Publications from

Total publications from unit:

2024

1.

 Anders Lønstrup Hansen, Frederik Friis Theisen, Ramon Crehuet, Enrique Marcos, Nushin Aghajari and Martin Willemoës. (2024) Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination ACS Synthetic Biology 13(3):862-875.

2022

2.

 Dennis K. Hansen, Anders Lønstrup Hansen, Johanna M. Koivisto, Bashar Shuoker, Maher Abou Hachem, Jakob R. Winther and Martin Willemoës. (2022) Engineering Bifidobacterium longum Endo-a-N-acetylgalactosaminidase for Neu5Aca2-3Ga1ß1-3Ga1NAc reactivity on Fetuin Archives of Biochemistry and Biophysics 725.

3.

 Johanna Maarit Koivisto, Nina Rødtness Poulsen, Benedikte Stoklund Larsen, M. G. M. Weibull, Amelie Stein, Fabio Doro, Jakob Rahr Winther, Kresten Lindorff-Larsen and Martin Willemoës. (2022) Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system The Biochemical journal 479(4):479-501.

2021

4.

 Anders Lønstrup Hansen, Johanna M. Koivisto, Signe Simonsen, Zehui Dong, Ramon Crehuet, Dennis K. Hansen and Martin Willemoës. (2021) Identification of a Catalytic Nucleophile-Activating Network in the endo-a-N-Acetylgalactosaminidase of Family GH101 Biochemistry 60(45):3398-3407.

5.

 Fenne Marjolein Dijkema, Matilde Knapkøien Nordentoft, Anders Krøll Didriksen, Anders Sværke Corneliussen, Martin Willemoës and Jakob R. Winther. (2021) Flash properties of Gaussia luciferase are the result of covalent inhibition after a limited number of cycles Protein Science 30(3):638-649.

6.

 Frederik Friis Theisen, Lasse Staby, Frederik Grønbæk Tidemand, Charlotte O'Shea, Andreas Prestel, Martin Willemoës, Birthe B. Kragelund and Karen Skriver. (2021) Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding Journal of the American Chemical Society 143(36):14540-14550.

7.

 Sarah K. Gersing, Yong Wang, Martin Grønbæk-Thygesen, Caroline Kampmeyer, Lene Clausen, Martin Willemoës, Claes Andréasson, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2021) Mapping the degradation pathway of a disease-linked aspartoacylase variant PLOS Genetics 17(4).

2020

8.

 Louise Hamborg, Emma Wenzel Horsted, Kristoffer Enøe Johansson, Martin Willemoës, Kresten Lindorff-Larsen and Kaare Teilum. (2020) Global analysis of protein stability by temperature and chemical denaturation Analytical Biochemistry 605.

2019

9.

 Benjamin Bjerre, Jakob Nissen, Mikkel Madsen, Jurate Kamarauskaite, Rasmus K Norrild, Peter C Holm, Mathilde K Nordentoft, Charlotte O'Shea, Martin Willemoës, Kristoffer E Johansson and Jakob R Winther. (2019) Improving folding properties of computationally designed proteins Protein Engineering Design and Selection (Print) 32(3):145-151.

10.

 Andreas Prestel, Nanna Wichmann, Joao M. Martins, Riccardo Marabini, Noah Kassem, Sebastian S. Broendum, Marit Otterlei, Olaf Nielsen, Martin Willemoës, Michael Ploug, Wouter Boomsma and Birthe B. Kragelund. (2019) The PCNA interaction motifs revisited: thinking outside the PIP-box Cellular and Molecular Life Sciences 76(24):4923-4943.

11.

 Dennis K. Hansen, Jakob R. Winther and Martin Willemoës. (2019) Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-a-N-acetylgalactosaminidase Carbohydrate Research 480:54-60.

12.

 Niels Hadrup, Kristina Bram Knudsen, Trine Berthing, Henrik Wolff, Stefan Bengtson, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob Rahr Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Harri Alenius, Hannu Norppa, Håkan Wallin and Ulla Vogel. (2019) Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses Environmental Toxicology and Pharmacology 66:116-125.

2018

13.

