- 2020
- Published
The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, , 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of enhancer and promoter activities of regulatory elements
Andersson, Robin & Sandelin, Albin Gustav, 2020, In: Nature Reviews Genetics. 21, 2, p. 71-87 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Occurrence and Functions of m6A and Other Covalent Modifications in Plant mRNA
Arribas Hernandez, Laura & Brodersen, Peter, 2020, In: Plant Physiology. 182, 1, p. 79-96 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recurrent requirement for the m6A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis
Arribas Hernandez, Laura, Simonini, S., Hansen, M. H., Botterweg Paredes, E., Bressendorff, Simon, Dong, Y., Østergaard, L. & Brodersen, Peter, 2020, In: Development. 147, 14, 19 p., dev189134.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating narrow-sense heritability using family data from admixed populations
Athanasiadis, G., Speed, D., Lepola, Mette Andersen, Appel, E. V. R., Grarup, Niels, Brandslund, I., Jørgensen, M. E., Larsen, C. V. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: Heredity. 124, 6, p. 751-762 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial
Lange, Jette Bornholdt, Chen, Y., Rago, Alfredo, Sloth, S., Hendel, J., Melsæther, C., Müller, C. V., Juul Nielsen, M., Strickertsson, J., Engelholm, Lars Henning, Vitting-Seerup, K., Jensen, Kim Bak, Baker, A. & Sandelin, Albin Gustav, 9 Nov 2020, In: Gut Microbes. 12, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Daily estimates of clinical severity of symptoms in bipolar disorder from smartphone-based self-assessments
Busk, J., Faurholt-Jepsen, M., Frost, M., Bardram, J. E., Kessing, Lars Vedel & Winther, Ole, 2020, In: Translational Psychiatry. 10, 12 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forecasting Mood in Bipolar Disorder From Smartphone Self-assessments: Hierarchical Bayesian Approach
Busk, J., Faurholt-Jepsen, M., Frost, M., Bardram, J. E., Kessing, Lars Vedel & Winther, Ole, 1 Apr 2020, In: JMIR mHealth and uHealth. 8, 4, 14 p., e15028.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China
Cai, Y., Fu, W., Cai, D., Heller, R., Zheng, Z., Wen, J., Li, H., Wang, X., Alshawi, A., Sun, Z., Zhu, S., Wang, J., Yang, M., Hu, S., Li, Y., Yang, Z., Gong, M., Hou, Y., Lan, T., Wu, K. & 3 others, , 2020, In: Molecular Biology and Evolution. 37, 7, p. 2099-2109 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation
Bjørnkjær, Lene, Stein, Amelie, Grønbæk-Thygesen, Martin, Nygaard, L., Søltoft, C. L., Nielsen, S. V., Lisby, Michael, Ravid, T., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: PLOS Genetics. 16, 11, 28 p., e1009187.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent insights on indirect mechanisms in developmental toxicity of nanomaterials
Dugershaw, B. B., Aengenheister, L., Hansen, Signe Schmidt Kjølner, Hougaard, Karin Sørig & Buerki-Thurnherr, T., 2020, In: Particle and Fibre Toxicology. 17, 22 p., 31.Research output: Contribution to journal › Review › Research › peer-review
- Published
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets
Feuerborn, Tatiana Richtman, Palkopoulou, E., van der Valk, T., von Seth, J., Munters, A. R., Chrzanová Pecnerová, Patrícia, Dehasque, M., Ureña, I., Ersmark, E., Lagerholm, V. K., Krzewinska, M., Rodríguez-Varela, R., Götherström, A., Dalén, L. & Díez-del-Molino, D., 2020, In: BMC Genomics. 21, 10 p., 844.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JASPAR 2020: update of the open-access database of transcription factor binding profiles
