Functional Genomics

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  1. 2001
  2. Published

    Inhibition of Flp Recombinase by the Topoisomerase I-targeting Drugs, Camptothecin and NSC-314622

    From Frøhlich, R., Hansen, S. G., Lisby, Michael, Grainge, I., Westergaard, O., Jayaram, M. & Knudsen, B. R., 9 Mar 2001, In: Journal of Biological Chemistry. 276, 10, p. 6993-6997 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Residues Within the N-terminal Domain of Human Topoisomerase I Play a Direct Role in Relaxation

    Lisby, Michael, Olesen, J. R., Skouboe, C., Krogh, B. O., Straub, T., Boege, F., Velmurugan, S., Martensen, P. M., Andersen, A. H., Jayaram, M., Westergaard, O. & Knudsen, B. R., 8 Jun 2001, In: Journal of Biological Chemistry. 276, 23, p. 20220-20227 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Rad52 forms DNA repair and recombination centers during S phase

    Lisby, Michael, Rothstein, R. & Mortensen, U. H., 17 Jul 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 15, p. 8276-8282 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    7. Proprioceptive evoked potentials (PEP) in man: Cerebral responses of changing weight loads on the hand

    Arnfred, Sidse Marie , CHEN, Ao, Eder, D. N., Glenthøj, Birte Yding & Hemmingsen, Ralf Peter, Oct 2001, In: Brain and Cognition. 47, 1-2, p. 54-57 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2002
  7. Published

    An Arabidopsis callose synthase.

    Ostergaard, L., Petersen, Morten, Mattsson, O. & Mundy, J., 2002, In: Plant Molecular Biology. 49, 6, p. 559-566 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    An exceptional case of historical outbreeding in African sable antelope populations

    Pitra, C., Hansen, Anders Johannes, Lieckfeldt, D. & Arctander, P., 2002, In: Molecular Ecology. 11, 7, p. 1197-208

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated PCR

    Reid, R. J. D., Lisby, Michael & Rothstein, R., 2002, In: Methods in Enzymology. 350, p. 258-77 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense.

    Brodersen, P., Petersen, Morten, Pike, H. M., Olszak, B., Skov, Søren, Odum, N., Jørgensen, L. B., Brown, R. E. & Mundy, J., 2002, In: Genes & Development. 16, 4, p. 490-502 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    MAP-kinaser--molekylaere transistorer i dyr og planter.

    Petersen, Morten, Brodersen, P. & Mundy, J., 2002, In: Ugeskrift for læger. 164, 24, p. 3184-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Population structure of the African savannah elephant inferred from mitochondrial control region sequences and nuclear microsatellite loci

    Nyakaana, S., Arctander, P. & Siegismund, Hans Redlef, 2002, In: Heredity. 89, 2, p. 90-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

    Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

    Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region

    Nielsen, I. S., Nielsen, Olaf, Murray, J. M. & Thon, Genevieve, 1 Aug 2002, In: Eukaryotic Cell (Online Edition). 1, 4, p. 613-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2003
  17. Published

    A promoter within the E6 ORF of human papillomavirus type 16 contributes to the expression of the E7 oncoprotein from a monocistronic mRNA

    Glahder, J. H., Hansen, C. N., Vinther, Jeppe, Madsen, B. S. & Norrild, B., 2003, In: Journal of General Virology. 84, Pt 12, p. 3429-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    AFV1, a novel virus infecting hyperthermophilic archaea of the genus Acidianus.

    Bettstetter, M., Peng, Xu & Garrett RA, Prangishvili D., G. R. P. D., 2003, In: Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

    Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease

    Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Gene finding with a hidden Markov model of genome structure and evolution.

    Pedersen, J. S. & Hein, J., 2003, In: Bioinformatics. 19, 2, p. 219-27 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Genus-specific protein binding to the large clusters of DNA repeats (short regularly spaced repeats) present in Sulfolobus genomes

    Peng, Xu, Brügger, K., Shen, B., Chen, L., She, Q. & Garrett, Roger Antony, 2003, In: Journal of Bacteriology. 185, 8, p. 2410-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Identification and characterization of a cluster of transcription start sites located in the E6 ORF of human papillomavirus type 16

    Rosenstierne, M. W., Vinther, Jeppe, Hansen, C. N., Prydsoe, M. & Norrild, B., 2003, In: Journal of General Virology. 84, Pt 11, p. 2909-20 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Plants flex their skeletons.

