Error-free DNA repair – Lisby group

The research of my laboratory is focused on the spatio-temporal organization and regulation of homologous recombination (HR) and its role in maintaining genome integrity. We take a cell biological and genetic approach to study HR in human cells and the yeast  Saccharomyces cerevisiae. Particular areas of interest are regulation of chromatin structure during HR, post-translational modification of HR proteins and the molecular architecture of HR complexes in living cells. We are particularly interested in understanding molecular mechanisms relevant to cancer predisposition, neurological disorders and premature ageing syndromes, and in utilizing homologous recombination in CRISPR-Cas9 gene-editing.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Staff

Name Title Phone E-mail
Anne Katrine Wrist Simonsen PhD student +45 353-34924 E-mail
Ernest Lim PhD fellow +45 353-34107 E-mail
Hoa Phan Laboratory technician +45 353-31872 E-mail
Jacob Kwasi Autzen PhD fellow   E-mail
Keerthana Stine Viswalingam PhD fellow +45 353-33324 E-mail
Michael Lisby Professor +45 353-22120 E-mail
Steen Holmberg Associate professor, research and development +45 353-22119 E-mail

Contact


Principal investigator
Professor Michael Lisby
Section for Functional Genomics
Ole Maaloees Vej 5
DK-2200 Copenhagen N, Denmark
Email: mlisby@bio.ku.dk
Phone: +45 3532 2120