Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking
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Nucleosome-protein complexes stick to the air-water interface and denature upon plunge freezing for cryoEM. Here, authors Chio and Palovcak et al. develop EM grids that protect such complexes and use these grids to study the ATP-dependent chromatin remodeler SNF2h.
| Original language | English |
|---|---|
| Article number | 2225 |
| Journal | Nature Communications |
| Volume | 15 |
| Issue number | 1 |
| Number of pages | 12 |
| ISSN | 2041-1723 |
| DOIs | |
| Publication status | Published - 2024 |
Bibliographical note
Publisher Copyright:
© The Author(s) 2024.
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