Functional Genomics

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  1. Published

    Isolation and characterization of the first Xylanolytic hyperthermophilic euryarchaeon Thermococcus sp strain 2319x1 and its unusual multidomain glycosidase

    Gavrilov, S. N., Stracke, C., Jensen, K., Menzel, P., Kallnik, V., Slesarev, A., Sokolova, T., Zayulina, K., Bräsen, C., Bonch-Osmolovskaya, E. A., Peng, Xu, Kublanov, I. V. & Siebers, B., 2016, In: Frontiers in Microbiology. 7, 17 p., 552.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Microbiology: pumping persisters

    Gerdes, K. & Semsey, S., 2016, In: Nature. 534, 7605, p. 41-42 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  3. Published

    Hypothesis: type I toxin - antitoxin genes enter the persistence field-a feedback mechanism explaining membrane homoeostasis

    Gerdes, K., 2016, In: Royal Society of London. Philosophical Transactions B. Biological Sciences. 371, 1707, 9 p., 20160189.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability

    Germann, S. M., Schramke, V., Pedersen, R. T., Gallina, I., Eckert-Boulet, N., Østergaard, Vibe Hallundbæk & Lisby, Michael, 2014, In: Journal of Cell Biology. 204, 1, p. 45-59 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination

    Germann, S. M., Østergaard, Vibe Hallundbæk, Haas, C., Salis, P., Motegi, A. & Lisby, Michael, 2011, In: D N A Repair. 10, 2, p. 210-224 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Dpb11/TopBP1 contributes to genomicstability via homologous recombinationand checkpoint signaling

    Germann, S. M., 2009, Biologisk Institut: Museum Tusculanum. 175 p.

    Research output: Book/Report › Ph.D. thesis › Research

  7. Published

    Thresholds for clinical importance were defined for the European Organisation for Research and Treatment of Cancer Computer Adaptive Testing Core-an adaptive measure of core quality of life domains in oncology clinical practice and research

    Giesinger, J. M., Loth, F. L. C., Aaronson, N. K., Arraras, J. I., Caocci, G., Efficace, F., Grønvold, Mogens, van Leeuwen, M., Petersen, Morten, Ramage, J., Tomaszewski, K. A., Young, T., Holzner, B. & EORTC Quality of Life Group, E. Q. O. L. G., 2020, In: Journal of Clinical Epidemiology. 117, p. 117-125 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Thresholds for clinical importance were established to improve interpretation of the EORTC QLQ-C30 in clinical practice and research

    Giesinger, J. M., Loth, F. L. C., Aaronson, N. K., Arraras, J. I., Caocci, G., Efficace, F., Grønvold, Mogens, van Leeuwen, M., Petersen, Morten, Ramage, J., Tomaszewski, K. A., Young, T., Holzner, B. & EORTC Quality of Life Group, E. Q. O. L. G., 2020, In: Journal of Clinical Epidemiology. 118, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    An improved PCR method for endogenous DNA retrieval in contaminated Neandertal samples based on the usage of blocking primers

    Gigli, E., Rasmussen, M., Civit, S., Rosas, A., de la Rasilla, M., Fortea, J., Gilbert, M Thomas P, Willerslev, Eske & Lalueza-Fox, C., 2009, In: Journal of Archaeological Science. 36, p. 2676-2679

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Response to Comment by Poinar et al. on "DNA from Pre-Clovis Human Coprolites in Oregon, North America"

    Gilbert, M Thomas P, Jenkins, D., Higham, T., Rasmussen, M., Malmstrom, H., Svensson, E., Sanchez, J., Cummings, L., Yohe, I. R., Hofreiter, M., Götherström, A. & Willerslev, Eske, 2009, In: Science. 325, 5937, p. 148 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  11. Published

    FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Burton, C. M., Rossen, K., Skovgaard, G. L., Ryder, L. P. & Ralfkiaer, E., 2007, In: Leukemia. 21, 12, p. 2512-2518 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    FOXP3 positive regulatory T-cells in cutaneous T-cell lymphomas

