Publications from

Total publications from unit:

2024

1.

Alex S. Holehouse and Birthe B. Kragelund. (2024) The molecular basis for cellular function of intrinsically disordered protein regions Nature Reviews Molecular Cell Biology 25:187–211.

2.

Daniele Montepietra, Giulio Tesei, João M. Martins, Micha B.A. Kunze, Robert B. Best and Kresten Lindorff-Larsen. (2024) FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries Communications Biology 7(1).

3.

Dilraj Lama, Thibault Vosselman, Cagla Sahin, Judit Liaño-pons, Carmine P. Cerrato, Lennart Nilsson, Kaare Teilum, David P. Lane, Michael Landreh and Marie Arsenian Henriksson. (2024) A druggable conformational switch in the c-MYC transactivation domain Nature Communications 15(1).

4.

Frederik Friis Theisen, Andreas Prestel, Steffie Elkjær, Yannick H.A. Leurs, Nicholas Morffy, Lucia C. Strader, Charlotte O’Shea, Kaare Teilum, Birthe B. Kragelund and Karen Skriver. (2024) Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants Nature Communications 15(1).

5.

Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E. Knudsen, Francesco Pesce, Kristoffer E. Johansson and Kresten Lindorff-Larsen. (2024) Conformational ensembles of the human intrinsically disordered proteome Nature 626:897-904.

6.

Jacob Ardenkjær-Skinnerup, Daniel Saar, Patricia S.S. Petersen, Mikael Pedersen, Terje Svingen, Birthe B. Kragelund, Niels Hadrup, Gitte Ravn-Haren, Brice Emanuelli, Kristy A. Brown and Ulla Vogel. (2024) PPAR? antagonists induce aromatase transcription in adipose tissue cultures Biochemical Pharmacology 222.

7.

Johan G Olsen, Andreas Prestel, Noah Kassem, Sebastian S Broendum, Hossain Mohammad Shamim, Signe Simonsen, Martin Grysbæk, Josefine Mortensen, Louise Lund Rytkjær, Gitte W Haxholm, Riccardo Marabini, Christian Holmberg, Antony M Carr, Ramon Crehuet, Olaf Nielsen and Birthe B Kragelund. (2024) Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs Nucleic acids symposium series 52(4):2030–2044.

8.

Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer E. Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L. Powell, Magnus K.N. Have, Vibe H. Oestergaard, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2024) A mutational atlas for Parkin proteostasis Nature Communications 15(1).

9.

Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2024) Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants Nature Communications 15(1).

10.

Nicolas Daffern, Kristoffer E. Johansson, Zachary T. Baumer, Nicholas R. Robertson, Janty Woojuh, Matthew A. Bedewitz, Zoë Davis, Ian Wheeldon, Sean R. Cutler, Kresten Lindorff-Larsen and Timothy A. Whitehead. (2024) GMMA Can Stabilize Proteins Across Different Functional Constraints Journal of Molecular Biology 436(11).

11.

Philip Weidner, Daniel Saar, Michaela Söhn, Torsten Schroeder, Yanxiong Yu, Frank G. Zöllner, Norbert Ponelies, Xiaobo Zhou, André Zwicky, Florian N. Rohrbacher, Vijaya R. Pattabiraman, Matthias Tanriver, Alexander Bauer, Hazem Ahmed, Simon M. Ametamey, Philipp Riffel, Rony Seger, Jeffrey W. Bode, Rebecca C. Wade, Matthias P.A. Ebert, Birthe B. Kragelund and Elke Burgermeister. (2024) Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction Cancer Letters 588.

12.

Sarah Gersing, Thea K. Schulze, Matteo Cagiada, Amelie Stein, Frederick P. Roth, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2024) Characterizing glucokinase variant mechanisms using a multiplexed abundance assay Genome Biology 25(1).

13.

Sveinn Bjarnason, Jordan A.P. McIvor, Andreas Prestel, Kinga S. Demény, Jakob T. Bullerjahn, Birthe B. Kragelund, Davide Mercadante and Pétur O. Heidarsson. (2024) DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2 Nature Communications 15(1).

2023

14.

Felix Kümmerer, Simone Orioli and Kresten Lindorff-larsen. (2023) Fitting Force Field Parameters to NMR Relaxation Data Journal of Chemical Theory and Computation 19(12):3741-3751.

15.

Abigail Barclay, Birthe B. Kragelund, Lise Arleth and Martin Cramer Pedersen. (2023) Modeling of flexible membrane-bound biomolecular complexes for solution small-angle scattering Journal of Colloid and Interface Science 635:611-621.

16.

Amanda B. Abildgaard, Sofie Nielsen, Inge Bernstein, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2023) Lynch syndrome, molecular mechanisms and variant classification British Journal of Cancer 128.

17.

Amanda B. Abildgaard, Vasileios Voutsinos, Søren D. Petersen, Fia B. Larsen, Caroline Kampmeyer, Kristoffer E. Johansson, Amelie Stein, Tommer Ravid, Claes Andréasson, Michael K. Jensen, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2023) HSP70-binding motifs function as protein quality control degrons Cellular and Molecular Life Sciences 80(1).

18.

Andreas Oxenfarth, Felix Kümmerer, Sandro Bottaro, Robbin Schnieders, György Pinter, Hendrik R.A. Jonker, Boris Fürtig, Christian Richter, Martin Blackledge, Kresten Lindorff-Larsen and Harald Schwalbe. (2023) Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop Journal of the American Chemical Society 145(30):16557-16572.

19.

Antoni Kowalski, Cristine Betzer, Sigrid Thirup Larsen, Emil Gregersen, Estella A. Newcombe, Montaña Caballero Bermejo, Viktor Wisniewski Bendtsen, Jorin Diemer, Christina V. Ernstsen, Shweta Jain, Alicia Espiña Bou, Annette Eva Langkilde, Lene N. Nejsum, Edda Klipp, Robert Edwards, Birthe B. Kragelund, Poul Henning Jensen and Poul Nissen. (2023) Monomeric a-synuclein activates the plasma membrane calcium pump EMBO Journal 42(23).

20.

Audrone Valanciute, Lasse Nygaard, Henrike Zschach, Michael Maglegaard Jepsen, Kresten Lindorff-Larsen and Amelie Stein. (2023) Accurate protein stability predictions from homology models Computational and Structural Biotechnology Journal 21:66-73.

21.

Birthe B Kragelund, Claus Juul Loland, Guillermo Montoya, Nikos Hatzakis, Karen L Martinez, Michael Gajhede, Caspar Elo Christensen and Lucy Holt. (2023) Realizing integration in structural biology: The 2022 ISBUC Annual Meeting Structure 31(7):747-754.

22.

Cagla Sahin, Aikaterini Motso, Xinyu Gu, Hannes Feyrer, Dilraj Lama, Tina Arndt, Anna Rising, Genis Valentin Gese, B. Martin Haellberg, Erik. G. Marklund, Nicholas P. Schafer, Katja Petzold, Kaare Teilum, Peter G. Wolynes and Michael Landreh. (2023) Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures Journal of the American Chemical Society 145(19).

23.

Daniel Flores-Téllez, Mathias Due Tankmar, Sören von Bülow, Junyu Chen, Kresten Lindorff-Larsen, Peter Brodersen and Laura Arribas-Hernández. (2023) Insights into the conservation and diversification of the molecular functions of YTHDF proteins PLOS Genetics 19(10).

24.

F. Emil Thomasen, Matthew J. Cuneo, Tanja Mittag and Kresten Lindorff-Larsen. (2023) Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations eLife 12.

25.

Fia B. Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2023) Rare Catechol-O-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets Biochemistry 62(8).

26.

Francesco Pesce and Kresten Lindorff-Larsen. (2023) Combining Experiments and Simulations to Examine the Temperature-Dependent Behavior of a Disordered Protein Journal of Physical Chemistry B 127(28):6277-6286.

27.

Francesco Pesce, Estella A. Newcombe, Pernille Seiffert, Emil E. Tranchant, Johan G. Olsen, Christy R. Grace, Birthe B. Kragelund and Kresten Lindorff-Larsen. (2023) Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins Biophysical Journal 122(2):310-321.

28.

Giulio Tesei and Kresten Lindorff-Larsen. (2023) Improved predictions of phase behaviour of intrinsically disordered proteins by tuning the interaction range Open Research Europe 2(94).

29.

Ida M. Vedel, Andreas Prestel, Zhenwei Zhang, Natalia T. Skawinska, Holger Stark, Pernille Harris, Birthe B. Kragelund and Günther H.J. Peters. (2023) Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand Structure (London, England : 1993) 31(6):689-699e6.

30.

Javier González-Delgado, Amin Sagar, Christophe Zanon, Kresten Lindorff-Larsen, Pau Bernadó, Pierre Neuvial and Juan Cortés. (2023) WASCO: A Wasserstein-based Statistical Tool to Compare Conformational Ensembles of Intrinsically Disordered Proteins Journal of Molecular Biology 435(14).

31.

Johanna Katarina Sofie Tiemann, Henrike Zschach, Kresten Lindorff-Larsen and Amelie Stein. (2023) Interpreting the molecular mechanisms of disease variants in human transmembrane proteins Biophysical Journal 122(11).

32.

Julie Maja Leth, Estella Anne Newcombe, Anne Louise Grønnemose, Jesper Tranekjær Jørgensen, Katrine Qvist, Anne Skovsbo Clausen, Line Bruhn Schneider Knudsen, Andreas Kjaer, Birthe Brandt Kragelund, Thomas Jørgen Dyreborg Jørgensen and Michael Ploug. (2023) Targeted imaging of uPAR expression in vivo with cyclic AE105 variants Scientific Reports 13.

33.

Kaare Teilum, Johan G. Olsen and Birthe B. Kragelund. (2023) Comment on “Intrinsic protein disorder uncouples affinity from binding specificity” Protein Science 32(4).

34.

Karen Skriver, Frederik Friis Theisen and Birthe B. Kragelund. (2023) Conformational entropy in molecular recognition of intrinsically disordered proteins Current Opinion in Structural Biology 83.

35.

Karen Skriver, Signe A. Sjørup, Annette E. Langkilde, Evanthia Balouka, Casper S. Christensen, Kathrine Carbel, Jens N. V. Decker, David N. Essenbæk, Justus F. Gräf, Camilla H. Jessen, Peter Kristensen, Christoffer Merrild, Tobias S. Mortensen, Isabella F. Nalepa, Bjørn W. Nordsteen, Sophie K. Svoren, Matthijs van Hall, Jan Weicher, Malene L. Wind, Danping Zhang, Daniel Saar, Helle Blæsild, Martin Stahlhut, Kim V. Andersen, Robert Dagil, Bente Vestergaard, Marie L. Ryberg and Birthe B. Kragelund. (2023) Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching The Biophysicist 4(2):1-7.

36.

Kristoffer E Johansson, Kresten Lindorff-Larsen and Jakob R Winther. (2023) Global analysis of multi-mutants to improve protein function Journal of Molecular Biology 435(8).

37.

Kristoffer E. Johansson, Bayan Mashahreh, Rasmus Hartmann-Petersen, Tommer Ravid and Kresten Lindorff-Larsen. (2023) Prediction of Quality-control Degradation Signals in Yeast Proteins Journal of Molecular Biology 435(2).

38.

Lasse M. Blaabjerg, Maher M. Kassem, Lydia L. Good, Nicolas Jonsson, Matteo Cagiada, Kristoffer E. Johansson, Wouter Boomsma, Amelie Stein and Kresten Lindorff-Larsen. (2023) Rapid protein stability prediction using deep learning representations eLife 12.

39.

Matteo Cagiada, Sandro Bottaro, Søren Lindemose, Signe M. Schenstrøm, Amelie Stein, Rasmus Hartmann-Petersen and Kresten Lindorff-Larsen. (2023) Discovering functionally important sites in proteins Nature Communications 14(1).

40.

Mikkel Madsen, Andreas Prestel, Eva Madland, Peter Westh, Anne Tondervik, Havard Sletta, Gunther H. J. Peters, Finn L. L. Aachmann, Birthe B. B. Kragelund and Birte Svensson. (2023) Molecular insights into alginate beta-lactoglobulin A multivalencies: The foundation for their amorphous aggregates and coacervation Protein Science 32(2).

41.

Mireya Martínez-Pérez, Frederic Aparicio, Laura Arribas-Hernández, Mathias Due Tankmar, Sarah Rennie, Sören von Bülow, Kresten Lindorff-Larsen, Peter Brodersen and Vicente Pallas. (2023) Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus EMBO Journal 42(18).

42.

Nina L. Jacobsen, Magnus Bloch, Peter S. Millard, Sarah F. Ruidiaz, Jonas D. Elsborg, Wouter Boomsma, Ruth Hendus-Altenburger, Rasmus Hartmann-Petersen and Birthe B. Kragelund. (2023) Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin-ligase Dma1 in vitro Protein Science 32(9).

43.

Raul Araya-Secchi, Katrine Bugge, Pernille Seiffert, Amalie Petry, Gitte W. Haxholm, Kresten Lindorff-Larsen, Stine Falsig Pedersen, Lise Arleth and Birthe B. Kragelund. (2023) The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate eLife 12.

44.

Sarah Gersing, Matteo Cagiada, Marinella Gebbia, Anette P. Gjesing, Atina G. Coté, Gireesh Seesankar, Roujia Li, Daniel Tabet, Jochen Weile, Amelie Stein, Anna L. Gloyn, Torben Hansen, Frederick P. Roth, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2023) A comprehensive map of human glucokinase variant activity Genome Biology 24(1).

45.

Steffie Elkjær, Amanda D. Due, Lise F. Christensen, Frederik F. Theisen, Lasse Staby, Birthe B. Kragelund and Karen Skriver. (2023) Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime Communications Biology 6.

46.

Thibaud Dieudonné, Felix Kümmerer, Michelle Juknaviciute Laursen, Charlott Stock, Rasmus Kock Flygaard, Syma Khalid, Guillaume Lenoir, Joseph A. Lyons, Kresten Lindorff-Larsen and Poul Nissen. (2023) Activation and substrate specificity of the human P4-ATPase ATP8B1 Nature Communications 14(1).

47.

Yash Chhabra, Pernille Seiffert, Rachel S. Gormal, Manon Vullings, Christine Mei Mei Lee, Tristan P. Wallis, Farhad Dehkhoda, Sowmya Indrakumar, Nina L. Jacobsen, Kresten Lindorff-Larsen, Nela Durisic, Michael J. Waters, Frédéric A. Meunier, Birthe B. Kragelund and Andrew J. Brooks. (2023) Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation Cell Reports 42(5).

48.

Yixin Rong, Sheila Ingemann Jensen, Kresten Lindorff-Larsen and Alex Toftgaard Nielsen. (2023) Folding of heterologous proteins in bacterial cell factories: Cellular mechanisms and engineering strategies Biotechnology Advances 63.

49.

Yulian Gavrilov, Andreas Prestel, Kresten Lindorff-Larsen and Kaare Teilum. (2023) Slow conformational changes in the rigid and highly stable chymotrypsin inhibitor 2 Protein Science 32(4).

50.

Zarah Forsberg, Anton A. Stepnov, Giulio Tesei, Yong Wang, Edith Buchinger, Sandra K. Kristiansen, Finn L. Aachmann, Lise Arleth, Vincent G.H. Eijsink, Kresten Lindorff-Larsen and Gaston Courtade. (2023) The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase Journal of Biological Chemistry 299(11).

2022

51.

Albert Escobedo, Jonathan Piccirillo, Juan Aranda, Tammo Diercks, Borja Mateos, Carla Garcia-Cabau, Macarena Sanchez-Navarro, Busra Topal, Mateusz Biesaga, Lasse Staby, Birthe B. Kragelund, Jesus Garcia, Oscar Millet, Modesto Orozco, Murray Coles, Ramon Crehuet and Xavier Salvatella. (2022) A glutamine-based single a-helix scaffold to target globular proteins Nature Communications 13.

