Bacterial chromosomes and their replication
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Bacterial chromosomes and their replication. / Frimodt-Møller, Jakob; Boesen, Thias Oberg; Charbon, Godefroid; Løbner-Olesen, Anders.
Molecular Medical Microbiology. ed. / Yi-Wei Tang; Musa Y. Hindiyeh; Dongyou Liu; Andrew Sails; Paul Spearman; Jing-Ren Zhang. Vol. 1 3. ed. Academic Press, 2024. p. 279-307.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - Bacterial chromosomes and their replication
AU - Frimodt-Møller, Jakob
AU - Boesen, Thias Oberg
AU - Charbon, Godefroid
AU - Løbner-Olesen, Anders
PY - 2024
Y1 - 2024
N2 - This chapter reviews the current knowledge on the organization and replication of bacterial genomes with a special emphasis on the initiation of DNA replication. Most bacteria contain one chromosome, however a few species, like the human pathogen Vibrio cholerae, carry a secondary chromosome. We discuss structures of origins of replication, the function of initiator proteins, the cell cycle regulation of initiation of replication, and the loading and assembly of replisomes. This is predominantly described for Escherichia coli, but parallels are drawn to Bacillus subtilis along with important pathogenic bacteria when relevant.
AB - This chapter reviews the current knowledge on the organization and replication of bacterial genomes with a special emphasis on the initiation of DNA replication. Most bacteria contain one chromosome, however a few species, like the human pathogen Vibrio cholerae, carry a secondary chromosome. We discuss structures of origins of replication, the function of initiator proteins, the cell cycle regulation of initiation of replication, and the loading and assembly of replisomes. This is predominantly described for Escherichia coli, but parallels are drawn to Bacillus subtilis along with important pathogenic bacteria when relevant.
KW - chromosome replication during infection
KW - Chromosome structure
KW - global chromosome organization
KW - origin structure
KW - regulation of replication initiation
KW - replication of chromids
KW - replisome structure and dynamics
KW - the bacterial cell cycle
U2 - 10.1016/B978-0-12-818619-0.00007-1
DO - 10.1016/B978-0-12-818619-0.00007-1
M3 - Book chapter
AN - SCOPUS:85184317785
SN - 978-0-12-818610-0
VL - 1
SP - 279
EP - 307
BT - Molecular Medical Microbiology
A2 - Tang, Yi-Wei
A2 - Hindiyeh, Musa Y.
A2 - Liu, Dongyou
A2 - Sails, Andrew
A2 - Spearman, Paul
A2 - Zhang, Jing-Ren
PB - Academic Press
ER -
ID: 374456454