Functional Genomics

Read more
151 - 200 out of 962Page size: 50
  1. 2020
  2. Published

    Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

    Sofos, N., Feng, M., Stella, S., Pape, T., Fuglsang, Anders, Lin, Jinzhong, Huang, Q., Li, Y., She, Q. & Montoya, Guillermo, 2020, In: Molecular Cell. 79, 5, p. 741-757

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Draft Genome of Coelastrum proboscideum (Sphaeropleales, Chlorophyta)

    Liang, H., Wang, H., Xu, Y., Li, L., Melkonian, B., Lorenz, M., Friedl, T., Sahu, S. K., Yu, J., Liu, Huan, Melkonian, M. & Wang, S., 2020, In: Protist. 171, 5, 7 p., 125758.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Role of Efflux Pumps in the Transition from Low-Level to Clinical Antibiotic Resistance

    Ebbensgaard, Anna Elisabeth, Løbner-Olesen, Anders & Frimodt-Møller, Jakob, 2020, In: Antibiotics. 9, 12, 7 p., 855.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The Roles of Bacterial DNA Double-Strand Break Repair Proteins in Chromosomal DNA Replication

    Sinha, A. K., Possoz, C. & Leach, D. R. F., 2020, In: FEMS Microbiology Reviews. 44, 3, p. 351-368

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The draft genome of mandrill (Mandrillus sphinx): an Old World monkey

    Yin, Y., Yang, T., Liu, Huan, Huang, Z., Zhang, Y., Song, Y., Wang, W., Guang, X., Sahu, S. K. & Kristiansen, Karsten, 2020, In: Scientific Reports. 10, 8 p., 2431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The genome of Prasinoderma coloniale unveils the existence of a third phylum within green plants

    Li, L., Wang, S., Wang, H., Sahu, S. K., Marin, B., Li, H., Xu, Y., Liang, H., Li, Z., Cheng, S., Reder, T., Çebi, Z., Wittek, S., Petersen, M., Melkonian, B., Du, H., Yang, H., Wang, J., Wong, G. K-S., Xu, X. & 4 others, Liu, X., Van de Peer, Y., Melkonian, M. & Liu, Huan, 2020, In: Nature Ecology and Evolution. 4, 9, p. 1220-1231

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Thresholds for clinical importance were defined for the European Organisation for Research and Treatment of Cancer Computer Adaptive Testing Core-an adaptive measure of core quality of life domains in oncology clinical practice and research

    Giesinger, J. M., Loth, F. L. C., Aaronson, N. K., Arraras, J. I., Caocci, G., Efficace, F., Grønvold, Mogens, van Leeuwen, M., Petersen, Morten, Ramage, J., Tomaszewski, K. A., Young, T., Holzner, B. & EORTC Quality of Life Group, E. Q. O. L. G., 2020, In: Journal of Clinical Epidemiology. 117, p. 117-125 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Thresholds for clinical importance were established to improve interpretation of the EORTC QLQ-C30 in clinical practice and research

    Giesinger, J. M., Loth, F. L. C., Aaronson, N. K., Arraras, J. I., Caocci, G., Efficace, F., Grønvold, Mogens, van Leeuwen, M., Petersen, Morten, Ramage, J., Tomaszewski, K. A., Young, T., Holzner, B. & EORTC Quality of Life Group, E. Q. O. L. G., 2020, In: Journal of Clinical Epidemiology. 118, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Type II and type IV toxin-antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population

    Horesh, G., Fino, C., Harms, A., Dorman, M. J., Parts, L., Gerdes, K., Heinz, E. & Thomson, N. R., 2020, In: Nucleic Acids Research. 48, 8, p. 4357-4370 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Type IV CRISPR-Cas systems are highly diverse and involved in competition between plasmids

    Pinilla Redondo, Rafael, Mayo-Muñoz, D., Russel, J., Garrett, Roger Antony, Randau, L., Sørensen, Søren Johannes & Shah, S. A., 2020, In: Nucleic Acids Research. 48, 4, p. 2000-2012 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing

    Gummesson, Bertil, Shah, S. A., Borum, A. S., Fessler, M., Mitarai, Namiko, Sørensen, Michael Askvad & Svenningsen, Sine Lo, 2020, In: Frontiers in Genetics. 11, 17 p., 144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Virulence, Resistance, and Genomic Fingerprint Traits of Vibrio cholerae Isolated from 12 Species of Aquatic Products in Shanghai, China

    Fu, H., Yu, P., Liang, W., Kan, B., Peng, Xu & Chen, L., 2020, In: Microbial Drug Resistance. 26, 12, p. 1526-1539 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2019
  16. Published

    Development and Psychometric Evaluation of an Item Bank for Computerized Adaptive Testing of the EORTC Insomnia Dimension in Cancer Patients (EORTC CAT-SL)

    Dirven, L., Petersen, Morten, Aaronson, N. K., Chie, W., Conroy, T., Costantini, A., Hammerlid, E., Velikova, G., Verdonck-de Leeuw, I. M., Young, T. & Grønvold, Mogens, 6 Dec 2019, In: Applied Research in Quality of Life. 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells

