LongoVital in the prevention of recurrent aphthous ulceration
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LongoVital in the prevention of recurrent aphthous ulceration. / Pedersen, A; Hougen, H P; Klausen, B; Winther, K.
In: Journal of Oral Pathology & Medicine, Vol. 19, No. 8, 1990, p. 371-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - LongoVital in the prevention of recurrent aphthous ulceration
AU - Pedersen, A
AU - Hougen, H P
AU - Klausen, B
AU - Winther, K
PY - 1990
Y1 - 1990
N2 - LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during 6 months' daily intake of LV as compared with placebo in a double-blind, randomized clinical, cross-over 1-yr study. The population comprised 29 otherwise healthy minor RAU patients (18 F, 11 M), mean age 36 (18-67), with an estimated average number of recurrences the previous year of 12.8 (3-30). The number of recurrences was significantly reduced on LV the latter 4 of the 6 months (P less than 0.01) where 31% were totally free of recurrences. Subjective all-over evaluation of treatment period was significantly in favor of LV. LV induced no adverse reactions and is the first harmless systemic treatment which has proved better than placebo in the prevention of RAU.
AB - LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during 6 months' daily intake of LV as compared with placebo in a double-blind, randomized clinical, cross-over 1-yr study. The population comprised 29 otherwise healthy minor RAU patients (18 F, 11 M), mean age 36 (18-67), with an estimated average number of recurrences the previous year of 12.8 (3-30). The number of recurrences was significantly reduced on LV the latter 4 of the 6 months (P less than 0.01) where 31% were totally free of recurrences. Subjective all-over evaluation of treatment period was significantly in favor of LV. LV induced no adverse reactions and is the first harmless systemic treatment which has proved better than placebo in the prevention of RAU.
KW - Adolescent
KW - Adult
KW - Aged
KW - Binomial Distribution
KW - Double-Blind Method
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Phytotherapy
KW - Prospective Studies
KW - Recurrence
KW - Stomatitis, Aphthous
KW - Ulcer
KW - Vitamins
M3 - Journal article
C2 - 2250227
VL - 19
SP - 371
EP - 375
JO - Journal of Oral Pathology and Medicine
JF - Journal of Oral Pathology and Medicine
SN - 0904-2512
IS - 8
ER -
ID: 44355105