Did circular DNA shape the evolution of mammalian genomes?

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Standard

Did circular DNA shape the evolution of mammalian genomes? / Holt, Sylvester; Arrey, Gerard; Regenberg, Birgitte.

In: Trends in Biochemical Sciences, Vol. 48, No. 4, 2023.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Holt, S, Arrey, G & Regenberg, B 2023, 'Did circular DNA shape the evolution of mammalian genomes?', Trends in Biochemical Sciences, vol. 48, no. 4. https://doi.org/10.1016/j.tibs.2022.09.010

APA

Holt, S., Arrey, G., & Regenberg, B. (2023). Did circular DNA shape the evolution of mammalian genomes? Trends in Biochemical Sciences, 48(4). https://doi.org/10.1016/j.tibs.2022.09.010

Vancouver

Holt S, Arrey G, Regenberg B. Did circular DNA shape the evolution of mammalian genomes? Trends in Biochemical Sciences. 2023;48(4). https://doi.org/10.1016/j.tibs.2022.09.010

Author

Holt, Sylvester ; Arrey, Gerard ; Regenberg, Birgitte. / Did circular DNA shape the evolution of mammalian genomes?. In: Trends in Biochemical Sciences. 2023 ; Vol. 48, No. 4.

Bibtex

@article{1c664dc0c36c4525a56f62f69b1a7372,
title = "Did circular DNA shape the evolution of mammalian genomes?",
abstract = "Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.",
author = "Sylvester Holt and Gerard Arrey and Birgitte Regenberg",
year = "2023",
doi = "10.1016/j.tibs.2022.09.010",
language = "English",
volume = "48",
journal = "Trends in Biochemical Sciences",
issn = "0968-0004",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Did circular DNA shape the evolution of mammalian genomes?

AU - Holt, Sylvester

AU - Arrey, Gerard

AU - Regenberg, Birgitte

PY - 2023

Y1 - 2023

N2 - Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.

AB - Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.

U2 - 10.1016/j.tibs.2022.09.010

DO - 10.1016/j.tibs.2022.09.010

M3 - Journal article

C2 - 36280496

VL - 48

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

SN - 0968-0004

IS - 4

ER -

ID: 323469109