Functional Genomics

  1. 2010
  2. Published

    Getting the best out of long-wavelength X-rays: de novo chlorine/sulfur SAD phasing of a structural protein from ATV

    Goulet, A., Vestergaard, G. A., Felisberto-Rodrigues, C., Campanacci, V., Garrett, Roger Antony, Cambillau, C. & Ortiz-Lombardía, M., 2010, In: Acta Crystallographica. Section D: Biological Crystallography. 66, Pt 3, p. 304-308 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    MicroRNA-145 targets YES and STAT1 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus

    Gresham, D., Usaite, R., Germann, S. M., Lisby, Michael, Botstein, D. & Regenberg, Birgitte, 2010, In: Proceedings of the National Academy of Science of the United States of America. 107, 43, p. 18551-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Familial relationships in hyperthermo- and acidophilic archaeal viruses

    Happonen, L. J., Redder, P., Peng, Xu, Reigstad, L. J., Prangishvili, D. & Butcher, S. J., 1 May 2010, In: Journal of Virology. 84, 9, p. 4747-54 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    [Pregnancy within the uterine scar of a prior Caesarean section].

    Hartwell, D., Hoffmann, Eva, Krebs, Lone, Langhoff-Roos, J. & Petersen, K., Aug 2010, In: Ugeskrift for Laeger.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    miRMaid: a unified programming interface for microRNA data resources

    Jacobsen, A., Krogh, Anders, Kauppinen, S. & Lindow, M., 2010, In: BMC Bioinformatics. 11, Suppl 1, p. 29

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    NAC genes: Time-specific regulators of hormonal signaling in Arabidopsis

    Jensen, M. K., Kjærsgaard, T., Petersen, K. & Skriver, Karen, 2010, In: Plant Signalling & Behavior. 5, 7, 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria

    Kaminska, K. H., Purta, E., Hansen, L. H., Bujnicki, J. M., Vester, B. & Long, K. S., 2010, In: Nucleic Acids Research. 38, 5, p. 1652-1663 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Gene expression profiles in rice roots under low phosphorus stress

    Li, L., Liu, C. & Lian, X., 2010, In: Plant Molecular Biology. 72, 4-5, p. 423-432 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The fate of irreparable DNA double-strand breaks and eroded telomeres at the nuclear periphery

    Lisby, Michael, Teixeira, T., Gilson, E. & Géli, V., 2010, In: Nucleus (Austin, Tex.). 1, 2, p. 158-161 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance

    Long, K. S., Munck, C., Andersen, T. M. B., Schaub, M. A., Hobbie, S. N., Böttger, E. C. & Vester, B., 2010, In: Antimicrobial Agents and Chemotherapy. 54, 11, p. 4705-4713 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A long-standing Pleistocene refugium in southern Africa and a mosaic of refugia in East Africa: insights from mtDNA and the common eland antelope

    Lorenzen, Eline, Masembe, C., Arctander, P. & Siegismund, Hans Redlef, 2010, In: Journal of Biogeography. 37, 3, p. 571-581 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Lazarus1, a DUF300 protein, contributes to programmed cell death associated with Arabidopsis acd11 and the hypersensitive response

    Malinovsky, F. G., Brodersen, P., Fiil, Berthe Katrine, McKinney, L. V., Thorgrimsen, S., Beck, M., Nielsen, H. B., Pietra, S., Zipfel, C., Robatzek, S., Petersen, Morten, Hofius, D. & Mundy, J., 2010, In: P L o S One. 5, 9, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

    Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus

    Motti, D., Le Duigou, C., Eugène, E., Chemaly, N., Wittner, L., Lazarevic, D., Krmac, H., Marstrand, T., Valen, E., Sanges, R., Stupka, E., Sandelin, Albin Gustav, Cherubini, E., Gustincich, S. & Miles, R., 2010, In: European Journal of Neuroscience. 32, 8, p. 1364-79 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The Scottish Structural Proteomics Facility: targets, methods and outputs

    Oke, M., Carter, L. G., Johnson, K. A., Liu, H., McMahon, S. A., Yan, X., Kerou, M., Weikart, N. D., Kadi, N., Sheikh, M. A., Schmelz, S., Dorward, M., Zawadzki, M., Cozens, C., Falconer, H., Powers, H., Overton, I. M., van Niekerk, C. A. J., Peng, X., Patel, P. & 11 others, Garrett, Roger Antony, Prangishvili, D., Botting, C. H., Coote, P. J., Dryden, D. T. F., Barton, G. J., Schwarz-Linek, U., Challis, G. L., Taylor, G. L., White, M. F. & Naismith, J. H., 1 Jun 2010, In: Journal of Structural and Functional Genomics. 11, 2, p. 167-80 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Autoimmunity in Arabidopsis acd11 is mediated by epigenetic regulation of an immune receptor