52.

Anette P. Gjesing, Line Engelbrechtsen, Anne Cathrine B. Thuesen, Christian T. Have, Mette Hollensted, Niels Grarup, Allan Linneberg, Jens Steen Nielsen, Lotte B. Christensen, Reimar W. Thomsen, Kristoffer E. Johansson, Matteo Cagiada, Sarah Gersing, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Allan Vaag, Henrik T. Sørensen, Ivan Brandslund, Henning Beck-Nielsen, Oluf Pedersen, Jørgen Rungby and Torben Hansen. (2022) 14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes Diabetes Research and Clinical Practice 194.

53.

Bayan Mashahreh, Shir Armony, Kristoffer Enøe Johansson, Alon Chappleboim, Nir Friedman, Richard G. Gardner, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen and Tommer Ravid. (2022) Conserved degronome features governing quality control associated proteolysis Nature Communications 13(1).

54.

Caroline Kampmeyer, Sven Larsen-Ledet, Morten Rose Wagnkilde, Mathias Michelsen, Henriette K. M. Iversen, Sofie V. Nielsen, Søren Lindemose, Alberto Caregnato, Tommer Ravid, Amelie Stein, Kaare Teilum, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2022) Disease-linked mutations cause exposure of a protein quality control degron Structure 30(9):1245-1253.e5.

55.

Caroline Neumann, Lena Lindtoft Rosenbæk, Rasmus Kock Flygaard, Michael Habeck, Jesper Lykkegaard Karlsen, Yong Wang, Kresten Lindorff-Larsen, Hans Henrik Gad, Rune Hartmann, Joseph Anthony Lyons, Robert A. Fenton and Poul Nissen. (2022) Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity EMBO Journal 41(23).

56.

Esben B. Svenningsen, Rasmus N. Ottosen, Katrine H. Jørgensen, Marija Nisavic, Camilla K. Larsen, Bente K. Hansen, Yong Wang, Kresten Lindorff-Larsen, Thomas Tørring, Stephan M. Hacker, Johan Palmfeldt and Thomas B. Poulsen. (2022) The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21 RSC Chemical Biology 3(10):1216-1229.

57.

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver and Birthe B. Kragelund. (2022) How phosphorylation impacts intrinsically disordered proteins and their function Essays in Biochemistry 66(7):901-913.

58.

F. Emil Thomasen and Kresten Lindorff-Larsen. (2022) Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins Biochemical Society Transactions 50(1):541-554.

59.

F. Emil Thomasen, Francesco Pesce, Mette Ahrensback Roesgaard, Giulio Tesei and Kresten Lindorff-Larsen. (2022) Improving Martini 3 for Disordered and Multidomain Proteins Journal of Chemical Theory and Computation 18(4):2033-2041.

60.

Frederik Friis Theisen, Edoardo Salladini, Rikke Davidsen, Christina Jo Rasmussen, Lasse Staby, Birthe B. Kragelund and Karen Skriver. (2022) aa-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes Journal of Biological Chemistry 298(6).

61.

Heike I. Rösner, Martina Caldarini, Gregory Potel, Daniel Malmodin, Maria A. Vanoni, Alessandro Aliverti, Ricardo A. Broglia, Birthe B. Kragelund and Guido Tiana. (2022) The denatured state of HIV-1 protease under native conditions Proteins: Structure, Function, and Bioinformatics 90(1):96-109.

62.

Jacob H. Martinsen, Daniel Saar, Catarina B. Fernandes, Benjamin Schuler, Katrine Bugge and Birthe B. Kragelund. (2022) Structure, dynamics, and stability of the globular domain of human linker histone H1.0 and the role of positive charges Protein Science 31(4):918-932.

63.

Jesper E. Dreier, Andreas Prestel, João M. Martins, Sebastian S. Brøndum, Olaf Nielsen, Anna E. Garbers, Hiroaki Suga, Wouter Boomsma, Joseph M. Rogers, Rasmus Hartmann-Petersen and Birthe B. Kragelund. (2022) A context-dependent and disordered ubiquitin-binding motif Cellular and molecular life sciences : CMLS 79(9).

64.

Johanna Maarit Koivisto, Nina Rødtness Poulsen, Benedikte Stoklund Larsen, M. G. M. Weibull, Amelie Stein, Fabio Doro, Jakob Rahr Winther, Kresten Lindorff-Larsen and Martin Willemoës. (2022) Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system The Biochemical journal 479(4):479-501.

65.

Juan Luis Pacheco-Garcia, Matteo Cagiada, Kelly Tienne-Matos, Eduardo Salido, Kresten Lindorff-Larsen and Angel L. Pey. (2022) Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation Frontiers in Molecular Biosciences 9.

66.

Kristiane R. Torgeson, Michael W. Clarkson, Daniele Granata, Kresten Lindorff-Larsen, Rebecca Page and Wolfgang Peti. (2022) Conserved conformational dynamics determine enzyme activity Science Advances 8(31).

67.

Magnus Haraldson Høie, Matteo Cagiada, Anders Haagen Beck Frederiksen, Amelie Stein and Kresten Lindorff-Larsen. (2022) Predicting and interpreting large-scale mutagenesis data using analyses of protein stability and conservation Cell Reports 38(2).

68.

Maria Stahl Madsen, Marjoleine F. Broekema, Martin Rønn Madsen, Arjen Koppen, Anouska Borgman, Cathrin Grawe, Elisabeth G. K. Thomsen, Denise Westland, Mariette E. G. Kranendonk, Marian Groot Koerkamp, Nicole Hamers, Alexandre M. J. J. Bonvin, Jose M. Ramos Pittol, Kedar Nath Natarajan, Sander Kersten, Frank C. P. Holstege, Houshang Monajemi, Saskia W. C. van Mil, Michiel Vermeulen, Birthe B. Kragelund, David Cassiman, Susanne Mandrup and Eric Kalkhoven. (2022) PPAR? lipodystrophy mutants reveal intermolecular interactions required for enhancer activation Nature Communications 13.

69.

Mehmet Akdel, Douglas E. Pires, Eduard Porta Pardo, Jürgen Jänes, Arthur O. Zalevsky, Balint Meszaros, Patrick Bryant, Lydia L. Good, Roman A. Laskowski, Gabriele Pozzati, Aditi Shenoy, Wensi Zhu, Petras Kundrotas, Victoria Ruiz Serra, Carlos H. M. Rodrigues, Alistair S. Dunham, David Burke, Neera Borkakoti, Sameer Velankar, Adam Frost, Jérôme Basquin, Kresten Lindorff-Larsen, Alex Bateman, Andrey Kajava, Alfonso Valencia, Sergey Ovchinnikov, Janani Durairaj, David B. Ascher, Janet M. Thornton, Norman E. Davey, Amelie Stein, Arne Elofsson, Tristan Croll and Pedro Beltrao. (2022) A structural biology community assessment of AlphaFold2 applications Nature Structural & Molecular Biology 29(11).

70.

Mette Ahrensback Roesgaard, Jeppe E. Lundsgaard, Estella A. Newcombe, Nina L. Jacobsen, Francesco Pesce, Emil E. Tranchant, Søren Lindemose, Andreas Prestel, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen and Birthe B. Kragelund. (2022) Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties Biomolecules 12(10).

71.

Nicolai Tidemand Johansen, Marta Bonaccorsi, Tone Bengtsen, Andreas Haahr Larsen, Frederik Grønbæk Tidemand, Martin Cramer Pedersen, Pie Huda, Jens Berndtsson, Tamim Darwish, Nageshewar Rao Yepuri, Anne Martel, Thomas Günther Pomorski, Andrea Bertarello, Mark Sansom, Mikaela Rapp, Ramon Crehuet, Tobias Schubeis, Kresten Lindorff-Larsen, Guido Pintacuda and Lise Arleth. (2022) Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation eLife 11.

72.

Nikolaj Riis Christensen, Christian Parsbæk Pedersen, Vita Sereikaite, Jannik Nedergaard Pedersen, Maria Vistrup-Parry, Andreas Toft Sørensen, Daniel Otzen, Kaare Teilum, Kenneth Lindegaard Madsen and Kristian Strømgaard. (2022) Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners iScience 25(2).

73.

Rasmus Krogh Norrild, Kristoffer Enøe Johansson, Charlotte O'Shea, Jens Preben Morth, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2022) Increasing protein stability by inferring substitution effects from high-throughput experiments Cell Reports Methods 2(11).

74.

Sigurd Friis Truelsen, Julie Winkel Missel, Kamil Gotfryd, Per Amstrup Pedersen, Pontus Gourdon, Kresten Lindorff-Larsen and Claus Hélix-Nielsen. (2022) The role of water coordination in the pH-dependent gating of hAQP10 B B A - Biomembranes 1864(1).

75.

Silvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, Paul K. Fyfe, Malo Leprohon, Jie Yang, F. Emil Thomasen, Hauke Winkelmann, Romain Magnez, Alberto G. Conti, Stephan Wilmes, Elizabeth Pohler, Manuel van Gijsel Bonnello, Xavier Thuru, Bruno Quesnel, Fabrice Soncin, Jacob Piehler, Kresten Lindorff-Larsen, Rahul Roychoudhuri, Ignacio Moraga and Suman Mitra. (2022) IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein Science immunology 7(78).

76.

Simone Orioli, Carl G. Henning Hansen and Kresten Lindorff-Larsen. (2022) Transient exposure of a buried phosphorylation site in an autoinhibited protein Biophysical Journal 121(1):91-101.

77.

Yulian Gavrilov, Felix Kümmerer, Simone Orioli, Andreas Prestel, Kresten Lindorff-Larsen and Kaare Teilum. (2022) Double Mutant of Chymotrypsin Inhibitor 2 Stabilized through Increased Conformational Entropy Biochemistry 61(3):160-170.

2021

78.

Ariane Zutz, Louise Hamborg, Lasse Ebdrup Pedersen, Maher M. Kassem, Elena Papaleo, Anna Koza, Markus J. Herrgård, Sheila Ingemann Jensen, Kaare Teilum, Kresten Lindorff-Larsen and Alex Toftgaard Nielsen. (2021) A dual-reporter system for investigating and optimizing protein translation and folding in E. coli Nature Communications 12.

79.

Christian Parsbaek Pedersen, Andreas Prestel and Kaare Teilum. (2021) Software for reconstruction of nonuniformly sampled NMR data Magnetic Resonance in Chemistry 59(3):315-323.

80.

Dennis V. Pedersen, Martin Nors Pedersen, Sofia M. M. Mazarakis, Yong Wang, Kresten Lindorff-Larsen, Lise Arleth and Gregers R. Andersen. (2021) Properdin oligomers adopt rigid extended conformations supporting function eLife 10.

81.

Erik W. Martin, F. Emil Thomasen, Nicole M. Milkovic, Matthew J. Cuneo, Christy R. Grace, Amanda Nourse, Kresten Lindorff-Larsen and Tanja Mittag. (2021) Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation Nucleic Acids Research 49(5):2931-2945.

82.

Estella A. Newcombe, Catarina B. Fernandes, Jeppe E. Lundsgaard, Inna Brakti, Kresten Lindorff-Larsen, Annette E. Langkilde, Karen Skriver and Birthe B. Kragelund. (2021) Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins Biomolecules 11(8).

83.

Eva Madland, Zarah Forsberg, Yong Wang, Kresten Lindorff-Larsen, Axel Niebisch, Jan Modregger, Vincent G. H. Eijsink, Finn L. Aachmann and Gaston Courtade. (2021) Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus Journal of Biological Chemistry 297(4).

84.

Felix Kümmerer, Simone Orioli, David Harding-Larsen, Falk Hoffmann, Yulian Gavrilov, Kaare Teilum and Kresten Lindorff-Larsen. (2021) Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations Journal of Chemical Theory and Computation 17(8):5262-5275.

85.

Francesco Pesce and Kresten Lindorff-Larsen. (2021) Refining conformational ensembles of flexible proteins against small-angle x-ray scattering data Biophysical Journal 120(22):5124-5135.

86.

Frederik Friis Theisen, Lasse Staby, Frederik Grønbæk Tidemand, Charlotte O'Shea, Andreas Prestel, Martin Willemoës, Birthe B. Kragelund and Karen Skriver. (2021) Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding Journal of the American Chemical Society 143(36):14540-14550.

87.

Frederikke Isa Marin, Kristoffer Enøe Johansson, Charlotte O'Shea, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2021) Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold The Journal of Physical Chemistry B 125(40):11141-11149.

88.

Giulio Tesei, João M. Martins, Micha B. A. Kunze, Yong Wang, Ramon Crehuet and Kresten Lindorff-Larsen. (2021) DEER-PREdict: Software for efficient calculation of spin-labeling EPR and NMR data from conformational ensembles PLOS Computational Biology 17(1).

89.

Giulio Tesei, Thea K. Schulze, Ramon Crehuet and Kresten Lindorff-Larsen. (2021) Accurate model of liquid-liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties Proceedings of the National Academy of Sciences of the United States of America 118(44).

90.

Johnny Birch, Sanaullah Khan, Mikkel Madsen, Christian Kjeldsen, Marie Sofie Møller, Emil G. P. Stender, Günther H. J. Peters, Jens Ø. Duus, Birthe B. Kragelund and Birte Svensson. (2021) Binding Sites for Oligosaccharide Repeats from Lactic Acid Bacteria Exopolysaccharides on Bovine ß-Lactoglobulin Identified by NMR Spectroscopy ACS Omega 6(13):9039-9052.

91.

Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetic, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy Burman, Rituparna Samanta, Shannon T. Smith, Frank Teets, Johanna K. S. Tiemann, Andrew Watkins, Hope Woods, Brahm J. Yachnin, Christopher D. Bahl, Chris Bailey-Kellogg, David Baker, Rhiju Das, Frank DiMaio, Sagar D. Khare, Tanja Kortemme, Jason W. Labonte, Kresten Lindorff-Larsen, Jens Meiler, William Schief, Ora Schueler-Furman, Justin B. Siegel, Amelie Stein, Vladimir Yarov-Yarovoy, Brian Kuhlman, Andrew Leaver-Fay, Dominik Gront, Jeffrey J. Gray and Richard Bonneau. (2021) Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks Nature Communications 12.

92.

Kaare Teilum, Johan G. Olsen and Birthe B. Kragelund. (2021) On the specificity of protein-protein interactions in the context of disorder Biochemical Journal 478(11):2035-2050.

93.

Kaituo Wang, Robert Dagil, Thomas Lavstsen, Sandeep K Misra, Charlotte B. Spliid, Yong Wang, Tobias Gustavsson, Daniel R. Sandoval, Elena Ethel Vidal-Calvo, Swati Choudhary, Mette Ø. Agerbaek, Kresten Lindorff-Larsen, Morten A. Nielsen, Thor G. Theander, Joshua S Sharp, Thomas Mandel Clausen, Pontus Gourdon and Ali Salanti. (2021) Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding Nature Communications 12(1).

94.

Katharina Weinhäupl, Yong Wang, Audrey Hessel, Martha Brennich, Kresten Lindorff-Larsen and Paul Schanda. (2021) Architecture and assembly dynamics of the essential mitochondrial chaperone complex TIM9·10·12 Structure 29(9):1065-1073.e4.

95.

Katrine Bugge, Lasse Staby, Edoardo Salladini, Rasmus G. Falbe-Hansen, Birthe B. Kragelund and Karen Skriver. (2021) aa-Hub domains and intrinsically disordered proteins: a decisive combo Journal of Biological Chemistry 296.

96.

