BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis
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BloodSpot 3.0 : a database of gene and protein expression data in normal and malignant haematopoiesis. / Gíslason, Magnús H; Demircan, Gül Sude; Prachar, Marek; Furtwängler, Benjamin; Schwaller, Juerg; Schoof, Erwin m; Porse, Bo torben; Rapin, Nicolas; Bagger, Frederik otzen.
In: Nucleic acids symposium series, Vol. 52, No. D1, 2024, p. D1138–D1142.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - BloodSpot 3.0
T2 - a database of gene and protein expression data in normal and malignant haematopoiesis
AU - Gíslason, Magnús H
AU - Demircan, Gül Sude
AU - Prachar, Marek
AU - Furtwängler, Benjamin
AU - Schwaller, Juerg
AU - Schoof, Erwin m
AU - Porse, Bo torben
AU - Rapin, Nicolas
AU - Bagger, Frederik otzen
PY - 2024
Y1 - 2024
N2 - BloodSpot is a specialised database integrating gene expression data from acute myeloid leukaemia (AML) patients related to blood cell development and maturation. The database and interface has helped numerous researchers and clinicians to quickly get an overview of gene expression patterns in healthy and malignant haematopoiesis. Here, we present an update to our framework that includes protein expression data of sorted single cells. With this update we also introduce datasets broadly spanning age groups, which many users have requested, with particular interest for researchers studying paediatric leukaemias. The backend of the database has been rewritten and migrated to a cloud-based environment to accommodate the growth, and provide a better user-experience for our many international users. Users can now enjoy faster transfer speeds and a more responsive interface. In conclusion, the continuing popularity of the database and emergence of new data modalities has prompted us to rewrite and futureproof the back-end, including paediatric centric views, as well as single cell protein data, allowing us to keep the database updated and relevant for the years to come. The database is freely available at www.bloodspot.eu.
AB - BloodSpot is a specialised database integrating gene expression data from acute myeloid leukaemia (AML) patients related to blood cell development and maturation. The database and interface has helped numerous researchers and clinicians to quickly get an overview of gene expression patterns in healthy and malignant haematopoiesis. Here, we present an update to our framework that includes protein expression data of sorted single cells. With this update we also introduce datasets broadly spanning age groups, which many users have requested, with particular interest for researchers studying paediatric leukaemias. The backend of the database has been rewritten and migrated to a cloud-based environment to accommodate the growth, and provide a better user-experience for our many international users. Users can now enjoy faster transfer speeds and a more responsive interface. In conclusion, the continuing popularity of the database and emergence of new data modalities has prompted us to rewrite and futureproof the back-end, including paediatric centric views, as well as single cell protein data, allowing us to keep the database updated and relevant for the years to come. The database is freely available at www.bloodspot.eu.
U2 - 10.1093/nar/gkad993
DO - 10.1093/nar/gkad993
M3 - Journal article
C2 - 37933860
VL - 52
SP - D1138–D1142
JO - Nucleic acids symposium series
JF - Nucleic acids symposium series
SN - 0261-3166
IS - D1
ER -
ID: 374121899