Isolation of the neuropeptide less than Glu-Trp-Leu-Lys-Gly-Arg-Phe-NH2 (Pol-RFamide II) from the hydromedusa Polyorchis penicillatus

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Using a radioimmunoassay for the sequence Arg-Phe-NH2 (RFamide), we have isolated the peptide less than Glu-Trp-Leu-Lys-Gly-Arg-Phe-NH2 (Pol-RFamide II) from acetic acid extracts of the hydromedusa Polyorchis penicillatus. This peptide is a neuropeptide and constitutes a peptide family together with less than Glu-Leu-Leu-Gly-Gly-Arg-Phe-NH2 (Pol-RFamide I), the first neuropeptide isolated from Polyorchis, and less than Glu-Gly-Arg-Phe-NH2 (Antho-RFamide), a neuropeptide isolated from sea anemones and sea pansies.
Original languageEnglish
JournalBiochemical and Biophysical Research Communications
Volume183
Issue number2
Pages (from-to)375-82
Number of pages8
ISSN0006-291X
Publication statusPublished - 16 Mar 1992

    Research areas

  • Amino Acid Sequence, Animals, Gas Chromatography-Mass Spectrometry, Molecular Sequence Data, Neuropeptides, Oligopeptides, Pyrrolidonecarboxylic Acid, Radioimmunoassay, Scyphozoa, Sequence Homology, Nucleic Acid

ID: 33514089