Kresten Lindorff-Larsen and Birthe B. Kragelund. (2021) On the Potential of Machine Learning to Examine the Relationship Between Sequence, Structure, Dynamics and Function of Intrinsically Disordered Proteins Journal of Molecular Biology 433(20).

97.

Kresten Lindorff-Larsen and Kaare Teilum. (2021) Linking thermodynamics and measurements of protein stability Protein engineering, design & selection : PEDS 34.

98.

Lasse Staby, Amanda D. Due, Micha Ben Achim Kunze, Maria Louise Mønster Jørgensen, Karen Skriver and Birthe B. Kragelund. (2021) Flanking Disorder of the Folded aa-Hub Domain from Radical Induced Cell Death1 Affects Transcription Factor Binding by Ensemble Redistribution: Flanking disorder tunes the RCD1-RST ensemble Journal of Molecular Biology 433(24).

99.

Lasse Staby, Katherine R. Kemplen, Amelie Stein, Michael Ploug, Jane Clarke, Karen Skriver, Pétur O. Heidarsson and Birthe B. Kragelund. (2021) Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry Cellular and molecular life sciences : CMLS 78:2263-2278.

100.

Lasse Staby, Katrine Bugge, Rasmus Greve Falbe-Hansen, Edoardo Salladini, Karen Skriver and Birthe B. Kragelund. (2021) Connecting the aa-hubs: same fold, disordered ligands, new functions Cell Communication and Signaling 19.

101.

Lise M. Sjøgaard-Frich, Andreas Prestel, Emilie S. Pedersen, Marc Severin, Kristian Kølby Kristensen, Johan G. Olsen, Birthe B. Kragelund and Stine Falsig Pedersen. (2021) Dynamic Na+/H+ exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation eLife 10.

102.

Louise Hamborg, Daniele Granata, Johan G. Olsen, Jennifer Virginia Roche, Lasse Ebdrup Pedersen, Alex Toftgaard Nielsen, Kresten Lindorff-Larsen and Kaare Teilum. (2021) Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli Communications Biology 4.

103.

Matteo Cagiada, Kristoffer E. Johansson, Audrone Valanciute, Sofie V. Nielsen, Rasmus Hartmann-Petersen, Jun J. Yang, Douglas M. Fowler, Amelie Stein and Kresten Lindorff-Larsen. (2021) Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance Molecular Biology and Evolution 38(8):3235-3246.

104.

Matteo Lambrughi, Emiliano Maiani, Burcu Aykac Fas, Gary S. Shaw, Birthe B. Kragelund, Kresten Lindorff-Larsen, Kaare Teilum, Gaetano Invernizzi and Elena Papaleo. (2021) Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs Frontiers in Molecular Biosciences 8.

105.

Mia L. Abramsson, Cagla Sahin, Jonathan T. S. Hopper, Rui M. M. Branca, Jens Danielsson, Mingming Xu, Shane A. Chandler, Nicklas Österlund, Leopold L. Ilag, Axel Leppert, Joana Costeira-Paulo, Lisa Lang, Kaare Teilum, Arthur Laganowsky, Justin L. P. Benesch, Mikael Oliveberg, Carol V. Robinson, Erik G. Marklund, Timothy M. Allison, Jakob R. Winther and Michael Landreh. (2021) Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry JACS Au 1(12):2385-2393.

106.

Mustapha Carab Ahmed, Line K. Skaanning, Alexander Jussupow, Estella A. Newcombe, Birthe B. Kragelund, Carlo Camilloni, Annette E. Langkilde and Kresten Lindorff-Larsen. (2021) Refinement of a-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods Frontiers in Molecular Biosciences 8.

107.

Noah Kassem, Raul Araya-Secchi, Katrine Bugge, Abigail Barclay, Helena Steinocher, Adree Khondker, Yong Wang, Aneta J. Lenard, Jochen Bürck, Cagla Sahin, Anne S. Ulrich, Michael Landreh, Martin Cramer Pedersen, Maikel C. Rheinstädter, Per Amstrup Pedersen, Kresten Lindorff-Larsen, Lise Arleth and Birthe B. Kragelund. (2021) Order and disorder - An integrative structure of the full-length human growth hormone receptor Science Advances 7(27).

108.

Peter S. Millard, Birthe B. Kragelund and Meike Burow. (2021) Evolution of A bHLH Interaction Motif International Journal of Molecular Sciences 22(1).

109.

Sandro Bottaro, Giovanni Bussi and Kresten Lindorff-Larsen. (2021) Conformational Ensembles of Noncoding Elements in the SARS-CoV-2 Genome from Molecular Dynamics Simulations Journal of the American Chemical Society 143(22):8333-8343.

110.

Sarah F. Ruidiaz, Jesper E. Dreier, Rasmus Hartmann-Petersen and Birthe B. Kragelund. (2021) The disordered PCI-binding human proteins CSNAP and DSS1 have diverged in structure and function Protein Science 30(10):2069-2082.

111.

Sarah K. Gersing, Yong Wang, Martin Grønbæk-Thygesen, Caroline Kampmeyer, Lene Clausen, Martin Willemoës, Claes Andréasson, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2021) Mapping the degradation pathway of a disease-linked aspartoacylase variant PLOS Genetics 17(4).

112.

Simon Erlendsson and Kaare Teilum. (2021) Binding Revisited - Avidity in Cellular Function and Signaling Frontiers in Molecular Biosciences 7.

113.

Sofie V. Nielsen, Rasmus Hartmann-Petersen, Amelie Stein and Kresten Lindorff-Larsen. (2021) Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition PLOS Genetics 17(4).

114.

Stefan Hervø-Hansen, Casper Højgaard, Kristoffer Enøe Johansson, Yong Wang, Khadija Wahni, David Young, Joris Messens, Kaare Teilum, Kresten Lindorff-Larsen and Jakob Rahr Winther. (2021) Charge Interactions in a Highly Charge-Depleted Protein Journal of the American Chemical Society 143(6):2500-2508.

115.

Stéphanie Jephthah, Francesco Pesce, Kresten Lindorff-Larsen and Marie Skepö. (2021) Force Field Effects in Simulations of Flexible Peptides with Varying Polyproline II Propensity Journal of Chemical Theory and Computation 17(10):6634-6646.

2020

116.

Pernille Seiffert, Katrine Bugge, Mads Nygaard, Gitte W. Haxholm, Jacob H. Martinsen, Martin N. Pedersen, Lise Arleth, Wouter Boomsma and Birthe B. Kragelund. (2020) Orchestration of signaling by structural disorder in class 1 cytokine receptors Cell Communication and Signaling 18(1).

117.

Tone Bengtsen, Søren Roi Midtgaard, Viktor Lindahl Holm, Lisbeth Ravnkilde Kjølbye, Nicolai Tidemand Johansen, Giulio Tesei, Sandro Bottaro, Birgit Schiøtt, Lise Arleth and Kresten Lindorff-Larsen. (2020) Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations. eLife 9.

118.

Lise Arleth, Nicolai T. Johansen, Tone Bengtsen, Andreas Haahr Larsen, Frederik Tidemand, Thomas Pomorski and Kresten Lindorff-Larsen. (2020) Small-angle Neutron Scattering Shows that the Solution Structures of the Bacterial Mg2+-Channel CorA are Overall Similar with and without Mg2+ Bound Biophysical Journal 118:12A-12A.

119.

Raul Araya-Secchi, Katrine Bugge, Birthe B. Kragelund and Lise Arleth. (2020) Exploring the Protein-Membrane Interactions on the Intracellular Side of PRLR Biophysical Journal 118:57A-57A.

120.

Ruth Hendus-Altenburger, Jens Vogensen, Emilie Skotte Pedersen, Alessandra Luchini, Raul Araya-Secchi, Anne H. Bendsoe, Nanditha Shyam Prasad, Andreas Prestel, Marite Cardenas, Elena Pedraz-Cuesta, Lise Arleth, Stine Helene Falsig Pedersen and Birthe B. Kragelund. (2020) The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity Communications Biology 3(1).

121.

Aina Nedal, Synnøve B. Ræder, Bjørn Dalhus, Emily Helgesen, Rune J. Forstrøm, Kim Lindland, Balagra K. Sumabe, Jacob H. Martinsen, Birthe B. Kragelund, Kirsten Skarstad, Magnar Bjørås and Marit Otterlei. (2020) Peptides containing the PCNA interacting motif APIM bind to the ß-clamp and inhibit bacterial growth and mutagenesis Nucleic Acids Research 48(10):5540-5554.

122.

Amanda B. Abildgaard, Sarah K. Gersing, Sven Larsen-Ledet, Sofie V. Nielsen, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2020) Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome Biomolecules 10(8).

123.

Amanda B. Abildgaard, Sarah K. Gersing, Sven Larsen-Ledet, Sofie V. Nielsen, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2020) Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome Biomolecules 10(8).

124.

Amanda B. Abildgaard, Sarah K. Gersing, Sven Larsen-Ledet, Sofie V. Nielsen, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2020) Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome Biomolecules 10(8).

125.

Andrea Sottini, Alessandro Borgia, Madeleine B. Borgia, Katrine Bugge, Daniel Nettels, Aritra Chowdhury, Pétur O. Heidarsson, Franziska Zosel, Robert B. Best, Birthe B. Kragelund and Benjamin Schuler. (2020) Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes Nature Communications 11.

126.

Andreas Haahr Larsen, Yong Wang, Sandro Bottaro, Sergei Grudinin, Lise Arleth and Kresten Lindorff-Larsen. (2020) Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution P L o S Computational Biology 16(4).

127.

Birthe B. Kragelund, Andreas Prestel, Nanna Wickmann, Joao Martins, Wouter Boomsma, Lasse Staby, Ruth Hendus-Altenburger and Karen Skriver. (2020) Context Matters in Disorder Based Protein Communication Biophysical Journal 118:491A.

128.

Caroline Kampmeyer, Jens V. Johansen, Christian Holmberg, Magnus Karlson, Sarah K. Gersing, Heloisa N. Bordallo, Birthe B. Kragelund, Mathilde Hauge Lerche, Isabelle Jourdain, Jakob R. Winther and Rasmus Hartmann-Petersen. (2020) Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water A C S Synthetic Biology 9(4):733-748.

129.

Ersoy Cholak, Katrine Bugge, Adree Khondker, Kimmie Gauger, Elena Pedraz-Cuesta, Morten Enghave Pedersen, Saskia Bucciarelli, Bente Vestergaard, Stine F. Pedersen, Maikel C. Rheinstädter, Annette Eva Langkilde and Birthe B. Kragelund. (2020) Avidity within the N-terminal anchor drives a-synuclein membrane interaction and insertion FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34(6):7462-7482.

130.

Frederik Grønbæk Tidemand, Henrik Østergaard, Michael Ploug, Birthe B. Kragelund and Lise Arleth. (2020) Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer Biochimica et Biophysica Acta - Biomembranes 1862(6).

131.

Helena Gásdal Karstensen, Nanna Dahl Rendtorff, Lone Sandbjerg Hindbæk, Roberto Colombo, Amelie Stein, Niels Holtum Birkebæk, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Allan Thomas Højland, Michael Bjørn Petersen and Lisbeth Tranebjærg. (2020) Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome European Journal of Medical Genetics 63(3).

132.

Iva Sucec, Yong Wang, Ons Dakhlaoui, Katharina Weinhäupl, Tobias Jores, Doriane Costa, Audrey Hessel, Martha Brennich, Doron Rapaport, Kresten Lindorff-Larsen, Beate Bersch and Paul Schanda. (2020) Structural basis of client specificity in mitochondrial membrane-protein chaperones Science Advances 6(51).

133.

James S. Fraser, Kresten Lindorff-Larsen and Massimiliano Bonomi. (2020) What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data? Journal of Chemical Information and Modeling 60(5):2410-2412.

134.

João Henriques and Kresten Lindorff-Larsen. (2020) Protein Dynamics Enables Phosphorylation of Buried Residues in Cdk2/Cyclin-A-Bound p27 Biophysical Journal 119(10):2010-2018.

135.

Katrine Bugge, Inna Brakti, Catarina B. Fernandes, Jesper E. Dreier, Jeppe E. Lundsgaard, Johan G. Olsen, Karen Skriver and Birthe B. Kragelund. (2020) Interactions by Disorder - A Matter of Context Frontiers in Molecular Biosciences 7.

136.

Lene Clausen, Amelie Stein, Martin Grønbæk-Thygesen, Lasse Nygaard, Cecilie L. Søltoft, Sofie V. Nielsen, Michael Lisby, Tommer Ravid, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2020) Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation PLOS Genetics 16(11).

137.

Line K. Skaanning, Angelo Santoro, Thomas Skamris, Jacob Hertz Martinsen, Anna Maria D’Ursi, Saskia Bucciarelli, Bente Vestergaard, Katrine Bugge, Annette Eva Langkilde and Birthe B. Kragelund. (2020) The Non-Fibrillating N-Terminal of a-Synuclein Binds and Co-Fibrillates with Heparin Biomolecules 10(8).

138.

Louise Hamborg, Emma Wenzel Horsted, Kristoffer Enøe Johansson, Martin Willemoës, Kresten Lindorff-Larsen and Kaare Teilum. (2020) Global analysis of protein stability by temperature and chemical denaturation Analytical Biochemistry 605.

139.

Michael Maglegaard Jepsen, Douglas M. Fowler, Rasmus Hartmann-Petersen, Amelie Stein and Kresten Lindorff-Larsen. (2020) Classifying disease-associated variants using measures of protein activity and stability Protein Homeostasis Diseases - Mechanisms and Novel Therapies:91-107.

140.

Mustapha Carab Ahmed, Ramon Crehuet and Kresten Lindorff-Larsen. (2020) Computing, Analyzing, and Comparing the Radius of Gyration and Hydrodynamic Radius in Conformational Ensembles of Intrinsically Disordered Proteins Intrinsically Disordered Proteins - Methods and Protocols:429-445.

141.

Nikolaj R. Christensen, Marta De Luca, Michael B. Lever, Mette Richner, Astrid B. Hansen, Gith Noes-Holt, Kathrine L. Jensen, Mette Rathje, Dennis Bo Jensen, Simon Erlendsson, Christian R.O. Bartling, Ina Ammendrup-Johnsen, Sofie E. Pedersen, Michèle Schönauer, Klaus B. Nissen, Søren R. Midtgaard, Kaare Teilum, Lise Arleth, Andreas T. Sørensen, Anders Bach, Kristian Strømgaard, Claire F. Meehan, Christian B. Vægter, Ulrik Gether and Kenneth L. Madsen. (2020) A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain EMBO Molecular Medicine 12(6).

142.

Noah Kassem, Maher M. Kassem, Stine F. Pedersen, Per Amstrup Pedersen and Birthe B. Kragelund. (2020) Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies Biochimica et Biophysica Acta - Biomembranes 1862(6).

143.

Peter S. Millard, Katrine Bugge, Riccardo Marabini, Wouter Boomsma, Meike Burow and Birthe B. Kragelund. (2020) IDDomainSpotter: Compositional bias reveals domains in long disordered protein regions—Insights from transcription factors Protein Science 29(1):169-183.

144.

Punam Sonar, Luca Bellucci, Alessandro Mossa, Pétur O. Heidarsson, Birthe B. Kragelund and Ciro Cecconi. (2020) Effects of Ligand Binding on the Energy Landscape of Acyl-CoA-Binding Protein Biophysical Journal 119(9):1821-1832.

145.

Sandro Bottaro, Parker J. Nichols, Beat Vögeli, Michele Parrinello and Kresten Lindorff-Larsen. (2020) Integrating NMR and simulations reveals motions in the UUCG tetraloop Nucleic Acids Research 48(11):5839-5848.

146.

