Publications from

Total publications from unit:

2025

1.

 Vilius Kurauskas, Sophia P Albrechtsen, Sarah Gersing, Kristoffer E Johansson, Rasmus Hartmann-Petersen, Martin Willemoës and Jakob R Winther. (2025) A Highly Stable Engineered Disulfide Bond in the Dimer Interface of E. coli Orotate Phosphoribosyl Transferase Measures Cytosolic Redox Conditions in Yeast. Biochemistry.

2.

 Sven Larsen-Ledet, Søren Lindemose, Aleksandra Panfilova, Sarah Gersing, Caroline H. Suhr, Aitana Victoria Genzor, Heleen Lanters, Sofie V. Nielsen, Kresten Lindorff-Larsen, Jakob R. Winther, Amelie Stein and Rasmus Hartmann-Petersen. (2025) Systematic characterization of indel variants using a yeast-based protein folding sensor Structure 33(2):262-273.e6.

2024

3.

 Fenne Marjolein Dijkema, Marta Iglesia Escarpizo-Lorenzana, Matilde Knapkøien Nordentoft, Hanna Christin Rabe, Cagla Sahin, Michael Landreh, Rui Mamede Branca, Esben Skipper Sørensen, Brian Christensen, Andreas Prestel, Kaare Teilum and Jakob Rahr Winther. (2024) A suicidal and extensively disordered luciferase with a bright luminescence Protein Science 33(8).

2023

4.

 Karen Skriver, Signe A. Sjørup, Annette E. Langkilde, Evanthia Balouka, Casper S. Christensen, Kathrine Carbel, Jens N. V. Decker, David N. Essenbæk, Justus F. Gräf, Camilla H. Jessen, Peter Kristensen, Christoffer Merrild, Tobias S. Mortensen, Isabella F. Nalepa, Bjørn W. Nordsteen, Sophie K. Svoren, Matthijs van Hall, Jan Weicher, Malene L. Wind, Danping Zhang, Daniel Saar, Helle Blæsild, Martin Stahlhut, Kim V. Andersen, Robert Dagil, Bente Vestergaard, Marie L. Ryberg and Birthe B. Kragelund. (2023) Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching The Biophysicist 4(2):1-7.

5.

 Kristoffer E Johansson, Kresten Lindorff-Larsen and Jakob R Winther. (2023) Global analysis of multi-mutants to improve protein function Journal of Molecular Biology 435(8).

2022

6.

 Amalie Carnbring Bonde, Jacob Lund, Jens Jacob Hansen, Jakob Rahr Winther, Per Franklin Nielsen, Stefan Zahn, Peter Tiainen, Ole Hvilsted Olsen, Helle Heibroch Petersen and Jais Rose Bjelke. (2022) The functional role of the autolysis loop in the regulation of factor X upon hemostatic response Journal of Thrombosis and Haemostasis 20(3):589-599.

7.

 Dennis K. Hansen, Anders Lønstrup Hansen, Johanna M. Koivisto, Bashar Shuoker, Maher Abou Hachem, Jakob R. Winther and Martin Willemoës. (2022) Engineering Bifidobacterium longum Endo-α-N-acetylgalactosaminidase for Neu5Acα2-3Ga1β1-3Ga1NAc reactivity on Fetuin Archives of Biochemistry and Biophysics 725.

8.

 Johanna Maarit Koivisto, Nina Rødtness Poulsen, Benedikte Stoklund Larsen, M. G. M. Weibull, Amelie Stein, Fabio Doro, Jakob Rahr Winther, Kresten Lindorff-Larsen and Martin Willemoës. (2022) Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system The Biochemical journal 479(4):479-501.

9.

 Rasmus Krogh Norrild, Kristoffer Enøe Johansson, Charlotte O'Shea, Jens Preben Morth, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2022) Increasing protein stability by inferring substitution effects from high-throughput experiments Cell Reports Methods 2(11).

2021

10.

 Amanda Bering Abildgaard, Jakob Rahr Winther, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2021) VM i molekylære puslespil Weekendavisen: Ideer(15):11.

11.

 Amanda Bering Abildgaard, Jakob Rahr Winther, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2021) VM i molekylære puslespil Weekendavisen: Ideer(15):11.

12.

 Amanda Bering Abildgaard, Jakob R. Winther, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2021) Molekylære stavefejl Weekendavisen, Ideer.

13.