Fornes, O., Castro-Mondragon, J. A., Khan, A., van der Lee, R., Zhang, X., Richmond, P. A., Modi, B. P., Correard, S., Gheorghe, M., Baranašić, D., Santana-Garcia, W., Tan, G., Chèneby, J., Ballester, B., Parcy, F., Sandelin, Albin Gustav, Lenhard, B., Wasserman, W. W. & Mathelier, A., 2020, In: Nucleic Acids Research. 48, D1, p. D87-D92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted conservation genetics of the endangered chimpanzee
Frandsen, P., Fontsere, C., Nielsen, S. V., Hanghøj, Kristian Ebbesen, Castejon-Fernandez, N., Lizano, E., Hughes, D., Hernandez-Rodriguez, J., Korneliussen, Thorfinn Sand, Carlsen, F., Siegismund, Hans Redlef, Mailund, T., Marques-Bonet, T. & Hvilsom, C., 2020, In: Heredity. 125, 1-2, p. 15-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of model fit of inferred admixture proportions
Garcia Erill, Genís & Albrechtsen, Anders, 2020, In: Molecular Ecology Resources. 20, 4, p. 936-949Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1
Gazova, I., Lefevre, L., Bush, S. J., Clohisey, S., Arner, E., de Hoon, M., Severin, J., van Duin, Lucas, Andersson, Robin, Lengeling, A., Hume, D. A. & Summers, K. M., 2020, In: Frontiers in Cell and Developmental Biology. 8, 21 p., 498.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
scVAE: variational auto-encoders for single-cell gene expression data
Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GISA: using Gauss Integrals to identify rare conformations in protein structures
Grønbæk, Christian, Hamelryck, Thomas Wim & Røgen, P., 2020, In: PeerJ. 8, 16 p., e9159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sinonasal cancer
Husgafvel-Pursiainen, K., Carton, M., Luce, D., Wolff, H., Holmila, R., Schlünssen, V., Lange, Jette Bornholdt & Hansen, J., 2020, Occupational Cancers. Anttila, S. & Boffetta, P. (eds.). 2. ed. ed. Springer, p. 147-178 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Community curation of bioinformatics software and data resources
Ison, J., Ménager, H., Brancotte, B., Jaaniso, E., Salumets, A., Raček, T., Lamprecht, A. L., Palmblad, M., Kalaš, M., Chmura, Piotr Jaroslaw, Hancock, J. M., Schwämmle, V. & Ienasescu, H. I., 2020, In: Briefings in Bioinformatics. 21, 5, p. 1697-1705 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classifying disease-associated variants using measures of protein activity and stability
Jepsen, M. M., Fowler, D. M., Hartmann-Petersen, Rasmus, Stein, Amelie & Lindorff-Larsen, Kresten, 2020, Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Pey, A. L. (ed.). Elsevier, p. 91-107Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome
Karstensen, H. G., Rendtorff, N. D., Hindbæk, L. S., Colombo, R., Stein, Amelie, Birkebæk, N. H., Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Højland, A. T., Petersen, M. B. & Tranebjærg, Lisbeth, 2020, In: European Journal of Medical Genetics. 63, 3, 6 p., 103733.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic architecture of sporadic and multiple consecutive miscarriage
Laisk, T., Soares, A. L. G., Ferreira, T., Painter, J. N., Censin, J. C., Laber, S., Bacelis, J., Chen, C. Y., Lepamets, M., Lin, K., Liu, S., Millwood, I. Y., Ramu, A., Southcombe, J., Andersen, M. S., Yang, L., Becker, C. M., Børglum, A. D., Gordon, S. D., Bybjerg-Grauholm, J. & 35 others, , 2020, In: Nature Communications. 11, 5980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
24 Messages on a Sustainable Career in Research at UCPH
Larsen, K. R. (ed.), Wegener, H. C., Stein, A., Bach, A., Williams, A. R., Gall, C., Gravert, C., Gloriam, D. E., Lorenzen, E., Yvanez, E., Cappellini, E., Poulsen, F., Mortensen, J., Bentzen, J. S., Shik, J. Z., Miskowiak, K. W., Elgaard, K. K. E., Jønsson, K. A., Won, K. J., Nørgaard, L. C. & 9 others, , 2020, University of Copenhagen. 31 p.Research output: Book/Report › Report › Communication
- Published
Organismal benefits of transcription speed control at gene boundaries
