Functional Genomics

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  1. Published

    Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response

    Bærentsen, R. L., Brodersen, D. E. & ZHANG, YONG, 2019, In: Microbial Cell Factories. 6, 9, p. 450-453

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes.

    Siepel, A., Bejerano, G., Pedersen, J. S., Hinrichs, A. S., Hou, M., Rosenbloom, K., Clawson, H., Spieth, J., Hillier, L. W., Richards, S., Weinstock, G. M., Wilson, R. K., Gibbs, R. A., Kent, W. J., Miller, W. & Haussler, D., 2005, In: Genome Research. 15, 8, p. 1034-50 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants

    Makarova, K. S., Wolf, Y. I., Iranzo, J., Shmakov, S. A., Alkhnbashi, O. S., Brouns, S. J. J., Charpentier, E., Cheng, D., Haft, D. H., Horvath, P., Moineau, S., Mojica, F. J. M., Scott, D., Shah, S. A., Siksnys, V., Terns, M. P., Venclovas, Č., White, M. F., Yakunin, A. F., Yan, W. & 6 others, Zhang, F., Garrett, Roger Antony, Backofen, R., van der Oost, J., Barrangou, R. & Koonin, E. V., 2020, In: Nature Reviews. Microbiology. 18, p. 67-83

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Examination of bacterial growth rate during host infection and its importance for antimicrobial treatment

    Haugan, M. S., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  5. Published

    Examination of the Regulation and Function of TopBP1 during Mitotic DNA Repair

    Bagge, J., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 124 p.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host

    Mei, Y., Peng, N., Zhao, S., Hu, Y., Wang, H., Liang, Y. & She, Q., 2012, In: Applied Microbiology and Biotechnology. 93, 5, p. 1965-1974 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Exceptionally diverse morphotypes and genomes of crenarchaeal hyperthermophilic viruses

    Prangishvili, D. & Garrett, Roger Antony, 2004, In: Biochemical Society Transactions. 32, Pt 2, p. 204-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells

    Brunati, C., Thomsen, T. T., Gaspari, E., Maffioli, S., Sosio, M., Jabes, D., Løbner-Olesen, Anders & Donadio, S., 2018, In: The Journal of antimicrobial chemotherapy. 73, 2, p. 414-424 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Exposure to Cr(VI) induces organ dependent MSI in two loci related with photophosphorylation and with glutamine metabolism

    Rodriguez, E., Azevedo de Silva, R., Remédios, C., Almeida, T., Fernandes, P. & Santos, C., 2013, In: Journal of Plant Physiology. 170, 5, p. 534-538 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Expression of the Escherichia coli dam gene

    Løbner-Olesen, Anders, Boye, E. & Marinus, M. G., Jul 1992, In: Molecular Microbiology. 6, 13, p. 1841-51 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Extreme genetic differences among populations of Gazella granti, Grant's gazelle in Kenya

    Arctander, P., Kat, P. W., Aman, R. A. & Siegismund, Hans Redlef, 1996, In: Heredity. 76 ( Pt 5), p. 465-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe

    Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Apr 1998, In: Journal of Cell Science. 111 ( Pt 7), p. 867-76 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells

    Pentzold, C., Shah, S. A., Hansen, Niels Richard, Le Tallec, B., Seguin-Orlando, A., Debatisse, M., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2018, In: Nucleic Acids Research. 46, 3, p. 1280-1294 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation

    Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Jun 1998, In: Journal of Cell Biology. 141, 5, p. 1217-28 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    FOXP3 positive regulatory T-cells in cutaneous T-cell lymphomas

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels & Ralfkiaer, E., 2008, In: Virchows Archiv. 452, Suppl. 1, p. S4-S4

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Hother, C., Henrik-Nielsen, R., Gniadecki, R. & Ralfkiaer, E., 2008, In: European Journal of Haematology. 80, 6, p. 483-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Burton, C. M., Rossen, K., Skovgaard, G. L., Ryder, L. P. & Ralfkiaer, E., 2007, In: Leukemia. 21, 12, p. 2512-2518 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Familial relationships in hyperthermo- and acidophilic archaeal viruses

