is reduced to 50% in the head and to 80% in the body. The aberrant is more sensitive (3 times) to added head activator and less sensitive (>5 times) to added head inhibitor than the wild type. The slower rate of foot regeneration is paralleled by a lower content of foot-specific morphogens: compared to the wild type, in the aberrant the foot activator is reduced to 40% and the foot inhibitor to 70%.",
keywords = "Head formation, Hydra mutant, Morphogenetic substances",
author = "Schaller, {H. C.} and T. Schmidt and K. Flick and Grimmelikhuijzen, {C. J.P.}",
year = "1977",
month = sep,
doi = "10.1007/BF00867320",
language = "English",
volume = "183",
pages = "193--206",
journal = "Development Genes and Evolution",
issn = "0949-944X",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Analysis of morphogenetic mutants of hydra - I. The Aberrant

AU - Schaller, H. C.

AU - Schmidt, T.

AU - Flick, K.

AU - Grimmelikhuijzen, C. J.P.

PY - 1977/9

Y1 - 1977/9

N2 - A mutant of Hydra attenuata is analysed, the aberrant, which is distinct from the wild type in having a smaller head with fewer tentacles and only half the number of head-specific cells. The rate of head and foot regeneration and the doubling time are slower in aberrants than in normal hydra. The lower head-forming potential is paralleled by a reduced concentration of head-specific morphogens: compared to the wild type, in the aberrant the concentration of head activator is reduced to 70% in the head and to 50% in the body, the concentration of head inhibitor is reduced to 50% in the head and to 80% in the body. The aberrant is more sensitive (3 times) to added head activator and less sensitive (>5 times) to added head inhibitor than the wild type. The slower rate of foot regeneration is paralleled by a lower content of foot-specific morphogens: compared to the wild type, in the aberrant the foot activator is reduced to 40% and the foot inhibitor to 70%.

AB - A mutant of Hydra attenuata is analysed, the aberrant, which is distinct from the wild type in having a smaller head with fewer tentacles and only half the number of head-specific cells. The rate of head and foot regeneration and the doubling time are slower in aberrants than in normal hydra. The lower head-forming potential is paralleled by a reduced concentration of head-specific morphogens: compared to the wild type, in the aberrant the concentration of head activator is reduced to 70% in the head and to 50% in the body, the concentration of head inhibitor is reduced to 50% in the head and to 80% in the body. The aberrant is more sensitive (3 times) to added head activator and less sensitive (>5 times) to added head inhibitor than the wild type. The slower rate of foot regeneration is paralleled by a lower content of foot-specific morphogens: compared to the wild type, in the aberrant the foot activator is reduced to 40% and the foot inhibitor to 70%.

KW - Head formation

KW - Hydra mutant

KW - Morphogenetic substances

UR - http://www.scopus.com/inward/record.url?scp=0017643326&partnerID=8YFLogxK

U2 - 10.1007/BF00867320

DO - 10.1007/BF00867320

M3 - Journal article

AN - SCOPUS:0017643326

VL - 183

SP - 193

EP - 206

JO - Development Genes and Evolution

JF - Development Genes and Evolution

SN - 0949-944X

IS - 3

ER -

ID: 370741976