 Marit Ilves, Sara Vilske, Kukka Aimonen, Hanna K. Lindberg, Saila Pesonen, Irene Wedin, Markus Nuopponen, Esa Vanhala, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel, Henrik Wolff, Hannu Norppa, Kai Savolainen and Harri Alenius. (2018) Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month Nanotoxicology 12(7):729-746.

14.

 Paul Santner, Joao Miguel da Silva Martins, Caroline Kampmeyer, Rasmus Hartmann-Petersen, Jonas S. Laursen, Amelie Stein, Christian A Olsen, Isaiah T Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants Biochemistry 57(41):5957-5968.

15.

 Paul Santner, João Miguel da Silva Martins, Jonas S. Laursen, Lars Behrendt, Leise Riber, Christian A Olsen, Isaiah T. Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel Biochemistry 57(41):5949-5956.

2017

16.

 Lasse Staby, Charlotte O'Shea, Martin Willemoës, Frederik Theisen, Birthe Brandt Kragelund and Karen Skriver. (2017) Eukaryotic transcription factors: paradigms of protein intrinsic disorder Biochemical Journal 474(15):2509-2532.

17.

 Sirke Virkkunen, Henrik Wolff, Caj Haglund, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel and Jaana Hagström. (2017) Positive staining for cellulose in oral pulse granuloma Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 123(4):464-467.

18.

 Bjarne Hove-Jensen, Kasper R. Andersen, Mogens Kilstrup, Jan Martinussen, Robert L. Switzer and Martin Willemoës. (2017) Phosphoribosyl diphosphate (PRPP): biosynthesis, enzymology, utilization, and metabolic significance Microbiology and Molecular Biology Reviews 81(1).

19.

 Charlotte O'Shea, Lasse Staby, Sidsel Krogh Bendsen, Frederik Grønbæk Tidemand, Andreas Redsted, Martin Willemoës, Birthe Brandt Kragelund and Karen Skriver. (2017) Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1 Journal of Biological Chemistry 292(2):512-527.

20.

 Julia Catalán, Elina Rydman, Kukka Aimonen, Kati-Susanna Hannukainen, Satu Suhonen, Esa Vanhala, Carlos Moreno, Valérie Meyer, Denilson da Silva Perez, Asko Sneck, Ulla Forsström, Casper Højgaard, Martin Willemoës, Jacob R. Winther, Ulla Vogel, Henrik Wolff, Harri Alenius, Kai M. Savolainen and Hannu Norppa. (2017) Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs Mutagenesis 32(1):23-31.

2016

21.

 Casper Højgaard, Christian Kofoed, Roall Espersen, Kristoffer Enøe Johansson, Mara Villa, Martin Willemoës, Kresten Lindorff-Larsen, Kaare Teilum and Jakob R. Winther. (2016) A soluble, folded protein without charged amino acid residues Biochemistry 55(28):3949–3956.

22.

 Kristoffer Enøe Johansson, Nicolai Tidemand Johansen, Signe Christensen, Scott Horowitz, James C. A. Bardwell, Johan Gotthardt Olsen, Martin Willemoës, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck and Jakob R. Winther. (2016) Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template Journal of Molecular Biology 428(21):4361-4377.

2015

23.

 Charlotte O'Shea, Mikael Kryger Jensen, Emil G.P. Stender, Birthe Brandt Kragelund, Martin Willemoës and Karen Skriver. (2015) Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1 Biochemical Journal 465(2):281-294.

24.

 Christian Berg Oehlenschlæger, Monika Nøhr Løvgreen, Eva Reinauer, Emilia Lehtinen, Marie-Louise Lindberg Pind, Pernille Harris, Jan Martinussen and Martin Willemoës. (2015) Bacillus halodurans strain C125 encodes and synthesizes enzymes from both known pathways to form dUMP directly from Cytosine Deoxyribonucleotides Applied and Environmental Microbiology 81(10):3395-3404.

25.

 Dennis Hansen, Helen Webb, Jonas Willum Nielsen, Pernille Harris, Jakob R. Winther and Martin Willemoës. (2015) Mutational analysis of divalent metal ion binding in the active site of class II a-mannosidase from Sulfolobus solfataricus Biochemistry 54(11):2032-2039.