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels & Ralfkiaer, E., 2008, In: Virchows Archiv. 452, Suppl. 1, p. S4-S4

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations

    Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Hother, C., Henrik-Nielsen, R., Gniadecki, R. & Ralfkiaer, E., 2008, In: European Journal of Haematology. 80, 6, p. 483-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A promoter within the E6 ORF of human papillomavirus type 16 contributes to the expression of the E7 oncoprotein from a monocistronic mRNA

    Glahder, J. H., Hansen, C. N., Vinther, Jeppe, Madsen, B. S. & Norrild, B., 2003, In: Journal of General Virology. 84, Pt 12, p. 3429-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effects of LPS Composition in Escherichia coli on Antibacterial Activity and Bacterial Uptake of Antisense Peptide-PNA Conjugates

    Goltermann, Lise, Zhang, Meiqin, Ebbensgaard, Anna Elisabeth, Fiodorovaite, M., Yavari, Niloofar, Løbner-Olesen, Anders & Nielsen, Peter E., 2022, In: Frontiers in Microbiology. 13, 877377.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Comparative genomics for non-O1/O139 Vibrio cholerae isolates recovered from the Yangtze River Estuary versus V. cholerae representative isolates from serogroup O1

    Gong, L., Yu, P., Zheng, H., Gu, W., He, W., Tang, Y., Wang, Y., Dong, Y., Peng, Xu, She, Q., Xie, L. & Chen, L., 2019, In: Molecular Genetics and Genomics. 294, 2, p. 417-430

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Getting the best out of long-wavelength X-rays: de novo chlorine/sulfur SAD phasing of a structural protein from ATV

    Goulet, A., Vestergaard, G. A., Felisberto-Rodrigues, C., Campanacci, V., Garrett, Roger Antony, Cambillau, C. & Ortiz-Lombardía, M., 2010, In: Acta Crystallographica. Section D: Biological Crystallography. 66, Pt 3, p. 304-308 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV)

    Goulet, A., Spinelli, S., Campanacci, V., Porciero, S., Blangy, S., Garrett, Roger Antony, van Tilbeurgh, H., Leulliot, N., Basta, T., Prangishvili, D. & Cambillau, C., 2006, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 62, Pt 9, p. 884-886 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Receptor-like kinase complexes in plant innate immunity

    Greeff, M. C., Roux, M. E., Mundy, J. & Petersen, Morten, 2012, In: Frontiers in Plant Science. 3, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Suppressing autoimmunity in Arabidopsis thaliana with dominant negative immune receptors

    Greeff, M. C., 2014, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  21. Published

    MicroRNA-145 targets YES and STAT1 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Proteins involved in attack and defence in Zygomycete-aphid interactions

    Grell, M. N., Jensen, Annette Bruun & Lange, L., 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  23. Published

    Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus

    Gresham, D., Usaite, R., Germann, S. M., Lisby, Michael, Botstein, D. & Regenberg, Birgitte, 2010, In: Proceedings of the National Academy of Science of the United States of America. 107, 43, p. 18551-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genomic comparison of archaeal conjugative plasmids from Sulfolobus

    Greve, B., Jensen, S., Brügger, K., Zillig, W. & Garrett, Roger Antony, 2004, In: Archaea. Vol. 1., p. 231-239

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Basal level of ppGpp coordinates Escherichia coli cell heterogeneity and ampicillin resistance and persistence

    Grucela, Paulina Katarzyna & Zhang, Yong, 2023, In: Microbial Cell. 10, 11, p. 248-260 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Ribose 5-phosphate: the key metabolite bridging the metabolisms of nucleotides and amino acids during stringent response in Escherichia coli?