Sandro Bottaro, Tone Bengtsen and Kresten Lindorff-Larsen. (2020) Integrating Molecular Simulation and Experimental Data: A Bayesian/Maximum Entropy Reweighting Approach Structural Bioinformatics - Methods and Protocols:219-240.

147.

Shanshan Wu, Tam T. T. N. Nguyen, Olga V. Moroz, Johan P. Turkenburg, Jens E. Nielsen, Keith S. Wilson, Kasper D. Rand and Kaare Teilum. (2020) Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis PeerJ 8.

148.

Simone Orioli, Andreas Haahr Larsen, Sandro Bottaro and Kresten Lindorff-Larsen. (2020) How to learn from inconsistencies: Integrating molecular simulations with experimental data Computational Approaches for Understanding Dynamical Systems - Protein Folding and Assembly:123-176.

149.

Sofie V. Nielsen, Signe M. Schenstrøm, Caspar E. Christensen, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2020) Protein destabilization and degradation as a mechanism for hereditary disease Protein Homeostasis Diseases - Mechanisms and Novel Therapies:111-125.

2019

150.

Murillo L. Martins, Alexander B. Dinitzen, Eugene Mamontov, Svemir Rudic, Jose E. M. Pereira, Rasmus Hartmann-Petersen, Kenneth W. Herwig and Heloisa N. Bordallo. (2019) Water dynamics in MCF-7 breast cancer cells: a neutron scattering descriptive study Scientific Reports 9.

151.

Michael Lückmann, Mette Trauelsen, Marie A Bentsen, Tinne A D Nissen, Joao Martins, Zohreh Fallah, Mads M Nygaard, Elena Papaleo, Kresten Lindorff-Larsen, Thue W Schwartz and Thomas M Frimurer. (2019) Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1 Proceedings of the National Academy of Sciences of the United States of America 116(14):7123-7128.

152.

Ersoy Cholak, Saskia Bucciarelli, Katrine Bugge, Nicolai Tidemand Johansen, Bente Vestergaard, Lise Arleth, Birthe B Kragelund and Annette E Langkilde. (2019) Distinct a-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior Biochemistry 58(50):5052-5065.

153.

Sébastien Morin, Troels E. Linnet, Mathilde Lescanne, Paul Schanda, Gary S. Thompson, Martin Tollinger, Kaare Teilum, Stéphane Gagné, Dominique Marion, Christian Griesinger, Martin Blackledge and Edward J. D'Auvergne. (2019) Corrigendum: Relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data (Bioinformatics (2014) DOI: 10.1093/bioinformatics/btu166) Bioinformatics 35(20):4205.

154.

Albert Escobedo, Busra Topal, Micha B. A. Kunze, Juan Aranda, Giulio Chiesa, Daniele Mungianu, Ganeko Bernardo-Seisdedos, Bahareh Eftekharzadeh, Margarida Gairí, Roberta Pierattelli, Isabella C. Felli, Tammo Diercks, Oscar Millet, Jesús García, Modesto Orozco, Ramon Crehuet, Kresten Lindorff-Larsen and Xavier Salvatella. (2019) Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor Nature Communications 10.

155.

Amanda B. Abildgaard, Amelie Stein, Sofie V. Nielsen, Katrine Schultz-Knudsen, Elena Papaleo, Amruta Shrikhande, Eva R Hoffmann, Inge Bernstein, Anne-Marie Gerdes, Masanobu Takahashi, Chikashi Ishioka, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2019) Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome eLife 8.

156.

Amelie Stein, Douglas M. Fowler, Rasmus Hartmann-Petersen and Kresten Lindorff-Larsen. (2019) Biophysical and Mechanistic Models for Disease-Causing Protein Variants Trends in Biochemical Sciences 44(7):575-588.

157.

Andrea Cesari, Sandro Bottaro, Kresten Lindorff-Larsen, Pavel Banás, Jiri Sponer and Giovanni Bussi. (2019) Fitting Corrections to an RNA Force Field Using Experimental Data Journal of Chemical Theory and Computation 15(6):3425-3431.

158.

Andreas Prestel, Nanna Wichmann, Joao M. Martins, Riccardo Marabini, Noah Kassem, Sebastian S. Broendum, Marit Otterlei, Olaf Nielsen, Martin Willemoës, Michael Ploug, Wouter Boomsma and Birthe B. Kragelund. (2019) The PCNA interaction motifs revisited: thinking outside the PIP-box Cellular and Molecular Life Sciences 76(24):4923-4943.

159.

Anne Kathrine Nielsen, Ingvar R. Möller, Yong Wang, Søren G. F. Rasmussen, Kresten Lindorff-Larsen, Kasper D. Rand and Claus J. Loland. (2019) Substrate-induced conformational dynamics of the dopamine transporter Nature Communications 10.

160.

Anne Kathrine Nielsen, Ingvar R. Möller, Yong Wang, Søren G. F. Rasmussen, Kresten Lindorff-Larsen, Kasper D. Rand and Claus J. Loland. (2019) Substrate-induced conformational dynamics of the dopamine transporter Nature Communications 10.

161.

Anne Kathrine Nielsen, Ingvar R. Möller, Yong Wang, Søren G. F. Rasmussen, Kresten Lindorff-Larsen, Kasper D. Rand and Claus J. Loland. (2019) Substrate-induced conformational dynamics of the dopamine transporter Nature Communications 10.

162.

Carolina Cragnell, Lasse Staby, Samuel Lenton, Birthe B. Kragelund and Marie Skepö. (2019) Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions Biomolecules 9(5).

163.

Dennis V. Pedersen, Trine Amalie Fogh Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram, Rasmus Kjeldsen Jensen, Sofia M. M. Mazarakis, Margot Revel, Carine El Sissy, Steen V. Petersen, Kresten Lindorff-Larsen, Steffen Thiel, Nick Stub Laursen, Véronique Fremeaux-Bacchi and Gregers Rom Andersen. (2019) Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System Frontiers in Immunology 10.

164.

Emil G. P. Stender, Johnny Birch, Christian Kjeldsen, Lau D. Nielsen, Jens Ø. Duus, Birthe B. Kragelund and Birte Svensson. (2019) Alginate Trisaccharide Binding Sites on the Surface of ß-Lactoglobulin Identified by NMR Spectroscopy: Implications for Molecular Network Formation ACS Omega 4(4):6165-6174.

165.

Ida Marie Zobbe Sjøgaard, Simon Bressendorff, Andreas Prestel, Swathi Kausika, Emilie Oksbjerg, Birthe B. Kragelund and Peter Brodersen. (2019) The transmembrane autophagy cargo receptors ATI1 and ATI2 interact with ATG8 through intrinsically disordered regions with distinct biophysical properties Biochemical Journal 476(3):449-465.

166.

Kresten Lindorff-Larsen. (2019) Dissecting the statistical properties of the linear extrapolation method of determining protein stability Protein engineering, design & selection : PEDS 32(10):471-479.

167.

Lau D Nielsen, Mads M. Foged, Anastasia Albert, Andreas B. Bertelsen, Cecilie L Søltoft, Samuel D. Robinson, Steen Vang Petersen, Anthony W. Purcell, Baldomero M. Olivera, Raymond S. Norton, Terje Vasskog, Helena Safavi-Hemami, Kaare Teilum and Lars Ellgaard. (2019) The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework The Journal of Biological Chemistry 294(22):8745-8759.

168.

Lau Dalby Nielsen, Christian Parsbæk Pedersen, Simon Erlendsson and Kaare Teilum. (2019) The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor Structure 27(7):1071-1081, e1-e5.

169.

Lene Clausen, Amanda Bering Abildgaard, Sarah K. Gersing, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2019) Protein stability and degradation in health and disease Molecular Chaperones in Human Disorders:61-83.

170.

Li He, Emily B. Cohen, Anne P. B. Edwards, Juliana Xavier-Ferrucio, Katrine Bugge, Ross S. Federman, Devin Absher, Richard M. Myers, Birthe B. Kragelund, Diane S. Krause and Daniel DiMaio. (2019) Transmembrane Protein Aptamer Induces Cooperative Signaling by the EPO Receptor and the Cytokine Receptor ß-Common Subunit iScience 17:167-181.

171.

Lise Friis Christensen, Lasse Staby, Katrine Bugge, Charlotte O'Shea, Birthe B. Kragelund and Karen Skriver. (2019) Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome Scientific Reports 9.

172.

Martin Cramer Pedersen, Yong Wang, Frederik Grønbæk Tidemand, A. Martel, Kresten Lindorff-Larsen and Lise Arleth. (2019) PSX, Protein-Solvent Exchange: software for calculation of deuterium-exchange effects in small-angle neutron scattering measurements from protein coordinates Journal of Applied Crystallography 52(6):1427-1436.

173.

Massimiliano Bonomi, Giovanni Bussi, Carlo Camilloni, Gareth A. Tribello, Pavel Banas, Alessandro Barducci, Mattia Bernetti, Peter G. Bolhuis, Sandro Bottaro, Davide Branduardi, Riccardo Capelli, Paolo Carloni, Michele Ceriotti, Andrea Cesari, Haochuan Chen, Wei Chen, Francesco Colizzi, Sandip De, Marco De La Pierre, Davide Donadio, Viktor Drobot, Bernd Ensing, Andrew L. Ferguson, Marta Filizola, James S. Fraser, Haohao Fu, Piero Gasparotto, Francesco Luigi Gervasio, Federico Giberti, Alejandro Gil-Ley, Toni Giorgino, Gabriella T. Heller, Glen M. Hocky, Marcella Iannuzzi, Michele Invernizzi, Kim E. Jelfs, Alexander Jussupow, Evgeny Kirilin, Alessandro Laio, Vittorio Limongelli, Kresten Lindorff-Larsen, Thomas Lohr, Fabrizio Marinelli, Layla Martin-Samos, Matteo Masetti, Ralf Meyer, Angelos Michaelides, Carla Molteni, Tetsuya Morishita, Marco Nava, Cristina Paissoni, Elena Papaleo, Michele Parrinello, Jim Pfaendtner, Pablo Piaggi, GiovanniMaria Piccini, Adriana Pietropaolo, Fabio Pietrucci, Silvio Pipolo, Davide Provasi, David Quigley, Paolo Raiteri, Stefano Raniolo, Jakub Rydzewski, Matteo Salvalaglio, Gabriele Cesare Sosso, Vojtech Spiwok, Jiri Sponer, David W. H. Swenson, Pratyush Tiwary, Omar Valsson, Michele Vendruscolo, Gregory A. Voth and Andrew White. (2019) Promoting transparency and reproducibility in enhanced molecular simulations Nature Methods 16(8):670-673.

174.

Noureldin Saleh, Yong Wang, Poul Nissen and Kresten Lindorff-Larsen. (2019) Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions Physical Chemistry Chemical Physics 21(39):21991-21995.

175.

Peter S. Millard, Birthe B. Kragelund and Meike Burow. (2019) R2R3 MYB Transcription Factors - Functions outside the DNA-Binding Domain Trends in Plant Science 24(10):934-946.

176.

Peter S. Millard, Konrad Weber, Birthe B. Kragelund and Meike Burow. (2019) Specificity of MYB interactions relies on motifs in ordered and disordered contexts Nucleic Acids Research 47(18):9592-9608.

177.

Ramon Crehuet, Pedro J. Buigues, Xavier Salvatella and Kresten Lindorff-Larsen. (2019) Bayesian-Maximum-Entropy Reweighting of IDP Ensembles Based on NMR Chemical Shifts Entropy 21(9).

178.

Rasmus Scheller, Amelie Stein, Sofie V. Nielsen, Frederikke I. Marin, Anne-Marie Gerdes, Miriam Di Marco, Elena Papaleo, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2019) Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations Human Mutation 40(4):444-457.

179.

Ruth Hendus-Altenburger, Catarina B. Fernandes, Katrine Bugge, Micha B. A. Kunze, Wouter Boomsma and Birthe B. Kragelund. (2019) Random coil chemical shifts for serine, threonine and tyrosine phosphorylation over a broad pH range Journal of Biomolecular NMR 73(12):713–725.

180.

Ruth Hendus-Altenburger, Xinru Wang, Lise M. Sjøgaard-Frich, Elena Pedraz Cuesta, Sarah R. Sheftic, Anne H. Bendsøe, Rebecca Page, Birthe B. Kragelund, Stine F Pedersen and Wolfgang Peti. (2019) Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin Nature Communications 10.

181.

S. Jephthah, L. Staby, B. B. Kragelund and M. Skepö. (2019) Temperature Dependence of Intrinsically Disordered Proteins in Simulations: What are We Missing? Journal of Chemical Theory and Computation 15(4):2672-2683.

182.

Sandro Bottaro, Giovanni Bussi, Giovanni Pinamonti, Sabine Reisser, Wouter Boomsma and Kresten Lindorff-Larsen. (2019) Barnaba: software for analysis of nucleic acid structures and trajectories RNA 25(2):219-231.

183.

Simon Erlendsson, Thor Seneca Thorsen, Georges Vauquelin, Ina Ammendrup-Johnsen, Volker Wirth, Karen L. Martinez, Kaare Teilum, Ulrik Gether and Kenneth Lindegaard Madsen. (2019) Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets eLife 8:1-27.

184.

Yong Wang, Noureldin Saleh, Xiakun Chu and Kresten Lindorff-Larsen. (2019) A Multi-State Coarse-Grained Simulation Model Captures Conformational Cycling in P-Type ATPases Biophysical Journal 116:300a.

2018

185.

Joao Henriques, Lise Arleth, Kresten Lindorff-Larsen and Marie Skepo. (2018) On the Calculation of SAXS Profiles of Folded and Intrinsically Disordered Proteins from Computer Simulations Journal of Molecular Biology 430:2521-2539.

186.

Ganesan Senthil Kumar, Michael W. Clarkson, Micha Ben Achim Kunze, Daniele Granata, A. Joshua Wand, Kresten Lindorff-Larsen, Rebecca Page and Wolfgang Peti. (2018) Dynamic activation and regulation of the mitogen-activated protein kinase p38 Proceedings of the National Academy of Sciences of the United States of America 115(18):4655-4660.

187.

Sandro Bottaro, Giovanni Bussi, Scott D. Kennedy, Douglas H. Turner and Kresten Lindorff-Larsen. (2018) Conformational ensembles of RNA oligonucleotides from integrating NMR and molecular simulations Science Advances 4(5).

188.

Alessandro Borgia, Madeleine B. Borgia, Katrine Østergaard Bugge, Vera M. Kissling, Pétur O. Heidarsson, Catarina B. Fernandes, Andrea Sottini, Andrea Soranno, Karin J. Buholzer, Daniel Nettels, Birthe Brandt Kragelund, Robert B. Best and Benjamin Schuler. (2018) Extreme disorder in an ultrahigh-affinity protein complex Nature 555:61-66.

189.

Tone Bengtsen, Viktor Lindahl Holm, Søren Roi Midtgaard, Lise Arleth and Kresten Lindorff-Larsen. (2018) A Combined Simulation and SAXS Study of the Dynamics of Lipid Nanodiscs Biophysical Journal 114:559A-559A.

190.

Signe Marie Schenstrøm, Caio A. Rebula, Michael H. Tatham, Ruth Hendus-Altenburger, Isabelle Jourdain, Ronald T. Hay, Birthe B. Kragelund and Rasmus Hartmann-Petersen. (2018) Expanded Interactome of the Intrinsically Disordered Protein Dss1 Cell Reports 25(4):862-870.

191.

Andreas Prestel, Katrine Bugge, Lasse Staby, Ruth Hendus-Altenburger and Birthe B. Kragelund. (2018) Characterization of Dynamic IDP Complexes by NMR Spectroscopy Intrinsically Disordered Proteins:193-226.

192.