    Happonen, L. J., Redder, P., Peng, Xu, Reigstad, L. J., Prangishvili, D. & Butcher, S. J., 1 May 2010, In: Journal of Virology. 84, 9, p. 4747-54 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Fatty acid starvation activates RelA by depleting lysine precursor pyruvate

    Sinha, A. K., Winther, K. S., Roghanian, Mohammad & Gerdes, K., 2019, In: Molecular Microbiology. 112, 4, p. 1339-1349

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    First experimental evidence for the presence of a CRISPR toxin in Sulfolobus

    He, F., Chen, L. & Peng, Xu, 2014, In: Journal of Molecular Biology. 426, 22, p. 3683-3688 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats

    Liaset, B., Madsen, L., Hao, Q., Criales, G., Mellgren, G., Marschall, H., Hallenborg, P., Espe, M., Frøyland, L. & Kristiansen, Karsten, 2009, In: BBA General Subjects. 1791, 4, p. 254-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching

    Maki, T., Thon, Genevieve & Iwasaki, H., 2023, In: Nucleic acids symposium series. 51, 8, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Fission yeast goes synthetic.

    Nielsen, Olaf, 2007, In: Nature Methods. 4, 10, p. 777-8 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Flavour Compounds in Fungi: Flavour Analysis in Ascomycetes and the Contribution of the Ehrlich Pathway to Flavour Production in Saccharomyces cerevisiae and Ashbya gossypii

    Ravasio, D. A., 2014, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  25. Published

    Flow cytometry: illuminating microbiology

    Boye, E. & Løbner-Olesen, Anders, Feb 1990, In: The New Biologist. 2, 2, p. 119-25 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Fluorescence recovery allows theimplementation of a fluorescence reporter gene platform applicable for the detection and quantification of horizontal gene transfer in anoxic environments

    Pinilla Redondo, Rafael, Riber, Leise & Sørensen, Søren Johannes, 2018, In: Applied and Environmental Microbiology. 84, 6, 9 p., e02507-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation

    Bjørnkjær, Lene, Stein, Amelie, Grønbæk-Thygesen, Martin, Nygaard, L., Søltoft, C. L., Nielsen, S. V., Lisby, Michael, Ravid, T., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: PLOS Genetics. 16, 11, 28 p., e1009187.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Forces shaping the fastest evolving regions in the human genome.

    Pollard, K. S., Salama, S. R., King, B., Kern, A. D., Dreszer, T., Katzman, S., Siepel, A., Pedersen, J. S., Bejerano, G., Baertsch, R., Rosenbloom, K. R., Kent, J. & Haussler, D., 2006, In: PLoS Genetics. 2, 10, p. e168

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Formation of a viral replication focus in Sulfolobus cells infected by the rudivirus Sulfolobus islandicus rod-shaped virus 2

    Martinez Alvarez, Laura, Deng, Ling & Peng, Xu, Jul 2017, In: Journal of Virology. 91, 13, 12 p., e00486-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Four additional natural 7-deazaguanine derivatives in phages and how to make them

    Cui, L., Balamkundu, S., Liu, C. F., Ye, H., Hourihan, J., Rausch, A., Hauß, C., Nilsson, E., Hoetzinger, M., Holmfeldt, K., Zhang, W., Martinez-Alvarez, L., Peng, X., Tremblay, D., Moinau, S., Solonenko, N., Sullivan, M. B., Lee, Y. J., Mulholland, A., Weigele, P. R. & 3 others, de Crécy-Lagard, V., Dedon, P. C. & Hutinet, G., 2023, In: Nucleic Acids Research. 51, 17, p. 9214-9226 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism

    Redder, P., Peng, Xu, Brügger, K., Shah, S. A., Roesch, F., Greve, B., She, Q., Schleper, C., Forterre, P., Garrett, Roger Antony & Prangishvili, D., 2009, In: Environmental Microbiology. 11, 11, p. 2849-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Four weeks one-leg training and high fat diet does not alter PPAR alpha protein or mRNA expression in human skeletal muscle