 Altair Brito dos Santos, Line Koch Skaanning, Eyd Mikkelsen, Cesar Ramon Romero Leguizamon, Morten Pilgaard Kristensen, Anders Bue Klein, Siganya Siganya Thaneshwaran, Annette Eva Langkilde and Kristi Anne Kohlmeier. (2021) α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum and the Substantia Nigra Journal of Parkinson's Disease 11(4):1773-1790.

14.

 F. I. Marin, K. E. Johansson, C. Oâ??Shea, K. Lindorff-Larsen and J.R. Winther. (2021) Computational and experimental assessment of backbone templates for computational protein design Biochemistry.

15.

 Fenne Marjolein Dijkema, Matilde Knapkøien Nordentoft, Anders Krøll Didriksen, Anders Sværke Corneliussen, Martin Willemoës and Jakob R. Winther. (2021) Flash properties of Gaussia luciferase are the result of covalent inhibition after a limited number of cycles Protein Science 30(3):638-649.

16.

 Frederikke Isa Marin, Kristoffer Enøe Johansson, Charlotte O'Shea, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2021) Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold The Journal of Physical Chemistry B 125(40):11141-11149.

17.

 Mia L. Abramsson, Cagla Sahin, Jonathan T. S. Hopper, Rui M. M. Branca, Jens Danielsson, Mingming Xu, Shane A. Chandler, Nicklas Ã?sterlund, Leopold L. Ilag, Axel Leppert, Joana Costeira-Paulo, Lisa Lang, Kaare Teilum, Arthur Laganowsky, Justin L. P. Benesch, Mikael Oliveberg, Carol V. Robinson, Erik G. Marklund, Timothy M. Allison, Jakob R. Winther and Michael Landreh. (2021) Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry JACS Au 1(12):2385-2393.

18.

 Oana N. Antonescu, Andreas Rasmussen, Nicole A. M. Damm, Ditte F. Heidemann, Roman Popov, Alexander Nesterov-Mueller, Kristoffer E. Johansson and Jakob R. Winther. (2021) Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays PLoS ONE 16(2).

19.

 Stefan Hervø-Hansen, Casper Højgaard, Kristoffer Enøe Johansson, Yong Wang, Khadija Wahni, David Young, Joris Messens, Kaare Teilum, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2021) Charge Interactions in a Highly Charge-Depleted Protein Journal of the American Chemical Society 143(6):2500-2508.

2020

20.

 Caroline Kampmeyer, Jens V. Johansen, Christian Holmberg, Magnus Karlson, Sarah K. Gersing, Heloisa N. Bordallo, Birthe B. Kragelund, Mathilde Hauge Lerche, Isabelle Jourdain, Jakob R. Winther and Rasmus Hartmann-Petersen. (2020) Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water A C S Synthetic Biology 9(4):733-748.

2019

21.

 Benjamin Bjerre, Jakob Nissen, Mikkel Madsen, Jurate Kamarauskaite, Rasmus K Norrild, Peter C Holm, Mathilde K Nordentoft, Charlotte O'Shea, Martin Willemoës, Kristoffer E Johansson and Jakob R Winther. (2019) Improving folding properties of computationally designed proteins Protein Engineering Design and Selection (Print) 32(3):145-151.

22.

 Dennis K. Hansen, Jakob R. Winther and Martin Willemoës. (2019) Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-α-N-acetylgalactosaminidase Carbohydrate Research 480:54-60.

23.

 Niels Hadrup, Kristina Bram Knudsen, Trine Berthing, Henrik Wolff, Stefan Bengtson, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob Rahr Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Harri Alenius, Hannu Norppa, Håkan Wallin and Ulla Vogel. (2019) Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses Environmental Toxicology and Pharmacology 66:116-125.

2018

24.

 Marit Ilves, Sara Vilske, Kukka Aimonen, Hanna K. Lindberg, Saila Pesonen, Irene Wedin, Markus Nuopponen, Esa Vanhala, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel, Henrik Wolff, Hannu Norppa, Kai Savolainen and Harri Alenius. (2018) Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month Nanotoxicology 12(7):729-746.

25.

 Kristoffer Enøe Johansson and Jakob R. Winther. (2018) Protein evolution Nature Chemical Biology 14(3):202-204.

26.

 Birte Hoecker and Jakob R. Winther. (2018) Editorial overview: A perspective on protein evolution Current Opinion in Structural Biology 48:viii-ix.

27.