Dhawal Choudhary, Birthe B. Kragelund, Pétur O Heidarsson and Ciro Cecconi. (2018) The Complex Conformational Dynamics of Neuronal Calcium Sensor-1: A Single Molecule Perspective Frontiers in Molecular Neuroscience 11:1-8.

193.

Elena Papaleo, Carlo Camilloni, Kaare Teilum, Michele Vendruscolo and Kresten Lindorff-Larsen. (2018) Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs PeerJ 6:1-24.

194.

Jill J. Bouchard, Joel H. Otero, Daniel C. Scott, Elzbieta Szulc, Erik W. Martin, Nafiseh Sabri, Daniele Granata, Melissa R. Marzahn, Kresten Lindorff-Larsen, Xavier Salvatella, Brenda A. Schulman and Tanja Mittag. (2018) Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments Molecular Cell 72(1):19-36, e1-e8.

195.

Katharina Weinhaupl, Caroline Lindau, Audrey Hessel, Yong Wang, Conny Schültze, Tobias Jores, Laura Melchionda, Birgit Schönfisch, Hubert Kalbacher, Beate Bersch, Doron Rapaport, Martha Brennich, Kresten Lindorff-Larsen, Nils Wiedemann and Paul Schanda. (2018) Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space Cell 175(5):1365-1379, e25.

196.

Katrine Østergaard Bugge, Lasse Staby, Katherine Rosemary Kemplen, Charlotte O'Shea, Sidsel Krogh Bendsen, Mikael Kryger Jensen, Johan Gotthardt Olsen, Karen Skriver and Birthe Brandt Kragelund. (2018) Structure of radical-induced cell death1 hub domain reveals a common aa-scaffold for disorder in transcriptional networks Structure 26(5):734-746.

197.

Kim Krighaar Rasmussen, Maria Hansen Falkesgaard, Malene Winther, Nikolaj Kulahin Roed, Christine Louise Ander Quistgaard, Marie Nygaard Teisen, Sofie Marie Edslev, David Leander Petersen, Ali Aljubouri, Claus Christensen, Peter Waaben Thulstrup, Leila Lo Leggio, Kaare Teilum and Peter Schledermann Walmod. (2018) NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor Scientific Reports 8.

198.

Kristian Kølby Kristensen, Søren Roi Midtgaard, Simon Mysling, Oleg Kovrov, Lars Bo Hansen, Nicholas Skar-Gislinge, Anne P. Beigneux, Birthe Brandt Kragelund, Gunilla Olivecrona, Stephen G. Young, Thomas J. D. Jørgensen, Loren G. Fong and Michael Ploug. (2018) A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase Proceedings of the National Academy of Sciences of the United States of America 115(26):E6020-E6029.

199.

Kristoffer Enøe Johansson and Kresten Lindorff-Larsen. (2018) Structural heterogeneity and dynamics in protein evolution and design Current Opinion in Structural Biology 48:157-163.

200.

Lotte Emilie Boyhus, Mia Danielsen, Nina Smidt Bengtson, Micha Ben Achim Kunze, Xavier Kubiak, Tjerk J. Sminia, Jacob Hartvig Løper, Phuong Thu Tran, Kresten Lindorff-Larsen, Søren G.F. Rasmussen, Jesper Mosolff Mathiesen and Daniel Sejer Pedersen. (2018) Gs protein peptidomimetics as allosteric modulators of the ß2-adrenergic receptor RSC Advances 8(4):2219-2228.

201.

Maher M. Kassem, Lars B. Christoffersen, Andrea Cavalli and Kresten Lindorff-Larsen. (2018) Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts Scientific Reports 8.

202.

Mustapha Carab Hussein Ahmed, Elena Papaleo and Kresten Lindorff-Larsen. (2018) How well do force fields capture the strength of salt bridges in proteins? PeerJ 6.

203.

Paul Santner, Joao Miguel da Silva Martins, Caroline Kampmeyer, Rasmus Hartmann-Petersen, Jonas S. Laursen, Amelie Stein, Christian A Olsen, Isaiah T Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants Biochemistry 57(41):5957-5968.

204.

Paul Santner, João Miguel da Silva Martins, Jonas S. Laursen, Lars Behrendt, Leise Riber, Christian A Olsen, Isaiah T. Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel Biochemistry 57(41):5949-5956.

205.

Robert B. Best and Kresten Lindorff-Larsen. (2018) Editorial overview: Theory and simulation: Interpreting experimental data at the molecular level Current Opinion in Structural Biology 49:iv-v.

206.

Sandro Bottaro and Kresten Lindorff-Larsen. (2018) Biophysical experiments and biomolecular simulations: a perfect match? Science 361(6400):355-360.

207.

Y. Chhabra, H. Y. Wong, Louise Fletcher Nikolajsen, Helena Steinocher, A. Papadopulos, K. A. Tunny, F. A. Meunier, A. G. Smith, Birthe Brandt Kragelund, A. J. Brooks and M. J. Waters. (2018) A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation Oncogene 37:489-501.

208.

Yong Wang, Katrine Østergaard Bugge, Birthe Brandt Kragelund and Kresten Lindorff-Larsen. (2018) Role of protein dynamics in transmembrane receptor signalling Current Opinion in Structural Biology 48:74-82.

209.

Yong Wang, Omar Valsson, Pratyush Tiwary, Michele Parrinello and Kresten Lindorff-Larsen. (2018) Frequency adaptive metadynamics for the calculation of rare-event kinetics Journal of Chemical Physics 149(7):1-7.

210.

Yong Wang, Pengfei Tian, Wouter Boomsma and Kresten Lindorff-Larsen. (2018) Monte Carlo Sampling of Protein Folding by Combining an All-Atom Physics-Based Model with a Native State Bias Journal of Physical Chemistry B 122(49):11174-11185.

2017

211.

Daniel Stiefler-Jensen, Troels Schwarz-Linnet, Casper de Lichtenberg, Tam T. T. N. Nguyen, Kasper Dyrberg Rand, Li Huang, Qunxin She and Kaare Teilum. (2017) The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications Protein Science 26(9):1819-1827.

212.

Johan Gotthardt Olsen, Kaare Teilum and Birthe Brandt Kragelund. (2017) Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness Cellular and Molecular Life Sciences 74(17):3175-3183.

213.

Li He, Helena Steinocher, Ashish Shelar, Emily B. Cohen, Erin N. Heim, Birthe Brandt Kragelund, Gevorg Grigoryan and Daniel DiMaio. (2017) Single methyl groups can act as toggle switches to specify transmembrane protein-protein interactions eLife 6.

214.

Magnus Kjærgaard and Birthe Brandt Kragelund. (2017) Functions of intrinsic disorder in transmembrane proteins Cellular and Molecular Life Sciences 74(17):3205-3224.

215.

Ruth Hendus-Altenburger, Matteo Lambrughi, Thilde Bagger Terkelsen, Stine Helene Falsig Pedersen, Elena Papaleo, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2017) A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1) Cellular Signalling 37:40-51.

216.

Yong Wang, João Martins and Kresten Lindorff-Larsen. (2017) Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics Chemical Science 8(9):6466-6473.

217.

Mads Nygaard, Birthe Brandt Kragelund, Elena Papaleo and Kresten Lindorff-Larsen. (2017) An efficient method for estimating the hydrodynamic radius of disordered protein conformations Biophysical Journal 113(3):550-557.

218.

Sandra Muschiol, Simon Erlendsson, Marie-Stephanie Aschtgen, Vitor Oliveira, Peter Schmieder, Casper de Lichtenberg, Kaare Teilum, Thomas Boesen, Umit Akbey and Birgitta Henriques-Normark. (2017) Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae Journal of Biological Chemistry 292(34):14134-14146.

219.

Lasse Staby, Charlotte O'Shea, Martin Willemoës, Frederik Theisen, Birthe Brandt Kragelund and Karen Skriver. (2017) Eukaryotic transcription factors: paradigms of protein intrinsic disorder Biochemical Journal 474(15):2509-2532.

220.

Sandro Bottaro and Kresten Lindorff-Larsen. (2017) Mapping the universe of RNA tetraloop folds Biophysical Journal 113(2):257-267.

221.

Oliver Fleck, Ulrik Fahnøe, Katrine Vyff Løvschal, Marie-Fabrice Uwamahoro Gasasira, Irina Nikolaeva Marinova, Birthe Brandt Kragelund, Antony M. Carr, Edgar Hartsuiker, Christian Holmberg and Olaf Nielsen. (2017) Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication Genes 8(5).

222.

Sofie V, Nielsen, Amelie Stein, Alexander B. Dinitzen, Elena Papaleo, Michael H. Tatham, Esben Guldahl Poulsen, Maher Mahmoud Kassem, Lene Juel Rasmussen, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2017) Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations PLoS Genetics 13(4).

223.

Kaare Teilum, Micha Ben Achim Kunze, Simon Erlendsson and Birthe Brandt Kragelund. (2017) (S)Pinning down protein interactions by NMR Protein Science 26(3):436-451.

224.

Thu Phuong Tran, Christian Ørnbøl Larsen, Tobias Røndbjerg, Martina de Foresta, Micha Ben Achim Kunze, Ales Marek, Jacob Hartvig Løper, Lotte-Emilie Boyhus, Astrid Knuhtsen, Kresten Lindorff-Larsen and Daniel Sejer Pedersen. (2017) Diversity-oriented peptide stapling: a third generation copper-catalysed azide–alkyne cycloaddition stapling and functionalisation strategy Chemistry: A European Journal 23(14):3490-3495.

225.

Heike Ilona Rösner, Martina Caldarini, Andreas Prestel, Maria Antonietta Vanoni, Ricardo Americo Broglia, Alessandro Aliverti, Guido Tiana and Birthe Brandt Kragelund. (2017) Cold denaturation of the HIV-1 protease monomer Biochemistry 56(8):1029-1032.

226.

Meng S. Choy, Yang Li, Luciana E. S. F. Machado, Micha Ben Achim Kunze, Christopher R. Connors, Xingyu Wei, Kresten Lindorff-Larsen, Rebecca Page and Wolfgang Peti. (2017) Conformational rigidity and protein dynamics at distinct timescales regulate PTP1B activity and allostery Molecular Cell 65(4):644-658.

227.

Caroline Kampmeyer, Sofie V. Nielsen, Lene Clausen, Amelie Stein, Anne-Marie Axø Gerdes, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2017) Blocking protein quality control to counter hereditary cancers Genes, Chromosomes & Cancer 56(12):823-831.

228.

Charlotte O'Shea, Lasse Staby, Sidsel Krogh Bendsen, Frederik Grønbæk Tidemand, Andreas Redsted, Martin Willemoës, Birthe Brandt Kragelund and Karen Skriver. (2017) Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1 Journal of Biological Chemistry 292(2):512-527.

229.

Arun Kumar Somavarapu, Fei Shen, Kaare Teilum, Jingdong Zhang, Susanne Mossin, Peter W. Thulstrup, Morten J. Bjerrum, Manish K. Tiwari, Daniel Szunyogh, Peter M. Søtofte, Kasper P. Kepp and Lars Hemmingsen. (2017) The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+-Aß Complex Chemistry - A European Journal 23(55):13591-13595.

230.

Birthe Brandt Kragelund. (2017) Choreography by Structural Disorder in Membrane Proteins Biophysical Society. Annual Meeting. Abstracts 112:12A.

231.

Helena Steinocher, Katrine Østergaard Bugge, Louise Fletcher Nikolajsen, Kresten Lindorff-Larsen, Andrew Brooks and Birthe Brandt Kragelund. (2017) Class I Cytokine Receptors: Towards the Inside Biophysical Society. Annual Meeting. Abstracts 112:171A.

232.

Simon Erlendsson, Kamil Gotfryd, Flemming Hofmann Larsen, Jonas Sigurd Mortensen, Michel-Andreas Geiger, Barth-Jan van Rossum, Hartmut Oschkinat, Ulrik Gether, Kaare Teilum and Claus Juul Løland. (2017) Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR eLife 6.

2016

233.

Katrine Østergaard Bugge, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2016) Understanding single-pass transmembrane receptor signaling from a structural viewpoint—what are we missing? The FEBS Journal 283(24):4424-4451.

234.

Birthe Brandt Kragelund, Eric Weterings, Rasmus Hartmann-Petersen and Guido Keijzers. (2016) The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove Frontiers in Bioscience 21(3):514-527.

235.

Birthe Brandt Kragelund, Signe Marie Schenstrøm, Caio A. Rebula, Vikram Govind Panse and Rasmus Hartmann-Petersen. (2016) DSS1/Sem1, a multifunctional and intrinsically disordered protein Trends in Biochemical Sciences 41(5):446-459.

236.

Casper Højgaard, Christian Kofoed, Roall Espersen, Kristoffer Enøe Johansson, Mara Villa, Martin Willemoës, Kresten Lindorff-Larsen, Kaare Teilum and Jakob R. Winther. (2016) A soluble, folded protein without charged amino acid residues Biochemistry 55(28):3949–3956.

237.

Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans Erik Mølager Christensen, Birthe Brandt Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem and Birte Svensson. (2016) An efficient arabinoxylan-debranching a-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site Applied Microbiology and Biotechnology 100(14):6265-6277.

238.

Elena Papaleo, Giorgio Saladino, Matteo Lambrughi, Kresten Lindorff-Larsen, Francesco Luigi Gervasio and Ruth Nussinov. (2016) The role of protein loops and linkers in conformational dynamics and allostery Chemical Reviews 116(11):6391-6423.

239.

Elena Pedraz Cuesta, Jacob Fredsted, Helene H. Jensen, Annika Bornebusch, Lene N. Nejsum, Birthe Brandt Kragelund and Stine Helene Falsig Pedersen. (2016) Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells Molecular Endocrinology 30(7):693-708.

240.

Jeppe Trudslev Pedersen, Serene W. Chen, Christian Bernsen Borg, Samuel Ness, Justyna M. Bahl, Niels H. H. Heegard, Christopher M. Dobson, Lars Bo Stegeager Hemmingsen, Nunilo Cremades and Kaare Teilum. (2016) Amyloid-ß and a-synuclein decrease the level of metal-catalyzed reactive oxygen species by radical scavenging and redox silencing Journal of the American Chemical Society 138(12):3966-3969.

241.

Katrine Østergaard Bugge, Elena Papaleo, Gitte Wolfsberg Haxholm, Jonathan T.S. Hopper, Carol V. Robinson, Johan Gotthardt Olsen, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2016) A combined computational and structural model of the full-length human prolactin receptor Nature Communications 7.

242.

Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana and David E Shaw. (2016) Picosecond to Millisecond Structural Dynamics in Human Ubiquitin Journal of Physical Chemistry B 120(33):8313-8320.

243.

Kristoffer Enøe Johansson, Nicolai Tidemand Johansen, Signe Christensen, Scott Horowitz, James C. A. Bardwell, Johan Gotthardt Olsen, Martin Willemoës, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck and Jakob R. Winther. (2016) Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template Journal of Molecular Biology 428(21):4361-4377.

244.

Maher Mahmoud Kassem, Yong Wang, Wouter Krogh Boomsma and Kresten Lindorff-Larsen. (2016) Structure of the bacterial cytoskeleton protein bactofilin by NMR chemical shifts and sequence variation Biophysical Journal 110(11):2342-2348.

245.

Matteo Lambrughi, Luca De Gioia, Francesco Luigi Gervasio, Kresten Lindorff-Larsen, Ruth Nussinov, Chiara Urani, Maurizio Bruschi and Elena Papaleo. (2016) DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions Nucleic Acids Research 44(19):9096-9109.

246.

Nicholas Peter Schafer, Ha H. Truong, Daniel E. Otzen, Kresten Lindorff-Larsen and Peter G. Wolynes. (2016) Topological constraints and modular structure in the folding and functional motions of GlpG, an intramembrane protease Proceedings of the National Academy of Sciences of the United States of America 113(8):2098-2103.