    Svenningsen, Mikkel Skjoldan, Veress, A., Harms, A., Mitarai, Namiko & Semsey, S., 15 Apr 2019, In: Scientific Reports. 9, 13 p., 6056.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

    Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    (p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch

    ZHANG, YONG, Bærentsen, R. L., Fuhrer, T., Sauer, U., Gerdes, K. & Brodersen, D. E., 2019, In: Molecular Cell. 74, 6, p. 1239-1249, e1-e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    (p)ppGpp-mediated stress response induced by defects in outer membrane biogenesis and ATP production promotes survival in Escherichia coli

    Roghanian, Mohammad, Semsey, S., Løbner-Olesen, Anders & Jalalvand, F., 2019, In: Scientific Reports. 9, p. 1-11 2934.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Escherichia coli belonging to ST131 rarely transfers blactx-m-15 to fecal Escherichia coli

    Thingholm, K. R., Hertz, F. B., Løbner-Olesen, Anders, Frimodt-Møller, N. & Nielsen, K. L., 2019, In: Infection and Drug Resistance. 12, p. 2429-2435

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Schinus terebinthifolia leaf lectin (SteLL) has anti-infective action and modulates the response of Staphylococcus aureus-infected macrophages

    Lima, I. M. D. S. F., Zagmignan, A., Santos, D. M., Maia, H. S., Silva, L. D. S., Cutrim, B. D. S., Vieira, S. L., Filho, C. M. B., de Sousa, E. M., Napoleão, T. H., Krogfelt, K. A., Løbner-Olesen, Anders, Paiva, P. M. G. & da Silva, L. C. N., 2019, In: Scientific Reports. 9, 14 p., 18159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A Novel Fluorescence-Based Screen for Inhibitors of the Initiation of DNA Replication in Bacteria

    Klitgaard, R. N. & Løbner-Olesen, Anders, 2019, In: Current Drug Discovery Technologies. 16, 3, p. 272-277

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A novel type III CRISPR-Cas system in Lactobacilli: Molecular mechanisms and its application potential

    Lin, Jinzhong, 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  25. Published

    A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system

    Pan, S., Li, Q., Deng, Ling, Jiang, S., Jin, X., Peng, N., Liang, Y., She, Q. & Li, Y., 2019, In: RNA Biology. 16, 9, p. 1166-1178

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Antibacterial mechanisms of GN-2 derived peptides and peptoids against Escherichia coli

    Saporito, P., Biljana, M., Løbner-Olesen, Anders & Jenssen, H., 2019, In: Biopolymers. 110, 6, 9 p., e23275.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    CRP Interacts Specifically With Sxy to Activate Transcription in Escherichia coli

    Søndberg, E., Sinha, A. K., Gerdes, K. & Semsey, S., 2019, In: Frontiers in Microbiology. 10, 8 p., 2053.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system

    Guo, T., Zheng, F., Zeng, Z., Yang, Y., Li, Q., She, Q. & Han, W., 2019, In: RNA Biology. 16, 10, p. 1513-1520

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Comparative activity of ceftriaxone, ciprofloxacin and gentamicin as a function of bacterial growth rate probed by Escherichia coli chromosome replication in the mouse peritonitis model

    Haugan, M. S., Løbner-Olesen, Anders & Frimodt-Møller, N., 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 13 p., e-02133-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Comparative genomics for non-O1/O139 Vibrio cholerae isolates recovered from the Yangtze River Estuary versus V. cholerae representative isolates from serogroup O1

    Gong, L., Yu, P., Zheng, H., Gu, W., He, W., Tang, Y., Wang, Y., Dong, Y., Peng, Xu, She, Q., Xie, L. & Chen, L., 2019, In: Molecular Genetics and Genomics. 294, 2, p. 417-430

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families

    Shah, S. A., Alkhnbashi, O. S., Behler, J., Han, W., She, Q., Hess, W. R., Garrett, Roger Antony & Backofen, R., 2019, In: RNA Biology. 16, 4, p. 530-542 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Current View of the Mechanisms Controlling the Transcription of the TOL Plasmid Aromatic Degradation Pathways

    Domínguez-Cuevas, P. & Marqués, S., 2019, Aerobic Utilization of Hydrocarbons, Oils, and Lipids. Rojo, F. (ed.). Springer, p. 573-594 (Handbook of Hydrocarbon and Lipid Microbiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Efflux-Pump Upregulation: From Tolerance to High-level Antibiotic Resistance?

