Functional Genomics

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  1. 2007
  2. Published

    Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

    Birney, E., Stamatoyannopoulos, J. A., Dutta, A., Guigó, R., Gingeras, T. R., Margulies, E. H., Weng, Z., Snyder, M., Dermitzakis, E. T., Thurman, R. E., Kuehn, M. S., Taylor, C. M., Neph, S., Koch, C. M., Asthana, S., Malhotra, A., Adzhubei, I., Greenbaum, J. A., Andrews, R. M., Flicek, P. & 36 others, Boyle, P. J., Cao, H., Carter, N. P., Clelland, G. K., Davis, S., Day, N., Dhami, P., Dillon, S. C., Dorschner, M. O., Fiegler, H., Giresi, P. G., Goldy, J., Hawrylycz, M., Haydock, A., Humbert, R., James, K. D., Johnson, B. E., Johnson, E. M., Frum, T. T., Rosenzweig, E. R., Karnani, N., Lee, K., Lefebvre, G. C., Navas, P. A., Neri, F., Parker, S. C. J., Sabo, P. J., Sandstrom, R., Sandelin, Albin Gustav, Pedersen, J. S., ENCODE Project Consortium, E. P. C., NISC Comparative Sequencing Program, N. C. S. P., Baylor College of Medicine Human Genome Sequencing Center, B. C. O. M. H. G. S. C., Washington University Genome Sequencing Center, W. U. G. S. C., Broad Institute, B. I. & Children's Hospital Oakland Research Institute, C. H. O. R. I., 2007, In: Nature. 447, 7146, p. 799-816 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    KBERG: KnowledgeBase for Estrogen Responsive Genes.

    Tang, S., Zhang, Z., Tan, S. L., Tang, M. E., Kumar, A. P., Ramadoss, S. K. & Bajic, V. B., 2007, In: Nucleic Acids Research. 35, Database issue, p. D732-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Mammalian RNA polymerase II core promoters: insights from genome-wide studies.

    Sandelin, Albin Gustav, Carninci, P., Lenhard, B., Ponjavic, J., Hayashizaki, Y. & Hume, D. A., 2007, In: Nature Reviews. Genetics. 8, 6, p. 424-36 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Molecular composition of IMP1 ribonucleoprotein granules.

    Jønson, L., Vikesaa, J., Krogh, Anders, Nielsen, Lars Kamp, Hansen, T. V., Borup, R., Johnsen, A. H., Christiansen, Jan & Nielsen, Finn Cilius, 2007, In: Molecular and Cellular Proteomics. 6, 5, p. 798-811 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

    Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Novel bacterial sulfur oxygenase reductases from bioreactors treating gold-bearing concentrates

    Chen, Z., Liu, Y., Wu, J., She, Q., Jiang, C. & Liu, S., 2007, In: Applied Microbiology and Biotechnology. 74, 3, p. 688-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Phylogeography, hybridization and Pleistocene refugia of the kob antelope (Kobus kob)

    Lorenzen, E. D., De Neergaard, R., Arctander, P. & Siegismund, Hans Redlef, 2007, In: Molecular Ecology. 16, 15, p. 3241-52 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Population genetic structure of the common warthog (Phacochoerus africanus) in Uganda: evidence for a strong philopatry among warthogs and social structure breakdown in a disturbed population

    Muwanka, V. B., Nyakaana, S., Siegismund, Hans Redlef & Arctander, P., 2007, In: African Journal of Ecology. 45, 1, p. 22-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Rad52 and Rad59 exhibit both overlapping and distinct functions

    Feng, Q., Düring, L., Mayolo, A. A. D., Lettier, G., Lisby, Michael, Erdeniz, N., Mortensen, U. H. & Rothstein, R., 2007, In: DNA Repair. 6, 1, p. 27-37

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Rad52 and Rad59 exhibit both overlapping and distinct functions

    Feng, Q., Düring, L., de Mayolo, A. A., Buchhorn, G. L., Lisby, Michael, Erdeniz, N., Mortensen, U. H. & Rothstein, R., 2007, In: DNA Repair. 6, 1, p. 27-37 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Rad52 multimerization is important for its nuclear localization in Saccharomyces cerevisiae.

