- 2023
- Published
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Possible signs of recovery of the nearly extirpated Spitsbergen bowhead whales: calves observed in east Greenland
Tervo, O. M., Louis, Marie Georgette Yolande J, Sinding, Mikkel Holger Strander, Heide-Jørgensen, M. P. & Hansen, R. G., 2023, In: Polar Research. 42, 4 p., 8809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential usages of A-to-I RNA editing patterns as diagnostic biomarkers
Rodriguez Morales, D., Ilieva, M., Rennie, Sarah & Uchida, S., 2023, In: American journal of physiology. Cell physiology. 324, 4, p. C837-C842 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Probabilistic modelling in genomics
Rasmussen, Malthe Sebro, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 158 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia
Bech, J. M., Terkelsen, Thilde Bagger, Bartels, Annette Snejbjerg, Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G. I., Fang, X., Mann, Matthias & Moreira, José, 2023, In: Gastroenterology. 165, 1, p. 121-132.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets
He, Yue, Døssing, Kristina Benedikte V, Sloth, Ane Beth, He, Xuening, Rossing, Caroline Maria & Kjær, Andreas, 2023, In: Cancers. 15, 5, 16 p., 1557.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA trafficking and subcellular localization—a review of mechanisms, experimental and predictive methodologies
Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2023, In: Briefings in Bioinformatics. 24, 5, 14 p., bbad249.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid protein stability prediction using deep learning representations
Blaabjerg, Lasse Møller, Kassem, M. M., Good, L. L., Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer Enøe, Boomsma, Wouter, Stein, Amelie & Lindorff-Larsen, Kresten, 2023, In: eLife. 12, 19 p., e82593.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Redefining the Evolutionary History of the Rock Dove, Columba livia, Using Whole Genome Sequences
Hernández Alonso, Germán, Ramos Madrigal, Jazmin, van Grouw, H., Ciucani, Marta Maria, Cavill, Emily Louisa, Sinding, Mikkel Holger Strander, Gopalakrishnan, Shyam, Antunes Pacheco, George & Gilbert, M Thomas P, 2023, In: Molecular Biology and Evolution. 40, 11, 17 p., msad243.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of plant immunity via small RNA-mediated control of NLR expression
López Márquez, Diego, Del-Espino, Á., Ruiz-Albert, J., Bejarano, E. R., Brodersen, Peter & Beuzón, C. R., 2023, In: Journal of Experimental Botany. 74, 19, p. 6052-6068 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Redó-Riveiro, A., Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic Analysis of Long Non-Coding RNAs in Inflammasome Activation in Monocytes/Macrophages
Qian, N., Distefano, R., Ilieva, M., Madsen, J. H., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 5, 16 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T2DB: A Web Database for Long Non-Coding RNA Genes in Type II Diabetes
Distefano, R., Ilieva, M., Madsen, J. H., Ishii, H., Aikawa, M., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 3, 20 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The N-coil and the globular N-terminal domain of plant ARGONAUTE1 are interaction hubs for regulatory factors
Bressendorff, Simon, Kausika, S., Sjøgaard, Ida Marie Zobbe, Oksbjerg, Emilie Duus, Michels, A., Poulsen, C. & Brodersen, Peter, 2023, In: Biochemical Journal. 480, 13, p. 957-974 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs
Ciucani, M. M., Ramos-Madrigal, J., Hernández-Alonso, G., Carmagnini, A., Aninta, S. G., Sun, X., Scharff-Olsen, C. H., Lanigan, L. T., Fracasso, I., Clausen, C. G., Aspi, J., Kojola, I., Baltrūnaitė, L., Balčiauskas, L., Moore, J., Åkesson, M., Saarma, U., Hindrikson, M., Hulva, P., Bolfíková, B. Č. & 19 others, , 2023, In: iScience. 26, 8, 22 p., 107307.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The history of Coast Salish “woolly dogs” revealed by ancient genomics and Indigenous Knowledge
Lin, A. T., Hammond-Kaarremaa, L., Liu, H-L., Stantis, C., McKechnie, I., Pavel, M., Pavel, S. S. M., Wyss, S. S., Sparrow, D. Q., Carr, K., Aninta, S. G., Perri, A., Hartt, J., Bergström, A., Carmagnini, A., Charlton, S., Dalén, L., Feuerborn, T. R., France, C. A. M., Gopalakrishnan, S. & 13 others, , 2023, In: Science. 382, 6676, p. 1303-1309 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards in silico CLIP-seq: predicting protein-RNA interaction via sequence-to-signal learning
