No junctional communication between epithelial cells in hydra

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

No junctional communication between epithelial cells in hydra. / de Laat, S W; Tertoolen, L G; Grimmelikhuijzen, C J.

In: Nature, Vol. 288, No. 5792, 25.12.1980, p. 711-3.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

de Laat, SW, Tertoolen, LG & Grimmelikhuijzen, CJ 1980, 'No junctional communication between epithelial cells in hydra', Nature, vol. 288, no. 5792, pp. 711-3.

APA

de Laat, S. W., Tertoolen, L. G., & Grimmelikhuijzen, C. J. (1980). No junctional communication between epithelial cells in hydra. Nature, 288(5792), 711-3.

Vancouver

de Laat SW, Tertoolen LG, Grimmelikhuijzen CJ. No junctional communication between epithelial cells in hydra. Nature. 1980 Dec 25;288(5792):711-3.

Author

de Laat, S W ; Tertoolen, L G ; Grimmelikhuijzen, C J. / No junctional communication between epithelial cells in hydra. In: Nature. 1980 ; Vol. 288, No. 5792. pp. 711-3.

Bibtex

@article{c8c0fb7abb12488895df65c78dd6fb36,
title = "No junctional communication between epithelial cells in hydra",
abstract = "Diffusion gradients of morphogens have been inferred as a basis for the control of morphogenesis in hydra, and morphogenetic substances have been found which, on the basis of their molecular weight (MW), should be able to pass gap junctions. There have been several reports of the presence of gap junctions between epithelial cells of hydra. However, until now, there has been no report published on whether these junctions enable the epithelial cells to exchange molecules of small molecular weight, as has been described in other organisms. Therefore we decided to investigate the communicative properties of the junctional membranes by electrophysiological methods and by intracellular-dye iontophoresis. We report here that no electrotonic coupling is detectable between epithelial cells of Hydra attenuata in: (1) intact animals, (2) head-regenerating animals, (3) cell re-aggregates, and (4) hydra that have become nervefree. Furthermore we show that epithelial cells are unable to exchange low-molecular weight fluorescent dyes.",
keywords = "Animals, Cell Communication, Ectoderm, Electrophysiology, Endoderm, Fluorescent Dyes, Hydra, Intercellular Junctions, Membrane Potentials",
author = "{de Laat}, {S W} and Tertoolen, {L G} and Grimmelikhuijzen, {C J}",
year = "1980",
month = dec,
day = "25",
language = "English",
volume = "288",
pages = "711--3",
journal = "Nature",
issn = "0028-0836",
publisher = "nature publishing group",
number = "5792",

}

RIS

TY - JOUR

T1 - No junctional communication between epithelial cells in hydra

AU - de Laat, S W

AU - Tertoolen, L G

AU - Grimmelikhuijzen, C J

PY - 1980/12/25

Y1 - 1980/12/25

N2 - Diffusion gradients of morphogens have been inferred as a basis for the control of morphogenesis in hydra, and morphogenetic substances have been found which, on the basis of their molecular weight (MW), should be able to pass gap junctions. There have been several reports of the presence of gap junctions between epithelial cells of hydra. However, until now, there has been no report published on whether these junctions enable the epithelial cells to exchange molecules of small molecular weight, as has been described in other organisms. Therefore we decided to investigate the communicative properties of the junctional membranes by electrophysiological methods and by intracellular-dye iontophoresis. We report here that no electrotonic coupling is detectable between epithelial cells of Hydra attenuata in: (1) intact animals, (2) head-regenerating animals, (3) cell re-aggregates, and (4) hydra that have become nervefree. Furthermore we show that epithelial cells are unable to exchange low-molecular weight fluorescent dyes.

AB - Diffusion gradients of morphogens have been inferred as a basis for the control of morphogenesis in hydra, and morphogenetic substances have been found which, on the basis of their molecular weight (MW), should be able to pass gap junctions. There have been several reports of the presence of gap junctions between epithelial cells of hydra. However, until now, there has been no report published on whether these junctions enable the epithelial cells to exchange molecules of small molecular weight, as has been described in other organisms. Therefore we decided to investigate the communicative properties of the junctional membranes by electrophysiological methods and by intracellular-dye iontophoresis. We report here that no electrotonic coupling is detectable between epithelial cells of Hydra attenuata in: (1) intact animals, (2) head-regenerating animals, (3) cell re-aggregates, and (4) hydra that have become nervefree. Furthermore we show that epithelial cells are unable to exchange low-molecular weight fluorescent dyes.

KW - Animals

KW - Cell Communication

KW - Ectoderm

KW - Electrophysiology

KW - Endoderm

KW - Fluorescent Dyes

KW - Hydra

KW - Intercellular Junctions

KW - Membrane Potentials

M3 - Journal article

C2 - 7453801

VL - 288

SP - 711

EP - 713

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5792

ER -

ID: 33514936