    Helge, Jørn Wulff, Bentley, D., Schjerling, Peter, Willer, M., Gibala, M. J., Franch, J., Tapia-Laliena, M. A., Daugaard, J. R. & Andersen, J. L., 2007, In: European Journal of Applied Physiology. 101, 1, p. 105-114 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A

    Møller, M. B., Kania, Per, Ino, Y., Gerdes, Anne-Marie Axø, Nielsen, Olaf, Louis, D. N., Skjødt, K. & Pedersen, N. T., May 2000, In: Leukemia. 14, 5, p. 898-904 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2

    Leshets, M., Ramamurthy, D., Lisby, Michael, Lehming, N. & Pines, O., 2018, In: Current Genetics. 64, 3, p. 697-712 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs

    Richard, S., Almeida, J. M. G. C. F., Cissé, O. H., Luraschi, A., Nielsen, Olaf, Pagni, M. & Hauser, P. M., 2018, In: mBio. 9, 1, 10 p., e02201-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing.

    Irimia, M., Rukov, J. L., Penny, D. & Roy, S. W., 2007, In: BMC Evolutionary Biology. 7, p. 188

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities

    Guo, Y., Kragelund, Birthe Brandt, White, M. F. & Peng, Xu, 2015, In: Journal of Molecular Biology. 427, 12, p. 2179-2191 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction

    Styrkársdóttir, U., Egel, Richard, Nielsen, O. & Nielsen, Olaf, 1 Oct 1992, In: Molecular and General Genetics MGG. 235, 1, p. 122-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Functional study of PAT mRNA decapping factors in Arabidopsis

    Zuo, Zhangli Thomsen, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  40. Published

    Functions of Orc1-2 in the DNA damageresponsive regulation in Sulfolobus islandicus

    Sun, M., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  41. Published

    Functions of TopBP1 in preserving genome integrity during mitosis

    Bagge, J., Østergaard, Vibe Hallundbæk & Lisby, Michael, 2021, In: Seminars in Cell and Developmental Biology. 113, p. 57-64 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes

    Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, Anders , Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Gene Expression Changes with Minor Effects on the Population Average Have Major Effects on the Occurrence of Cells with Extreme Protein Concentrations

    Svenningsen, Mikkel Skjoldan, Semsey, S. & Mitarai, Namiko, 2019, In: mSphere. 4, 1, p. 1-6 e00575-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus

    Motti, D., Le Duigou, C., Eugène, E., Chemaly, N., Wittner, L., Lazarevic, D., Krmac, H., Marstrand, T., Valen, E., Sanges, R., Stupka, E., Sandelin, Albin Gustav, Cherubini, E., Gustincich, S. & Miles, R., 2010, In: European Journal of Neuroscience. 32, 8, p. 1364-79 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Gene expression profiles in rice roots under low phosphorus stress

    Li, L., Liu, C. & Lian, X., 2010, In: Plant Molecular Biology. 72, 4-5, p. 423-432 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Gene finding with a hidden Markov model of genome structure and evolution.

    Pedersen, J. S. & Hein, J., 2003, In: Bioinformatics. 19, 2, p. 219-27 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Gene regulation by MAP kinase cascades

    Fiil, Berthe Katrine, Petersen, K., Petersen, Morten & Mundy, J., 2009, In: Current Opinion in Plant Biology. 12, 5, p. 615-621 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Generative probabilistic models extend the scope of inferential structure determination

    Olsson, S., Boomsma, Wouter, Frellsen, J., Bottaro, S., Harder, T. P., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2011, In: Journal of Magnetic Resonance. 213, 1, p. 182-186 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  49. Published

    Genetic Studies on CRISPR-Cas Functions in Invader Defense in Sulfolobus islandicus

    Peng, W., 2015, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  50. Published

    Genetic analyses in the hyperthermophilic archaeon Sulfolobus islandicus

    She, Q., Zhang, C., Deng, L., Peng, N., Chen, Z. & Liang, Y. X., 2009, In: Biochemical Society Transactions. 37, Pt 1, p. 92-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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