 Casper Højgaard, Henrik Vinther Sørensen, Jan Skov Pedersen, Jakob Rahr Winther and Daniel Erik Otzen. (2018) Can a Charged Surfactant Unfold an Uncharged Protein? Biophysical Journal 115(11):2081-2086.

28.

 Paul Santner, Joao Miguel da Silva Martins, Caroline Kampmeyer, Rasmus Hartmann-Petersen, Jonas S. Laursen, Amelie Stein, Christian A Olsen, Isaiah T Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants Biochemistry 57(41):5957-5968.

2017

29.

 Sirke Virkkunen, Henrik Wolff, Caj Haglund, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel and Jaana Hagström. (2017) Positive staining for cellulose in oral pulse granuloma Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 123(4):464-467.

30.

 Tina Mostrup Kousted, Otto Kalliokoski, Sofie Kjellerup Christensen, Jakob R. Winther and Jann Hau. (2017) Exploring the antigenic response to multiplexed immunizations in a chicken model of antibody production Heliyon 3(3).

31.

 Amanda Bering Abildgaard, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen and Jakob R. Winther. (2017) Evolution i overhalingsbanen Weekendavisen 2017(50):Ideer: 13.

2016

32.

 Casper Højgaard, Christian Kofoed, Roall Espersen, Kristoffer Enøe Johansson, Mara Villa, Martin Willemoës, Kresten Lindorff-Larsen, Kaare Teilum and Jakob R. Winther. (2016) A soluble, folded protein without charged amino acid residues Biochemistry 55(28):3949â??3956.

33.

 Kristoffer Enøe Johansson, Nicolai Tidemand Johansen, Signe Christensen, Scott Horowitz, James C. A. Bardwell, Johan Gotthardt Olsen, Martin Willemoës, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck and Jakob R. Winther. (2016) Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template Journal of Molecular Biology 428(21):4361-4377.

2015

34.

 Kristina Bram Knudsen, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Sara Vilske, Kukka Aimonen, Ingrid Elise Konow Weydahl, Harri Alenius, Hannu Norppa, Henrik Wolff, Erik Håkan Richard Wallin and Ulla Vogel. (2015) Visualization of nanofibrillar cellulose in biological tissues using a biotinylated carbohydrate binding module of β-1,4-Glycanase Chemical Research in Toxicology 28(8):1627-1635.

2014

35.

 Caspar Elo Christensen, Magnus Karlsson, Jakob R. Winther, Pernille Rose Jensen and Mathilde H. Lerche. (2014) Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes The Journal of Biological Chemistry 289(4):2344-2352.

36.

 Jakob R. Winther and Colin Thorpe. (2014) Quantification of thiols and disulfides BBA General Subjects 1840(2):838-846.

37.

 Jan Halborg Jensen, Martin Willemoës, Jakob R. Winther and Luca De Vico. (2014) In Silico prediction of mutant HIV-1 proteases cleaving a target sequence P L o S One 9(5).

38.

 Kristine Steen Jensen, Jeppe Trudslev Pedersen, Jakob R. Winther and Kaare Teilum. (2014) The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin Biochemistry 53(15):2533-2540.

39.

 Lars Behrendt, Jeppe Lund Nielsen, Søren Johannes Sørensen, Anthony W. D. Larkum, Jakob R. Winther and Michael Kühl. (2014) Rapid TaqMan-based quantification of chlorophyll d-containing cyanobacteria in the genus Acaryochloris Applied and Environmental Microbiology 80(10):3244-3249.

40.

 Michael Riis Hansen, Eric W. Barr, Kaj Frank Jensen, Martin Willemoës, Charles Grubmeyer and Jakob R. Winther. (2014) Catalytic site interactions in yeast OMP synthase Archives of Biochemistry and Biophysics 542:28-38.

2013

41.

 Davide Montero, Christine Tachibana, Jakob R. Winther and Christian Appenzeller-Herzog. (2013) Intracellular glutathione pools are heterogeneously concentrated Redox Biology 1(1):508-513.

42.

 Jakob R. Winther, Helen Webb and John Kay. (2013) Saccharopepsin Handbook of Proteolytic Enzymes 1:128-133.

43.

 Rosa Rebecca Erritzøe Hansen, Mieko Otsu, Ineke Braakman and Jakob R. Winther. (2013) Quantifying changes in the cellular thiol-disulfide status during differentiation of B cells into antibody-secreting plasma cells International Journal of Cell Biology 2013.

2012

44.