Leng, Xueyuan, Ivanov, M., Kindgren, P., Malik, I., Thieffry, A., Brodersen, Peter, Sandelin, Albin Gustav, Kaplan, C. D. & Marquardt, Sebastian, 2020, In: EMBO Reports. 21, 4, 16 p., e49315.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of ultrasonography on identifying noninvasive prenatal screening false-negative aneuploidy
Li, W., Zeng, F., Fan, B., Yu, N., Wu, J., Yang, Y., Huang, H., Li, S. & Peng, Z., 2020, In: Molecular genetics & genomic medicine. 8, 6, 7 p., e1213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Targeted Multiomics Approach to Identify Biomarkers Associated with Rapid eGFR Decline in Type 1 Diabetes
Limonte, C. P., Valo, E., Montemayor, D., Afshinnia, F., Ahluwalia, T. S., Costacou, T., Darshi, M., Forsblom, C., Hoofnagle, A. N., Groop, P-H., Miller, R. G., Orchard, T. J., Pennathur, S., Rossing, P., Sandholm, N., Snell-Bergeon, J. K., Ye, H., Zhang, J., Natarajan, L., De Boer, I. H. & 1 others, , 2020, In: American Journal of Nephrology. 51, 10, p. 839-848 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De Novo Pathway-Based Classification of Breast Cancer Subtypes
List, M., Alcaraz, N. & Batra, R., 2020, Protein-Protein Interaction Networks: Methods and Protocols. Canzar, S. & Ringeling, F. R. (eds.). Humana Press, p. 201-213 13 p. (Methods in Molecular Biology, Vol. 2074).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Optimal Variance Control of the Score-Function Gradient Estimator for Importance Weighted Bounds
Liévin, V., Dittadi, A., Christensen, Anders & Winther, Ole, 2020, In: Advances in Neural Information Processing Systems. 2020-December, 12 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Population genomics of the Viking world: [incl. correction]
Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, , 2020, In: Nature. 585, 7825, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic mRNPs revisited: Singletons and condensates
Mateu-Regue, A., Nielsen, Finn Cilius & Christiansen, Jan, 2020, In: BioEssays. 42, 12, 13 p., 2000097.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Method Development for Next-Generation Sequencing Data in Population Genetics
Meisner, Jonas, 2020, Department of Biology, Faculty of Science, University of Copenhagen. 154 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data
Moreno-Mayar, J. V., Korneliussen, Thorfinn Sand, Dalal, J., Renaud, Gabriel, Albrechtsen, Anders, Nielsen, Rasmus & Malaspinas, A., 2020, In: Bioinformatics. 36, 3, p. 828-841 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bayesian protein superposition using Hamiltonian Monte Carlo
Sanz Moreta, Lys, Al-Sibahi, A. S. & Hamelryck, Thomas Wim, Oct 2020, Proceedings - IEEE 20th International Conference on Bioinformatics and Bioengineering, BIBE 2020. IEEE, p. 1-11 9288019Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
An RNAi independent antiviral activity of the Arabidopsis thaliana DCL2
Nielsen, C. P. S., 2020, Department of Biology, Faculty of Science, University of Copenhagen. 104 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Protein destabilization and degradation as a mechanism for hereditary disease
Nielsen, S. V., Schenstrøm, S. M., Christensen, Caspar Elo, Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Pey, A. L. (ed.). Elsevier, p. 111-125Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
Obara, E. A. A., Aguilar-Morante, D., Rasmussen, R. D., Frias, A., Vitting-Serup, K., Lim, Y. C., Elbæk, K. J., Pedersen, H., Vardouli, L., Jensen, K. E., Skjoth-Rasmussen, J., Brennum, J., Tuckova, L., Strauss, R., Dinant, C., Bartek, J. & Hamerlik, P., 2020, In: Nature Communications. 11, 14 p., 4709.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]