    Palma, K., Thorgrimsen, S., Malinovsky, F. G., Fiil, Berthe Katrine, Nielsen, H. B., Brodersen, P., Hofius, D., Petersen, Morten & Mundy, J., 1 Jan 2010, In: P L o S Pathogens. 6, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function

    Petersen, K., Qiu, J., Lütje, J., Fiil, Berthe Katrine, Hansen, S., Mundy, J. & Petersen, Morten, 1 Jan 2010, In: P L o S One. 5, 12, p. e14364

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Mitogen-activated protein kinase signaling in plants

    Rodriguez, M. C. S., Petersen, Morten & Mundy, J., 2010, In: Annual Review of Plant Biology. 61, 1, p. 621-649 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

    Ruzzin, J., Petersen, R., Meugnier, E., Madsen, L., Lock, E., Lillefosse, H., Ma, T., Pesenti, S., Sonne, Si Brask, Marstrand, T. T., Malde, M. K., Du, Z., Chavey, C., Fajas, L., Lundebye, A., Brand, C. L., Vidal, H., Kristiansen, Karsten & Frøyland, L., 2010, In: Environmental Health Perspectives. 118, 4, p. 465-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia

    Stephens, N. A., Gallagher, I. J., Rooyackers, O., Skipworth, R. J., Tan, B. H., Marstrand, T. T., Ross, J. A., Guttridge, D. C., Lundell, L., Fearon, K. C. & Timmons, J. A., 2010, In: Genome Medicine. 2, 12 p., 1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Transcriptomes of the desiccation-tolerant resurrection plant Craterostigma plantagineum

    Suarez Rodriguez, M. C., Edsgärd, D., Hussain, S. S., Alquezar Planas, D. E., Rasmussen, M., Gilbert, M Thomas P, Nielsen, B. H., Bartels, D. & Mundy, J., Jul 2010, In: The Plant Journal. 63, 2, p. 212-228 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method

    Zhang, C., Guo, L., Deng, L., Wu, Y., Liang, Y., Huang, L. & She, Q., Nov 2010, In: Microbiology. 156, Part 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A bacterial ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility

    ZHANG, YONG, Franco, M., Ducret, A. & Mignot, T., Jul 2010, In: PLOS Biology. 8, 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The rad52-Y66A allele alters the choice of donor template during spontaneous chromosomal recombination

    de Mayolo, A. A., Sunjevaric, I., Reid, R., Mortensen, U. H., Rothstein, R. & Lisby, Michael, 2010, In: DNA Repair. 9, 1, p. 23-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2011
  29. Published

    C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family

    Contursi, P., D'Ambrosio, K., Pirone, L., Pedone, E., Aucelli, T., She, Q., De Simone, G. & Bartolucci, S., 2011, In: Biochemical Journal. 435, 1, p. 157-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Cell biology of homologous recombination in yeast

    Eckert-Boulet, N. V., Rothstein, R. & Lisby, Michael, 2011, DNA recombination: methods and protocols. Tsubouchi, H. (ed.). Springer, p. 523-536 14 p. (Methods in Molecular Biology, Vol. 745).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Published

    AAA ATPase p529 of Acidianus two-tailed virus ATV and host receptor recognition

    Erdmann, S., Scheele, U. & Garrett, Roger Antony, 2011, In: Virology. 421, 1, p. 61-66 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Nucleotide diversity and linkage disequilibrium of nine genes with putative effects on flowering time in perennial ryegrass (Lolium perenne L.)

    Fiil, A., Lenk, I., Petersen, K., Jensen, C. S., Nielsen, K. K., Schejbel, B., Andersen, J. R. & Lübberstedt, T., 2011, In: Plant Science. 180, 2, p. 228-237 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Archaeal CRISPR-based immune systems: exchangeable functional modules

    Garrett, Roger Antony, Vestergaard, G. A. & Shah, S. A., 2011, In: Trends in Microbiology. 19, 11, p. 549-56 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    CRISPR-based immune systems of the Sulfolobales: complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Vestergaard, G. A., Deng, Ling, Guðbergsdóttir, S. R., Kenchappa, C. S., Erdmann, S. & She, Q., 2011, In: Biochemical Society Transactions. 39, 1, p. 51-57 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination

    Germann, S. M., Østergaard, Vibe Hallundbæk, Haas, C., Salis, P., Motegi, A. & Lisby, Michael, 2011, In: D N A Repair. 10, 2, p. 210-224 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Genome Analyses of Icelandic Strains of Sulfolobus islandicus, Model Organisms for Genetic and Virus-Host Interaction Studies

    Guo, L., Brügger, K., Liu, C., Shah, S. A., Zheng, H., Zhu, Y., Wang, S., Lillestøl, R. K., Chen, L., Frank, J., Prangishvili, D., Paulin, L., She, Q., Huang, L. & Garrett, Roger Antony, 1 Apr 2011, In: Journal of Bacteriology. 193, 7, p. 1672-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers

    Guðbergsdóttir, S. R., Deng, L., Chen, Z., Jensen, J. V. K., Jensen, L. R., She, Q. & Garrett, Roger Antony, 2011, In: Molecular Microbiology. 79, 1, p. 35-49 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases

    Hansen, K. R., Hazan, I., Shanker, S., Watt, S., Hansen, J. V., Bähler, J., Martienssen, R. A., Partridge, J. F., Cohen, A. & Thon, Genevieve, 2011, In: P L o S Genetics. 7, 1, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Role of autophagy in disease resistance and hypersensitive response-associated cell death

    Hofius, D., Munch, D., Bressendorff, Simon, Mundy, J. & Petersen, Morten, 2011, In: Cell Death and Differentiation. 18, 8, p. 1257-1262 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Phenylbutyrate inhibits homologous recombination induced by camptothecin and methyl methanesulfonate

    Kaiser, G. S., Germann, S. M., Westergaard, T. & Lisby, Michael, 2011, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 713, 1-2, p. 64-75 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain

    Kjaersgaard, T., Jensen, M. K., Christiansen, M. W., Gregersen, P. L., Kragelund, Birthe Brandt & Skriver, Karen, 2011, In: Journal of Biological Chemistry. 286, 41, p. 35418-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control

    Li, X., Guo, L., Deng, Ling, Feng, D., Ren, Y., Chu, Y., She, Q. & Huang, L., 2011, In: Journal of Genetics and Genomics. 38, 6, p. 253-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

    Lintner, N. G., Kerou, M., Brumfield, S. K., Graham, S., Liu, H., Naismith, J. H., Sdano, M., Peng, N., She, Q., Copié, V., Young, M. J., White, M. F. & Lawrence, C. M., 2011, In: The Journal of Biological Chemistry. 286, 24, p. 21643-56 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication

    Oke, M., Kerou, M., Liu, H., Peng, Xu, Garrett, Roger Antony, Prangishvili, D., Naismith, J. H. & White, M. F., 2011, In: Journal of Virology. 85, 2, p. 925-31 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Generative probabilistic models extend the scope of inferential structure determination

    Olsson, S., Boomsma, Wouter, Frellsen, J., Bottaro, S., Harder, T. P., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2011, In: Journal of Magnetic Resonance. 213, 1, p. 182-186 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  46. Published

    Archaeal promoter architecture and mechanism of gene activation

    Peng, N., Ao, X., Liang, Y. X. & She, Q., 19 Jan 2011, In: Biochemical Society Transactions. 39, 1, p. 99-103 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Bird and plant companion species predict breeding and migrant habitats of the genus Oenanthe

    Pentzold, S., Pentzold, C. & Randler, C., 2011, In: Journal of Ecology and Field Biology. 34, 3, p. 287-293 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Chaperone role for proteins p618 and p892 in the extracellular tail development of Acidianus two-tailed virus

    Scheele, U., Erdmann, S., Ungewickell, E. J., Felisberto-Rodrigues, C., Ortiz-Lombardía, M. & Garrett, Roger Antony, 2011, In: Journal of Virology. 85, 10, p. 4812-4821 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    CRISPR/Cas and Cmr modules, mobility and evolution of adaptive immune systems

    Shah, S. A. & Garrett, Roger Antony, 2011, In: Research in Microbiology. 162, 1, p. 27-38 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Sulfolobus Turreted Icosahedral Virus c92 Protein Responsible for the Formation of Pyramid-Like Cellular Lysis Structures

    Snyder, J. C., Brumfield, S. K., Peng, N., She, Q. & Young, M. J., 2011, In: Journal of Virology. 85, 13, p. 6287-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

    Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, Christian, Murray, J. M., Carr, A. M. & Nielsen, Olaf, 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles

    You, X. Y., Liu, C., Wang, S. Y., Jiang, C. Y., Shah, S. A., Prangishvili, D., She, Q., Liu, S. J. & Garrett, Roger Antony, 2011, In: Extremophiles. 15, p. 487-497 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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