247.

Pengfei Tian, Kresten Lindorff-Larsen, Wouter Krogh Boomsma, Mogens Hogh Jensen and Daniel Erik Otzen. (2016) A Monte Carlo study of the early steps of functional amyloid formation P L o S One 11(1).

248.

Richard T. Timms, Sam A. Menzies, Iva A. Tchasovnikarova, Lea Cecilie Christensen, James C. Williamson, Robin Antrobus, Gordon Dougan, Lars Ellgaard and Paul J. Lehner. (2016) Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens Nature Communications 7.

249.

Ruth Hendus-Altenburger, Elena Pedraz Cuesta, Christina Wilkens Olesen, Elena Papaleo, Jeff Alexander Schnell, Jonathan T. S. Hopper, Carol V. Robinson, Stine Helene Falsig Pedersen and Birthe Brandt Kragelund. (2016) The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2 BMC Biology 14.

250.

Troels Schwarz-Linnet and Kaare Teilum. (2016) Non-uniform sampling of NMR relaxation data Journal of Biomolecular N M R 64(2):165-173.

251.

Wouter Krogh Boomsma, Sofie Vincents Nielsen, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen and Lars Ellgaard. (2016) Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases PeerJ 4.

252.

Yong Wang, Elena Papaleo and Kresten Lindorff-Larsen. (2016) Mapping transiently formed and sparsely populated conformations on a complex energy landscape eLife 5.

2015

253.

Morten L. Karlsen, Thor S. Thorsen, Niklaus Johner, Ina Ammendrup-Johnsen, Simon Erlendsson, Xinsheng Tian, Jens B. Simonsen, Rasmus Hoiberg-Nielsen, Nikolaj M. Christensen, George Khelashvili, Werner Streicher, Kaare Teilum, Bente Vestergaard, Harel Weinstein, Ulrik Gether, Lise Arleth and Kenneth L. Madsen. (2015) Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering Structure 23(7):1258-1270.

254.

Charlotte O'Shea, Mikael Kryger Jensen, Emil G.P. Stender, Birthe Brandt Kragelund, Martin Willemoës and Karen Skriver. (2015) Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1 Biochemical Journal 465(2):281-294.

255.

Chi Zhang, Ibtissem Cherifi, Mads Nygaard, Gitte Wolfsberg Haxholm, Roman L. Bogorad, Marie Bernadet, Patrick England, Isabelle Broutin, Birthe Brandt Kragelund, Jacques-Emmanuel Guidotti and Vincent Goffin. (2015) Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis Molecular and Cellular Endocrinology 401:173-188.

256.

Chi Zhang, Mads Nygaard, Gitte Wolfsberg Haxholm, Florence Boutillon, Marie Bernadet, Sylviane Hoos, Patrick England, Isabelle Broutin, Birthe Brandt Kragelund and Vincent Goffin. (2015) A residue quartet in the extracellular domain of the prolactin receptor selectively controls mitogen-activated protein kinase signaling Journal of Biological Chemistry 290(19):11890-11904.

257.

Fernando Martin-García, Elena Papaleo, Paulino Gomez-Puertas, Wouter Krogh Boomsma and Kresten Lindorff-Larsen. (2015) Comparing molecular dynamics force fields in the essential subspace PLoS ONE 10(3).

258.

Gitte Wolfsberg Haxholm, Louise Fletcher Nikolajsen, Johan Gotthardt Olsen, Jacob Fredsted, Flemming Hofmann Larsen, Vincent Goffin, Stine Helene Falsig Pedersen, Andrew J Brooks, Michael J Waters and Birthe Brandt Kragelund. (2015) Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes Biochemical Journal 468(3):495-506.

259.

Irina Nikolaeva Marinova, Jacob Engelbrecht, Adrian Ewald, Lasse L. Langholm, Christian Henrik Holmberg, Birthe Brandt Kragelund, Colin Gordon, Olaf Nielsen and Rasmus Hartmann-Petersen. (2015) Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing P L o S One 10(2).

260.

Jeppe Trudslev Pedersen, Christian Bernsen Borg, Thomas C. T. Michaels, Tuomas P. J. Knowles, Peter Faller, Kaare Teilum and Lars Bo Stegeager Hemmingsen. (2015) Aggregation prone amyloid-߷CuII Species formed on the millisecond timescale at mildly acidic conditions ChemBioChem 16(9):1293-1297.

261.

Kaare Teilum, Johan Gotthardt Olsen and Birthe Brandt Kragelund. (2015) Globular and disordered-the non-identical twins in protein-protein interactions Frontiers in Bioscience 2.

262.

Katrine Østergaard Bugge, Helena Steinocher, Andrew J. Brooks, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2015) Exploiting hydrophobicity for efficient production of transmembrane helices for structure determination by NMR spectroscopy Analytical Chemistry 87(18):9126–9131.

263.

Leila Malik, Jesper Nygård, Niels Johan Christensen, Charlotte Stahl Madsen, Heike Ilona Rösner, Birthe Brandt Kragelund, Rasmus Høiberg-Nielsen, Werner Streicher, Lise Arleth, Peter Waaben Thulstrup and Knud Jørgen Jensen. (2015) A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template ChemBioChem 16(13):1905-1918.

264.

Lorenzo Sborgi, Abhinav Verma, Stefano Piana, Kresten Lindorff-Larsen, Michele Cerminara, Clara M. Santiveri, David E. Shaw, Eva De Alba and Victor Muñoz. (2015) Interaction networks in protein folding via atomic-resolution experiments and long-time-scale molecular dynamics simulations Journal of the American Chemical Society 137(20):6506-6516.

265.

Matteo Tiberti, Elena Papaleo, Tone Bengtsen, Wouter Krogh Boomsma and Kresten Lindorff-Larsen. (2015) ENCORE: Software for Quantitative Ensemble Comparison PLoS Computational Biology 11(10).

266.

Mohsin M Naqvi, Pétur Orri Heiðarsson, Mariela R Otazo, Alessandro Mossa, Birthe Brandt Kragelund and Ciro Cecconi. (2015) Single-molecule folding mechanisms of the apo- and Mg2+-bound states of human neuronal calcium sensor-1 Biophysical Journal 109(1):113-123.

267.

Pengfei Tian, Wouter Krogh Boomsma, Yong Wang, Daniel Erik Otzen, Mogens Høgh Jensen and Kresten Lindorff-Larsen. (2015) What does evolution tell us about the structure of a functional amyloid protein? Biophysical Journal 108:227a.

268.

Pengfei Tian, Wouter Krogh Boomsma, Yong Wang, Daniel Otzen, Mogens Høgh Jensen and Kresten Lindorff-Larsen. (2015) Structure of a functional amyloid protein subunit computed using sequence variation Journal of the American Chemical Society 137(1):22–25.

269.

Søs Grønbæk Mathiassen, Ida B. Larsen, Esben Guldahl Poulsen, Christian Toft Madsen, Elena Papaleo, Kresten Lindorff-Larsen, Birthe Brandt Kragelund, Michael Lund Nielsen, Franziska Kriegenburg and Rasmus Hartmann-Petersen. (2015) A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast The Journal of Biological Chemistry 290(34):21141-21153.

270.

Yang Guo, Birthe Brandt Kragelund, Malcolm F. White and Xu Peng. (2015) Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities Journal of Molecular Biology 427(12):2179-2191.

2014

271.

Elena Papaleo, Ludovico Sutto, Francesco Luigi Gervasio and Kresten Lindorff-Larsen. (2014) Conformational changes and free energies in a Proline isomerase Journal of Chemical Theory and Computation 10(9):4169-4174.

272.

Gaetano Invernizzi, Matteo Tiberti, Matteo Lambrughi, Kresten Lindorff-Larsen and Elena Papaleo. (2014) Communication routes in ARID domains between distal residues in Helix 5 and the DNA-binding loops P L o S Computational Biology (Online) 10(9).

273.

Jacob Andersen-Usaj, Amalie C. Bonde, Jessica Pihl, Marie-Louise F. Thomsen, Miki Shavit, Jeppe Trudslev Pedersen, Kaare Teilum, Peter Waaben Thulstrup and Lars Bo Stegeager Hemmingsen. (2014) Binding of Cu2+ to the islet amyloid polypeptide (IAPP) Journal of Biological Inorganic Chemistry 19:S812.

274.

Jeppe Trudslev Pedersen, Christian B. Borg, Kaare Teilum and Lars Bo Stegeager Hemmingsen. (2014) pH dependence of amyloid-ß-Cu(II) binding and oligomerization kinetics Journal of Biological Inorganic Chemistry 19:S755.

275.

Johan Gotthardt Olsen and Birthe Brandt Kragelund. (2014) Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats Cytokine & Growth Factor Reviews 25(3):337-341.

276.

Konstantinos Paraskevopoulos, Franziska Kriegenburg, Michael H. Tatham, Heike Ilona Rösner, Bethan Medina, Ida B. Larsen, Rikke Brandstrup, Kevin G. Hardwick, Ronald T. Hay, Birthe Brandt Kragelund, Rasmus Hartmann-Petersen and Colin Gordon. (2014) Dss1 is a 26S proteasome ubiquitin receptor Molecular Cell 56(3):453-461.

277.

Kristine Steen Jensen, Jeppe Trudslev Pedersen, Jakob R. Winther and Kaare Teilum. (2014) The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin Biochemistry 53(15):2533-2540.

278.

Miki Shavit, Amalie Carnbring Bonde, Jessica Pihl, Marie-Louise F Thomsen, Jeppe Trudslev Pedersen, Jacob Andersen-Usaj, Kaare Teilum, Lars Bo Stegeager Hemmingsen and Peter Waaben Thulstrup. (2014) Islet amyloid polypeptide (IAPP)-Structural effects of Zn2+ Journal of Biological Inorganic Chemistry 19:S813.

279.

Pengfei Tian, Sigurður Ægir Jónsson, Jesper Ferkinghoff-Borg, Sergei V . Krivov, Kresten Lindorff-Larsen, Anders Irbäck and Wouter Krogh Boomsma. (2014) Robust estimation of diffusion-optimized ensembles for enhanced sampling Journal of Chemical Theory and Computation 10(2):543–553.

280.

Pétur Orri Heiðarsson, Mohsin M. Naqvi, Mariela R. Otazo, Alessandro Mossa, Birthe Brandt Kragelund and Ciro Cecconi. (2014) Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1 Proceedings of the National Academy of Sciences U.S.A. 111(36):13069-13074.

281.

Rasmus Vejrup-Hansen, Oliver Fleck, Katrine Landvad, Ulrik Fahnøe, Sebastian S. Broendum, Ann-Sofie Schreurs, Birthe Brandt Kragelund, Antony M. Carr, Christian Henrik Holmberg and Olaf Nielsen. (2014) Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools Journal of Cell Science 127:2460-2470.

282.

Ruth Hendus-Altenburger, Birthe Brandt Kragelund and Stine Helene Falsig Pedersen. (2014) Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers Current Topics in Membranes - Exchangers 73:69-148.

283.

Sebastien Morin, Troels Emtekær Linnet, Mathilde Lescanne, Paul Schanda, Gary S. Thompson, Martin Tollinger, Kaare Teilum, Stephane Gagne, Dominique Marion, Christian Griesinger, Martin Blackledge and Edward J. d’Auvergne. (2014) relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data Bioinformatics 30(15):2219-2220.

284.

Simon Erlendsson, Mette Rathje, Pétur Orri Heiðarsson, Flemming Martin Poulsen, Kenneth Lindegaard Madsen, Kaare Teilum and Ulrik Gether. (2014) Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/Discs-Large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands Journal of Biological Chemistry 289(36):25327-25340.

285.

Simon Olsson, Beat Rolf Vögeli, Andrea Cavalli, Wouter Krogh Boomsma, Jesper Ferkinghoff-Borg, Kresten Lindorff-Larsen and Thomas Wim Hamelryck. (2014) Probabilistic determination of native state ensembles of proteins Journal of Chemical Theory and Computation 10(8):3484-3491.

286.

Ulrich Weininger, Ulrika Brath, Kristofer Modig, Kaare Teilum and Mikael Akke. (2014) Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection Journal of Biomolecular NMR 59(1):23-29.

287.

Valéry Ozenne, Jeffrey K. Noel, Pétur Orri Heiðarsson, Søren Brander, Flemming Martin Poulsen, Malene Ringkjøbing Jensen, Birthe Brandt Kragelund, Martin Blackledge and Jens Albert Danielsson. (2014) Exploring the minimally frustrated energy landscape of unfolded ACBP Journal of Molecular Biology 426(3):722-734.

288.

Vytautas Iesmantavicius, Jakob Dogan, Per Jemth, Kaare Teilum and Magnus Kjærgaard. (2014) Helical propensity in an intrinsically disordered protein accelerates ligand binding Angewandte Chemie (International ed. in English) 53(6):1548-1551.

289.

Wouter Krogh Boomsma, Jesper Ferkinghoff-Borg and Kresten Lindorff-Larsen. (2014) Combining experiments and simulations using the maximum entropy principle PLoS Computational Biology 10(2).

290.

Wouter Krogh Boomsma, Pengfei Tian, Jes Frellsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck, Kresten Lindorff-Larsen and Michele Vendruscolo. (2014) Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts Proceedings of the National Academy of Sciences of the United States of America 111(38):13852-13857.

2013

291.

Anders Steen Christensen, Troels Emtekær Linnet, Mikael Borg, Wouter Krogh Boomsma, Kresten Lindorff-Larsen, Thomas Wim Hamelryck and Jan Halborg Jensen. (2013) Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics PLoS ONE 8(12).

292.

Anders Steen Christensen, Troels Emtekær Linnet, Mikael Borg, Wouter Krogh Boomsma, Kresten Lindorff-Larsen, Thomas Wim Hamelryck and Jan Halborg Jensen. (2013) Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics PLoS ONE 8(12).

293.

Anders Steen Christensen, Troels Emtekær Linnet, Mikael Borg, Wouter Krogh Boomsma, Kresten Lindorff-Larsen, Thomas Wim Hamelryck and Jan Halborg Jensen. (2013) Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics PLoS ONE 8(12).

294.

Chandra Kenchappa, Pétur Orri Heiðarsson, Birthe Kragelund, Roger Garrett and Flemming Poulsen. (2013) Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2 Nucleic Acids Research 41(5):3424-3435.

295.

Jens Munk, Lea Thøgersen, Lars Erik Uggerhøj, Reinhard Wimmer, Niels Frimodt-Møller, Kresten Lindorff-Larsen and Paul Robert Hansen. (2013) The Structure of the Central Side Chain is Crucial for Anoplin Hemolytic Activity Proceedings of the 23rd American Peptide Symposium.

296.

Lea Ellegaard-Jensen, Jens Aamand, Birthe Brandt Kragelund, A.H. Johnsen and Søren Rosendahl. (2013) Strains of the soil fungus Mortierella show different degradation potentials for the phenylurea herbicide diuron Biodegradation 24(6):765-774.

297.

Magnus Kjaergaard, Lisbeth Andersen, Lau Dalby Nielsen and Kaare Teilum. (2013) A Folded Excited State of Ligand-Free Nuclear Coactivator Binding Domain (NCBD) Underlies Plasticity in Ligand Recognition. Biochemistry 52(10):1686-1693.

298.

Olav M. Andersen, Robert Dagil and Birthe Brandt Kragelund. (2013) New horizons for lipoprotein receptors: communication by ß-propellers Journal of Lipid Research 54:2763-2774.

299.

