Functional Genomics

  1. Published

    Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

    Birney, E., Stamatoyannopoulos, J. A., Dutta, A., Guigó, R., Gingeras, T. R., Margulies, E. H., Weng, Z., Snyder, M., Dermitzakis, E. T., Thurman, R. E., Kuehn, M. S., Taylor, C. M., Neph, S., Koch, C. M., Asthana, S., Malhotra, A., Adzhubei, I., Greenbaum, J. A., Andrews, R. M., Flicek, P. & 36 others, Boyle, P. J., Cao, H., Carter, N. P., Clelland, G. K., Davis, S., Day, N., Dhami, P., Dillon, S. C., Dorschner, M. O., Fiegler, H., Giresi, P. G., Goldy, J., Hawrylycz, M., Haydock, A., Humbert, R., James, K. D., Johnson, B. E., Johnson, E. M., Frum, T. T., Rosenzweig, E. R., Karnani, N., Lee, K., Lefebvre, G. C., Navas, P. A., Neri, F., Parker, S. C. J., Sabo, P. J., Sandstrom, R., Sandelin, Albin Gustav, Pedersen, J. S., ENCODE Project Consortium, E. P. C., NISC Comparative Sequencing Program, N. C. S. P., Baylor College of Medicine Human Genome Sequencing Center, B. C. O. M. H. G. S. C., Washington University Genome Sequencing Center, W. U. G. S. C., Broad Institute, B. I. & Children's Hospital Oakland Research Institute, C. H. O. R. I., 2007, In: Nature. 447, 7146, p. 799-816 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response

    Bisiak, F., Chrenková, A., Zhang, S., Pedersen, J. N., Otzen, D. E., ZHANG, YONG & Brodersen, D. E., 2022, In: Journal of Biological Chemistry. 298, 7, 16 p., 102142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Viruses in acidic geothermal environments of the Kamchatka Peninsula

    Bize, A., Peng, Xu, Prokofeva, M., Maclellan, K., Lucas, S., Forterre, P., Garrett, Roger Antony, Bonch-Osmolovskaya, E. A. & Prangishvili, D., 2008, In: Research in Microbiology. 159, 5, p. 358-66 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe

    Bjerling, P., Ekwall, K., Egel, Richard & Thon, Genevieve, 2004, In: Nucleic Acids Research. 32, 15, p. 4421-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Suppressors of Hyperinitiation in Escherichia coli Couple DNA Replication to Precursor Biosynthesis and Energy Metabolism

    Bjørn, L., 2015, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  6. Published

    Lack of the RNA chaperone Hfq attenuates pathogenicity of several Escherichia coli pathotypes towards Caenorhabditis elegans

    Bojer, M. S., Jakobsen, H., Struve, C., Krogfelt, K. A. & Løbner-Olesen, Anders, 2012, In: Microbes and Infection. 14, 12, p. 1034-1039 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A Unified Resource for Tracking Anti-CRISPR Names

    Bondy-Denomy, J., Davidson, A. R., Doudna, J. A., Fineran, P. C., Maxwell, K. L., Moineau, S., Peng, Xu, Sontheimer, E. J. & Wiedenheft, B., 2018, In: CRISPR Journal. 1, 5, p. 304-305

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Control of specific gene expression by gibberellin and brassinosteroid

    Bouquin, T., Meier, C., Foster, R., Nielsen, Mads Eggert & Mundy, J., 2001, In: Plant Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The Arabidopsis lue1 mutant defines a katanin p60 ortholog involved in hormonal control of microtubule orientation during cell growth.

    Bouquin, T., Mattsson, O., Naested, H., Foster, R. & Mundy, J., 2003, In: Journal of Cell Science. 116, Pt 5, p. 791-801 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II

    Bourbon, H. M., Aguilera, A., Ansari, A. Z., Asturias, F. J., Berk, A. J., Bjorklund, S., Blackwell, T. K., Borggrefe, T., Carey, M., Carlson, M., Conaway, J. W., Conaway, R. C., Emmons, S. W., Fondell, J. D., Freedman, L. P., Fukasawa, T., Gustafsson, C. M., Han, M., He, X., Herman, P. K. & 27 others, Hinnebusch, A. G., Holmberg, Steen, Holstege, F. C., Jaehning, J. A., Kim, Y., Kuras, L., Leutz, A., Lis, J. T., Meisterernest, M., Naar, A. M., Nasmyth, K., Parvin, J. D., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, P. W., Stillman, D. J., Strich, R., Struhl, K., Svejstrup, J. Q., Tuck, S., Winston, F., Roeder, R. G. & Kornberg, R. D., 2004, In: Molecular Cell. 14, 5, p. 553-557

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Bacterial growth control studied by flow cytometry

    Boye, E. & Løbner-Olesen, Anders, 1 Feb 1991, In: Research in Microbiology. 142, 2-3, p. 131-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Flow cytometry: illuminating microbiology

    Boye, E. & Løbner-Olesen, Anders, Feb 1990, In: The New Biologist. 2, 2, p. 119-25 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Timing of chromosomal replication in Escherichia coli