Horlacher, M., Wagner, N., Moyon, L., Kuret, K., Goedert, N., Salvatore, Marco, Ule, J., Gagneur, J., Winther, Ole & Marsico, A., 2023, In: Genome Biology. 24, 1, 37 p., 180.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards routine chromosome-scale haplotype-resolved reconstruction in cancer genomics
Garg, S., 2023, In: Nature Communications. 14, 1, 11 p., 1358.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcription factor expression is the main determinant of variability in gene co-activity
van Duin, Lucas, Krautz, Robert, Rennie, Sarah & Andersson, Robin, 2023, In: Molecular Systems Biology. 19, 7, 17 p., e11392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation
Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer learning identifies sequence determinants of cell-type specific regulatory element accessibility
Salvatore, Marco, Horlacher, M., Marsico, A., Winther, Ole & Andersson, Robin, 2023, In: NAR Genomics and Bioinformatics. 5, 2, 10 p., 026.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two Novel α-Thalassemia Mutations CD 39 -C [Thr > Pro] and CD 109 ACC > CCC [Thr > Pro] Identified in Two Chinese Families: A Case Report
Zhang, W., Han, X., Deng, J., Zhou, R., Du, X., Wu, C. & Li, M., 2023, In: Hemoglobin. 47, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncertainty-aware and explainable machine learning for early prediction of battery degradation trajectory
Rieger, L. H., Flores, E., Nielsen, K. F., Norby, P., Ayerbe, E., Winther, Ole, Vegge, T. & Bhowmik, A., 2023, In: Digital Discovery. 2, 1, p. 112-122 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unraveling the genetic basis of neurological diseases and thalassemia: the clinical utility of high throughput sequencing
ZHANG, W., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 117 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Variational Open-Domain Question Answering
Liévin, V., Motzfeldt, A. G., Jensen, I. R. & Winther, Ole, 2023, In: Proceedings of Machine Learning Research. 202, p. 20950-20977 28 p.Research output: Contribution to journal › Conference article › Research › peer-review
- 2022
- Published
Influence of Life-History Parameters on Persistent Organic Pollutant Concentrations in Blubber of Eastern North Pacific Gray Whales (Eschrichtius robustus)
Hayes, K. R. R., Ylitalo, G. M., Anderson, T. A., Urbán R, J., Jacobsen, J. K., Scordino, J. J., Lang, A. R., Baugh, K. A., Bolton, J. L., Brüniche-Olsen, Anna, Calambokidis, J., Martínez-Aguilar, S., Subbiah, S., Gribble, M. O. & Godard-Codding, C. A. J., 6 Dec 2022, In: Environmental Science and Technology. 56, 23, p. 17119-17130 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo, genome-wide profiling of endogenously tagged chromatin-binding proteins with spatial and temporal resolution using NanoDam in Drosophila
Tang, J. L. Y., Krautz, Robert, Llorà-Batlle, O., Hakes, A. E., Fox, P. M. & Brand, A. H., 2022, In: STAR Protocols. 3, 4, 30 p., 101788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene
Gramlich, S., Liu, Xiaodong, Favre, A., Buerkle, C. A. & Karrenberg, S., 2022, In: New Phytologist. 235, 4, p. 1641-1652 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A review on ethnobotany, phytochemistry, and pharmacology of the genus Didymocarpus wall. (Gesneriaceae)
Nanjala, C., Odago, W. O., Rono, P. C., Waswa, E. N., Mutinda, E. S., Oulo, M. A., Muema, F. W., Wanga, V. O., Mkala, E. M., Kuja, J., Njire, M. M. & Hu, G. W., 2022, In: Journal of Ethnopharmacology. 295, 25 p., 115404.Research output: Contribution to journal › Review › Research › peer-review
- Published
A structural biology community assessment of AlphaFold2 applications
Akdel, M., Pires, D. E., Porta Pardo, E., Jänes, J., Zalevsky, A. O., Meszaros, B., Bryant, P., Good, L. L., Laskowski, R. A., Pozzati, G., Shenoy, A., Zhu, W., Kundrotas, P., Serra, V. R., Rodrigues, C. H. M., Dunham, A. S., Burke, D., Borkakoti, N., Velankar, S., Frost, A. & 14 others, , 2022, In: Nature Structural & Molecular Biology. 29, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
African climate and geomorphology drive evolution and ghost introgression in sable antelope
Rocha, J. L., Vaz Pinto, P., Siegismund, Hans Redlef, Meyer, M., Jansen van Vuuren, B., Veríssimo, L., Ferrand, N. & Godinho, R., 2022, In: Molecular Ecology. 31, 10, p. 2968-2984 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Jørsboe, E., Andersen, M. K., Skotte, L., Stæger, F. F., Færgeman, N. J., Hanghøj, K., Santander, C. G., Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, M., Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, N., Moltke, I. & 2 others, , 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An update on principles of m6A targeting
Bai, B., 2022, In: Trends in Plant Science. 27, 3, p. 224-226 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient and historical DNA in conservation policy