 Jonas Willum Nielsen, Karina Krarup Sand, Christian Schack Pedersen, L. Z. Lakshtanov, Jakob R. Winther, Martin Willemoës and Susan Louise Svane Stipp. (2012) Polysaccharide effects on calcite growth Crystal Growth & Design 12(10):4906-4910.

45.

 Jonas Willum Nielsen, Kristine Steen Jensen, Rosa Rebecca Erritzøe Hansen, Charlotte Held Gotfredsen and Jakob R. Winther. (2012) A fluorescent probe which allows highly specific thiol labeling at low pH Analytical Biochemistry 421(1):115-120.

46.

 Jonas Willum Nielsen, Nina Rødtness Poulsen, Anna Margit Susanne Johnsson, Jakob R. Winther, Susan Louise Svane Stipp and Martin Willemoës. (2012) Metal-ion dependent catalytic properties of Sulfolobus solfataricus class II α-mannosidase Biochemistry 51(40):8039-8046.

47.

 Lea Cecilie Christensen, Njal Winther Jensen, Andrea Lages Lino Vala, Jurate Kamarauskaite, Linda Christina Johansson, Jakob R. Winther, Kay Hofmann, Kaare Teilum and Lars Ellgaard. (2012) The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region Journal of Biological Chemistry 287(31):26388-26399.

2011

48.

 Kristine Steen Jensen, Jakob R Winther and Kaare Teilum. (2011) Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states Journal of the American Chemical Society 133(9):3034-42.

49.

 Rasmus W. Nielsen, Christine Tachibana, Niels Erik Hansen and Jakob R Winther. (2011) Trisulfides in Proteins Antioxidants & Redox Signaling 15(1):67-75.

2010

50.

 Kenji Maeda, Per Hägglund, Olof Björnberg, Jakob R Winther and Birte Svensson. (2010) Kinetic and thermodynamic properties of two barley thioredoxin h isozymes, HvTrxh1 and HvTrxh2 FEBS Letters 584(15):3376-3380.

51.

 Rasmus Iversen, Peter Anders Andersen, Kristine Steen Jensen, Jakob R. Winther and Bent Walther Sigurskjold. (2010) Thiol-Disulfide Exchange between Glutaredoxin and Glutathione Biochemistry 49(4):810-820.

2009

52.

 Rosa E Hansen and Jakob R Winther. (2009) An introduction to methods for analyzing thiols and disulfides: Reactions, reagents, and practical considerations Analytical Biochemistry 394(2):147-58.

2008

53.

 Giuseppe Maulucci, Valentina Labate, Marina Mele, Emiliano Panieri, Giuseppe Arcovito, Tommaso Galeotti, Henrik Ã?stergaard, Jakob R Winther, Marco De Spirito and Giovambattista Pani. (2008) High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein Science Signaling 1(43):pl3 1-15.

54.

 H Reynaldo López-Mirabal, Jakob R Winther, Michael Thorsen and Morten C Kielland-Brandt. (2008) Mutations in the RAM network confer resistance to the thiol oxidant 4,4'-dipyridyl disulfide Molecular Genetics and Genomics 279(6):629-42.

2007

55.

 H Reynaldo López-Mirabal and Jakob R Winther. (2007) The thiol oxidant dipyridyl disulfide can supply the PDI-Ero1p pathway with additional oxidative equivalents. Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology 92(4):463-72.

56.

 H Reynaldo López-Mirabal and Jakob R Winther. (2007) Redox characteristics of the eukaryotic cytosol. BBA General Subjects.

57.

 H Reynaldo López-Mirabal, Jakob R Winther and Morten C Kielland-Brandt. (2007) Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae. Bioscience, Biotechnology, and Biochemistry 71(12):2934-42.

58.

 H Reynaldo López-Mirabal, Michael Thorsen, Morten C Kielland-Brandt, Michel B Toledano and Jakob R Winther. (2007) Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide. FEMS Yeast Research 7(3):391-403.

59.

 Kjell O Håkansson and Jakob R Winther. (2007) Structure of glutaredoxin Grx1p C30S mutant from yeast. Acta Crystallographica. Section D: Biological Crystallography 63:288-94.

60.

 Rosa E Hansen, Henrik Ã?stergaard, Per Nørgaard and Jakob R Winther. (2007) Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4'-dithiodipyridine. Analytical Biochemistry 363(1):77-82.

61.