    Frimodt-Møller, Jakob & Løbner-Olesen, Anders, 2019, In: Trends in Microbiology. 27, 4, p. 291-293

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Esc2 promotes telomere stability in response to DNA replication stress

    Jørgensen, S. W., Liberti, S. E., Larsen, N. B., Lisby, Michael, Mankouri, H. W. & Hickson, Ian David, 2019, In: Nucleic Acids Research. 47, 9, p. 4597-4611 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response

    Bærentsen, R. L., Brodersen, D. E. & ZHANG, YONG, 2019, In: Microbial Cell Factories. 6, 9, p. 450-453

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Examination of bacterial growth rate during host infection and its importance for antimicrobial treatment

    Haugan, M. S., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  37. Published

    Fatty acid starvation activates RelA by depleting lysine precursor pyruvate

    Sinha, A. K., Winther, K. S., Roghanian, Mohammad & Gerdes, K., 2019, In: Molecular Microbiology. 112, 4, p. 1339-1349

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Functions of Orc1-2 in the DNA damageresponsive regulation in Sulfolobus islandicus

    Sun, M., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  39. Published

    Gene Expression Changes with Minor Effects on the Population Average Have Major Effects on the Occurrence of Cells with Extreme Protein Concentrations

    Svenningsen, Mikkel Skjoldan, Semsey, S. & Mitarai, Namiko, 2019, In: mSphere. 4, 1, p. 1-6 e00575-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Growth Rate of Escherichia coli During Human Urinary Tract Infection: Implications for Antibiotic Effect

    Haugan, M. S., Hertz, F. B., Charbon, Godefroid, Sahin, B., Løbner-Olesen, Anders & Frimodt-Møller, N., 2019, In: Antibiotics. 8, 3, 12 p., 92.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Guidelines for DNA recombination and repair studies: cellular assays of DNA repair pathways

    Klein, H. L., Bacinskaja, G., Che, J., Cheblal, A., Elango, R., Epshtein, A., Fitzgerald, D. M., Gómez-González, B., Khan, S. R., Kumar, S., Leland, B. A., Marie, L., Mei, Q., Miné-Hattab, J., Piotrowska, A., Polleys, E. J., Putnam, C. D., Radchenko, E. A., Saada, A. A., Sakofsky, C. J. & 28 others, Shim, E. Y., Stracy, M., Xia, J., Yan, Z., Yin, Y., Aguilera, A., Argueso, J. L., Freudenreich, C. H., Gasser, S. M., Gordenin, D. A., Haber, J. E., Ira, G., Jinks-Robertson, S., King, M. C., Kolodner, R. D., Kuzminov, A., Lambert, S. A. E., Lee, S. E., Miller, K. M., Mirkin, S. M., Petes, T. D., Rosenberg, S. M., Rothstein, R., Symington, L. S., Zawadzki, P., Kim, N., Lisby, Michael & Malkova, A., 2019, In: Microbial Cell Factories. 6, 1, p. 1-64

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Inhibition of Type III CRISPR-Cas Immunity by an Archaeal Virus-Encoded Anti-CRISPR Protein

    Bhoobalan, Yuvaraj, Johansen, T. B., Di Cianni, N. & Peng, Xu, 2019, In: Cell. 179, 2, p. 448-458, e1-e11

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

    Turnbull, K. J., Dzhygyr, I., Lindemose, Søren, Hauryliuk, V. & Roghanian, Mohammad, 2019, In: Frontiers in Microbiology. 10, 12 p., 1966.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Investigation of the Sulfolobus islandicus III-B Cmr-α CRISPR-Cas system and SMV1 anti-CRISPR activity

    Guo, T., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  45. Published

    Mating-type switching by homology-directed recombinational repair: a matter of choice

    Thon, Genevieve, Maki, T., Haber, J. E. & Iwasaki, H., 2019, In: Current Genetics. 65, 2, p. 351-362

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Molecular evidence for origin, diversification and ancient gene duplication of plant subtilases (SBTs)

    Xu, Y., Wang, S., Li, L., Sahu, S. K., Petersen, Morten, Liu, X., Melkonian, M., Zhang, G. & Liu, Huan, 2019, In: Scientific Reports. 9, 10 p., 12485.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Phylogenomics Provides New Insights into Gains and Losses of Selenoproteins among Archaeplastida

    Liang, H., Wei, T., Xu, Y., Li, L., Sahu, S. K., Wang, H., Li, H., Fu, X., Zhang, G., Melkonian, M., Liu, X., Wang, S. & Liu, Huan, 2019, In: International Journal of Molecular Sciences (Online). 20, 12, 14 p., 3020.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Predicted highly derived class 1 CRISPR-Cas system in Haloarchaea containing diverged Cas5 and Cas7 homologs but no CRISPR array

    Makarova, K. S., Karamycheva, S., Shah, S. A., Vestergaard, G. A., Garrett, Roger Antony & Koonin, E. V., 2019, In: FEMS Microbiology Letters. 366, 7, 5 p., fnz079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

    Bantele, S. C. S., Lisby, Michael & Pfander, B., 2019, In: Nature Communications. 10, p. 1-12 944.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Regulation of BRCA2 by the Protein Phosphatase 2A

    Ambjørn, Sara Marie, 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  51. Published

    Regulation of Ribonucleotide Reductase and Screening for Species-Specific Inhibitors in Fission Yeast

    Løvschal, K. V., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  52. Published

    Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

    Nielsen, S. V., Turnbull, K. J., Roghanian, Mohammad, Bærentsen, R., Semanjski, M., Brodersen, D. E., Macek, B. & Gerdes, K., 2019, In: mBio. 10, 3, 16 p., e-01138-19.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 4 5 6 7 8 ...20 Next