26.

 Kristina Bram Knudsen, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Sara Vilske, Kukka Aimonen, Ingrid Elise Konow Weydahl, Harri Alenius, Hannu Norppa, Henrik Wolff, Erik Håkan Richard Wallin and Ulla Vogel. (2015) Visualization of nanofibrillar cellulose in biological tissues using a biotinylated carbohydrate binding module of ß-1,4-Glycanase Chemical Research in Toxicology 28(8):1627-1635.

2014

27.

 Darrell Cockburn, Casper Wilkens, Christian Ruzanski, Susan Andersen, Jonas Willum Nielsen, Alison M. Smith, Robert A. Field, Martin Willemoës, Maher Abou Hachem and Birte Svensson. (2014) Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review Biologia 69(6):705-712.

28.

 Jan Halborg Jensen, Martin Willemoës, Jakob R. Winther and Luca De Vico. (2014) In Silico prediction of mutant HIV-1 proteases cleaving a target sequence P L o S One 9(5).

29.

 Michael Riis Hansen, Eric W. Barr, Kaj Frank Jensen, Martin Willemoës, Charles Grubmeyer and Jakob R. Winther. (2014) Catalytic site interactions in yeast OMP synthase Archives of Biochemistry and Biophysics 542:28-38.

2013

30.

 Marie S. Møller, Darrell Cockburn, Jonas W. Nielsen, Johanne M. Jensen, Malene B. Vester-christensen, Morten M. Nielsen, Joakim M. Andersen, Casper Wilkens, Julie Rannes, Per Hägglund, Anette Henriksen, Maher Abou Hachem, Martin Willemoës and Birte Svensson. (2013) Surface Binding Sites (SBSs), Mechanism and Regulation of Enzymes Degrading Amylopectin and a-Limit Dextrins Journal of Applied Glycoscience 60(2):101-109.

2012

31.

 Jonas Willum Nielsen, Birte Kramhøft, Sophie Bozonnet, Maher Abou Hachem, Susan Louise Svane Stipp, Birte Svensson and Martin Willemoës. (2012) Degradation of the starch components amylopectin and amylose by barley a-amylase 1: role of surface binding site 2 Archives of Biochemistry and Biophysics 528(1):1-6.

32.

 Jonas Willum Nielsen, Karina Krarup Sand, Christian Schack Pedersen, L. Z. Lakshtanov, Jakob R. Winther, Martin Willemoës and Susan Louise Svane Stipp. (2012) Polysaccharide effects on calcite growth: the influence of composition and branching Crystal Growth & Design 12(10):4906-4910.

33.

 Jonas Willum Nielsen, Nina Rødtness Poulsen, Anna Margit Susanne Johnsson, Jakob R. Winther, Susan Louise Svane Stipp and Martin Willemoës. (2012) Metal-ion dependent catalytic properties of Sulfolobus solfataricus class II a-mannosidase Biochemistry 51(40):8039-8046.

2011

34.

 Jan Martinussen, Martin Willemoës and Mogens Kilstrup. (2011) The Biochemical Basis | Nucleotide Metabolism Comprehensive Biotechnology. 1:91-107.

35.

 Iben H. Lauritsen, Martin Willemoës, Kaj Frank Jensen, Eva Johansson and Pernille Harris. (2011) Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 67(2):201-208.

2010

36.

 Bjarne Hove-Jensen, Tina J. Rosenkrantz, David L. Zechel and Martin Willemoës. (2010) Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli Journal of Bacteriology 192(1):370-374.

2009

37.

 Julie H B Siggaard, Eva Johansson, Tina Reinholdt Vognsen, Signe Smedegaard Helt, Pernille Harris, Sine Larsen and Martin Willemoës. (2009) Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis Archives of Biochemistry and Biophysics 490(1):42-9.

38.

 Stig Christoffersen, Anders Kadziola, Eva Johansson, Michael Rasmussen, Martin Willemoës and Kaj Frank Jensen. (2009) Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus Journal of Molecular Biology 393(2):464-477.

2008

39.

