Functional Genomics

  1. Published

    Basal level of ppGpp coordinates Escherichia coli cell heterogeneity and ampicillin resistance and persistence

    Grucela, Paulina Katarzyna & Zhang, Yong, 2023, In: Microbial Cell. 10, 11, p. 248-260 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    BayesMD: Flexible Biological Modeling for Motif Discovery

    Tang, M. E., Krogh, Anders & Winther, Ole, 2008, In: Journal of Computational Biology. 15, 10, p. 1347-63 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Beringian paleoecology inferred from permafrost-preserved fungal DNA

    Lydolph, M. C., Jacobsen, J., Arctander, P., Gilbert, M Thomas P, Gilichinsky, D. A., Hansen, Anders Johannes, Willerslev, Eske & Lange, L., 2005, In: Applied and Environmental Microbiology. 71, 2, p. 1012-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

    Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Biology, biodiversity and application potential of thermophilic viruses

    Uldahl, K. B. & Peng, Xu, 2013, Thermophilic Microbes in Environmental and Industrial Biotechnology: Biotechnology of Thermophiles. Satyanarayana, T., Littlechild, J. & Kawarabayasi, Y. (eds.). Springer, p. 271-304 34 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human rhabdomyosarcoma cell line

    Nielsen, F. C., Haselbacher, G., Christiansen, Jan, Lake, M., Gammeltoft, S. & Grønborg, M., 1993, In: Molecular and Cellular Endocrinology. 93, 1, p. 87-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Bird and plant companion species predict breeding and migrant habitats of the genus Oenanthe

    Pentzold, S., Pentzold, C. & Randler, C., 2011, In: Journal of Ecology and Field Biology. 34, 3, p. 287-293 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells

    Svenningsen, Mikkel Skjoldan, Veress, A., Harms, A., Mitarai, Namiko & Semsey, S., 15 Apr 2019, In: Scientific Reports. 9, 13 p., 6056.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

    Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis.

    Kojic, M., Zhou, Q., Lisby, Michael & Holloman, W. K., 2005, In: Molecular and Cellular Biology. 25, 7, p. 2547-57 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family

    Contursi, P., D'Ambrosio, K., Pirone, L., Pedone, E., Aucelli, T., She, Q., De Simone, G. & Bartolucci, S., 2011, In: Biochemical Journal. 435, 1, p. 157-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    COP9 signalosome: a provider of DNA building blocks

    Nielsen, Olaf, 15 Jul 2003, In: Current Biology. 13, 14, p. R565-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    CRI-SPA: a high-throughput method for systematic genetic editing of yeast libraries

    Cachera, P., Olsson, H., Coumou, H., Jensen, M. L., Sánchez, B., Strucko, T., Van den broek, M., Daran, J., Jensen, M., Sonnenschein, N., Lisby, Michael & Mortensen, U., 2023, In: Nucleic acids symposium series. 51, 17, 14 p., e91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    CRISPR History: Discovery, Characterization, and Prosperity

    Han, W. & She, Q., 2017, CRISPR in Animals and Animal Models. Torres-Ruiz, R. & Rodriguez-Perales, S. (eds.). Elsevier, p. 1-21 20 p. (Progress in Molecular Biology and Translational Science, Vol. 152).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    CRISPR adaptive immune systems of Archaea

    Vestergaard, G. A., Garrett, Roger Antony & Shah, S. A., 2014, In: R N A Biology. 11, 2, p. 157-168 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties

    Lillestøl, R. K., Shah, S. A., Brügger, K., Redder, P., Phan, Safir Hien, Christiansen, Jan & Garrett, Roger Antony, 2009, In: Molecular Microbiology. 72, 1, p. 259-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    CRISPR-Cas adaptive immune systems of the sulfolobales: unravelling their complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Erdmann, S., Guannan, L., Mousaei, M., León Sobrino, C., Peng, W., Islin, S. R., Deng, Ling, Vestergaard, G., Peng, Xu & She, Q., 2015, In: Life. 5, 1, p. 783-817 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