    Boye, E., Løbner-Olesen, Anders & Skarstad, K., 20 Dec 1988, In: B B A - Reviews on Cancer. 951, 2-3, p. 359-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The role of dam methyltransferase in the control of DNA replication in E. coli

    Boye, E. & Løbner-Olesen, Anders, 7 Sep 1990, In: Cell. 62, 5, p. 981-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Regulation of DNA replication in Escherichia coli

    Boye, E., Lyngstadaas, A., Løbner-Olesen, Anders, Skarstad, K. & Wold, S., 1992, 43 Colloquium Mosbach. Springer Verlag, p. 15-26

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Dam methyltransferase in Escherichia coli: Effects of different enzymatic levels on DNA replication and cell growth

    Boye, E., Lyngstadaas, A. & Løbner-Olesen, Anders, 1992, DNA replication: The Regulatory Mechanisms. P., H., E., F. & M, K. (eds.). Springer Verlag, p. 23-35

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Identification of let-7-regulated oncofetal genes.

    Boyerinas, B., Park, S., Shomron, N., Hedegaard, M. M., Vinther, Jeppe, Andersen, J. S., Feig, C., Xu, J., Burge, C. B. & Peter, M. E., 2008, In: Cancer Research. 68, 8, p. 2587-91 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha

    Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Immunity in the moss Physcomitrella patens

    Bressendorff, Simon, 2012, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  21. Published

    An innate immunity pathway in the moss Physcomitrella patens

    Bressendorff, Simon, Azevedo da Silva, R., Kenchappa, C. S., Ponce de León, I., Olsen, J. V., Rasmussen, M. W., Erbs, G., Newman, Mari-Anne, Petersen, Morten & Mundy, J., 2016, In: The Plant Cell. 28, 6, p. 1328-1342 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Chitin-induced responses in the moss Physcomitrella patens

    Bressendorff, Simon, Rasmussen, M. W., Petersen, Morten & Mundy, J., 2017, Plant pattern recognition receptors: methods and protocols. Shan, L. & He, P. (eds.). Springer, p. 317-324 8 p. (Methods in Molecular Biology, Vol. 1578).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Discrete structural dynamics of pseudo-palindromic motifs control DNA binding of bacterial toxin-antitoxin complexes

    Brodersen, D. E., Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A. & Pedersen, C. N. S., 2017, In: F A S E B Journal. 31, S1, 1 p., 777.2.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4

    Brodersen, K. P., Petersen, Morten, Nielsen, H. B., Zhu, S., Newman, Mari-Anne, Shokat, K. M., Rietz, S., Parker, J. & Mundy, J., 2006, In: Plant Journal. 47, 4, p. 532-546 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The role of salicylic acid in the induction of cell death in Arabidopsis acd11

    Brodersen, K. P., Malinovsky, F. G., Hématy, K., Newman, Mari-Anne & Mundy, J., 2005, In: Plant Physiology. 138, 2, p. 1037-1045 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense.

    Brodersen, P., Petersen, Morten, Pike, H. M., Olszak, B., Skov, Søren, Odum, N., Jørgensen, L. B., Brown, R. E. & Mundy, J., 2002, In: Genes & Development. 16, 4, p. 490-502 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Genetic selection and DNA sequences of 4.5S RNA homologs

    Brown, Stanley, Thon, Genevieve & Tolentino, E., 1989, In: Journal of Bacteriology. 171, 12, p. 6517-20 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells

    Brunati, C., Thomsen, T. T., Gaspari, E., Maffioli, S., Sosio, M., Jabes, D., Løbner-Olesen, Anders & Donadio, S., 2018, In: The Journal of antimicrobial chemotherapy. 73, 2, p. 414-424 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Revised sequence of foxtail mosaic virus reveals a triple gene block structure similar to potato virus X

    Bruun-Rasmussen, M., Madsen, C. T., Johansen, E. & Albrechtsen, M., 2008, In: Archives of Virology. 153, 1, p. 223-226

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Stability of Barley stripe mosaic virus-induced gene silencing in barley.

    Bruun-Rasmussen, M., Madsen, C. T., Jessing, S. & Albrechtsen, M. T., 2007, In: Molecular Plant - Microbe Interactions. 20, 11, p. 1323-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update.

    Bryne, J. C., Valen, E., Tang, M. E., Marstrand, T., Winther, Ole, da Piedade, I., Krogh, Anders, Lenhard, B. & Sandelin, Albin Gustav, 2008, In: Nucleic Acids Research. 36, Database issue, p. D102-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C

    Brügger, K., Chen, L., Stark, M., Zibat, A., Redder, P., Ruepp, A., Awayez, M., She, Q., Garrett, Roger Antony & Klenk, H., 2007, In: Archaea. 2, 2, p. 127-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Sulfolobus genomes: mechanisms of rearrangement and change

    Brügger, K., Peng, Xu & Garrett, Roger Antony, 2006, Archaea: Evolution, physiology and Molecular Biolog.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published

    Correction: The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombination (PLoS ONE (2013) 8, 12 (e82630) DOI: 10.1371/journal.pone.0082630)

    Burgess, R. C., Sebesta, M., Sisakova, A., Marini, V. P. & Lisby, Michael, 24 Jun 2014, In: PLoS ONE. 9, 6, e101095.

