Neurones and neuropeptides in coelenterates

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Neurones and neuropeptides in coelenterates. / Grimmelikhuijzen, C J; Ebbesen, Ditte Graff; McFarlane, I D.

In: Archives of Histology and Cytology, Vol. 52 Suppl, 01.01.1989, p. 265-78.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Grimmelikhuijzen, CJ, Ebbesen, DG & McFarlane, ID 1989, 'Neurones and neuropeptides in coelenterates', Archives of Histology and Cytology, vol. 52 Suppl, pp. 265-78.

APA

Grimmelikhuijzen, C. J., Ebbesen, D. G., & McFarlane, I. D. (1989). Neurones and neuropeptides in coelenterates. Archives of Histology and Cytology, 52 Suppl, 265-78.

Vancouver

Grimmelikhuijzen CJ, Ebbesen DG, McFarlane ID. Neurones and neuropeptides in coelenterates. Archives of Histology and Cytology. 1989 Jan 1;52 Suppl:265-78.

Author

Grimmelikhuijzen, C J ; Ebbesen, Ditte Graff ; McFarlane, I D. / Neurones and neuropeptides in coelenterates. In: Archives of Histology and Cytology. 1989 ; Vol. 52 Suppl. pp. 265-78.

Bibtex

@article{d9832718c8d949efb58c89fbb2847578,
title = "Neurones and neuropeptides in coelenterates",
abstract = "The first nervous system probably evolved in coelenterates. Many neurons in coelenterates have morphological characteristics of both sensory and motor neurones, and appear to be multifunctional. Using immunocytochemistry with antisera to the sequence Arg-Phe-NH2 (RFamide), RFamide-like peptides were demonstrated in the nervous systems of all classes of coelenterates. Using a radioimmunoassay for RFamide, three such peptides were isolated from the sea anemone Anthopleura elegantissisma and sequenced: less than Glu-Gly-Arg-Phe-NH2 (Antho-RFamide), less than Glu-Ser-Leu-Arg-Trp-NH2 (Antho-RWamide I) and less than Glu-Gly-Leu-Arg-Trp-NH2 (Antho-RWamide II). The general structure of these peptides can be described as less than Glu...Arg-X-NH2, where X is an aromatic amino acid. From the hydromedusa Polyorchis penicillatus, the peptide less than Glu-Leu-Leu-Gly-Gly-Arg-Phe-NH2 (Pol-RFamide I) was isolated, which also belongs to the less than Glu...Arg-X-NH2 family. Using specific antisera it was shown that all four peptides were located in neurones. Application of low doses of Antho-RFamide, or Antho-RWamide I or II induced contractions of endodermal muscles of sea anemones. This indicates that these neuropeptides play a role in neurotransmission.",
keywords = "Animals, Cnidaria, Immunohistochemistry, Neurons, Neuropeptides",
author = "Grimmelikhuijzen, {C J} and Ebbesen, {Ditte Graff} and McFarlane, {I D}",
year = "1989",
month = jan,
day = "1",
language = "English",
volume = "52 Suppl",
pages = "265--78",
journal = "Archives of Histology and Cytology",
issn = "0914-9465",
publisher = "International Society of Histology and Cytology",

}

RIS

TY - JOUR

T1 - Neurones and neuropeptides in coelenterates

AU - Grimmelikhuijzen, C J

AU - Ebbesen, Ditte Graff

AU - McFarlane, I D

PY - 1989/1/1

Y1 - 1989/1/1

N2 - The first nervous system probably evolved in coelenterates. Many neurons in coelenterates have morphological characteristics of both sensory and motor neurones, and appear to be multifunctional. Using immunocytochemistry with antisera to the sequence Arg-Phe-NH2 (RFamide), RFamide-like peptides were demonstrated in the nervous systems of all classes of coelenterates. Using a radioimmunoassay for RFamide, three such peptides were isolated from the sea anemone Anthopleura elegantissisma and sequenced: less than Glu-Gly-Arg-Phe-NH2 (Antho-RFamide), less than Glu-Ser-Leu-Arg-Trp-NH2 (Antho-RWamide I) and less than Glu-Gly-Leu-Arg-Trp-NH2 (Antho-RWamide II). The general structure of these peptides can be described as less than Glu...Arg-X-NH2, where X is an aromatic amino acid. From the hydromedusa Polyorchis penicillatus, the peptide less than Glu-Leu-Leu-Gly-Gly-Arg-Phe-NH2 (Pol-RFamide I) was isolated, which also belongs to the less than Glu...Arg-X-NH2 family. Using specific antisera it was shown that all four peptides were located in neurones. Application of low doses of Antho-RFamide, or Antho-RWamide I or II induced contractions of endodermal muscles of sea anemones. This indicates that these neuropeptides play a role in neurotransmission.

AB - The first nervous system probably evolved in coelenterates. Many neurons in coelenterates have morphological characteristics of both sensory and motor neurones, and appear to be multifunctional. Using immunocytochemistry with antisera to the sequence Arg-Phe-NH2 (RFamide), RFamide-like peptides were demonstrated in the nervous systems of all classes of coelenterates. Using a radioimmunoassay for RFamide, three such peptides were isolated from the sea anemone Anthopleura elegantissisma and sequenced: less than Glu-Gly-Arg-Phe-NH2 (Antho-RFamide), less than Glu-Ser-Leu-Arg-Trp-NH2 (Antho-RWamide I) and less than Glu-Gly-Leu-Arg-Trp-NH2 (Antho-RWamide II). The general structure of these peptides can be described as less than Glu...Arg-X-NH2, where X is an aromatic amino acid. From the hydromedusa Polyorchis penicillatus, the peptide less than Glu-Leu-Leu-Gly-Gly-Arg-Phe-NH2 (Pol-RFamide I) was isolated, which also belongs to the less than Glu...Arg-X-NH2 family. Using specific antisera it was shown that all four peptides were located in neurones. Application of low doses of Antho-RFamide, or Antho-RWamide I or II induced contractions of endodermal muscles of sea anemones. This indicates that these neuropeptides play a role in neurotransmission.

KW - Animals

KW - Cnidaria

KW - Immunohistochemistry

KW - Neurons

KW - Neuropeptides

M3 - Journal article

C2 - 2573382

VL - 52 Suppl

SP - 265

EP - 278

JO - Archives of Histology and Cytology

JF - Archives of Histology and Cytology

SN - 0914-9465

ER -

ID: 33514333