Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease

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Standard

Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease. / Boysen, G; Boss, A H; Ødum, Niels; Olsen, J S.

In: Stroke, Vol. 15, No. 2, 1984, p. 241-3.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Boysen, G, Boss, AH, Ødum, N & Olsen, JS 1984, 'Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease', Stroke, vol. 15, no. 2, pp. 241-3.

APA

Boysen, G., Boss, A. H., Ødum, N., & Olsen, J. S. (1984). Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease. Stroke, 15(2), 241-3.

Vancouver

Boysen G, Boss AH, Ødum N, Olsen JS. Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease. Stroke. 1984;15(2):241-3.

Author

Boysen, G ; Boss, A H ; Ødum, Niels ; Olsen, J S. / Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease. In: Stroke. 1984 ; Vol. 15, No. 2. pp. 241-3.

Bibtex

@article{71711350fda511ddb219000ea68e967b,
title = "Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease",
abstract = "Platelet aggregation and bleeding time was measured in 43 cerebrovascular patients participating in a controlled double-blind study of low-dose acetylsalicylic acid. In 19 patients with satisfactory inhibition of the platelet aggregation obtained by 50 to 70 mg acetylsalicylic acid per day the bleeding time averaged 11.2 minutes in contrast to 7.0 minutes in the placebo group, p less than 0.001. This study confirms our previous findings of platelet inhibition by low-dose acetylsalicylic acid in patients with cerebrovascular disease. The prolongation of the bleeding time demonstrates that we are dealing not merely with an in vitro phenomenon but with a significant in vivo effect. The study provides the rationale for clinical evaluations of low-dose acetylsalicylic acid in stroke prophylaxis.",
author = "G Boysen and Boss, {A H} and Niels {\O}dum and Olsen, {J S}",
note = "Keywords: Aged; Aspirin; Bleeding Time; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Placebos; Platelet Aggregation; Platelet Function Tests; Random Allocation",
year = "1984",
language = "English",
volume = "15",
pages = "241--3",
journal = "Stroke",
issn = "0039-2499",
publisher = "Lippincott Williams & Wilkins",
number = "2",

}

RIS

TY - JOUR

T1 - Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease

AU - Boysen, G

AU - Boss, A H

AU - Ødum, Niels

AU - Olsen, J S

N1 - Keywords: Aged; Aspirin; Bleeding Time; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Placebos; Platelet Aggregation; Platelet Function Tests; Random Allocation

PY - 1984

Y1 - 1984

N2 - Platelet aggregation and bleeding time was measured in 43 cerebrovascular patients participating in a controlled double-blind study of low-dose acetylsalicylic acid. In 19 patients with satisfactory inhibition of the platelet aggregation obtained by 50 to 70 mg acetylsalicylic acid per day the bleeding time averaged 11.2 minutes in contrast to 7.0 minutes in the placebo group, p less than 0.001. This study confirms our previous findings of platelet inhibition by low-dose acetylsalicylic acid in patients with cerebrovascular disease. The prolongation of the bleeding time demonstrates that we are dealing not merely with an in vitro phenomenon but with a significant in vivo effect. The study provides the rationale for clinical evaluations of low-dose acetylsalicylic acid in stroke prophylaxis.

AB - Platelet aggregation and bleeding time was measured in 43 cerebrovascular patients participating in a controlled double-blind study of low-dose acetylsalicylic acid. In 19 patients with satisfactory inhibition of the platelet aggregation obtained by 50 to 70 mg acetylsalicylic acid per day the bleeding time averaged 11.2 minutes in contrast to 7.0 minutes in the placebo group, p less than 0.001. This study confirms our previous findings of platelet inhibition by low-dose acetylsalicylic acid in patients with cerebrovascular disease. The prolongation of the bleeding time demonstrates that we are dealing not merely with an in vitro phenomenon but with a significant in vivo effect. The study provides the rationale for clinical evaluations of low-dose acetylsalicylic acid in stroke prophylaxis.

M3 - Journal article

C2 - 6367153

VL - 15

SP - 241

EP - 243

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 2

ER -

ID: 10639108