    Research output: Contribution to journalComment/debateResearchpeer-review

  35. Published

    Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo

    Burgess, R. C., Lisby, Michael, Altmannova, V., Krejci, L., Sung, P. & Rothstein, R., 2009, In: Journal of Cell Biology. 185, 6, p. 969-81 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombination

    Burgess, R. C., Sebesta, M., Sisakova, A., Marini, V. P., Lisby, Michael, Damborsky, J., Klein, H., Rothstein, R. & Krejci, L., 2013, In: PLoS ONE. 8, 12, p. e82630 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination.

    Burgess, R. C., Rahman, S., Lisby, Michael, Rothstein, R. & Zhao, X., 2007, In: Molecular and Cellular Biology. 27, 17, p. 6153-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Dynamics and stabilization of the human gut microbiome during the first year of life

    Bäckhed, G. F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., Khan, M. T., Zhang, J., Li, J., Xiao, L., Al-Aama, J., Zhang, D., Lee, Y. S., Kotowska, D. E., Colding, C. S., Tremaroli, V. & 7 others, Yin, Y., Bergman, S., Xu, X., Madsen, L., Kristiansen, Karsten, Dahlgren, J. & Wang, J., 2015, In: Cell Host & Microbe. 17, 5, p. 690-703 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system

    Bærentsen, R. L., Nielsen, S. V., Skjerning, R. B., Lyngsø, J., Bisiak, F., Pedersen, J. S., Gerdes, K., Sørensen, Michael Askvad & Brodersen, D. E., 2023, In: eLife. 12, 20 p., RP90400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response

    Bærentsen, R. L., Brodersen, D. E. & ZHANG, YONG, 2019, In: Microbial Cell Factories. 6, 9, p. 450-453

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A High Resolution, High Throughput Approach for Subcellular Spatial Omics

    CHEN, Ao, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 130 p.

    Research output: Book/ReportPh.D. thesisResearch

  42. Published

    CRI-SPA: a high-throughput method for systematic genetic editing of yeast libraries

    Cachera, P., Olsson, H., Coumou, H., Jensen, M. L., Sánchez, B., Strucko, T., Van den broek, M., Daran, J., Jensen, M., Sonnenschein, N., Lisby, Michael & Mortensen, U., 2023, In: Nucleic acids symposium series. 51, 17, 14 p., e91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Antisense inhibition of the Escherichia coli NrdAB aerobic ribonucleotide reductase is bactericidal due to induction of DNA strand breaks

    Campion, C., Charbon, Godefroid, Thomsen, T. T., Nielsen, Peter E. & Løbner-Olesen, Anders, 2021, In: Journal of Antimicrobial Chemotherapy. 76, 11, p. 2802–2814 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Targeting synthesis of the Chromosome Replication Initiator Protein DnaA by antisense PNA-peptide conjugates in Escherichia coli

    Campion, C., Charbon, Godefroid, Nielsen, Peter E. & Løbner-Olesen, Anders, 2024, In: Frontiers in Antibiotics. 3, 10 p., 1384390.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    PICH deficiency limits the progression of MYC-induced B-cell lymphoma

    Castejón-Griñán, M., Albers, E., Simón-Carrasco, L., Aguilera, P., Sbroggio, M., Pladevall Morera, David, Ingham, Andreas, Lim, Ernest Wee Kiat, Guillen-Benitez, A., Pietrini, E., Lisby, Michael, Hickson, Ian David & Lopez-Contreras, Andres, 2024, In: Blood Cancer Journal. 14, 1, 15 p., 16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Genomic context drives transcription of insertion sequences in the bacterial endosymbiont Wolbachia wVulC

    Cerveau, N., Gilbert, C., Liu, C., Garrett, Roger Antony, Greve, P., Bouchon, D. & Cordaux, R., 2015, In: Gene. 564, 1, p. 81-86 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Regulation of telomere metabolism by the RNA processing protein Xrn1

    Cesena, D., Cassani, C., Rizzo, E., Lisby, Michael, Bonetti, D. & Longhese, M. P., 20 Apr 2017, In: Nucleic Acids Research. 45, 7, p. 3860-3874 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Iron chelation increases the tolerance of Escherichia coli to hyper-replication stress

    Charbon, Godefroid, Klitgaard, R. N., Liboriussen, C. D., Thulstrup, Peter Waaben, Maffioli, S. I., Donadio, S. & Løbner-Olesen, Anders, 2018, In: Scientific Reports. 8, 1, 14 p., 10550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli

    Charbon, Godefroid, Campion, C., Chan, S. H. J., Bjørn, L., Weimann, A., da Silva, L. C. N., Jensen, P. R. & Løbner-Olesen, Anders, 27 Jan 2017, In: PLoS Genetics. 13, 1, 26 p., e1006590.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Counting Replication Origins to Measure Growth of Pathogens

    Charbon, Godefroid, Haugan, M. S., Frimodt-Møller, N. & Løbner-Olesen, Anders, 2020, In: Antibiotics. 9, 5, 5 p., 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

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