    Grucela, Paulina Katarzyna, Fuhrer, T., Sauer, U., Chao, Y. & Zhang, Yong, 2023, In: Microbial Cell. 10, 7, p. 141-144

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Chromosome-scale genomes provide new insights into subspecies divergence and evolutionary characteristics of the giant panda

    Guang, X., Lan, T., Wan, Q. H., Huang, Y., Li, H., Zhang, M., Li, R., Zhang, Z., Lei, Y., Zhang, L., Zhang, H., Li, D., Li, X., Li, H., Xu, Y., Qiao, M., Wu, D., Tang, K., Zhao, P., Lin, J-Q. & 11 others, Sahu, S. K., Liang, Q., Jiang, W., Zhang, D., Xu, X., Liu, X., Lisby, Michael, Yang, H., Kristiansen, Karsten, Liu, Huan & Fang, S., 2021, In: Science Bulletin. 66, 19, p. 2002-2013 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugated Sulfolobus species

    Guannan, L., She, Q. & Garrett, Roger Antony, 2016, In: Nucleic Acids Research. 44, 9, p. 4233-4242 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Studying Extrachromosomal Genetic Elements in Sulfolobus

    Guannan, L., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 85 p.

    Research output: Book/Report › Ph.D. thesis › Research

  30. Published

    Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda

    Gui, F., Lan, T., Zhao, Y., Guo, W., Dong, Y., Fang, D., Liu, H., Li, H., Wang, H., Hao, R., Cheng, X., Li, Y., Yang, P., Sahu, S. K., Chen, Y., Cheng, L., He, S., Liu, P., Fan, G., Lu, H. & 24 others, Hu, G., Dong, W., Chen, B., Jiang, Y., Zhang, Y., Xu, H., Lin, F., Slippers, B., Postma, A., Jackson, M., Abate, B. A., Tesfaye, K., Demie, A. L., Bayeleygne, M. D., Degefu, D. T., Chen, F., Kuria, P. K., Kinyua, Z. M., Liu, T., Yang, H., Huang, F., Liu, X., Sheng, J. & Kang, L., 2022, In: Protein & Cell (Print). 13, 7, p. 513-531 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing

    Gummesson, Bertil, Shah, S. A., Borum, A. S., Fessler, M., Mitarai, Namiko, Sørensen, Michael Askvad & Svenningsen, Sine Lo, 2020, In: Frontiers in Genetics. 11, 17 p., 144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Genome Analyses of Icelandic Strains of Sulfolobus islandicus, Model Organisms for Genetic and Virus-Host Interaction Studies

    Guo, L., Brügger, K., Liu, C., Shah, S. A., Zheng, H., Zhu, Y., Wang, S., Lillestøl, R. K., Chen, L., Frank, J., Prangishvili, D., Paulin, L., She, Q., Huang, L. & Garrett, Roger Antony, 1 Apr 2011, In: Journal of Bacteriology. 193, 7, p. 1672-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Investigation of the Sulfolobus islandicus III-B Cmr-α CRISPR-Cas system and SMV1 anti-CRISPR activity

    Guo, T., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  34. Published

    Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus

    Guo, T., Han, W. & She, Q., 2019, In: RNA Biology. 16, 4, p. 549-556 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system

    Guo, T., Zheng, F., Zeng, Z., Yang, Y., Li, Q., She, Q. & Han, W., 2019, In: RNA Biology. 16, 10, p. 1513-1520

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Chloranthus genome provides insights into the early diversification of angiosperms

    Guo, X., Fang, D., Sahu, S. K., Yang, S., Guang, X., Folk, R., Smith, S. A., Chanderbali, A. S., Chen, S., Liu, M., Yang, T., Zhang, S., Liu, X., Xu, X., Soltis, P. S., Soltis, D. E. & Liu, Huan, 2021, In: Nature Communications. 12, 14 p., 6930.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities

    Guo, Y., Kragelund, Birthe Brandt, White, M. F. & Peng, Xu, 2015, In: Journal of Molecular Biology. 427, 12, p. 2179-2191 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers

    Guðbergsdóttir, S. R., Deng, L., Chen, Z., Jensen, J. V. K., Jensen, L. R., She, Q. & Garrett, Roger Antony, 2011, In: Molecular Microbiology. 79, 1, p. 35-49 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex

    Géli, V. & Lisby, Michael, 2015, In: BioEssays. 37, 12, p. 1287-1292 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Catalase and NO CATALASE ACTIVITY1 promote autophagy-dependent cell death in Arabidopsis

    Hackenberg, T., Juul, T., Auzina, A., Gwizdz, S., Malolepszy, A., Van Der Kelen, K., Dam, S., Bressendorff, Simon, Lorentzen, A. M., Roepstorff, P., Nielsen, K. L., Jorgensen, J., Hofius, D., Van Breusegem, F., Petersen, Morten & Andersen, S. U., 2013, In: Plant Cell. 25, 11, p. 4616-4626 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module

    Hadzi, S., Garcia-Pino, A., Gerdes, K., Lah, J. & Loris, R., 2015, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 71, 2, p. 226-233 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism

    Hadži, S., Garcia-Pino, A., Haesaerts, S., Jurėnas, D., Gerdes, K., Lah, J. & Loris, R., 5 May 2017, In: Nucleic Acids Research. 45, 8, p. 4972-4983 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Ancient DNA reveals late survival of mammoth and horse in interior Alaska

    Haile, James Seymour, Froese, D. G., Macphee, R. D. E., Roberts, R. G., Arnold, L. J., Reyes, A. V., Rasmussen, M., Nielsen, Rasmus, Brook, B. W., Robinson, S., Demuro, M., Gilbert, M Thomas P, Munch, K., Austin, J. J., Cooper, A., Barnes, I., Möller, P. & Willerslev, Eske, 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 52, p. 22352-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Posttranscriptional crossregulation between Drosha and DGCR8

    Han, J., Pedersen, Jakob Skou, Kwon, S. C., Belair, C. D., Kim, Y., Yeom, K., Yang, W., Haussler, D., Blelloch, R. & Kim, V. N., 2009, In: Cell. 136, 1, p. 75-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Chromosome-scale assembly and whole-genome sequencing of 266 giant panda roundworms provide insights into their evolution, adaptation and potential drug targets

    Han, L., Lan, T., Li, D., Li, H., Deng, L., Peng, Z., He, S., Zhou, Y., Han, R., Li, L., Lu, Y., Lu, H., Wang, Q., Yang, S., Zhu, Y., Huang, Y., Cheng, X., Yu, J., Wang, Y., Sun, H. & 8 others, Chai, H., Yang, H., Xu, X., Lisby, Michael, Liu, Q., Kristiansen, Karsten, Liu, Huan & Hou, Z., 2022, In: Molecular Ecology Resources. 22, 2, p. 768-785 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction

    Han, W., Li, Y., Deng, Ling, Feng, M., Peng, W., Hallstrøm, S., Zhang, J., Peng, N., Liang, Y. X., White, M. F. & She, Q., 2017, In: Nucleic Acids Research. 45, 4, p. 1983–1993 11 p., gkw1274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Nanobiomotors of archaeal DNA repair machineries: current research status and application potential

    Han, W., Shen, Y. & She, Q., 2014, In: Cell & Bioscience. 4, 32, 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    CRISPR History: Discovery, Characterization, and Prosperity

    Han, W. & She, Q., 2017, CRISPR in Animals and Animal Models. Torres-Ruiz, R. & Rodriguez-Perales, S. (eds.). Elsevier, p. 1-21 20 p. (Progress in Molecular Biology and Translational Science, Vol. 152).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  49. Published

    NQO-induced DNA-less cell formation is associated with chromatin protein degradation and dependent on A0A1-ATPase in Sulfolobus

    Han, W., Xu, Y., Feng, X., Liang, Y. X., Huang, L., Shen, Y. & She, Q., 14 Aug 2017, In: Frontiers in Microbiology. 8, 12 p., 1480.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Reverse gyrase functions in genome integrity maintenance by protecting DNA breaks in vivo

    Han, W., Feng, X. & She, Q., Jul 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1340.

    Research output: Contribution to journal › Journal article › Research › peer-review

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