    Foster, R., Mattsson, O. & Mundy, J., 2003, In: Trends in Plant Science. 8, 5, p. 202-4 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Relationships between fuselloviruses infecting the extremely thermophilic archaeon Sulfolobus: SSV1 and SSV2

    Stedman, K. M., She, Q., Phan, H., Arnold, H. P., Holz, I., Garrett, Roger Antony & Zillig, W., 2003, In: Research in Microbiology. 154, 4, p. 295-302 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution

    Samuelsen, C. O., Baraznenok, V., Khorosjutina, O., Spahr, H., Kieselbach, T., Holmberg, Steen & Gustafsson, C. M., 2003, In: Proceedings of the National Academy of Science of the United States of America. 100, 11, p. 6422-6427 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The Arabidopsis lue1 mutant defines a katanin p60 ortholog involved in hormonal control of microtubule orientation during cell growth.

    Bouquin, T., Mattsson, O., Naested, H., Foster, R. & Mundy, J., 2003, In: Journal of Cell Science. 116, Pt 5, p. 791-801 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A human topoisomerase IIα heterodimer with only one ATP binding site can go through successive catalytic cycles

    Skouboe, C., Bjergbaek, L., Østergaard, Vibe Hallundbæk, Larsen, M. K., Knudsen, B. R. & Andersen, A. H., 21 Feb 2003, In: Journal of Biological Chemistry. 278, 8, p. 5768-5774 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

    Lisby, Michael, Mortensen, U. H. & Rothstein, R., Jun 2003, In: Nature Cell Biology. 5, 6, p. 572-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    COP9 signalosome: a provider of DNA building blocks

    Nielsen, Olaf, 15 Jul 2003, In: Current Biology. 13, 14, p. R565-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cell cycle-regulated centers of DNA double-strand break repair

    Lisby, Michael, Antúnez de Mayolo, A., Mortensen, U. H. & Rothstein, R., 10 Sep 2003, In: Cell Cycle. 2, 5, p. 479-83 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2004
  33. Published

    Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development

    Næsted, H., Holm, A., Jenkins, T., Nielsen, H. B., Harris, C. A., Beale, M. H., Andersen, M., Mant, A., Scheller, H. V., Camara, B., Mattsson, O. & Mundy, J., 2004, In: Journal of Cell Science. 117, 20, p. 4807-18 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II

    Bourbon, H. M., Aguilera, A., Ansari, A. Z., Asturias, F. J., Berk, A. J., Bjorklund, S., Blackwell, T. K., Borggrefe, T., Carey, M., Carlson, M., Conaway, J. W., Conaway, R. C., Emmons, S. W., Fondell, J. D., Freedman, L. P., Fukasawa, T., Gustafsson, C. M., Han, M., He, X., Herman, P. K. & 27 others, Hinnebusch, A. G., Holmberg, Steen, Holstege, F. C., Jaehning, J. A., Kim, Y., Kuras, L., Leutz, A., Lis, J. T., Meisterernest, M., Naar, A. M., Nasmyth, K., Parvin, J. D., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, P. W., Stillman, D. J., Strich, R., Struhl, K., Svejstrup, J. Q., Tuck, S., Winston, F., Roeder, R. G. & Kornberg, R. D., 2004, In: Molecular Cell. 14, 5, p. 553-557

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    A comparative method for finding and folding RNA secondary structures within protein-coding regions.

    Pedersen, J. S., Meyer, I. M., Forsberg, R., Simmonds, P. & Hein, J., 2004, In: Nucleic Acids Research. 32, 16, p. 4925-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe

    Bjerling, P., Ekwall, K., Egel, Richard & Thon, Genevieve, 2004, In: Nucleic Acids Research. 32, 15, p. 4421-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    An evolutionary model for protein-coding regions with conserved RNA structure.