 Wenzhong Wang, Jakob R Winther and Colin Thorpe. (2007) Erv2p: characterization of the redox behavior of a yeast sulfhydryl oxidase. Biochemistry 46(11):3246-54.

2006

62.

 Kjell Ove Håkansson, Henrik Ã?stergaard and Jakob R. Winther. (2006) Crystallization of mutant forms of glutaredoxin Grx1p from yeast Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 62(9):920-922.

63.

 Marianne Paulsen, Connie Lund, Zarqa Akram, Jakob R Winther, Nina Horn and Lisbeth Birk Møller. (2006) Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites American Journal of Human Genetics 79(2):214-29.

64.

 Olof Björnberg, Henrik Ã?stergaard and Jakob R Winther. (2006) Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein Biochemistry 45(7):2362-71.

65.

 Olof Björnberg, Henrik Ostergaard and Jakob R Winther. (2006) Measuring intracellular redox conditions using GFP-based sensors Antioxidants & Redox Signaling 8:354-61.

2004

66.

 Camilla Christiansen, Phaedria M. St. Hilaire and Jakob R. Winther. (2004) Fluorometric polyethyleneglycol-peptide hybrid substrates for quantitative assay of protein disulfide isomerase Analytical Biochemistry 333(1):148-155.

67.

 Henrik Ã?stergaard, Christine Tachibana and Jakob R. Winther. (2004) Monitoring disulfide bond formation in the eukaryotic cytosol Journal of Cell Biology 166(3):337-345.

68.

 Ruoyu Xiao, Bonney Wilkinson, Anton Solovyov, Jakob R. Winther, Arne Holmgren, Johanna Lundström-Ljung and Hiram F. Gilbert. (2004) The Contributions of Protein Disulfide Isomerase and Its Homologues to Oxidative Protein Folding in the Yeast Endoplasmic Reticulum Journal of Biological Chemistry 279(48):49780-49786.

2003

69.

 Martin Willemoes. (2003) Thr-431 and Arg-433 Are Part of a Conserved Sequence Motif of the Glutamine Amidotransferase Domain of CTP Synthases and Are Involved in GTP Activation of the Lactococcus lactis Enzyme Journal of Biological Chemistry 278(11):9407-9411.

70.

 Per Nørgaard, Christine Tachibana, Anette W Bruun and Jakob R. Winther. (2003) Gene regulation in response to protein disulphide isomerase deficiency Yeast 20(7):645-652.

2002

71.

 Martin Willemoes and Bent Walther Sigurskjold. (2002) Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis FEBS Journal 269:4772-4779.

2001

72.

 Henrik Ã?stergaard, Anette Henriksen, Flemming G. Hansen and Jakob R. Winther. (2001) Shedding light on disulfide bond formation EMBO Journal 20(21):5853-5862.

73.

 K. Møller, L. D. Tidemand, J. R. Winther, L. Olsson, J. Piskur and J. Nielsen. (2001) Production of a heterologous proteinase A by Saccharomyces kluyveri Applied Microbiology and Biotechnology 57:216-219.

74.

 Kresten Lindorff-Larsen and Jakob R. Winther. (2001) Surprisingly high stability of barley lipid transfer protein, LTP1, towards denaturant, heat and proteases FEBS Letters 488(3):145-148.

75.

 Kresten Lindorff-Larsen, Mathilde H. Lerche, Flemming Martin Poulsen, Peter Roepstorff and Jakob R. Winther. (2001) Barley lipid transfer protein, LTP1, contains a new type of lipid-like post-translational modification Journal of Biological Chemistry 276(36):33547-33553.

76.

 Lowri H. Phylip, Wendy E. Lees, Brian G. Brownsey, Daniel Bur, Ben M. Dunn, Jakob R. Winther, Alla Gustchina, Mi Li, Terry Copeland, Alexander Wlodawer and John Kay. (2001) The Potency and Specificity of the Interaction between the IA3 Inhibitor and Its Target Aspartic Proteinase from Saccharomyces cerevisiae Journal of Biological Chemistry 276(3):2023-2030.

77.

 Per Nørgaard, Vibeke Westphal, Christine Tachibana, Lene Alsøe, Bjørn Holst and Jakob R. Winther. (2001) Functional differences in yeast protein disulfide isomerases Journal of Cell Biology 152(3):553-562.

2000

78.