    Plate, I., Albertsen, L., Lisby, Michael, Hallwyl, S. C. L., Feng, Q., Seong, C., Rothstein, R., Sung, P. & Mortensen, U. H., 2007, In: DNA Repair. 7, 1, p. 57-66 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Stability of Barley stripe mosaic virus-induced gene silencing in barley.

    Bruun-Rasmussen, M., Madsen, C. T., Jessing, S. & Albrechtsen, M. T., 2007, In: Molecular Plant - Microbe Interactions. 20, 11, p. 1323-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Structured RNAs in the ENCODE selected regions of the human genome.

    Washietl, S., Pedersen, J. S., Korbel, J. O., Stocsits, C., Gruber, A. R., Hackermüller, J., Hertel, J., Lindemeyer, M., Reiche, K., Tanzer, A., Ucla, C., Wyss, C., Antonarakis, S. E., Denoeud, F., Lagarde, J., Drenkow, J., Kapranov, P., Gingeras, T. R., Guigó, R., Snyder, M. & 4 others, Gerstein, M. B., Reymond, A., Hofacker, I. L. & Stadler, P. F., 2007, In: Genome Research. 17, 6, p. 852-64 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination.

    Burgess, R. C., Rahman, S., Lisby, Michael, Rothstein, R. & Zhao, X., 2007, In: Molecular and Cellular Biology. 27, 17, p. 6153-62 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus.

    Torres-Rosell, J., Sunjevaric, I., De Piccoli, G., Sacher, M., Eckert-Boulet, N., Reid, R., Jentsch, S., Rothstein, R., Aragón, L. & Lisby, Michael, 2007, In: Nature Cell Biology. 9, 8, p. 923-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The UCSC Genome Browser Database: 2008 update.

    Karolchik, D., Kuhn, R. M., Baertsch, R., Barber, G. P., Clawson, H., Diekhans, M., Giardine, B., Harte, R. A., Hinrichs, A. S., Hsu, F., Kober, K. M., Miller, W., Pedersen, J. S., Pohl, A., Raney, B. J., Rhead, B., Rosenbloom, K. R., Smith, K. E., Stanke, M., Thakkapallayil, A. & 5 others, Trumbower, H., Wang, T., Zweig, A. S., Haussler, D. & Kent, W. J., 2007, In: Nucleic Acids Research. 36, Database issue, p. D773-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C

    Brügger, K., Chen, L., Stark, M., Zibat, A., Redder, P., Ruepp, A., Awayez, M., She, Q., Garrett, Roger Antony & Klenk, H., 2007, In: Archaea. 2, 2, p. 127-35 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Theoretical analysis of epigenetic cell memory by nucleosome modification

    Dodd, I. B., Micheelsen, M. A., Sneppen, Kim & Thon, Genevieve, 2007, In: Cell. 129, 4, p. 813-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Transcriptional Analysis of the Genetic Element pSSVx: Differential and Temporal Regulation of Gene Expression Reveals Correlation between Transcription and Replication

    Contursi, P., Cannio, R., Prato, S., She, Q., Rossi, M. & Bartolucci, S., 2007, In: Journal of Bacteriology. 189, 17, p. 6339-50 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Using an alignment of fragment strings for comparing protein structures.

    Friedberg, I., Harder, T., Kolodny, R., Sitbon, E., Li, Z. & Godzik, A., 2007, In: Bioinformatics. 23, 2, p. e219-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2006
  23. Published

    Viruses of the Archaea: a unifying view

    Prangishvili, D., Forterre, P. & Garrett, Roger Antony, 1 Nov 2006, In: Nature Reviews. Microbiology. 4, 11, p. 837-48 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae

    Lettier, G., Feng, Q., De Mayolo, A. A., Erdeniz, N., Reid, R. J. D., Lisby, Michael, Mortensen, U. H. & Rothstein, R., Nov 2006, In: PLOS Genetics. 2, 11, p. 1773-1786 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40