    Pedersen, J. S., Forsberg, R., Meyer, I. M. & Hein, J., 2004, In: Molecular Biology and Evolution. 21, 10, p. 1913-22 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Computational method for discovery of estrogen responsive genes.

    Tang, S., Tan, S. L., Ramadoss, S. K., Kumar, A. P., Tang, M. E. & Bajic, V. B., 2004, In: Nucleic Acids Research. 32, 21, p. 6212-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    DNA repair: keeping it together.

    Lisby, Michael & Rothstein, R., 2004, In: Current Biology. 14, 23, p. R994-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Exceptionally diverse morphotypes and genomes of crenarchaeal hyperthermophilic viruses

    Prangishvili, D. & Garrett, Roger Antony, 2004, In: Biochemical Society Transactions. 32, Pt 2, p. 204-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Genomic comparison of archaeal conjugative plasmids from Sulfolobus

    Greve, B., Jensen, S., Brügger, K., Zillig, W. & Garrett, Roger Antony, 2004, In: Archaea. Vol. 1., p. 231-239

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

    Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Morphology and genome organisation of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: A novel virus family, the Globuloviridae

    Häring , M., Peng, Xu & Brugger K., Rachel R., Stetter K.O., Garrett R.A.,Prangishvili D., B. K. ,. R. R. ,. S. K. O. ,. G. R. A. ,. D., 2004, In: Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The fission yeast heterochromatin protein Rik1 is required for telomere clustering during meiosis

    Tuzon, C. T., Borgstrøm, B., Weilguny, D., Egel, Richard, Cooper, J. P. & Nielsen, Olaf, 2004, In: Journal of Cell Biology. 165, 6, p. 759-65 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The Transducer Domain Is Important for Clamp Operation in Human DNA Topoisomerase IIα

    Østergaard, Vibe Hallundbæk, Bjergbaek, L., Skouboe, C., Giangiacomo, L., Knudsen, B. R. & Andersen, A. H., 16 Jan 2004, In: Journal of Biological Chemistry. 279, 3, p. 1684-1691 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    DNA repair

    Fleck, O. & Nielsen, Olaf, 1 Feb 2004, In: Journal of Cell Science. 117, Pt 4, p. 515-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Key role of Ser562/661 in Snf1-dependent regulation of Cat8p in Saccharomyces cerevisiae and Kluyveromyces lactis

    Charbon, Godefroid, Breunig, K. D., Wattiez, R., Vandenhaute, J. & Noël-Georis, I., May 2004, In: Molecular and Cellular Biology. 24, 10, p. 4083-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    DNA damage checkpoint and repair centers

    Lisby, Michael & Rothstein, R., Jun 2004, In: Current Opinion in Cell Biology. 16, 3, p. 328-34 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp 1 p and Stp2p

    Eckert-Boulet, N., Nielsen, P. S., Friis, Carsten, Moreira dos Santos, M., Nielsen, J., Kielland-Brandt, M. C. & Regenberg, Birgitte, 1 Jun 2004, In: Yeast. 21, 8, p. 635-648 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Dissecting the cell-killing mechanism of the topoisomerase II-targeting drug ICRF-193

    Østergaard, Vibe Hallundbæk, Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28100-28105 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Hindering the strand passage reaction of human topoisomerase IIα without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp

    Østergaard, Vibe Hallundbæk, Giangiacomo, L., Bjergbaek, L., Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28093-28099 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

    Lisby, Michael, Barlow, J. H., Burgess, R. C. & Rothstein, R., 17 Sep 2004, In: Cell. 118, 6, p. 699-713 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2005
  54. Published

    A novel rudivirus, ARV1, of the hyperthermophilic archaeal genus Acidianus

    Vestergaard, G. A., Häring, M., Peng, Xu, Rachel, R., Garrett, Roger Antony & Prangishvili, D., 2005, In: Virology. 336, 1, p. 83-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Beringian paleoecology inferred from permafrost-preserved fungal DNA

    Lydolph, M. C., Jacobsen, J., Arctander, P., Gilbert, M Thomas P, Gilichinsky, D. A., Hansen, Anders Johannes, Willerslev, Eske & Lange, L., 2005, In: Applied and Environmental Microbiology. 71, 2, p. 1012-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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