Pétur Orri Heiðarsson, Mariela R. Otazo, Luca Bellucci, Alessandro Mossa, Alberto Imparato, Emanuele Paci, Stefano Corni, Rosa Di Felice, Birthe Brandt Kragelund and Ciro Cecconi. (2013) Single-molecule folding mechanism of an EF-hand neuronal calcium sensor Structure 21(10):1812-1821.

300.

Predrag Kukic, Damien Farrell, Lawrence P. McIntosh, Bertrand García-Moreno E., Kristine Steen Jensen, Zigmantas Toleikis, Kaare Teilum and Jens Erik Nielsen. (2013) Protein dielectric constants determined from NMR chemical shift perturbations Journal of the American Chemical Society 135(45):16968–16976.

301.

Robert Dagil, Charlotte O'Shea, Anders Nykjær, Alexandre M J J Bonvin and Birthe B Kragelund. (2013) Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin The Journal of Biological Chemistry 288(6):4424-35.

302.

Robert Tsanev, Kalju Vanatalu, Jüri Jarvet, Risto Tanner, Kristi Laur, Piret Tiigimägi, Birthe Brandt Kragelund, Torben Østerlund and Priit Kogerman. (2013) The transcriptional repressor domain of Gli3 is intrinsically disordered PLoS ONE 8(10).

303.

Sandro Bottaro, Kresten Lindorff-Larsen and Robert B. Best. (2013) Variational optimization of an all-atom implicit solvent force field to match explicit solvent simulation data Journal of Chemical Theory and Computation 9(12):5641-5652.

304.

Stefano Piana, Kresten Lindorff-Larsen and David E. Shaw. (2013) Atomic-level description of ubiquitin folding Proceedings of the National Academy of Sciences of the United States of America 110(15):5915-5920.

305.

Stefano Piana, Kresten Lindorff-Larsen and David E. Shaw. (2013) Atomistic description of the folding of a dimeric protein Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical 117(42):12935-12942.

306.

Wouter Krogh Boomsma, Jes Frellsen, Tim Philipp Harder, Sandro Bottaro, Kristoffer Enøe Johansson, Pengfei Tian, Kasper Stovgaard, Christian Andreetta, Simon Olsson, Jan Valentin, Lubomir Dimitrov Antonov, Anders Steen Christensen, Mikael Borg, Jan Halborg Jensen, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg and Thomas Wim Hamelryck. (2013) PHAISTOS: a framework for Markov chain Monte Carlo simulation and inference of protein structure Journal of Computational Chemistry 34(19):1697-1705.

2012

307.

Anneli Edström Hägerwall, Victoria Rydengård, Per Fernlund, Matthias Mörgelin, Maria Baumgarten, Alexander M. Cole, Martin Malmsten, Birthe Kragelund and Ole E. Sørensen. (2012) ß-Microseminoprotein endows post coital seminal plasma with potent candidacidal activity by a calcium- and pH-dependent mechanism. P L o S Pathogens 8(4):1-12.

308.

Birthe Brandt Kragelund, Michael Krogh Jensen and Karen Skriver. (2012) Order by disorder in plant signaling Trends in Plant Science 17(11):625-632.

309.

Elena Papaleo, Kresten Lindorff-Larsen and Luca De Gioia. (2012) Paths of long-range communication in the E2 enzymes of family 3: a molecular dynamics investigation Physical Chemistry Chemical Physics 14:12515-12525.

310.

Esben G Poulsen, Cornelia Steinhauer, Michael Lees, Anne-Marie Lauridsen, Lars Ellgaard and Rasmus Hartmann-Petersen. (2012) HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin P L o S One 7(11).

311.

Heike Rösner and Birthe Kragelund. (2012) Structure and Dynamic Properties of Membrane Proteins using NMR Comprehensive Physiology 2(2):1491-1539.

312.

Kresten Lindorff-Larsen, Nikola Trbovic, Paul Maragakis, Stefano Piana and David E Shaw. (2012) Structure and dynamics of an unfolded protein examined by molecular dynamics simulation Journal of the American Chemical Society 134(8):3787-3791.

313.

Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana, Michael P Eastwood, Ron O Dror and David E Shaw. (2012) Systematic validation of protein force fields against experimental data P L o S One 7(2).

314.

Lea Cecilie Christensen, Njal Winther Jensen, Andrea Lages Lino Vala, Jurate Kamarauskaite, Linda Christina Johansson, Jakob R. Winther, Kay Hofmann, Kaare Teilum and Lars Ellgaard. (2012) The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region Journal of Biological Chemistry 287(31):26388-26399.

315.

Magnus Kjærgaard, Flemming Martin Poulsen and Birthe Brandt Kragelund. (2012) Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses Intrinsically disordered protein analysis - methods and experimental tools 2:249-256.

316.

Magnus Kjærgaard, Flemming Martin Poulsen and Birthe Brandt Kragelund. (2012) Temperature-induced transitions in disordered proteins probed by NMR spectroscopy Intrinsically disordered protein analysis - methods and experimental tools 2:233-247.

317.

Magnus Kjærgaard, Flemming Martin Poulsen and Kaare Teilum. (2012) Is a malleable protein necessarily highly dynamic?: The hydrophobic core of the nuclear coactivator binding domain is well ordered Biophysical Journal 102(7):1627-1635.

318.

Pétur Orri Heiðarsson, Ida Jannike Bjerrum-Bohr, Gitte A. Jensen, Olaf Pongs, Bryan E. Finn, Flemming Martin Poulsen and Birthe Brandt Kragelund. (2012) The C-terminal tail of human neuronal calcium sensor 1 regulates the conformational stability of the Ca2+-activated state Journal of Molecular Biology 417:51-64.

319.

Pétur Orri Heiðarsson, Immanuel Valpapuram, Carlo Camilloni, Alberto Imparato, Guido Tiana, Flemming Martin Poulsen, Birthe Brandt Kragelund and Ciro Cecconi. (2012) A highly compliant protein native state with a spontaneous-like mechanical unfolding pathway Journal of the American Chemical Society 134(41):17068-17075.

320.

Robert Dagil, Maiken J. Knudsen, Johan Gotthardt Olsen, Charlotte O'Shea, Magnus Franzmann, Vincent Goffin, Kaare Teilum, Jens Breinholt and Birthe Brandt Kragelund. (2012) The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor Structure 20(2):270-282.

321.

Stefano Piana, Kresten Lindorff-Larsen and David E. Shaw. (2012) Protein folding kinetics and thermodynamics from atomistic simulation Proceedings of the National Academy of Sciences of the United States of America 109(44):17845-17850.

322.

Stefano Piana, Kresten Lindorff-Larsen, Robert M Dirks, John K Salmon, Ron O Dror and David E Shaw. (2012) Evaluating the effects of cutoffs and treatment of long-range electrostatics in protein folding simulations P L o S One 7(6).

2011

323.

Stefano Piana, Krishnarjun Sarkar, Kresten Lindorff-Larsen, Minghao Guo, Martin Gruebele and David E Shaw. (2011) Computational design and experimental testing of the fastest-folding ß-sheet protein Journal of Molecular Biology 405(1):43-48.

324.

Ann-Beth Nørholm, Ruth Hendus-Altenburger, Gabriel Bjerre, Magnus Kjærgaard, Stine Helene Falsig Pedersen and Birthe B Kragelund. (2011) The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking Biochemistry 50(17):3469-80.

325.

Helen Webb, Barbara Mary Tynan-Connolly, Gregory M Lee, Damien Farrell, Fergal O'Meara, Chresten R Søndergaard, Kaare Teilum, Chandralal Hewage, Lawrence P McIntosh and Jens Erik Nielsen. (2011) Remeasuring HEWL pKa values by NMR spectroscopy : methods, analysis, accuracy, and implications for theoretical pKa calculations Proteins: Structure, Function, and Bioinformatics 79(3):685-702.

326.

Jeppe Trudslev Pedersen, Kaare Teilum, Niels H. H. Heegaard, Jesper Østergaard, Hans-Werner Adolph and Lars Bo Stegeager Hemmingsen. (2011) Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid ß peptides Angewandte Chemie International Edition 50(11):2532-2535.

327.

Kaare Teilum, Johan G Olsen and Birthe B Kragelund. (2011) Protein stability, flexibility and function B B A - Proteins and Proteomics 1814(8):969-76.

328.

Kresten Lindorff-Larsen, Stefano Piana, Ron O Dror and David E Shaw. (2011) How fast-folding proteins fold Science (New York, N.Y.) 334(6055):517-20.

329.

Kristine Steen Jensen, Jakob R Winther and Kaare Teilum. (2011) Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states Journal of the American Chemical Society 133(9):3034-42.

330.

Louise Meinert Niclasen, Johan G Olsen, Robert Dagil, Zhang Qing, Ole E Sørensen and Birthe B Kragelund. (2011) Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin Biochemical Journal 434(1):123-32.

331.

Mathilde Johanne Kaas Hansen, Johan Gotthardt Olsen, Sophie Bernichtein, Charlotte O'Shea, Bent Walther Sigurskjold, Vincent Goffin and Birthe Brandt Kragelund. (2011) Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding. Journal of Molecular Recognition 24(4):533-547.

332.

Stefano Piana, Kresten Lindorff-Larsen and David E Shaw. (2011) How robust are protein folding simulations with respect to force field parameterization? Biophysical Journal (2011) 100(9):L47-L49.

333.

Trine Kjaersgaard, Michael K Jensen, Michael W Christiansen, Per L. Gregersen, Birthe B Kragelund and Karen Skriver. (2011) Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain Journal of Biological Chemistry 286(41):35418-29.

2010

334.

Magnus Kjærgaard, Ann-Beth Nørholm, Ruth Hendus-Altenburger, Stine Helene Falsig Pedersen, Flemming M Poulsen and Birthe B Kragelund. (2010) Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II? Protein Science 19(8):1555-64.

335.

Konstantinos Nestoras, Asma Hadi Mohammed, Ann-Sofie Schreurs, Oliver Fleck, Adam T Watson, Marius Poitelea, Charlotte O'Shea, Charly Chahwan, Christian Holmberg, Birthe B Kragelund, Olaf Nielsen, Mark Osborne, Antony M Carr and Cong Liu. (2010) Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms Genes & Development 24(11):1145-1159.

336.

Kresten Lindorff-Larsen, Stefano Piana, Kim Palmo, Paul Maragakis, John L Klepeis, Ron O Dror and David E Shaw. (2010) Improved side-chain torsion potentials for the Amber ff99SB protein force field Proteins: Structure, Function, and Bioinformatics 78(8):1950-8.

337.

David E Shaw, Paul Maragakis, Kresten Lindorff-Larsen, Stefano Piana, Ron O Dror, Michael P Eastwood, Joseph A Bank, John M Jumper, John K Salmon, Yibing Shan and Willy Wriggers. (2010) Atomic-level characterization of the structural dynamics of proteins Science (New York, N.Y.) 330(6002):341-6.

338.

Isabelle Broutin, Jean-Baptiste Jomain, Estelle Tallet, Jan Van Agthoven, Bertand Raynal, Sylviane Hoos, Birthe Brandt Kragelund, Paul Kelly, Alexandre Ducroix, Patrick England and Vincent Goffin. (2010) Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2. Journal of Biological Chemistry 285(11):8422-8433.

339.

Magnus Kjærgaard, Kaare Teilum and Flemming M Poulsen. (2010) Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP Proceedings of the National Academy of Science of the United States of America 107(28):12535-40.

340.

Morten ؠJensen, David W Borhani, Kresten Lindorff-Larsen, Paul Maragakis, Vishwanath Jogini, Michael P Eastwood, Ron O Dror and David E Shaw. (2010) Principles of conduction and hydrophobic gating in K+ channels Proceedings of the National Academy of Sciences of the United States of America 107(13):5833-8.

2009

341.

Willy Wriggers, Kate A. Stafford, Yibing Shan, Stefano Piana, Paul Maragakis, Kresten Lindorff-Larsen, Patrick J. Miller, Justin Gullingsrud, Charles A. Rendleman, Michael P. Eastwood, Ron O. Dror and David E. Shaw. (2009) Automated Event Detection and Activity Monitoring in Long Molecular Dynamics Simulations Journal of Chemical Theory and Computation 5(10):2595-2605.

342.

David E. Shaw, Ron O. Dror, John K. Salmon, J. P. Grossman, Kenneth M. Mackenzie, Joseph A. Bank, Cliff Young, Martin M. Deneroff, Brannon Batson, Kevin J. Bowers, Edmond Chow, Michael P. Eastwood, Doug Ierardi, John L. Klepeis, Jeffrey Kuskin, Richard H. Larson, Kresten Lindorff-Larsen, Paul Maragakis, Mark A. Moraes, Stefano Piana, Yibing Shan and Brian Towles. (2009) Millisecond-scale molecular dynamics simulations on Anton Proceedings of the Conference on High Performance Computing Networking, Storage and Analysis.

343.

Johan G Olsen, Robert Dagil, Louise Meinert Niclasen, Ole E Sørensen and Birthe B Kragelund. (2009) Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form Journal of Molecular Biology 393(3):693-703.

344.

John L Klepeis, Kresten Lindorff-Larsen, Ron O Dror and David E Shaw. (2009) Long-timescale molecular dynamics simulations of protein structure and function Current Opinion in Structural Biology 19(2):120-7.

345.

Kaare Teilum, Johan G Olsen and Birthe B Kragelund. (2009) Functional aspects of protein flexibility Cellular and Molecular Life Sciences 66(14):2231-47.

346.

Kaare Teilum, Melanie H Smith, Eike Schulz, Lea C Christensen, Gleb Solomentsev, Mikael Oliveberg and Mikael Akke. (2009) Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization Proceedings of the National Academy of Science of the United States of America 106(43):18273-8.

347.

Kresten Lindorff-Larsen and Jesper Ferkinghoff-Borg. (2009) Similarity measures for protein ensembles PLoS ONE 4(1).

348.

Nora Badawi, Stig Rønhede, Stefan Olsson, Birthe Brandt Kragelund, Anders Holten Johnsen, Ole Stig Jacobsen and Jens Aamand. (2009) Metabolites of the phenylurea herbicides chlorotoluron, diuron, isoproturonand linuron produced by the soil fungus Mortierella sp. Environmental Pollution 157(10):2806-2812.

2008

349.

Anders B. Nørgaard, Jesper Ferkinghoff-Borg and Kresten Lindorff-Larsen. (2008) Experimental parameterization of an energy function for the simulation of unfolded proteins Biophysical Journal 94(1):182-192.

350.

Jais R Bjelke, Ole H Olsen, Michel Fodje, L Anders Svensson, Susanne Bang, Gert Bolt, Birthe B Kragelund and Egon Persson. (2008) Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity Journal of Biological Chemistry 283(38):25863-70.

351.

Jens Danielsson, Leena Liljedahl, Elsa Ba´ra´ny-Wallje, Pernille Sønderby, Line Hyltoft Kristensen, Maria A Martinez-Yamout, H Jane Dyson, Peter E Wright, Flemming M Poulsen, Lena Ma¨ler, Astrid Gra¨slund and Birthe B Kragelund. (2008) The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer Biochemistry 47(50):13428-13437.

352.

Jesper S Hansen, Nils J Færgeman, Birthe B Kragelund and Jens Knudsen. (2008) Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells. Biochemical Journal 410(3):463-472.

353.

Line Hyltoft Kristensen, Peter E. Nielsen, Christian Isak Jørgensen, Birthe B Kragelund and Niels Erik Møllegaard. (2008) Phosphate Selective Uranyl Photo-Affinity Cleavage of Proteins. Determination of Phosphorylation Sites. ChemBioChem 9(15):2377-81.

354.