 Kaj Frank Jensen, Gert Dandanell, Bjarne Hove-Jensen and Martin Willemoës. (2008) Nucleotides, Nucleosides, and Nucleobases EcoSal. Escherichia coli and Salmonella: cellular and molecular biology.

40.

 M. M. Nielsen, E. S. Seo, A. Dilokpimol, J. Andersen, M. Abou Hachem, H. Naested, Martin Willemoës, S. Bozonnet, L. Kandra, G. Gymnt, R. Haser, N. Aghajari and B. Svensson. (2008) Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates Biocatalysis and Biotransformation 26:59-67.

41.

 Signe Smedegaard Helt, Majbritt Thymark, Pernille Harris, Claus Aagaard, Jes Dietrich, Sine Larsen and Martin Willemoes. (2008) Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis Journal of Molecular Biology 376(2):554-69.

2007

42.

 Eva Johansson, Majbritt Thymark, Julie H Bynck, Mathias Fanø, Sine Larsen and Martin Willemoës. (2007) Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme FEBS Journal 274(16):4188-4198.

43.

 Majbritt Thymark, Eva Johansson, Sine Larsen and Martin Willemoës. (2007) Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase Archives of Biochemistry and Biophysics 470(1):20-6.

44.

 Sophie Bozonnet, Morten Tovborg Jensen, Morten Munch Nielsen, Nushin Aghajari, Malene H. Jensen, Birte Kramhøft, Martin Willemoës, Samuel Tanier, Richard Haser and Birte Svensson. (2007) The pair of sugar tongs site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity FEBS Journal 274:5055-5067.

2006

45.

 Heidi Asschenfeldt Ernst, Leila Lo Leggio, M. Willemoes, G. A. Leonard, P. Blum and Sine Larsen. (2006) Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31 Journal of Molecular Biology 358(4):1106-24.

46.

 M. ABou Hachem, S. Bozonnet, M. Willemoes, B. Kramhøft, K. Fukuda, Birgit C. Bønsager, M. T. Jensen, J. Nøhr, N. Tranier, N.. Juge, x. Robert, Richard Haser, N. Aghajari and B. Svensson. (2006) Interactions of barley alpha-amylase isozymes with Ca2+, substrates and proteinaceous inhibitors Biocatalysis and Biotransformation 24:83-93.

47.

 Maher Abou Hachem, Sophie Bozonnet, Martin Willemoës, Birgit C. Bønsager, Morten Munch Nielsen, Kenji Fukuda, Birte Kramhøft, Kenji Maeda, Bent Walther Sigurskjold, Per Hägglund, Christine Finnie, Haruhide Mori, Xavier Robert, Malene H. Jensen, Samuel Tranier, Nushin Aghajari, Richard Haser and Birte Svensson. (2006) Interactions between Barley a-Amylases, Substrates, Inhibitors and Regulatory Proteins Journal of Applied Glycoscience 53(2):163-169.

48.

 Maher Abou Hachem, Sophie Bozonnet, Martin Willemoës, Birgit C. Bønsager, Morten Munch Nielsen, Kenji Fukuda, Birte Kramhøft, Kenji Maeda, Bent W. Sigurskjold, Per Hägglund, Christine Finnie, Haruhide Mori, Xavier Robert, Malene H. Jensen, Samuel Tranier, Nushin Aghajari, Richard Haser and Birte Svensson. (2006) Interactions between Barley a-Amylases, Substrates, Inhibitors and Regulatory Proteins Journal of Applied Glycoscience 53(2):163-169.

2005

49.

 Eva Johansson, Mathias Fanø, Julie H Bynck, Jan Neuhard, Sine Larsen, Bent W Sigurskjold, Ulla Christensen and Martin Willemoës. (2005) Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes Journal of Biological Chemistry 280(4):3051-9.

50.

 Heidi Asschenfeldt Ernst, Martin Willemoës, Leila Lo Leggio, Gordon Leonard, Paul Blum and Sine Larsen. (2005) Characterization of different crystal forms of the a-glucosidase MalA from Sulfolobus solfataricus Acta Crystallographica Section F 61:1039-1042.

51.

