Functional Genomics

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  1. Published

    Myocardial perfusion defects and the left ventricular ejection fraction disclosed by scintigraphy in patients with primary hyperparathyroidism

    Ogard, C. G., Søndergaard, S. B., drb459, drb459, Jakobsen, H., Nielsen, S. L. & drb459, drb459, Jul 2005, In: World Journal of Surgery. 29, 7, p. 914-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Dissecting the cell-killing mechanism of the topoisomerase II-targeting drug ICRF-193

    Østergaard, Vibe Hallundbæk, Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28100-28105 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair

    Østergaard, Vibe Hallundbæk, Langevin, F., Kuiken, H. J., Pace, P., Niedzwiedz, W., Simpson, L. J., Ohzeki, M., Takata, M., Sale, J. E. & Patel, K. J., 14 Dec 2007, In: Molecular Cell. 28, 5, p. 798-809 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Hindering the strand passage reaction of human topoisomerase IIα without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp

    Østergaard, Vibe Hallundbæk, Giangiacomo, L., Bjergbaek, L., Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28093-28099 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The Transducer Domain Is Important for Clamp Operation in Human DNA Topoisomerase IIα

    Østergaard, Vibe Hallundbæk, Bjergbaek, L., Skouboe, C., Giangiacomo, L., Knudsen, B. R. & Andersen, A. H., 16 Jan 2004, In: Journal of Biological Chemistry. 279, 3, p. 1684-1691 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

    Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, Anders, Thulstrup, Peter Waaben, Sanderson, J. M. & Hansen, Paul Robert, 2016, In: ACS Medicinal Chemistry Letters. 7, 8, p. 741-745 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Nucleation and spreading of a heterochromatic domain in fission yeast

    Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Nucleotide sequence and PCR-amplification of a polymorphic MboI site in human DNA marker D4S95 linked to the Huntington disease locus.

    Nørremølle, Anne, Sørensen, S. A. & Arctander, P., 1992, In: Clinical Genetics. 42, p. 210-211 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development

    Næsted, H., Holm, A., Jenkins, T., Nielsen, H. B., Harris, C. A., Beale, M. H., Andersen, M., Mant, A., Scheller, H. V., Camara, B., Mattsson, O. & Mundy, J., 2004, In: Journal of Cell Science. 117, 20, p. 4807-18 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing

    Nygaard, S., Jacobsen, A., Lindow, M., Eriksen, J., Balslev, E., Flyger, H., Tolstrup, N., Moller, S., Krogh, Anders & Litman, T., 2009, In: B M C Medical Genomics. 2, 1, p. 35

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Investigating non-coding genome content using high-throughput sequencing data

    Nygaard, S., 2009, Biologisk Institut: Museum Tusculanum. 34 p.

    Research output: Book/Report › Ph.D. thesis › Research

  13. Published

    Mitochondrial DNA diversity and population structure of a forest-dependent rodent, Praomys taitae (Rodentia: Muridae) Heller 1911, in the fragmented forest patches of Taita Hills, Kenya

    Nyakaana, S., Tumusiime, C., Oguge, N., Siegismund, Hans Redlef, Arctander, P. & Muwanika, V., 2008, In: South African Journal of Science. 104, 11/12, p. 499-504

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Population structure of the African savannah elephant inferred from mitochondrial control region sequences and nuclear microsatellite loci

    Nyakaana, S., Arctander, P. & Siegismund, Hans Redlef, 2002, In: Heredity. 89, 2, p. 90-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The role of C/EBPa in PD-1+ CD4+ T cells & modulation of RNR activity prolongs survival of mice with AML

    Norrie, I. C., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.

    Research output: Book/Report › Ph.D. thesis › Research

  17. Published

    Nucleotide sequence of pOLA52: a conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux

    Norman, A., Hansen, Lars Hestbjerg, She, Q. & Sørensen, Søren Johannes, 2008, In: Plasmid. 60, 1, p. 59-74 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

    Nielsen, S. V., Turnbull, K. J., Roghanian, Mohammad, Bærentsen, R., Semanjski, M., Brodersen, D. E., Macek, B. & Gerdes, K., 2019, In: mBio. 10, 3, 16 p., e-01138-19.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.