Paul Maragakis, Kresten Lindorff-Larsen, Michael P Eastwood, Ron O Dror, John L Klepeis, Isaiah T Arkin, Morten ؠJensen, Huafeng Xu, Nikola Trbovic, Richard A Friesner, Arthur G Palmer Iii and David E Shaw. (2008) Microsecond molecular dynamics simulation shows effect of slow loop dynamics on backbone amide order parameters of proteins Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical 112(19):6155-6158.

2007

355.

Caspar Elo Christensen, Birthe Brandt Kragelund, Penny Von Wettstein-Knowles and Anette Henriksen. (2007) Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase Protein Science 16(2):261-272.

356.

Christian D Geierhaas, Adrian A Nickson, Kresten Lindorff-Larsen, Jane Clarke and Michele Vendruscolo. (2007) BPPred: a Web-based computational tool for predicting biophysical parameters of proteins Protein Science 16(1):125-34.

357.

Jean-Baptiste Jomain, Estelle Tallet, Isabelle Broutin, Sylviane Hoos, Jan van Agthoven, Arnaud Ducruix, Paul A Kelly, Birthe B Kragelund, Patrick England and Vincent Goffin. (2007) Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL. Journal of Biological Chemistry 282(45):33118-31.

358.

Katrine S Larsen, Henrik Østergaard, Jais R Bjelke, Ole H Olsen, Hanne B Rasmussen, Leif Christensen, Birthe B Kragelund and Henning R Stennicke. (2007) Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa. Biochemical Journal 405(3):429-38.

359.

Kristofer Modig, Vibeke W. Jürgensen, Kresten Lindorff-Larsen, Wolfgang Fieber, Henrik G Bohr and Flemming Martin Poulsen. (2007) Detection of initiation sites in protein folding of the four helix bundle ACBP by chemical shift analysis. FEBS Letters 581(25):4965-4971.

360.

Nils J Faergeman, Majken Wadum, Søren Feddersen, Mark Burton, Birthe B Kragelund and Jens Knudsen. (2007) Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA. Molecular and Cellular Biochemistry 299:55-65.

361.

Patrik Lundström, Kaare Teilum, Tommy Carstensen, Irina Bezsonova, Silke Wiesner, D Flemming Hansen, Tomasz L Religa, Mikael Akke and Lewis E Kay. (2007) Fractional 13C enrichment of isolated carbons using [1-13C]- or [2- 13C]-glucose facilitates the accurate measurement of dynamics at backbone Calpha and side-chain methyl positions in proteins Journal of Biomolecular NMR 38(3):199-212.

362.

Sandra Lerche Søndergaard, Niels Frimodt-Møller, Birthe Brandt Kragelund and Paul Robert Hansen. (2007) Structure-activity study of the antibacterial peptide fallaxin Protein Science 16(9):1969-1976.

2006

363.

C. J. Francis, Kresten Lindorff-Larsen, R. B. Best and M. Bendruscolo. (2006) Characterization of the residual structure in the unfolded state of the Delta 131 Delta fragment of staphylococcal nuclease Proteins - Structure Function and Bioinformatics 65(1):145-52.

364.

Gitte A Jensen, Olav M Andersen, Alexandre M J J Bonvin, Ida Bjerrum-Bohr, Michael Etzerodt, Hans C Thøgersen, Charlotte O'Shea, Flemming M Poulsen and Birthe B Kragelund. (2006) Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif. Journal of Molecular Biology 362(4):700-16.

365.

Houman Ghasriani, Kaare Teilum, Ylva Johnsson, Per Fernlund and Torbjörn Drakenberg. (2006) Solution structures of human and porcine beta-microseminoprotein Journal of Molecular Biology 362(3):502-15.

366.

Jais R Bjelke, Egon Persson, Hanne B Rasmussen, Birthe B Kragelund and Ole H Olsen. (2006) A loop of coagulation factor VIIa influencing macromolecular substrate specificity. FEBS Letters 581(1):71-6.

367.

Kaare Teilum, F. M. Poulsen and M. Akke. (2006) The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein. Proceedings of the National Academy of Science of the United States of America 103(18):6867-6882.

368.

Kaare Teilum, Flemming M Poulsen and Mikael Akke. (2006) The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein Proceedings of the National Academy of Science of the United States of America 103(18):6877-82.

369.

Kaare Teilum, Ulrika Brath, Patrik Lundström and Mikael Akke. (2006) Biosynthetic 13C labeling of aromatic side chains in proteins for NMR relaxation measurements Journal of the American Chemical Society 128(8):2506-7.

370.

M. Louhivuori, R. Otten, Kresten Lindorff-Larsen and A. Annila. (2006) Conformational fluctuations affect protein alignment in dilute liquid crystal media. Journal of the American Chemical Society 128(13):4371-4376.

371.

R. B. Best, Kresten Lindorff-Larsen, M. A. DePristo and M. VEndruscolo. (2006) Relation between native ensembles and experimental structures of proteins. Proceedings of the National Academy of Science of the United States of America 103(29):10901-6.

372.

Vidya Chandran, Elliott J Stollar, Kresten Lindorff-Larsen, Jeffrey F Harper, Walter J Chazin, Christopher M Dobson, Ben F Luisi and John Christodoulou. (2006) Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition Journal of Molecular Biology 357(2):400-10.

2005

373.

Emanuele Paci, K. Lindorff-Larsen, Christopher M. Dobson, Martin Karplus and Michele Vendruscolo. (2005) Transition State Contact Orders Correlate with Protein Folding Rates Journal of Molecular Biology 352(3):495-500.

374.

Kaare Teilum, Birthe Brandt Kragelund and Flemming Martin Poulsen. (2005) Application of Hydrogen Exchange Kinetics to Studies of Protein Folding Protein Folding Handbook:634-672.

375.

Kaare Teilum, Jeffrey C Hoch, Vincent Goffin, Sandrina Kinet, Joseph A Martial and Birthe B Kragelund. (2005) Solution structure of human prolactin Journal of Molecular Biology 351(4):810-23.

376.

Kaare Teilum, Thorsten Thormann, Nigel R. Caterer, Heidi I. Poulsen, Peter H. Jensen, Jens Knudsen, Birthe Brandt Kragelund and Flemming M. Poulsen. (2005) Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles Proteins - Structure Function and Bioinformatics 59(1):80-90.

377.

Karen L. Maxwell, D. Wildes, A. Zarrine-Afsar, Miguel A. De Los Rios Rivos, Andrew G. Brown, Claire T. Friel, Linda Hedberg, Jia-Cherng Horng, Diana Bona, Erik J. Miller, Alexis Vallée-Bélisle, Ewan R. G. Main, Francesco Bemporad, Linlin Qiu, Kaare Teilum, Ngoc-Diep Vu, Aled M. Edwards, Ingo Ruczinski, Flemming M. Poulsen, Birthe Brandt Kragelund, Stephen W. Michnick, Fabrizio Chiti, Yawen Bai, Stephen J. Hagen, Luis Serrano, Mikael Oliveberg, Daniel P. Raleigh, Pernilla Wittung Stafshede, Sheena E. Radford, Sophie e. Jackson, Tobin R. Sosnick, Susan Margusee, Alan R. Davidson and Kevin W. Plaxco. (2005) Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins Protein Science 14(3):602-616.

378.

Kresten Lindorff-Larsen, Robert B. Best and Michele Vendruscolo. (2005) Interpreting Dynamically-Averaged Scalar Couplings in Proteins Journal of Biomolecular NMR 32(4):273-280.

379.

Kresten Lindorff-Larsen, Robert B. Best, M. A. DePristo, C. M. Dobson and Michele Vendruscolo. (2005) Simultaneous determination of protein structure and dynamics Nature 433(7022):128-132.

380.

M. M. Dedmon, K. Lindorff-Larsen, J. Christodoulou, Michele Vendruscolo and C. M. Dobson. (2005) Mapping Long-Range Interactions in a-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations Journal of the American Chemical Society 127(2):476-477.

381.

S. Kristjansdottir, Kresten Lindorff-Larsen, W. Fieber, Christopher M. Dobson, Michele Vendruscolo and Flemming M. Poulsen. (2005) Formation of Native and Non-native Interactions in Ensembles of Denatured ACBP Molecules from Paramagnetic Relaxation Enhancement Studies Journal of Molecular Biology 347(5):1053-1062.

382.

S. Rønhede, Bo Jensen, Søren Rosendahl, Birthe Brandt Kragelund, Rene K. Juhler and J. Aamand. (2005) Hydroxylation of the Herbicide Isoproturon by Fungi Isolated from Agricultural soil Applied and Environmental Microbiology 71(12):7927-7932.

383.

Wolfgang Fieber, Birthe Brandt Kragelund, Morten Peter Meldal and Flemming M. Poulsen. (2005) Reversible Dimerization of Acid-Denatured ACBP Controlled by Helix A4 Biochemistry 44(5):1375-1384.

2004

384.

Emanuele Paci, Claire T Friel, Kresten Lindorff-Larsen, Sheena E Radford, Martin Karplus and Michele Vendruscolo. (2004) Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all-atom molecular dynamics simulations with phi value restraints Proteins: Structure, Function, and Bioinformatics 54(3):513-25.

385.

Kresten Lindorff-Larsen, Michele Vendruscolo, Emanuele Paci and Christopher M Dobson. (2004) Transition states for protein folding have native topologies despite high structural variability Nature Structural and Molecular Biology 11(5):443-9.

386.

Kresten Lindorff-Larsen, Sigridur Kristjansdottir, Kaare Teilum, Wolfgang Fieber, Christopher M Dobson, Flemming Martin Poulsen and Michele Vendruscolo. (2004) Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein Journal of the American Chemical Society 126(10):3291-3219.

387.

Pernille Andersen, Birthe B Kragelund, Addie N Olsen, Flemming H Larsen, Nam-Hai Chua, Flemming M Poulsen and Karen Skriver. (2004) Structure and biochemical function of a prototypical Arabidopsis U-box domain Journal of Biological Chemistry 279(38):40053-40061.

2003

388.

Caroline F Wright, Kresten Lindorff-Larsen, Lucy G Randles and Jane Clarke. (2003) Parallel protein-unfolding pathways revealed and mapped Nature Structural and Molecular Biology 10(8):658-62.

389.

Kresten Lindorff-Larsen, Emanuele Paci, Luis Serrano, Christopher M Dobson and Michele Vendruscolo. (2003) Calculation of mutational free energy changes in transition states for protein folding Biophysical Journal 85(2):1207-14.

2002

390.

Jens K Thomsen, Birthe B Kragelund, Kaare Teilum, Jens Knudsen and Flemming M Poulsen. (2002) Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH Journal of Molecular Biology 318(3):805-14.

391.

Kaare Teilum, Birthe B Kragelund and Flemming M Poulsen. (2002) Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling Journal of Molecular Biology 324(2):349-57.

392.

Kaare Teilum, Kosuke Maki, Birthe B Kragelund, Flemming M Poulsen and Heinrich Roder. (2002) Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing Proceedings of the National Academy of Science of the United States of America 99(15):9807-12.

393.

M.C. Wadum, J.K. Villadsen, S. Feddersen, R.S. Moller, T.B. Neergaard, Birthe Brandt Kragelund, P. Hojrup, N.J. Faergeman and J. Knudsen. (2002) Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids Biochemical Journal 365:165-172.

2001

394.

A Henriksen, O Mirza, C Indiani, K Teilum, G Smulevich, K G Welinder and M Gajhede. (2001) Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions Protein Science 10(1):108-15.

395.

Kresten Lindorff-Larsen and Jakob R. Winther. (2001) Surprisingly high stability of barley lipid transfer protein, LTP1, towards denaturant, heat and proteases FEBS Letters 488(3):145-148.

396.

Kresten Lindorff-Larsen, Mathilde H. Lerche, Flemming Martin Poulsen, Peter Roepstorff and Jakob R. Winther. (2001) Barley lipid transfer protein, LTP1, contains a new type of lipid-like post-translational modification Journal of Biological Chemistry 276(36):33547-53.

2000

397.

B B Kragelund, A Hauenschild, G Carlström, O Pongs and B E Finn. (2000) 1H, 13C, and 15N assignments of un-myristoylated Ca2+-frequenin, a synaptic efficacy modulator Journal of Biomolecular N M R 16(1):85-6.

398.

K Teilum, B B Kragelund, J Knudsen and F M Poulsen. (2000) Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP Journal of Molecular Biology 301(5):1307-14.

399.

Kresten Lindorff-Larsen and Jakob R. Winther. (2000) Thiol alkylation below neutral pH Analytical Biochemistry 286(2):308-10.

400.

L Ostergaard, K Teilum, O Mirza, O Mattsson, M Petersen, K G Welinder, J Mundy, M Gajhede and A. Henriksen. (2000) Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification. Plant Molecular Biology 44(2):231-43.

1999

401.

B B Kragelund, J Knudsen and F M Poulsen. (1999) Acyl-coenzyme A binding protein (ACBP) B B A - Reviews on Cancer 1441:150-61.

402.

Birthe Brandt Kragelund, Peter Osmark, Thomas B. Neergaard, Jacob Schiødt, Karsten Kristiansen, Jens Knudsen and Flemming Poulsen. (1999) The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP Nature Structural and Molecular Biology 6(6):594-601.

403.

K Teilum, L Ostergaard and K G Welinder. (1999) Disulfide bond formation and folding of plant peroxidases expressed as inclusion body protein in Escherichia coli thioredoxin reductase negative strains Protein Expression and Purification 15(1):77-82.

1998

404.

B B Kragelund, M Jönsson, G Bifulco, W J Chazin, H Nilsson, B E Finn and S Linse. (1998) Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation Biochemistry 37(25):8926-37.

405.

Birthe Brandt Kragelund, B. Heinemann, J. Knudsen and Flemming Poulsen. (1998) Mapping the lifetimes of local opening events in a native state protein Protein Sci.(7):2237-2248.

1997

406.

M.H. Lerche, Birthe Brandt Kragelund, L. Bech and Flemming Poulsen. (1997) Structure of lipid-transfer protein complexed with palmitoyl-CoA. A hydrophobic binding site expandable to fit both large and small lipid-like ligands Structure(5):291-306.

1996

407.

Birthe Brandt Kragelund, P. Højrup, M.S. Jensen, C.K. Schjerling, E. Juul, J. Knudsen and Flemming Poulsen. (1996) Fast and one-step folding of closely and distantly related homologous proteins of a four-helix bundle family J. Mol. Biol.(256):187-200.

408.

C.R. Robinson, E.W. Chung, Birthe Brandt Kragelund, J. Knudsen, R.T. Aplin, Flemming Poulsen and C.M. Dobson. (1996) Probing the nature of non-covalent interactions by mass spectrometry. A study of protein-CoA ligand interactions and assembly J. Amer. Chem.(118):8646-8653.

409.

Nils J. Færgeman, B.W. Sigurskjold, Birthe Brandt Kragelund, K.V. Andersen and J. Knudsen. (1996) Thermodynamics of ligand binding to acyl-coenzyme, A binding protein studied by titration calometry Biochemistry(35):14118-14126.

1995

410.

Birthe Brandt Kragelund, C.R. Robinson, J. Knudsen, C.M. Dobson and Flemming Poulsen. (1995) Folding of a four-helix bundle. Studies of acyl-coenzyme A binding protein Biochemistry(34):7217-7224.

411.

Birthe Brandt Kragelund, J. Knudsen and Flemming Poulsen. (1995) Local perturbations by ligand binding on hydrogen exchange kinetics in a four-helix bundle protein, acyl-coenzyme A binding protein (ACBP) J. Mol. Biol.(250):695-706.

1993

412.

Birthe Brandt Kragelund, K.V. Andersen, J.C. Madsen, J. Knudsen and Flemming Poulsen. (1993) Threedimensional structure of the complex acyl-coenzyme, A binding protein and palmitoyl-coenzyme A J. Mol. Biol.(230):1260-1277.

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