 M.O. Badasso, J.A. Read, V. Dhanaraj, J.B. Cooper, S.P. Wood, T.L. Blundell, T. Dreyer and J. Winther. (2000) Purification, co-crystallization and preliminary X-ray analysis of the natural aspartic proteinase inhibitor I(A)3 complexed with saccharopepsin from Saccharomyces cerevisiae Acta Crystallographica Section D: Biological Crystallography.

79.

 Mi Li, Lowri H. Phylip, Wendy E. Lees, Jakob R. Winther, Ben M. Dunn, Alexander Wlodawer, John Kay and Alla Gustchina. (2000) The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix Nature Structural & Molecular Biology 7(2):113-117.

1998

80.

 Anette W. Bruun, Ib Svendsen, Susanne O. Sørensen, Morten C. Kielland-Brandt and Jakob R. Winther. (1998) A High-Affinity Inhibitor of Yeast Carboxypeptidase Y Is Encoded by TFS1 and Shows Homology to a Family of Lipid Binding Proteins Biochemistry 37(10):3351-3357.

81.

 V Westphal, J C Spetzler, M Meldal, U Christensen and Jakob R. Winther. (1998) Kinetic analysis of the mechanism and specificity of protein-disulfide isomerase using fluorescence-quenched peptides Journal of Biological Chemistry 273(39):24992-9.

1997

82.

 Bjørn Holst, Christine Tachibana and Jakob R. Winther. (1997) Active site mutations in yeast protein disulfide isomerase cause dithiothreitol sensitivity and a reduced rate of protein folding in the endoplasmic reticulum Journal of Cell Biology 138(6):1229-1238.

83.

 H Van Den Hazel, A M Wolff, Morten Kielland-Brandt and Jakob R. Winther. (1997) Mechanism and ion-dependence of in vitro autoactivation of yeast proteinase A Biochemical Journal:339-44.

1996

84.

 B Holst, A W Bruun, Morten Kielland-Brandt and Jakob R. Winther. (1996) Competition between folding and glycosylation in the endoplasmic reticulum E M B O Journal 15(14):3538-46.

85.

 F van Voorst, Morten Kielland-Brandt and Jakob R. Winther. (1996) Mutational analysis of the vacuolar sorting signal of procarboxypeptidase Y in yeast shows a low requirement for sequence conservation Journal of Biological Chemistry 271(2):841-6.

86.

 H B Van Den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1996) Review Yeast (Chichester, England) 12(1):1-16.

87.

 V Westphal, E G Marcusson, Jakob R. Winther, S D Emr and H B van den Hazel. (1996) Multiple pathways for vacuolar sorting of yeast proteinase A Journal of Biological Chemistry 271(20):11865-70.

1995

88.

 H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1995) Random substitution of large parts of the propeptide of yeast proteinase A Journal of Biological Chemistry 270(15):8602-9.

1994

89.

 C Ramos, Jakob R. Winther and Morten Kielland-Brandt. (1994) Requirement of the propeptide for in vivo formation of active yeast carboxypeptidase Y Journal of Biological Chemistry 269(9):7006-12.

90.

 S O Sørensen and Jakob R. Winther. (1994) Active-site residues of procarboxypeptidase Y are accessible to chemical modification BBA General Subjects 1205(2):289-93.

91.

 S O Sørensen, H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1994) pH-dependent processing of yeast procarboxypeptidase Y by proteinase A in vivo and in vitro European Journal of Biochemistry 220(1):19-27.

1993

92.

 P Sørensen, Jakob R. Winther, N C Kaarsholm and F M Poulsen. (1993) The pro region required for folding of carboxypeptidase Y is a partially folded domain with little regular structural core Biochemistry 32(45):12160-6.

1992

93.

 H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1992) Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens European Journal of Biochemistry 207(1):277-83.

1991

94.

 Jakob R. Winther, T H Stevens and Morten Kielland-Brandt. (1991) Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity European Journal of Biochemistry 197(3):681-9.

1987

95.

 JR WINTHER, K BREDDAM and Jakob R. Winther. (1987) THE FREE SULFHYDRYL-GROUP (CYS341) OF CARBOXYPEPTIDASE-Y - FUNCTIONAL-EFFECTS OF MUTATIONAL SUBSTITUTIONS Carlsberg Research Communications 52(4):263-273.

1985

96.

 Jakob R. Winther, Morten C. Kielland-Brandt and Klaus Breddam. (1985) Increased hydrophobicity of the Sâ?²1 binding site in carboxypeptidase Y obtained by site-directed mutagenesis Carlsberg Research Communications 50(5):273-284.

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