Orengo, C., Velankar, S., Wodak, S., Zoete, V., Bonvin, A. M. J. J., Elofsson, A., Feenstra, K. A., Gerloff, D. L., Hamelryck, T., Hancock, J. M., Helmer-Citterich, M., Hospital, A., Orozco, M., Perrakis, A., Rarey, M., Soares, C., Sussman, J. L., Thornton, J. M., Tuffery, P., Tusnady, G. & 3 others, , 2020, In: F1000Research. 9, 27 p., 278.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells
Pedersen, H., Obara, E. A. A., Elbæk, K. J., Vitting-Serup, K. & Hamerlik, P., 2020, In: International Journal of Molecular Sciences. 21, 5, 13 p., 1588.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools
Prachar, Marek, Justesen, S., Steen-Jensen, D. B., Thorgrimsen, S., Jurgons, E., Winther, Ole & Bagger, F. O., 2020, In: Scientific Reports. 10, 8 p., 20465.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional annotation of human long noncoding RNAs via molecular phenotyping
Ramilowski, J. A., Yip, C. W., Agrawal, S., Chang, J-C., Ciani, Y., Kulakovskiy, I. V., Mendez, M., Ooi, J. L. C., Ouyang, J. F., Parkinson, N., Petri, A., Roos, L., Severin, J., Yasuzawa, K., Abugessaisa, I., Akalin, A., Antonov, I. V., Arner, E., Bonetti, A., Bono, H. & 96 others, , 2020, In: Genome Research. 30, 7, p. 1060-1072 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary Study of the Crassphage Virus at Gene Level
Rossi, A., Treu, L., Toppo, S., Zschach, Henrike, Campanaro, S. & Dutilh, B. E., 2020, In: Viruses. 12, 9, 13 p., 1035.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet
Senftleber, N., Jørgensen, M. E., Jørsboe, E., Imamura, F., Forouhi, N. G., Larsen, C. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: European Journal of Human Genetics. 28, 11, p. 1592-1601 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Omega-3 fatty acids and risk of cardiovascular disease in Inuit: First prospective cohort study
Senftleber, N. K., Albrechtsen, Anders, Lauritzen, Lotte, Larsen, C. L., Bjerregaard, P., Diaz, L. J., Rønn, P. F. & Jørgensen, M. E., 2020, In: Atherosclerosis. 312, p. 28-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The traditional diet and genetic architecture of the Greenlandic Inuit and their cardiovascular effects
Senftleber, N. K., 2020, Department of Biology, Faculty of Science, University of Copenhagen. 163 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Lactobacillus rhamnosus GG Genomic and Phenotypic Stability in an Industrial Production Process
Strickertsson, Marianne Stage, Wichmann, A., Jørgensen, M., Vera-Jimenéz, N. I., Wielje, M., Nielsen, Dennis Sandris, Sandelin, Albin Gustav, Chen, Y. & Baker, A., 2020, In: Applied and Environmental Microbiology. 86, 6, 15 p., e02780-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Scramble-in: A fast and efficient method to diversify and improve the yields of heterologous pathways in synthetic yeast
Swidah, R., Auxillos, Jamie Yam, Liu, W., Jones, S., Chan, T. F., Dai, J. & Cai, Y., 2020, Methods in Molecular Biology. Humana Press, p. 305-327 23 p. (Methods in Molecular Biology, Vol. 2205).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Detection of Viable and Total Bacterial Community in the Pit Mud of Chinese Strong-Flavor Liquor Using Propidium Monoazide Combined With Quantitative PCR and 16S rRNA Gene Sequencing
Tan, G., Zhou, R., Zhang, W., Hu, Y., Ruan, Z., Li, J., Zhang, C., Shen, D., Peng, N., Liang, Y. & Zhao, S., 2020, In: Frontiers in Microbiology. 11, 9 p., 896.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CAncer bioMarker Prediction Pipeline (CAMPP) - A standardized framework for the analysis of quantitative biological data
Terkelsen, T., Krogh, Anders & Papaleo, E., 2020, In: PLOS Computational Biology. 16, 3, 20 p., e1007665.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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