    Nielsen, Olaf & Løbner-Olesen, Anders, 2008, In: EMBO Reports. 9, 2, p. 151-156 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Synchronization of S phase in Schizosaccharomyces pombe cells by transient exposure to M-factor pheromone

    Nielsen, Olaf, 2016, In: Cold Spring Harbor Protocols. 2016, 9, p. 768-772 5 p.

    Research output: Contribution to journal › Journal article › Research

  21. Published

    Fission yeast goes synthetic.

    Nielsen, Olaf, 2007, In: Nature Methods. 4, 10, p. 777-8 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    COP9 signalosome: a provider of DNA building blocks

    Nielsen, Olaf, 15 Jul 2003, In: Current Biology. 13, 14, p. R565-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The pat1 protein kinase controls transcription of the mating-type genes in fission yeast

    Nielsen, O., Egel, Richard & Nielsen, Olaf, 1 May 1990, In: E M B O Journal. 9, 5, p. 1401-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Pheromone communication in the fission yeast Schizosaccharomyces pombe

    Nielsen, O., Davey, W. J. & Nielsen, Olaf, 1 Apr 1995, In: Seminars in Cell Biology. 6, 2, p. 95-104 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The ras1 function of Schizosaccharomyces pombe mediates pheromone-induced transcription

    Nielsen, O., Davey, W. J., Egel, Richard & Nielsen, Olaf, 1 Apr 1992, In: E M B O Journal. 11, 4, p. 1391-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Mapping the double-strand breaks at the mating-type locus in fission yeast by genomic sequencing

    Nielsen, O., Egel, Richard & Nielsen, Olaf, 1 Jan 1989, In: E M B O Journal. 8, 1, p. 269-76 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The Schizosaccharomyces pombe map1 gene encodes an SRF/MCM1-related protein required for P-cell specific gene expression

    Nielsen, O., Friis, T., Kjaerulff, S. & Nielsen, Olaf, 13 Dec 1996, In: Molecular and General Genetics MGG. 253, 3, p. 387-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Signal transduction during mating and meiosis in S. pombe

    Nielsen, O. & Nielsen, Olaf, 1 Feb 1993, In: Trends in Cell Biology. 3, 2, p. 60-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

    Nielsen, M., Kaestel, C. G., Eriksen, K. W., Woetmann, Anders , Stokkedal, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Odum, N., 1999, In: Leukemia. 13, 5, p. 735-8 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Genetic diversity and phylogenetic analysis of the attachment glycoprotein of phocine distemper viruses of the 2002 and 1988 epizootics

    Nielsen, L., Arctander, P., Jensen, T. H., Dietz, Hans Henrik, Hammer, A. S., Banyard, A., Barrett, T. & Blixenkrone-Møller, M., 2009, In: Virus Research. 144, 1-2, p. 323-328 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region

    Nielsen, I. S., Nielsen, Olaf, Murray, J. M. & Thon, Genevieve, 1 Aug 2002, In: Eukaryotic Cell (Online Edition). 1, 4, p. 613-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    A Flp-nick system to study repair of a single protein-bound nick in vivo

    Nielsen, I., Bentsen, I. B., Lisby, Michael, Hansen, S., Mundbjerg, K., Andersen, A. H. & Bjergbaek, L., 2009, In: Nature Methods. 6, 10, p. 753-757 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    A conformational switch in the DiGIR1 ribozyme involved in release and folding of the downstream I-DirI mRNA

    Nielsen, Henrik, Einvik, C., Lentz, T. E., Hedegaard, M. M. & Johansen, S. D., 2009, In: RNA: A publication of the RNA Society. 15, 5, p. 958-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Aspects of ribonucleotide reductase regulation and genome stability: a study of human ribonucleotide reductase ssing fission yeast as a model

    Nielsen, H. B. N., 2014, Department of Biology, Faculty of Science, University of Copenhagen. 149 p.