Jensen, E. L., Díez-del-Molino, D., Gilbert, M Thomas P, Bertola, Laura, Borges, F., Cubric-Curik, V., de Navascués, M., Frandsen, P., Heuertz, M., Hvilsom, C., Jiménez-Mena, B., Miettinen, A., Moest, M., Chrzanová Pecnerová, Patrícia, Barnes, I. & Vernesi, C., 2022, In: Trends in Ecology and Evolution. 37, 5, p. 420-429 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Bioinformatics of transcription factor binding prediction
Navarro-Delgado, E. I., Salgado-Albarrán, M., Torres-Arciga, K., Alcaraz, N., Soto-Reyes, E., Herrera, L. A. & González-Barrios, R., 2022, Bioinformatics and Human Genomics Research. CRC Press, p. 203-221 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context
Corsi, G. I., Qu, Kunli, Alkan, F., Pan, Xiaoguang, Luo, Y. & Gorodkin, Jan, 2022, In: Nature Communications. 13, 14 p., 3006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calibrated uncertainty for molecular property prediction using ensembles of message passing neural networks
Busk, J., Jørgensen, P. B., Bhowmik, A., Schmidt, M. N., Winther, Ole & Vegge, T., 2022, In: Machine Learning: Science and Technology. 3, 1, 12 p., 015012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Is Associated With Disturbances in TCA, Lipid, and Glucose Metabolism
Hansen, C. S., Suvitaival, T., Theilade, Karen Simone, Mattila, I., Lajer, M., Trošt, K., Ahonen, L., Hansen, T. W., Legido-Quigley, C., Rossing, Peter & Ahluwalia, Tarun Veer Singh, 2022, In: Frontiers in Endocrinology. 13, 831793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
Garland, W., Müller, I., Wu, M., Schmid, M., Imamura, K., Rib, Leonor, Sandelin, Albin Gustav, Helin, K. & Jensen, T. H., 2022, In: Molecular Cell. 82, 9, p. 1691-1707.e8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromosome evolution and the genetic basis of agronomically important traits in greater yam
Bredeson, J. V., Lyons, J. B., Oniyinde, I. O., Okereke, N. R., Kolade, O., Nnabue, I., Nwadili, C. O., Hřibová, E., Parker, M., Nwogha, J., Shu, S., Carlson, J., Kariba, R., Muthemba, S., Knop, K., Barton, G. J., Sherwood, A. V., Lopez-Montes, A., Asiedu, R., Jamnadass, R. & 13 others, , 2022, In: Nature Communications. 13, 16 p., 2001.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromosome-scale haplotype-resolved pangenomics
Garg, S., Balboa, Renzo Fidel Ferdinando & Kuja, J., 2022, In: Trends in Genetics. 38, 11, p. 1103-1107 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circle-Seq reveals genomic and disease-specific hallmarks in urinary cell-free extrachromosomal circular DNAs
Lv, W., Pan, X., Han, P., Wang, Z., Feng, W., Xing, X., Wang, Q., Qu, K., Zeng, Y., Zhang, C., Xu, Z., Li, Y., Zheng, T., Lin, L., Liu, C., Liu, X., Li, H., Henriksen, R. A., Bolund, L., Lin, L. & 7 others, , 2022, In: Clinical and Translational Medicine. 12, 4, 16 p., e817.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical application of high-throughput sequencing technology in prenatal screening and diagnosis of birth defects
ZENG, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Computational identification of signals predictive for nuclear RNA exosome degradation pathway targeting
Wu, M., Schmid, M., Jensen, T. H. & Sandelin, Albin Gustav, 2022, In: NAR Genomics and Bioinformatics. 4, 3, 18 p., lqac071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conflicts between large carnivores and local pastoralists around Niokolo Koba National Park, Senegal
Gueye, M., Van Cauteren, D., Mengual, L., Pellaton, R., Leirs, H., Bertola, Laura & de Iongh, H., 2022, In: European Journal of Wildlife Research. 68, 1, 11 p., 9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Context dependency of nucleotide probabilities and variants in human DNA
Liang, Yuhu, Grønbæk, Christian, Fariselli, P. & Krogh, Anders, 2022, In: BMC Genomics. 23, 1, 15 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Context dependent prediction in DNA sequence using neural networks
Grønbæk, Christian, Liang, Yuhu, Elliott, Desmond & Krogh, Anders, 2022, In: PeerJ. 10, 22 p., e13666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contrastive learning enables rapid mapping to multimodal single-cell atlas of multimillion scale
YANG, Meng, Yang, Y., Xie, C., Ni, M., Liu, J., Yang, H., Mu, F. & Wang, J., 2022, In: Nature Machine Intelligence. 4, 8, p. 696-709 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
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Genetic diversity of lion populations in Kenya: Evaluating past management practices and recommendations for future conservation actions
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