 Heidi Asschenfeldt Ernst, Martin Willemoës, Leila Lo Leggio, Gordon Leonard, Paul Blum and Sine Larsen. (2005) Characterization of different crystal forms of the alpha-glucosidase MalA from Sulfolobus solfataricus Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 61:1039-42.

52.

 Martin Willemoes and M. Kilstrup. (2005) Nucleoside triphosphate synthesis catalysed by adenylate kinase is ADP dependent Archives of Biochemistry and Biophysics 444(2):195-199.

53.

 Martin Willemoës, Anne Mølgaard, Eva Helena Johansson and Jan Martinussen. (2005) Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity FEBS Journal 272(3):856-864.

54.

 Sophie Bozonnet, Birgit C. Bønsager, Birte Kramhøft, Haruhide Mori, Maher Abou Hachem, Martin Willemoës, Morten T. Jensen, Kenji Fukuda, Peter K. Nielsen, Nathalie Juge, Nushin Aghajari, Samuel Tranier, Xavier Robert, Richard Haser and Birte Svensson. (2005) Binding of carbohydrates and protein inhibitors to the surfaceof a-amylases Biologia 60(16):27-36.

2004

55.

 Eva Helena Johansson, Jan Neuhard, Martin Willemoes and Sine Larsen. (2004) Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetramic Cytidine Deaminase Biochemistry 43:6020-6029.

56.

 Eva Johansson, Jan Neuhard, Martin Willemoës and Sine Larsen. (2004) Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase Biochemistry 43(20):6020-9.

57.

 J. Nielsen, M. A. Kristensen, Martin Willemoes, F. C. Nielsen and Jan Christiansen. (2004) Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability Nucleic Acids Research 32(14):4368-4376.

58.

 Martin Willemoes. (2004) Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase Archives of Biochemistry and Biophysics 424:105-111.

2003

59.

 Martin Willemoes and Sine Larsen. (2003) Substrate inhibition of Lactococcus lactis cytidine 5'-triphosphate synthase by ammonium chloride is enhanced by salt-dependent tetramer dissociation Archives of Biochemistry and Biophysics 413:17-22.

60.

 Martin Willemoes. (2003) Thr-431 and Arg-433 Are Part of a Conserved Sequence Motif of the Glutamine Amidotransferase Domain of CTP Synthases and Are Involved in GTP Activation of the Lactococcus lactis Enzyme Journal of Biological Chemistry 278(11):9407-9411.

2002

61.

 Martin Willemoes and Bent Walther Sigurskjold. (2002) Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis FEBS Journal 269:4772-4779.

62.

 Martin Willemoës, Mogens Kilstrup, Peter Roepstorff and Karin Hammer. (2002) Proteome analysis of a Lactococcus lactis strain overexpressing gapA suggests that the gene product is an auxiliary glyceraldehyde 3-phosphate dehydrogenase Proteomics 2(8):1041-1046.

2001

63.

 Steen L.L. Wadskov-Hansen, Martin Willemoes, Jan Martinussen, Karin Hammer, Jan Neuhard and Sine Larsen. (2001) Cloning and Verification of the Lactococcus lactis pyrG Gene and Characterization of th Gene Product, CTP Synthase Journal of Biological Chemistry 276:38002-38009.

2000

64.

 Martin Willemoes, Bjarne Hove-Jensen and Sine Larsen. (2000) Steady State Kinetic Model for the Binding of Substrates and Allosteric Effectors to Escherichia coli Phosphoribosyl-diphosphate Synthase. Journal of Biological Chemistry 45:35408-35412.

1997

65.

 Martin Willemoës and Bjarne Hove-Jensen. (1997) Binding of Divalent Magnesium by Escherichia coli Phosphoribosyl Diphosphate Synthetase Biochemistry 36(16):5078-5083.

1996

66.

 Martin Willemoës, Dan Nilsson and Bjarne Hove-Jensen. (1996) Effects of mutagenesis of aspartic acid residues in the putative phosphoribosyl diphosphate binding site of Escherichia coli phosphoribosyl diphosphate synthetase on metal ion specificity and ribose-5-phosphate binding Biochemistry 35(25):8181-8186.

Last update: 17-11-2024 15:01:35. Next update: 17-11-2024 16:41:35