EMBARQ: Evaluating Microbiome Based Applications for Risk Quantification

Quantifying the impact of Biologicals. We assess the safety of biologicals for agriculture, sustainability and biodiversity.

 

EMBARQ's primary purpose is to provide a knowledge base and develop innovative tools for quantifying the impact of these organisms, facilitating rapid assessment methods for industry and regulators.

The project proposes four novel aspects for risk assessment: tracking biologicals in the environment, calibrating risks against natural fluctuations, integrating AI tools for risk assessment, and considering a OneHealth perspective.

EMBARQ will expand traditional risk assessment steps to cover various risk factors, e.g., how horizontal gene transfer may affect pathogenicity, and assess environmental impacts.

 

 

Quantifying safety of Biologicals

EMBARQ researchers at Aarhus and Copenhagen universities will track biologicals and microbial behaviour

EMBARQ will develop a one health based hazard assessment at the Statens Serum Institute in Copenhagen

Environmental hazard assessment will be expanded to European scales using AI driven tools at Aalborg University Denmark

EMBARQ will address chemical risks associated with bioinoculants in agriculture and bioremediation at Aarhus University.

This interdisciplinary effort ensures EMBARQ’s risk assessments align with both EU and national regulatory priorities, supporting sustainable and safe soil management.

 

 

UCPH hosts CoDoN
EMBARQ shares facilities such as cell sorting and sequencing with the CoDoN - Copenhagen DNA analysis center.

Environmental Science
EMBARQ will track biologicals in the environment from the Department of Environmental Sciences Roskilde Denmark

Protection from threats
The Statens Serum Institute helps protect agains infectious disease and biological threats

Future proofing with AI bioscience
Environmental AI research based bioscience to protect our future is conducted the institute for Chemistry and Bioscience

 

 

The research project aims to quantify the impact of biological use, track biologicals in the environment using AI, and build a risk assessment framework to enhance safety, sustainability, biodiversity, and ecosystem services.

  1. Hazard assessment
    EMBARQ will gather relevant data on factors such as horizontal gene transfer or key microbes.

  2. Microcosm experiments
    EMBARQ will use methods such as metagenomics to investigate effects of perturbation and large scale variation.

  3. In silico validation
    EMBARQ will investigate geographic and climatic variation using AI and bioinformatic big data.

  4. Field trials
    EMBARQ will investigate bioprotection and bioremediation with meta-genomics, transcriptomics and metabolomics.

  5. Chemical analysis
    EMBARQ will employ advanced techniques to provide chemical analyses of metabolites, toxins, and by-products from bioinoculants. They will be combined with in silico tools for hazard and risk screenings.

  6. Impact
    EMBARQ will develop recommendations based on research findings to support safer and more sustainable practices.

 

  

 

Søren Sørensen

Project leader

Søren J. Sørensen
Professor

Phone +45 51 82 70 07
sjs@bio.ku.dk

Supported by

Novo Nordisk Foundation logo

EMBARQ is funded by the Novo Nordisk Foundation for the period 2024–2030 and brings together partners from the University of Copenhagen, Aarhus University, Aalborg University, and the Statens Serum Institut.