    Research output: Book/Report › Ph.D. thesis › Research

  35. Published

    Endonucleolysis in the turnover of insulin-like growth factor II mRNA

    Nielsen, F. C. & Christiansen, Jan, 1992, In: Journal of Biological Chemistry. 267, 27, p. 19404-11 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Insulin-like growth factor II mRNA, peptides, and receptors in a thoracopulmonary malignant small round cell tumor

    Nielsen, F. C., Orskov, C., Haselbacher, G., Ramlau, J., Christiansen, Jan, Schmiegelow, Kjeld & Rehfeld, Jens Frederik, 1994, In: Cancer. 73, 4, p. 1312-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human rhabdomyosarcoma cell line

    Nielsen, F. C., Haselbacher, G., Christiansen, Jan, Lake, M., Gammeltoft, S. & Grønborg, M., 1993, In: Molecular and Cellular Endocrinology. 93, 1, p. 87-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Establishment of heterochromatin in domain-size-dependent bursts

    Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The transcription factor Atf1 lowers the transition barrier for nucleosome-mediated establishment of heterochromatin

    Nickels, Jan Fabio, Della-Rosa, M. E., Miguelez Goyeneche, I., Charlton, Sebastian Jespersen, Sneppen, Kim & Thon, Genevieve, 2022, In: Cell Reports. 39, 7, 17 p., 110828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A

    Møller, M. B., Kania, Per, Ino, Y., Gerdes, Anne-Marie Axø, Nielsen, Olaf, Louis, D. N., Skjødt, K. & Pedersen, N. T., May 2000, In: Leukemia. 14, 5, p. 898-904 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    RNAi screening for characterisation of ER-associated degradation pathways in mammalian cells

    Månsson, M. D. J., 2013, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  43. Published

    Population genetic structure of the common warthog (Phacochoerus africanus) in Uganda: evidence for a strong philopatry among warthogs and social structure breakdown in a disturbed population

    Muwanka, V. B., Nyakaana, S., Siegismund, Hans Redlef & Arctander, P., 2007, In: African Journal of Ecology. 45, 1, p. 22-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Large Intronic Deletion of the Fragile Site Gene PRKN Dramatically Lowers Its Fragility Without Impacting Gene Expression

    Munk, S. H. N., Voutsinos, Vasileios & Østergaard, Vibe Hallundbæk, 2021, In: Frontiers in Genetics. 12, 9 p., 695172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Top2 and Sgs1-Top3 act redundantly to ensure rDNA replication termination

    Mundbjerg, K., Jørgensen, S. W., Fredsøe, J. C., Nielsen, I., Pedersen, J. M., Bentsen, I. B., Lisby, Michael, Bjergbaek, L. & Andersen, A. H., 2015, In: P L o S Genetics. 11, 12, 24 p., e1005697.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Comparative Effectiveness of Low-Volume Time-Efficient Resistance Training Versus Endurance Training in Patients With Heart Failure

    Munch, G. W., Rosenmeier, J. B., Petersen, Morten, Rinnov, A. R., Iepsen, U. W., Pedersen, Bente Klarlund & Mortensen, S. P., 2018, In: Journal of Cardiopulmonary Rehabilitation and Prevention. 38, 3, p. 175-181 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis

    Munch, D., Rodriguez, E., Bressendorff, Simon, Park, O. K., Hofius, D. & Petersen, Morten, 2014, In: Autophagy. 10, 9, p. 1579-1587 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Autophagy and Retromer Components in Plant Innate Immunity

    Munch, D., 2014, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  49. Published

    Retromer contributes to immunity-associated cell death in Arabidopsis

    Munch, D., Teh, O., Malinovsky, F. G., Liu, Q., Vetukuri, R. R., El Kasmi, F., Brodersen, Peter, Hara-Nishimura, I., Dangl, J. L., Petersen, Morten, Mundy, J. & Hofius, D., 2015, In: Plant Cell. 27, 2, p. 463-479 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Major and minor crRNA annealing sites facilitate low stringency DNA protospacer binding prior to Type I-A CRISPR-Cas interference in Sulfolobus

    Mousaei, M., Deng, Ling, She, Q. & Garrett, Roger Antony, 2016, In: R N A Biology. 13, 11, p. 1166-1173 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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