    Simpson, L. J., Ross, A. L., Szüts, D., Alviani, C. A., Østergaard, Vibe Hallundbæk, Patel, K. J. & Sale, J. E., 1 Sep 2006, In: EMBO Reports. 7, 9, p. 927-932 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Mediastinalt parathyroideacysteadenom--en sjaelden årsag til primaer hyperparatyroidisme

    Øgard, C. G., Nielsen, S. L., Jakobsen, H., Leth-Espensen, P., drb459, drb459 & drb459, drb459, 28 Aug 2006, In: Ugeskrift for Laeger. 168, 35, p. 2921-2 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In: Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A putative flavin-containing mono-oxygenase as a marker for certain defense and cell death pathways

    Olszak, B., Malinovsky, F. G., Brodersen, P., Grell, M., Giese, H., Petersen, Morten & Mundy, J., 2006, In: Plant Science. 170, 3, p. 614-623

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A putative viral defence mechanism in archaeal cells

    Lillestøl, R. K., Redder, P., Garrett, Roger Antony & Brügger, K., 2006, In: Archaea. 2, 1, p. 59-72 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    An RNA gene expressed during cortical development evolved rapidly in humans.

    Pollard, K. S., Salama, S. R., Lambert, N., Lambot, M., Coppens, S., Pedersen, J. S., Katzman, S., King, B., Onodera, C., Siepel, A., Kern, A. D., Dehay, C., Igel, H., Ares, M., Vanderhaeghen, P. & Haussler, D., 2006, In: Nature. 443, 7108, p. 167-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4

    Brodersen, K. P., Petersen, Morten, Nielsen, H. B., Zhu, S., Newman, Mari-Anne, Shokat, K. M., Rietz, S., Parker, J. & Mundy, J., 2006, In: Plant Journal. 47, 4, p. 532-546 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV)

    Goulet, A., Spinelli, S., Campanacci, V., Porciero, S., Blangy, S., Garrett, Roger Antony, van Tilbeurgh, H., Leulliot, N., Basta, T., Prangishvili, D. & Cambillau, C., 2006, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 62, Pt 9, p. 884-886 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Dynamic usage of transcription start sites within core promoters.

    Kawaji, H., Frith, M. C., Katayama, S., Sandelin, Albin Gustav, Kai, C., Kawai, J., Carninci, P. & Hayashizaki, Y., 2006, In: Genome Biology. 7, 12, p. R118

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Forces shaping the fastest evolving regions in the human genome.

    Pollard, K. S., Salama, S. R., King, B., Kern, A. D., Dreszer, T., Katzman, S., Siepel, A., Pedersen, J. S., Bejerano, G., Baertsch, R., Rosenbloom, K. R., Kent, J. & Haussler, D., 2006, In: PLoS Genetics. 2, 10, p. e168

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

    Zhu, X., Wirén, M., Sinha, I., Rasmussen, N. N., Linder, T., Holmberg, Steen, Ekwall, K. & Gustafsson, C. M., 2006, In: Molecular Cell. 22, 2, p. 169-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    How to induce non-polarized cells of hepatic origin to express typical hepatocyte polarity: generation of new highly polarized cell models with developed and functional bile canaliculi

    Peng, Xu & Grosse B, Le Tiec B, Nicolas V, Delagebeaudeuf C, Bedda T, Decaens C, Cassio D, G. B. L. T. B. N. V. D. C. B. T. D. C. C. D., 2006, In: Cell and Tissue Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Hybridization between subspecies of waterbuck (Kobus ellipsiprymnus) in zones of overlap with limited introgression

    Lorenzen, Eline, Simonsen, Bo Thisted, Kat, P. W., Arctander, P. & Siegismund, Hans Redlef, 2006, In: Molecular Ecology. 15, 12, p. 3787-99 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Identification and classification of conserved RNA secondary structures in the human genome.

