Imaging of DNA Ultrafine Bridges in Budding Yeast
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
DNA ultrafine bridges (UFBs) are a type of chromatin-free DNA bridges that connect sister chromatids in anaphase and pose a threat to genome stability. However, little is known about the origin of these structures, and how they are sensed and resolved by the cell. In this chapter, we review tools and methods for studying UFBs by fluorescence microscopy including chemical and genetic approaches to induce UFBs in the model organism Saccharomyces cerevisiae.
Original language | English |
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Title of host publication | Genome Instability : Methods and Protocols |
Editors | Marco Muzi-Falconi, Grant W. Brown |
Number of pages | 11 |
Publisher | Humana Press |
Publication date | 2018 |
Pages | 483-493 |
ISBN (Print) | 978-1-4939-7305-7 |
ISBN (Electronic) | 978-1-4939-7306-4 |
DOIs | |
Publication status | Published - 2018 |
Series | Methods in Molecular Biology |
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Volume | 1672 |
ISSN | 1064-3745 |
ID: 196437518