    Pinilla Redondo, Rafael, Russel, J., Mayo-Muñoz, D., Shah, S. A., Garrett, Roger Antony, Nesme, Joseph, Madsen, Jonas Stenløkke, Fineran, P. C. & Sørensen, Søren Johannes, 2022, In: Nucleic Acids Research. 50, 8, p. 4315-4328

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b

    He, F., Vestergaard, G. A., Peng, W., She, Q. & Peng, Xu, 2017, In: Nucleic Acids Research. 45, 4, p. 1902-1913 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    CRISPR-based immune systems of the Sulfolobales: complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Vestergaard, G. A., Deng, Ling, Guðbergsdóttir, S. R., Kenchappa, C. S., Erdmann, S. & She, Q., 2011, In: Biochemical Society Transactions. 39, 1, p. 51-57 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    CRISPR/Cas and CRISPR/Cmr immune systems of archaea

    Shah, S. A., Vestergaard, G. A. & Garrett, Roger Antony, 2012, Regulatory RNAs in prokaryotes. Springer, p. 163-181 19 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    CRISPR/Cas and Cmr modules, mobility and evolution of adaptive immune systems

    Shah, S. A. & Garrett, Roger Antony, 2011, In: Research in Microbiology. 162, 1, p. 27-38 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci

    Alkhnbashi, O. S., Costa, F., Shah, S. A., Garrett, Roger Antony, Saunders, S. J. & Backofen, R., 2014, In: Bioinformatics. 30, 17, p. i489-i496 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    CRP Interacts Specifically With Sxy to Activate Transcription in Escherichia coli

    Søndberg, E., Sinha, A. K., Gerdes, K. & Semsey, S., 2019, In: Frontiers in Microbiology. 10, 8 p., 2053.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B

    Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Catalase and NO CATALASE ACTIVITY1 promote autophagy-dependent cell death in Arabidopsis

    Hackenberg, T., Juul, T., Auzina, A., Gwizdz, S., Malolepszy, A., Van Der Kelen, K., Dam, S., Bressendorff, Simon, Lorentzen, A. M., Roepstorff, P., Nielsen, K. L., Jorgensen, J., Hofius, D., Van Breusegem, F., Petersen, Morten & Andersen, S. U., 2013, In: Plant Cell. 25, 11, p. 4616-4626 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cdc14 phosphatase: warning, no delay allowed for chromosome segregation!

    Machín, F., Quevedo Rodriguez, O., Ramos-Pérez, C. & García-Luis, J., 2016, In: Current Genetics. 62, 1, p. 7-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1.

    Kjaerulff, S., Andersen, N. R., Borup, M. T. & Nielsen, Olaf, 2007, In: Genes & Development. 21, 3, p. 347-59 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ

    Vischer, N. O. E., Verheul, J., Postma, M., van Saparoea, B. V. D. B., Galli, E., Natale, P., Gerdes, K., Luirink, J., Vollmer, W., Vicente, M. & den Blaauwen, T., 2015, In: Frontiers in Microbiology. 6, 18 p., 586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Cell biology of homologous recombination in yeast

    Eckert-Boulet, N. V., Rothstein, R. & Lisby, Michael, 2011, DNA recombination: methods and protocols. Tsubouchi, H. (ed.). Springer, p. 523-536 14 p. (Methods in Molecular Biology, Vol. 745).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  33. Published

    Cell biology of mitotic recombination

    Lisby, Michael & Rothstein, R., 2015, In: Cold Spring Harbor Perspectives in Biology. 7, 3, 23 p., a016535.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Cell cycle regulation of homologous recombination in Saccharomyces cerevisiae

    Mathiasen, D. P. & Lisby, Michael, 2014, In: F E M S Microbiology Reviews. 38, 2, p. 172-184 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Cell cycle-regulated centers of DNA double-strand break repair

    Lisby, Michael, Antúnez de Mayolo, A., Mortensen, U. H. & Rothstein, R., 10 Sep 2003, In: Cell Cycle. 2, 5, p. 479-83 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S.pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites

    Kjaerulff, S., Dooijes, D., Clevers, H., Nielsen, O. & Nielsen, Olaf, 1 Jul 1997, In: E M B O Journal. 16, 13, p. 4021-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cell growth of wall-free L-form bacteria is limited by oxidative damage

    Kawai, Y., Mercier, R., Wu, L. J., Dominguez Cuevas, P., Oshima, T. & Errington, J., 2015, In: Current Biology. 25, 12, p. 1613-1618 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cerebral dysautoregulation and the risk of ischemic events in occlusive carotid artery disease

    Reinhard, M., Gerds, Thomas Alexander, Grabiak, D., Zimmermann, P. R., Roth, M., Guschlbauer, B., Timmer, J., Czosnyka, M., Weiller, C. & Hetzel, A., 2008, In: Journal of Neurology. 255, 8, p. 1182-1189 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Chaperone role for proteins p618 and p892 in the extracellular tail development of Acidianus two-tailed virus

    Scheele, U., Erdmann, S., Ungewickell, E. J., Felisberto-Rodrigues, C., Ortiz-Lombardía, M. & Garrett, Roger Antony, 2011, In: Journal of Virology. 85, 10, p. 4812-4821 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Characterising the CRISPR immune system in Archaea using genome sequence analysis

    Shah, S. A., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 219 p.

    Research output: Book/ReportPh.D. thesisResearch

  41. Published

    Characterization and transcriptional analysis of two gene clusters for type IV secretion machinery in Wolbachia of Armadillidium vulgare

    Félix, C., Pichon, S., Braquart-Varnier, C., Braig, H., Chen, L., Garrett, Roger Antony, Martin, G. & Grève, P., 2008, In: Research in Microbiology. 159, 6, p. 481-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Characterization of a novel type III CRISPR-Cas effector provides new insights into the allosteric activation and suppression of the Cas10 DNase

    Lin, Jinzhong, Feng, M., Zhang, H. & She, Q., 2020, In: Cell Discovery. 6, 16 p., 29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Characterization of an archaeal virus replication initiator protein and first insights into virus assembly of spindle-shaped virus SMV1

    Zhang, W., 2021, Department of Biology, Faculty of Science, University of Copenhagen. 140 p.

    Research output: Book/ReportPh.D. thesisResearch

  44. Published

    Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation

    Petersen, J., Weilguny, D., Egel, Richard, Nielsen, O. & Nielsen, Olaf, 1 Jul 1995, In: Molecular and Cellular Biology. 15, 7, p. 3697-707 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Characterization of pMC11, a plasmid with dual origins of replication isolated from Lactobacillus casei MCJ and construction of shuttle vectors with each replicon

    Chen, Z., Lin, J., Ma, C., Zhao, S., She, Q. & Liang, Y., 2014, In: Applied Microbiology and Biotechnology. 98, 13, p. 5977-5989 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Characterization of three genes in the dam-containing operon of Escherichia coli

    Lyngstadaas, A., Løbner-Olesen, Anders & Boye, E., 10 Jun 1995, In: Molecular General Genetics. 247, 5, p. 546-54 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Characterizing leader sequences of CRISPR loci

    Alkhnbashi, O., Shah, S. A., Garrett, Roger Antony, Saunders, S. J., Costa, F. & Backofen, R., 2016, In: Bioinformatics. 32, 17, p. i576-i585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

    Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Chitin and stress induced protein kinase activation

    Kenchappa, C. S., Azevedo da Silva, R., Bressendorff, Simon, Stanimirovic, S., Olsen, J. V., Petersen, Morten & Mundy, J., 2017, Plant pattern recognition receptors: methods and protocols. Shan, L. & He, P. (eds.). Springer, p. 185-194 10 p. (Methods in Molecular Biology, Vol. 1578).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. Published

    Chitin-induced responses in the moss Physcomitrella patens

    Bressendorff, Simon, Rasmussen, M. W., Petersen, Morten & Mundy, J., 2017, Plant pattern recognition receptors: methods and protocols. Shan, L. & He, P. (eds.). Springer, p. 317-324 8 p. (Methods in Molecular Biology, Vol. 1578).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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