    Pedersen, J. S., Bejerano, G., Siepel, A., Rosenbloom, K., Lindblad-Toh, K., Lander, E. S., Kent, J., Miller, W. & Haussler, D., 2006, In: PLoS Computational Biology. 2, 4, p. e33

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Identification of miRNA targets with stable isotope labeling by amino acids in cell culture.

    Vinther, Jeppe, Hedegaard, M. M., Gardner, P. P., Andersen, J. S. & Arctander, P., 2006, In: Nucleic Acids Research. 34, 16, p. e107

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Inducible cell death in plant immunity.

    Hofius, D., Tsitsigiannis, D. I., Jones, J. D. G. & Mundy, J., 2006, In: Seminars in Cancer Biology. 17, 2, p. 166-87 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    JAFA: a protein function annotation meta-server.

    Friedberg, I., Harder, T. & Godzik, A., 2006, In: Nucleic Acids Research. 34, Web Server issue, p. W379-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma

    Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Lovato, P., Labuda, T., Eriksen, K. W., Zhang, Q., Becker, J. C. & Ødum, Niels, 2006, In: Leukemia. 20, 10, p. 1759-66 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Novel overlapping coding sequences in Chlamydia trachomatis

    Jensen, K. T., Petersen, L., Falk, S., Iversen, P., Andersen, P., Theisen, Michael & Krogh, Anders, 2006, In: FEMS Microbiology Reviews. 265, 1, p. 106-17

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    RNA-binding IMPs promote cell adhesion and invadopodia formation.

    Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

    Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor

    Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Structural and genomic properties of the hyperthermophilic archaeal virus ATV with an extracellular stage of the reproductive cycle

    Prangishvili, D., Vestergaard, G. A., Häring, M., Aramayo, R., Basta, T., Rachel, R. & Garrett, Roger Antony, 2006, In: Journal of Molecular Biology. 359, 5, p. 1203-1216 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Sulfolobus genomes: mechanisms of rearrangement and change

    Brügger, K., Peng, Xu & Garrett, Roger Antony, 2006, Archaea: Evolution, physiology and Molecular Biolog.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  49. Published

    The UCSC Genome Browser Database: update 2006.

    Hinrichs, A. S., Karolchik, D., Baertsch, R., Barber, G. P., Bejerano, G., Clawson, H., Diekhans, M., Furey, T. S., Harte, R. A., Hsu, F., Hillman-Jackson, J., Kuhn, R. M., Pedersen, J. S., Pohl, A., Raney, B. J., Rosenbloom, K. R., Siepel, A., Smith, K. E., Sugnet, C. W., Sultan-Qurraie, A. & 7 others, Thomas, D. J., Trumbower, H., Weber, R. J., Weirauch, M., Zweig, A. S., Haussler, D. & Kent, W. J., 2006, In: Nucleic Acids Research. 34, Database issue, p. D590-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The UCSC genome browser database: update 2007.

    Kuhn, R. M., Karolchik, D., Zweig, A. S., Trumbower, H., Thomas, D. J., Thakkapallayil, A., Sugnet, C. W., Stanke, M., Smith, K. E., Siepel, A., Rosenbloom, K. R., Rhead, B., Raney, B. J., Pohl, A., Pedersen, J. S., Hsu, F., Hinrichs, A. S., Harte, R. A., Diekhans, M., Clawson, H. & 5 others, Bejerano, G., Barber, G. P., Baertsch, R., Haussler, D. & Kent, W. J., 2006, In: Nucleic Acids Research. 35, Database issue, p. D668-73

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

    Elmlund, H., Baraznenok, V., Lindahl, M., Samuelsen, C. O., Koeck, P. J. B., Holmberg, Steen, Hebert, H. & Gustafsson, C. M., 2006, In: Proceedings of the National Academy of Science of the United States of America. 103, 43, p. 15788-93 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Three genetically divergent lineages of the Oryx in eastern Africa: Evidence for an ancient introgressive hybridization

    Masembe, C., Muwanika, V. B., Nyakaana, S., Arctander, P. & Siegismund, Hans Redlef, 2006, In: Conservation Genetics. 7, 4, p. 551-562

    Research output: Contribution to journal › Journal article › Research › peer-review

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